Perinatologia y Reproduccion Humana最新文献_第7页

Estómago intratorácico en un recién nacido: ¿hernia hiatal o verdadero esófago corto congénito? 新生儿胸内胃:裂孔疝还是真正的先天性短食道?

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-11-20 DOI: 10.1016/j.rprh.2017.10.016

B. Martinez-Leo, J. Vidal-Medina, A. Castillo-Aguirre, V. Portugal-Moreno, M. Vargas-Gomez

引用次数: 0

Infecciones por gérmenes atípicos en el recién nacido hospitalizado en un centro de tercer nivel de atención. Un problema creciente 在三级护理中心住院的新生儿的非典型细菌感染。日益严重的问题

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-11-24 DOI: 10.1016/j.rprh.2017.10.003

S. Carrera-Muiños , C. Michel-Macías , L.A. Fernández-Carrocera , G. Cordero-González , E. Yllescas-Medrano , E. Corral-Kassian

{"title":"Infecciones por gérmenes atípicos en el recién nacido hospitalizado en un centro de tercer nivel de atención. Un problema creciente","authors":"S. Carrera-Muiños , C. Michel-Macías , L.A. Fernández-Carrocera , G. Cordero-González , E. Yllescas-Medrano , E. Corral-Kassian","doi":"10.1016/j.rprh.2017.10.003","DOIUrl":"10.1016/j.rprh.2017.10.003","url":null,"abstract":"<div><h3>Introduction</h3><p>The United States Center for Disease Control and Prevention (CDC) estimates a chlamydial infection prevalence of 5% in adolescents. Colonisation by Mycoplasma is estimated to be between 5% and 75%, and by Ureaplasma from 35% to 90%.</p><p>The objective was to describe the frequency of atypical infections in newborns admitted to a tertiary hospital, as well as risk factors and clinical manifestations.</p></div><div><h3>Material and methods</h3><p>A retrospective, descriptive study was conducted between January and December 2015. All newborns with a positive culture or PCR for an atypical germ during hospital stay were included.</p></div><div><h3>Results</h3><p>A total of 75 (19%) positive cultures/PCR were observed out of a total of 388 samples. Mean maternal age was 28.7, and 25% presented with PROM (premature rupture of membranes)>18h, with chorioamnionitis in 9.3% of cases. The mean birth weight was 1478g and the mean gestational age was 31 weeks. Mechanical ventilation was required in 56% of patients. Mean hospital stay was 60 days, and eosinophilia was present in 60% of cases. Conjunctivitis and pneumonia were the recognised pathologies caused by atypical microbes. There were 18 cases of conjunctivitis, all of them caused by chlamydia trachomatis (23%). Sixty-four (85.3%) cases of pneumonia were diagnosed, of which 75% were caused by chlamydia, 22% by Ureaplasma, and Mycoplasma in 3% of cases. Seven patients presented with pneumonia and conjunctivitis.</p></div><div><h3>Conclusion</h3><p>Of the study population, 23% presented with conjunctivitis and 85% had pneumonia. Chlamydia trachomatis was the most frequently isolated microbe (75%). Eosinophilia was associated in 60% of cases.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"31 1","pages":"Pages 34-38"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46494034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Metaloproteinasa de la matriz 9 cervicovaginal en el segundo trimestre para la predicción de parto pretérmino 妊娠中期宫颈阴道基质金属蛋白酶用于预测早产

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-11-20 DOI: 10.1016/j.rprh.2017.10.011

E. Reyna-Villasmil, J. Mejia-Montilla, N. Reyna-Villasmil, D. Torres-Cepeda, J. Santos-Bolívar, M. Rondón-Tapía, A. Fernández-Ramírez

