Journal of Mahatma Gandhi Institute of Medical Sciences最新文献

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Accuracy of magnetic resonance imaging in assessing types of degeneration in leiomyomas 磁共振成像在评估平滑肌瘤变性类型中的准确性
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-07-01 DOI: 10.4103/jmgims.jmgims_40_20
Sheema Posh, Suhail Rafiq, Farzana Manzoor, O. ashraf, Musaib Ahmad
{"title":"Accuracy of magnetic resonance imaging in assessing types of degeneration in leiomyomas","authors":"Sheema Posh, Suhail Rafiq, Farzana Manzoor, O. ashraf, Musaib Ahmad","doi":"10.4103/jmgims.jmgims_40_20","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_40_20","url":null,"abstract":"Background: Leiomyomas are the most common benign uterine neoplasms arising from smooth muscle cells. Magnetic resonance (MR) imaging is the most accurate imaging technique for detecting and localizing leiomyomas. As leimyomas grow, they may outgrow their blood supply resulting in various types of degeneration such as myxoid, hyaline, cystic, red, and calcification. Degenerated leiomyomas have variable appearances on T2-weighted images and contrast-enhanced images. Materials and Methods: This was a retrospective hospital-based study done in Government Medical College, Srinagar, from January 2018 to December 2019. The study included 78 patients with more than 2 cm pathologically proven fibroids who underwent myomectomy or hysterectomy and preoperative MR imaging (MRI). We assessed the accuracy of MR for picking degeneration in fibroids. Aim and Objective: The aim and objective of this study is to determine the sensitivity, specificity, positive, and negative predictive value of MRI in assessing degeneration in uterine fibroids. Results: The sensitivity, specificity, positive and negative predictive values of MRI in assessing degeneration in uterine fibroids were 60%, 93.7%, 85.7%, and 78.9% respectively. Menorrhagia followed by dysmenorrhea was the most common presenting symptom. Conclusion: MRI has average sensitivity and very good specificity for picking fibroid degenerations. MRI has high accuracy for picking up myxoid, cystic, and red degeneration.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"99 - 102"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49500514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Siamese twins: Thoracopagus – A rare congenital anomaly 暹罗双胞胎:胸膜炎——一种罕见的先天性畸形
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-07-01 DOI: 10.4103/jmgims.jmgims_60_17
Insha Khan, M. Ilyas, S. Shah, C. Saldanha
{"title":"Siamese twins: Thoracopagus – A rare congenital anomaly","authors":"Insha Khan, M. Ilyas, S. Shah, C. Saldanha","doi":"10.4103/jmgims.jmgims_60_17","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_60_17","url":null,"abstract":"A case report of conjoined twins (thoracopagus-conjoined neck, thorax, and upper abdomen) diagnosed by routine ultrasonography in a 26-year-old G2 P1 pregnant female at 19 weeks of gestation is discussed. The pregnancy was terminated at this gestation with explained prognosis to the patient and consent of the family.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"116 - 118"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49438574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the national capacity and preparedness to respond to the coronavirus disease 2019 outbreak 评估应对2019年冠状病毒病暴发的国家能力和准备情况
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-07-01 DOI: 10.4103/jmgims.jmgims_19_20
S. Shrivastava, P. Shrivastava
{"title":"Assessment of the national capacity and preparedness to respond to the coronavirus disease 2019 outbreak","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/jmgims.jmgims_19_20","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_19_20","url":null,"abstract":"","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"119 - 120"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48859728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Segmental neurofibromatosis: A report of a rare case 节段性神经纤维瘤病1例报告
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-07-01 DOI: 10.4103/jmgims.jmgims_63_17
Pratiksha Sonkusale, S. Kar, Pooja Bonde, Komal Ramteke
{"title":"Segmental neurofibromatosis: A report of a rare case","authors":"Pratiksha Sonkusale, S. Kar, Pooja Bonde, Komal Ramteke","doi":"10.4103/jmgims.jmgims_63_17","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_63_17","url":null,"abstract":"Neurofibromatosis (NF) is a genetic disorder with an autosomal-dominant inheritance mainly affecting the growth of the cells of the neural tissues. Segmental NF (SNF), a rare variant of NF (NF type V), is characterized by café-au-lait macules and freckles or neurofibromas limited to one segment or one region of the body. A 26-year-old married female presented with asymptomatic café-au-lait macules and freckles involving the left cervical and thoracic region. The lesions did not cross the midline. Family history was not positive. There was no history of consanguineous marriage. There was no systemic involvement. We report this case as a rare entity of NF along with multidermatomal involvement.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"113 - 115"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43509797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dysbiosis of gut microbiota and human diseases 肠道微生物群失调与人类疾病
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-07-01 DOI: 10.4103/jmgims.jmgims_59_19
Sangeeta Huidrom, M. Beg
