The Avicenna Medical Journal最新文献

Body Image In Female Medical Students, Syarif Hidayatullah State Islamic University, Jakarta, Indonesia: Descriptive Study 女医科学生的身体形象，Syarif Hidayatullah州立伊斯兰大学，印度尼西亚雅加达:描述性研究

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.27315

Tasya Salsabila, Marita Fadhilah, I. Noor

{"title":"Body Image In Female Medical Students, Syarif Hidayatullah State Islamic University, Jakarta, Indonesia: Descriptive Study","authors":"Tasya Salsabila, Marita Fadhilah, I. Noor","doi":"10.15408/avicenna.v3i1.27315","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.27315","url":null,"abstract":"Background: Body image issues can be a problem for undergraduate female college students. It happened because women pay more attention to their physical appearance than men. In addition, the ages of undergraduate female college students are generally in the young adult age range, where young adult women are found to often experience problems related to body image. Furthermore, some characteristics of campus life may cause female students to be more susceptible to body image concerns. This study aimed to describe the body image in preclinical female students of the Faculty of Medicine, Syarif Hidayatullah State Islamic University Jakarta. Methodology: This study is an observational analytic study with a cross-sectional approach that applied to preclinical female students of the Faculty of Medicine, Syarif Hidayatullah State Islamic University Jakarta, which was selected using the cluster random sampling method. Data were collected by looking at respondents' answers to The Body Appreciation Scale-2 (BAS-2) questionnaire to assess the body. Results: In this study, 120 respondents were collected from the class of 2018, 2019, and 2020 with the age range of 18-22 years. Based on the results of this study, it is known that the majority of research respondents have a negative body image (58.33%). Conclusion: The majority of research respondents have a negative body image (58.33%).","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122185348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Health-Seeking Behavior of Diabetes Mellitus Patients during the COVID-19 Pandemic in Brebes Regency 新冠肺炎大流行期间布雷布市糖尿病患者就诊行为分析

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.27325

Hiro Putra Faisal, Chrestella Adiyatma, Dwi Tyastuti

{"title":"The Health-Seeking Behavior of Diabetes Mellitus Patients during the COVID-19 Pandemic in Brebes Regency","authors":"Hiro Putra Faisal, Chrestella Adiyatma, Dwi Tyastuti","doi":"10.15408/avicenna.v3i1.27325","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.27325","url":null,"abstract":"Background: The COVID-19 pandemic in Indonesia has impacted patients with non-communicable diseases such as Diabetes Mellitus (DM). The impacts include health services, treatment management, and patients' health-seeking behavior. This study aims to determine the DM patients' health-seeking behavior in the Salem sub-district, Brebes district, Central Java.Methods: This research was a qualitative descriptive study conducted cross-sectionally using a survey. The purposive sampling technique was employed to obtain the data with a total sample of 106 respondents.Results: Most DM patients still visited health facilities during the pandemic (73%). Some efforts to control DM were regularly taking medication (27.7%) and maintaining a healthy diet (34%). However, most respondents stated that they have uncontrolled blood glucose levels (54.7%). During the pandemic, respondents communicated with health workers (75.5%), via telephone (64.2%), and through messaging applications (45.3%). In addition, they search information, especially when they felt symptoms (90.6%), and tried to find information about complications due to the coronavirus (68.9%) with the source from health workers (94.3%). Most respondents had good access (99.1%).Conclusion: The COVID-19 pandemic has resulted changes in DM patients' health-seeking behavior through all aspects. This study shows that most respondents visited health facilities, made efforts to control DM by taking the medication regularly and maintaining a healthy diet, and had high adherence to medication. In addition, respondents had an easy access to health information and communicate with health workers via telephone and messaging applications. The majority of respondents sought information about diabetes and its relationship with COVID-19 during the pandemic.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127972540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association between the rs35874116 Gene TAS1R2 Polymorphism with Caries Index rs35874116基因TAS1R2多态性与龋病指数的关系