{"title":"Metaloproteinasa de la matriz 9 cervicovaginal en el segundo trimestre para la predicción de parto pretérmino","authors":"E. Reyna-Villasmil, J. Mejia-Montilla, N. Reyna-Villasmil, D. Torres-Cepeda, J. Santos-Bolívar, M. Rondón-Tapía, A. Fernández-Ramírez","doi":"10.1016/j.rprh.2017.10.011","DOIUrl":"10.1016/j.rprh.2017.10.011","url":null,"abstract":"<div><h3>Objective</h3><p>To establish the prognostic usefulness of cervicovaginal fluid concentrations of matrix metalloproteinase-9 in the second trimester for the prediction of preterm delivery.</p></div><div><h3>Materials and method</h3><p>A case-control study was conducted on 613 pregnant women attending the Dr. Urquinaona Central Hospital, Maracaibo, Venezuela. Group A (n=52) women with preterm birth and group B (n=561) women with term birth, (control group) of pregnant women who had term deliveries. The cervicovaginal concentrations of matrix metalloproteinase-9 were compared between the 2 groups.</p></div><div><h3>Results</h3><p>The mean gestation age at measurement of cervicovaginal concentrations of matrix metalloproteinase-9 was 26.2±1.1 weeks in Group A, and 25.9±1.1 weeks in Group B (<em>P</em>          <!-->ng/mL had an under the curve value of 0.59, with a sensitivity of 75.0%, specificity of 41.1%, positive predictive value of 10.5%, and negative predictive value of 94.6%.</p></div><div><h3>Conclusion</h3><p>Cervicovaginal matrix metalloproteinase-9 concentrations in second trimester are elevated in pregnant women, who later had pre-term delivery, but are not useful for predicting this.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"31 1","pages":"Pages 10-15"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48138231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Un tributo a Roberto Caldeyro-Barcia, considerado el pionero de la Perinatología 向Roberto Caldeyro-Barcia致敬，他被认为是围产期学的先驱

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-11-24 DOI: 10.1016/j.rprh.2017.10.012

A. Zárate, L. Manuel-Apolinar, M. Hernández-Valencia

{"title":"Un tributo a Roberto Caldeyro-Barcia, considerado el pionero de la Perinatología","authors":"A. Zárate, L. Manuel-Apolinar, M. Hernández-Valencia","doi":"10.1016/j.rprh.2017.10.012","DOIUrl":"10.1016/j.rprh.2017.10.012","url":null,"abstract":"<div><p>Roberto Caldeyro-Barcia was born in Montevideo in 1921, and studied medicine graduating as medical physician in 1947. He was accepted as associate investigator at the Instituto de Fisiologia under Professor Hermogenes Alvarez, who was working on the effect of uterine activity on the foetal cardiac pulse during delivery. The amniotic pressure was registered by the use of a small catheter introduced inside the amniotic cavity. Thereby, Dr. Caldeyro-Barcia proposed to introduce a micro-catheter directly into the uterine muscle to obtain more specific information on the uterus contraction and its effect on foetal heart activity. It was observed that heart pulse was decreased in those cases of hypoxia. These decreases were called DIP I and II. Therefore, the theory was that during delivery hypoxia had a deleterious action on foetal oxygenation, which was registered and graduated as “Montevideo units”. Two years later Eduard H. Hon working in Yale University confirmed these findings, and it was the beginning of foetal heart beat monitoring during delivery in the whole world. Dr. Caldeyro-Barcia was presented worldwide with research awards. Moreover, he became the Director of the South-American Centre of Perinatology and President of the International Gynaeco-Obstetrics Federation. He was very fond of Mexico, a place that he visited several times, and had a close and warm relationship with Luis Castelazo-Ayala. Dr. Caldeyro-Barcia was considered an accomplished scientist, an exemplary mentor, and a leader in perinatology.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"31 1","pages":"Pages 39-43"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44552754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cambios en el directorio editorial de la revista Perinatología y Reproducción Humana, sin pérdida de su visión, responsabilidad y compromisos 《围产期与人类生殖》杂志编辑目录的变化，但不丧失其视野、责任和承诺

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-12-18 DOI: 10.1016/j.rprh.2017.11.002

R. Figueroa Damián

引用次数: 0

Efecto de los esteroides posnatales en el neurodesarrollo en recién nacidos ventilados ≤ de 1,500 g 产后类固醇对通气≤1500 g新生儿神经发育的影响

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-12-06 DOI: 10.1016/j.rprh.2017.10.008