{"title":"Dysbiosis of gut microbiota and human diseases","authors":"Sangeeta Huidrom, M. Beg","doi":"10.4103/jmgims.jmgims_59_19","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_59_19","url":null,"abstract":"Gut microbiota of humans harbour a complex and dynamic community of more than 100 trillion beneficial microbes. Recent advances in tools and techniques of microbial analysis have made it possible to understand better the important role played by gut microbiota in the human body. The composition of gut microbiota depends on many factors, such as the mode of delivery of the baby, environmental conditions, antibiotic usage, age, and diet. Homeostasis of gut microbiota is important for maintaining good health as it influences human nutrition, metabolism, and immune function, while dysbiosis of the gut microbiota is associated with various gastrointestinal and metabolic disorders, such as inflammatory bowel disease, obesity, type 2 diabetes, colon cancer, and dysregulation of the immune system. Clinical evidences have shown that diseases caused by imbalance gut microbiota can be treated by probiotics. However, more research work is required to get insightful knowledge of what kind of particular microbes and underlying molecular mechanisms are responsible for a particular disease.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"66 - 71"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42241705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Need for abundant caution in prophylactic application of chloroquine and hydroxychloroquine for viral infections including COVID-19: Possibility of increased susceptibility 在包括COVID-19在内的病毒感染中预防使用氯喹和羟氯喹需要非常谨慎:易感性增加的可能性
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-04-06 DOI: 10.2139/ssrn.3570607
Ritesh Singh
{"title":"Need for abundant caution in prophylactic application of chloroquine and hydroxychloroquine for viral infections including COVID-19: Possibility of increased susceptibility","authors":"Ritesh Singh","doi":"10.2139/ssrn.3570607","DOIUrl":"https://doi.org/10.2139/ssrn.3570607","url":null,"abstract":"Significant interest in application of Chloroquine (CQ) and Hydroxychloroquine (HCQ) for prophylaxis and treatment of COVID-19 has been recently reported throughout the world. In the light of this, it has become important to revisit the mechanisms of action, as well as clinical evidence for efficacy of CQ and HCQ in similar viral infections. We note that while some evidence exists for therapeutic efficacy of CQ and HCQ in mitigating morbidities associated with virus-induced inflammation and immuno-hyperactivity, abundant caution is necessary in expecting prophylactic efficacy in the light of therapeutic evidence. In particular, we intend to draw urgent attention to the fact that the same immuno-suppresive and immuno-modulatory properties of CQ and HCQ which render them useful as therapeutic agents in viral pneumonia and cytokine storm syndrome, are also expected to make them dangerous prophylactic agents against viral infections. We also intend to draw attention to some other potential concerns associated with widespread prophylactic usage of CQ and HCQ.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68608493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Trend and seasonality of infectious diseases – An overview from a tertiary care hospital of West Bengal, India 传染病的趋势和季节性——来自印度西孟加拉邦一家三级护理医院的综述
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-01-01 DOI: 10.4103/jmgims.jmgims_56_19
R. Roy, Baisakhi Maji, A. Haldar, T. Chatterjee
{"title":"Trend and seasonality of infectious diseases – An overview from a tertiary care hospital of West Bengal, India","authors":"R. Roy, Baisakhi Maji, A. Haldar, T. Chatterjee","doi":"10.4103/jmgims.jmgims_56_19","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_56_19","url":null,"abstract":"Background: Most of the developing countries still suffer from a high burden of communicable diseases. The paucity of proper data about the current trends and seasonal variations of different infectious diseases (IDs) further prevents the policy makers from devising an effective, preventive, and curative response. Hospital ID wards are a useful source of surveillance data that can indicate changing health-care requirements. Materials and Methods: A retrospective analysis of inpatient hospital database of past 5 years (January 2014–December 2018) was done to identify the pattern and trend of different IDs including seasonal variations. Results: Among 127,762 admissions during 2014–2018, diarrheal diseases (87%) were most common, followed by dengue (6.6%), chicken pox (2.4%), measles (1.6%), and diphtheria (1.2%). Measles and chicken pox cases had shown peak during February–May months, whereas dengue in September–October, and swine flu cases were at peak during the winter season. Over the past 5 years, the admission rate of measles cases showed a cyclical rising trend, chicken pox showed an inclining trend, whereas tetanus showed a declining trend. The admission trend of diphtheria cases was more or less similar throughout consecutive years except a fall in 2018. The admission rate of dengue cases showed a steep rise in 2016, followed by gradual decline in respective years. However, swine flu admission rate showed a zigzag pattern over the past 5 years. Conclusion: The review of hospital records provided information regarding the overall burden and pattern of admissions in the IDs hospital.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"39 - 44"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45899941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of H1N1 influenza outbreak in a remote hilly region of North India 印度北部偏远丘陵地区H1N1流感疫情调查