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.27319

Pelangi Mumtazdhia, A. Maskoen, B. Laksono, W. Ardini

{"title":"The Association between the rs35874116 Gene TAS1R2 Polymorphism with Caries Index","authors":"Pelangi Mumtazdhia, A. Maskoen, B. Laksono, W. Ardini","doi":"10.15408/avicenna.v3i1.27319","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.27319","url":null,"abstract":"Background: Dental caries is a multifactorial disease influenced by complex genetic and environmental factors. At least 27 gene polymorphisms have been identified that are associated with caries risk. Polymorphisms of genes encoding taste receptors, such as the TAS1R2 gene, can cause individual differences in perception and sensitivity to sweet tastes. Research shows that the TAS1R2 gene polymorphism is associated with the consumption of sweet foods, which affects increasing caries risk. This study aims to determine the relationship between the TAS1R2 gene rs35874116 polymorphism and the caries index in Tangerang Selatan population. Methods: This study is observational with a cross-sectional method involving 266 research subjects (45 males and 221 females; 20-55 years). DNA was extracted from venous blood using the Genomic DNA Mini Kit from Geneaid and the genotyping process using the rhAmp-SNP assay kit, which was analyzed using RT-PCR. Dental caries was assessed by calculating D(decayed), M(missing), and F(filled) on permanent teeth. The hypothesis between the TAS1R2 genotype and the DMF-T index was tested using the Mann-Whitney test, while the comparison between the TAS1R2 genotype and caries risk was tested using Kruskal-Wallis' test. The results of the study were considered significant if p<0.05. Results: The minor allele frequency was 16.5%. The proportion of TT, TC, and CC genotypes were 71.%, 24.1%, and 4.5%, respectively. According to WHO classification, the DMF-T index of all research subjects was 5.62, a high category. The group of subjects with the CC genotype had a higher DMF-T index (7.08; very high) than the group of subjects with the CT genotype (6.05; high) and TT (5.38; high). CT and TT genotypes with high risk were significantly lower than those with low-moderate caries risk. Conclusion: there is no significant association between the TAS1R2 gene polymorphism rs35874116 with the caries index value in the people in South Tangerang.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128296143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Ramadan Fasting on Serum Malondialdehyde Levels as Indicator of Oxidative Stress and Cellular Damage 斋月禁食对血清丙二醛水平作为氧化应激和细胞损伤指标的影响

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.19716

Annisa Nadia Utami, Risahmawati . ., M. –

{"title":"The Effect of Ramadan Fasting on Serum Malondialdehyde Levels as Indicator of Oxidative Stress and Cellular Damage","authors":"Annisa Nadia Utami, Risahmawati . ., M. –","doi":"10.15408/avicenna.v3i1.19716","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.19716","url":null,"abstract":"Background: Ramadan fasting is one of five pillars of Islam. Fasting is to refrain from eating and drinking from sunrise (sahur) to sunset (ifthar). Ramadan fasting has been shown to impact on body systems in different manners. One of the benefits of Ramadan fasting is protection against oxidative stress and cellular damage. Malondialdehyde (MDA) is a product of free radicals (hydroxil radicals) with polyunsaturated fatty acids (PUFAs) produced from lipid peroxidation of cell membranes. This paper aims to determine the effect of Ramadan fasting on serum MDA levels.Methods: The design of this study is quasiexperimental with one group pre and post design. The sample of this study was 16 preclinical students of FK UIN Syarif Hidayatullah Jakarta who performed Ramadan fasting for 17 consecutive days. Blood samples were taken 1 day before Ramadan fasting and 18 days of Ramadan fasting to measure serum MDA levels. The study was conducted in the biochemical laboratory of FK UIN Syarif Hidayatullah.Results: The mean serum MDA levels before fasting was 0.90 ± 0.54 nmol/mL. The median value of serum MDA levels after fasting was 0.43 nmol/mL, with a range between 0.03 - 2.75 nmol/mL. Ramadan fasting decreases serum MDA levels, but the decrease that occurs on the 17th day of Ramadan fasting was not significant (p> 0.05). There was an increase in serum MDA levels in 4 subjects (25%) after Ramadan fasting.Conclusion: Ramadan fasting can reduce serum MDA levels as a marker of oxidative stress and cell damage. Further study is needed to investigate the various results in serum MDA levels after fasting.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"10 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120905131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation Between Physical Activity, Body Composition, And Micronutrition Intake In Patients Of Knee Osteoarthritis At The Medical Rehabilitation Clinic, Fatmawati Hospital Jakarta In 2021 2021年雅加达Fatmawati医院医学康复诊所膝关节骨关节炎患者的身体活动、身体成分和微量营养素摄入之间的相关性

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.27066

Wilis Laksari Putri Adjie, David Renardo Tidja

{"title":"Correlation Between Physical Activity, Body Composition, And Micronutrition Intake In Patients Of Knee Osteoarthritis At The Medical Rehabilitation Clinic, Fatmawati Hospital Jakarta In 2021","authors":"Wilis Laksari Putri Adjie, David Renardo Tidja","doi":"10.15408/avicenna.v3i1.27066","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.27066","url":null,"abstract":"Background : Osteoarthritis (OA) is a degenerative joint disease associated with joint cartilage damage that usually occurs in the aging process. This study is to analyze the correlation between physical activity, body composition, and the micronutrients intake such as vitamin C, D, E, and Calsium the patients with knee OA at the Medical Rehabilitation Clinic (MRC) at Fatmawati Hospital, Jakarta in 2021.Methods: This is a cross sectional quantitative research. The samples were 45 patients who have been diagnosed with knee osteoarthritis in outpatient medical rehabilitation clinic at Fatmawati General Hospital Jakarta who met the inclusion criteria.Results : the results of statistical tests showed that there was a significant difference in the average percentage of body fat with the gradation of OA patients, p value = 0.004. However, there was no significant difference between the average physical activity score, and intake of macronutrients (energy, protein, fat and carbohydrates), BCAAs (arginine and histidine), and intake of micronutrients (vitamin C, vitamin D, vitamin D, vitamin E and Calcium)Conclusion: Percent body fat is the variable with the highest correlation among other factors.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128205918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Screening of Congenital Heart Disease in Neonates: a Literature Review on Five Studies 新生儿先天性心脏病的临床筛查:五项研究的文献综述