E. Yllescas Medrano , S.V. Lara Barbosa , L.A. Fernández Carrocera , G. Cordero González , S. Carrera Muiños

{"title":"Efecto de los esteroides posnatales en el neurodesarrollo en recién nacidos ventilados ≤ de 1,500 g","authors":"E. Yllescas Medrano , S.V. Lara Barbosa , L.A. Fernández Carrocera , G. Cordero González , S. Carrera Muiños","doi":"10.1016/j.rprh.2017.10.008","DOIUrl":"10.1016/j.rprh.2017.10.008","url":null,"abstract":"<div><h3>Introduction</h3><p>The use of steroids in the post-natal period is a common practice, although it is still controversial in neonatology due to its association with adverse effects and risk of neurodevelopment sequelae.</p></div><div><h3>Material and methods</h3><p>A retrospective, observational, analytical study was conducted including patients weighing less than 1500g that received a steroid protocol for extubation between 2008 and 2010 and compared with a control group. Neurodevelopment was evaluated using the Bayley II scale at one and two years of age, as well as an analysis of the demographic variables and morbidity.</p></div><div><h3>Results</h3><p>A total of 132 patients were included, with 46 in the study group and 86 in the control group. No differences were found in the demographic variables, although the length of stay was significantly longer in the study group. An increased risk for arterial hypertension, grade II intraventricular haemorrhage, Patent Ductus Arteriosus, bronchopulmonary dysplasia, and retinopathy was found in the study group. There was no difference as regards blindness, hearing loss, cerebral palsy, and leukomalacia. At 2 years of age an increase in the risk for mild mental development impairment was found in the control group and increased risk for significant delay in psychomotor development in the study group.</p></div><div><h3>Conclusions</h3><p>Post-natal low dose steroids are effective to accomplish extubation in patients that are ventilation dependent. Significant psychomotor development changes were found at 2 years of age, with no evidence of leukomalacia or cerebral palsy.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"31 1","pages":"Pages 16-20"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.10.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47210338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Células madre, una nueva alternativa médica 干细胞，一种新的医学替代品

Perinatologia y Reproduccion Humana Pub Date : 2017-03-01 Epub Date: 2017-11-21 DOI: 10.1016/j.rprh.2017.10.013

G.A. Pimentel-Parra, B. Murcia-Ordoñez

引用次数: 4

Concentraciones plasmáticas de isoprostano-8 en preeclampsia y eclampsia 异前列腺素-8在子痫前期和子痫中的血浆浓度

Perinatologia y Reproduccion Humana Pub Date : 2016-10-01 Epub Date: 2017-07-01 DOI: 10.1016/j.rprh.2016.10.001

E. Reyna-Villasmil, D. Torres-Cepeda, J. Santos-Bolívar, J. Mejia-Montilla, N. Reyna-Villasmil, A. Fernández-Ramírez

{"title":"Concentraciones plasmáticas de isoprostano-8 en preeclampsia y eclampsia","authors":"E. Reyna-Villasmil, D. Torres-Cepeda, J. Santos-Bolívar, J. Mejia-Montilla, N. Reyna-Villasmil, A. Fernández-Ramírez","doi":"10.1016/j.rprh.2016.10.001","DOIUrl":"10.1016/j.rprh.2016.10.001","url":null,"abstract":"<div><h3>Objective</h3><p>To compare plasma vascular 8-isoprostane concentrations in pregnant women with pre-eclampsia and eclampsia.</p></div><div><h3>Material and methods</h3><p>Patients attending the Hospital Central Dr. Urquinaona in Maracaibo, Venezuela, were selected. The study included 30 patients with mild pre-eclampsia (group A), 30 patients with severe pre-eclampsia (group B), and 30 patients with eclampsia (group C). A control group was also included, consisting of 30 healthy pregnant women (group D) of similar age and body mass index to studied groups. Only nulliparous patients were included. Plasma samples were collected for the 8-isoprostane determination from all patients before delivery, and in the studied groups immediately after diagnosis.</p></div><div><h3>Results</h3><p>Statistically significant differences were found in gestational age between groups B and C compared with the control group (p<.05). Higher values of plasma 8-isoprostane were observed in severe pre-eclampsia patients (366.0±29.7pg/mL), as well as in eclampsia patients (354.2±26.9pg/mL). Lower values were found in mild pre-eclampsia patients (302.2±31.6pg/mL). The studied groups had significantly higher values of plasma 8-isoprostane compared with controls (209.3±19.1pg/mL; p<.05). Linear regression analysis found that the factor that was significantly associated with 8-isoprostane concentrations was the 24-h urine protein level (p<.05).</p></div><div><h3>Conclusion</h3><p>Eclampsia and pre-eclampsia patients had higher plasma 8-isoprostane concentrations than healthy normotensive pregnant women.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"30 4","pages":"Pages 180-185"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2016.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55287827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Función cardiaca fetal en preeclámpticas tratadas con parches de nitroglicerina 硝化甘油贴片治疗产前胎儿心脏功能

Perinatologia y Reproduccion Humana Pub Date : 2016-10-01 Epub Date: 2017-07-01 DOI: 10.1016/j.rprh.2016.10.005

E. Reyna-Villasmil, J. Mejia-Montilla, J. Santos-Bolívar, Y. Navarro-Briceño, D. Torres-Cepeda, N. Reyna-Villasmil, A. Fernández-Ramírez, M. Colmenares-Vega