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-01-01 DOI: 10.4103/jmgims.jmgims_59_18
V. Barwal, H. Thakur, B. Bhushan, S. Thakur, Ankit Chaudhary, Dr Gopal Ashish Sharma
{"title":"Investigation of H1N1 influenza outbreak in a remote hilly region of North India","authors":"V. Barwal, H. Thakur, B. Bhushan, S. Thakur, Ankit Chaudhary, Dr Gopal Ashish Sharma","doi":"10.4103/jmgims.jmgims_59_18","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_59_18","url":null,"abstract":"Background: Influenza A/H1N1/2009 Pandemic strain is one of the reemerging viral diseases. Localized outbreaks of various magnitudes continue to occur globally as well as in India. An outbreak of this disease took place in a remote area of North India. We investigated it to find out the etiology and distribution and recommend appropriate control measures. Materials and Methods: On urgent directions from the State Health Department, a team was constituted to investigate the outbreak. The team mapped the area and undertook house to house search of cases on 17th–19th May 2017. Line listing of cases was prepared. Respiratory samples of 13 symptomatic cases were taken. Eight blood samples were also collected for viral serology and blood cultures. Results: Line listing consisted of 61 cases. Attack rate was 25.2/1000 population. Mean age was 13.9 years with a median of 4 years. All cases had fever, followed by cough (67.2%) and sore throat (44.3%). Case–fatality ratio was 1.6%. Epidemic curve showed a common source continuous epidemic with limited spread. The average incubation period was 5 days. Four samples were positive for Influenza A/H1N1/2009 Pandemic strain and two were positive for Influenza A (nonswine). Conclusion: It was a confirmed outbreak of pH 1N1. A similar outbreak here in April 2010 suggests the endemic presence of this virus, and in future, as the susceptible population again rises to a threshold level, another outbreak may occur in this area. Utmost priority should be accorded for continuous monitoring and surveillance along with intensified IEC activities.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"23 - 27"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43109146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Journal of Mahatma Gandhi Institute of Medical Sciences: A silver journey of 25 years 圣雄甘地医学科学研究所杂志:25年的银色旅程
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-01-01 DOI: 10.4103/jmgims.jmgims_6_20
O. Gupta
{"title":"Journal of Mahatma Gandhi Institute of Medical Sciences: A silver journey of 25 years","authors":"O. Gupta","doi":"10.4103/jmgims.jmgims_6_20","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_6_20","url":null,"abstract":"","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"4 - 5"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41408857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Delay in starting therapy in drug-resistant tuberculosis – An insight 耐药结核病开始治疗的延迟——一种见解
Journal of Mahatma Gandhi Institute of Medical Sciences Pub Date : 2020-01-01 DOI: 10.4103/jmgims.jmgims_18_19
Ambarish Joshi, S. Kant, R. Kushwaha, P. Ish
{"title":"Delay in starting therapy in drug-resistant tuberculosis – An insight","authors":"Ambarish Joshi, S. Kant, R. Kushwaha, P. Ish","doi":"10.4103/jmgims.jmgims_18_19","DOIUrl":"https://doi.org/10.4103/jmgims.jmgims_18_19","url":null,"abstract":"Introduction: The Revised National Tuberculosis Control Programme (RNTCP) ensures a prompt diagnosis and effective treatment of all tuberculosis (TB) patients with drug-resistant TB via decentralized drug sensitivity testing (DST). This study was taken in to find out the cause of delays in initiation of treatment. Material and Methods: This cross-sectional observational study included a questionnaire-based interview and retrospective analysis of records of the concerned patients with an aim to explore the reasons associated with this delay. Results: A delay was arbitrarily defined as a time period of more than 15 days from the date of sputum collection for DST to the date of admission. It considered of two parts, one due to lapse in system regarding implementation of program and other due to the lapses in the part of the patient. Out of 402 patients enrolled in the study, 252 (62.7%) sought treatment after the prescribed period and were categorized as delayed and comprised the Group I of study. The remaining 150 (37.3%) were those who sought treatment within the prescribed period and were and were termed in-time treatment seekers and thus comprised Group II of study. Delay in communication of results to DOTS centre and in-patient tracing was the most common reason for delay while unwillingness to avail treatment against the expectation was the least common reason. Conclusions: Undefined time for communication of DST results and patient tracing in PMDT services are the major cause of delay. Strengthening the communication skills of the care providers through expanding DST services at sub-district levels, regular training of care providers, setting district level information cells, creating mobile apps, and involving volunteers who are representatives of the local community is the need of the hour.","PeriodicalId":32484,"journal":{"name":"Journal of Mahatma Gandhi Institute of Medical Sciences","volume":"25 1","pages":"19 - 22"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43466610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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