{"title":"Función cardiaca fetal en preeclámpticas tratadas con parches de nitroglicerina","authors":"E. Reyna-Villasmil, J. Mejia-Montilla, J. Santos-Bolívar, Y. Navarro-Briceño, D. Torres-Cepeda, N. Reyna-Villasmil, A. Fernández-Ramírez, M. Colmenares-Vega","doi":"10.1016/j.rprh.2016.10.005","DOIUrl":"10.1016/j.rprh.2016.10.005","url":null,"abstract":"<div><h3>Objective</h3><p>To identify modifications foetal cardiac function in pre-eclampsia patients treated with nitroglycerin patches.</p></div><div><h3>Method</h3><p>The sample consisted of 50 pre-eclampsia nulliparous patients with pregnancies of more than 25 weeks who attended the obstetric emergency service at Hospital Central Dr. Urquinaona, Maracaibo, Venezuela. Maternal haemodynamic changes and cardiac functions by M-mode, pulsed-wave, and tissue Doppler echocardiography were evaluated. Treatment consisted of 5mg transdermal nitroglycerin patches, applied in the anterior thoracic and lumbar region of patients for 12hours (total time of 48hours). After 24hours and 48hours of treatment beginning, maternal haemodynamic and foetal echocardiography variables were evaluated. All parameters were evaluated in each patient.</p></div><div><h3>Results</h3><p>Mean age of patients was 24.4±3.9 years-old, and mean gestational age at beginning of research was 33.2±1.7 weeks. Treatment with nitroglycerin patches produced significant reduction in maternal blood pressure and a significant increase in maternal heart rate in both periods of evaluation (p<.0001). There were observed no changes in general foetal echocardiographic findings, echocardiographic findings in both ventricles and tissue Doppler values after 24hours and 48hours of treatment compared with values previous to treatment (p=ns).</p></div><div><h3>Conclusion</h3><p>The use of transdermal nitroglycerin patches in pre-eclampsia patients did not produce significant changes in foetal cardiac function.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"30 4","pages":"Pages 159-166"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2016.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55288088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estudio comparativo sobre la efectividad del hipoclorito de sodio al 6% vs. la solución bromo-cloro-dimetil-hidantoína para la desinfección en ambientes hospitalarios 6%次氯酸钠与溴氯二甲基海因溶液在医院环境中消毒效果的比较研究

Perinatologia y Reproduccion Humana Pub Date : 2016-10-01 Epub Date: 2017-07-03 DOI: 10.1016/j.rprh.2017.06.001

R. Galván Contreras , R.A. Ruiz Tapia , E. Segura Cervantes , R.M.A. Cortés Aguilar

{"title":"Estudio comparativo sobre la efectividad del hipoclorito de sodio al 6% vs. la solución bromo-cloro-dimetil-hidantoína para la desinfección en ambientes hospitalarios","authors":"R. Galván Contreras , R.A. Ruiz Tapia , E. Segura Cervantes , R.M.A. Cortés Aguilar","doi":"10.1016/j.rprh.2017.06.001","DOIUrl":"10.1016/j.rprh.2017.06.001","url":null,"abstract":"<div><p>There is a risk of spreading multiple microorganisms in the hospital environment, with the possibility of the development nosocomial infections. The surfaces can contribute to cross-contamination through the hands of health professionals and the instruments that could be contaminated when they come into contact with those surfaces.</p></div><div><h3>Objective</h3><p>To evaluate the effectiveness of 6% sodium hypochlorite versus a disinfectant solution of bromine-chloro-dimethyl-hydantoin to eliminate pathogens on the surfaces of different hospital environments.</p></div><div><h3>Materials and methods</h3><p>A prospective, cross-sectional, analytical, and comparative study was designed to evaluate the effectiveness of the cleaning of surfaces in hospital areas with 6% sodium hypochlorite at various dilutions.</p></div><div><h3>Results</h3><p>Samples were taken from a total of 21 surfaces of different areas. In the surfaces disinfected with the solution bromine-chloro-dimethyl-hydantoin, and sodium hypochlorite, several microorganisms grew in 13/21, and 9/21, respectively, before the disinfection process. After application of disinfectants, the microorganisms grew in 0/21, and 2/21 surfaces, respectively, which was non-significant.</p></div><div><h3>Conclusions</h3><p>The two surface disinfectants were effective, and there were no differences between their disinfecting effectiveness.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"30 4","pages":"Pages 145-150"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2017.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55288283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1