The Avicenna Medical Journal Pub Date : 2022-10-19 DOI: 10.15408/avicenna.v3i1.27326

Bentito Zulyan Pamungkas, P. Widaryo

{"title":"Clinical Screening of Congenital Heart Disease in Neonates: a Literature Review on Five Studies","authors":"Bentito Zulyan Pamungkas, P. Widaryo","doi":"10.15408/avicenna.v3i1.27326","DOIUrl":"https://doi.org/10.15408/avicenna.v3i1.27326","url":null,"abstract":"Background: Diagnosing Congenital Heart Disease (CHD), particularly critical CHD in newborns, could be difficult but crucial, since the field of congenital heart surgery has shifted from initial palliation followed by final correction at a later age to stressing early repair even in the youngest individuals. Although echocardiography remains the gold standard for diagnosing CHD, simple clinical examination may be helpful in screening neonates who require further investigation and treatment. In this study, we searched and reviewed the literature on clinical screening for CHD using a simple, affordable tool that is readily available in primary health care facilities, to prove that early simple clinical examination would help physician to screen for asymptomatic CHD.Methods: We searched articles on google scholars that discuss clinical screening of CHD in neonates. Inclusion criteria is articles published within five years and exclusion criteria is articles published older than five years.Results: We found five articles eligible and pick consecutively. We found that pulse oximetry sensitivity and specificity ranged from 21.54%-77.3% and 82.65%-99.9%, respectively. Cardiac auscultation with murmur of grade ≥2 as count as positive, having high range of sensitivity and specificity, with sensitivity ranged from 17.3%-89.58% and specificity ranged from 47.36%-99.69%. When pulse oximetry and cardiac auscultation combined, three studies found that the sensitivity and specificity increased dramatically, 89.9%-95.5%, 94.7%-99.37%, respectively. Conclusion: Both cardiac auscultation and pulse oximetry was an easy, feasible method with readily available basic tools at all hospital with acceptable sensitivity and specificity to screening CHD before suspected neonates undergo echocardiography, therefore making CHD diagnosed more effective and efficient. ","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117210167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Adequacy of Hemodialysis and Anemia in Chronic Kidney Diseases (Ckd) Patients Undergoing Hemodialysis in Dialysis Unit, Fatmawati Hospital 法塔玛瓦蒂医院透析部慢性肾病患者血液透析充分性与贫血的关系

The Avicenna Medical Journal Pub Date : 2022-06-04 DOI: 10.15408/avicenna.v2i2.17754

Leo Ginting, A. Aziz, W. Wulandari, Dwi Budi Lasono

{"title":"The Relationship Between Adequacy of Hemodialysis and Anemia in Chronic Kidney Diseases (Ckd) Patients Undergoing Hemodialysis in Dialysis Unit, Fatmawati Hospital","authors":"Leo Ginting, A. Aziz, W. Wulandari, Dwi Budi Lasono","doi":"10.15408/avicenna.v2i2.17754","DOIUrl":"https://doi.org/10.15408/avicenna.v2i2.17754","url":null,"abstract":"Background: Anemia is a common problem that often occurs in patients with CKD undergoing hemodialysis. 56.5% of hemodialysis patients were still have anemia, while on the other hand, the achievement of hemodialysis. adequacy only reached 52.7%. Disparity that data is the basis for this research. The aim of this study is to analysis the relationship between the achievement of hemodialysis adequacy with the incidence of anemia in patients with CKD undergoing hemodialysis.Methods: This study uses a descriptive correlation with a cross sectional approach to the analysis of the independent variable (HD Adequacy) and the dependent variable (Anemia). The relationship between these variables was tested using the Chi Square test.Result: The study was conducted on 134 hemodialysis patients aged 13-86 years, the most common vascular access was AV fistula (68.7%), and women were the most respondents (55.2%). The Kt / V value in this study was 1.67 (1.03-2.75) and an adequate one was 54.5%. Adequate URR reached 80.6% with a mean of 75.13 ± 6.38. The incidence of anemia reached 53.7% with the Hb value at 8.93 ± 2.82 mg / dl. The results of the Chi Square test showed that HD adequacy (Kt / V and URR) with the incidence of anemia had P values of 0.670 and 0.217.Conclusion: There is no significant relationship between HD adequacy and the incidence of anemia","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127087569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Protective Role of 14-3-3 Protein in Pathological Cardiac Hypertrophy Through The Regulation of Endoplasmic Reticulum Stress: Role of Calreticulin 14-3-3蛋白通过调节内质网应激对病理性心肌肥厚的潜在保护作用:钙网蛋白的作用

The Avicenna Medical Journal Pub Date : 2022-06-04 DOI: 10.15408/avicenna.v2i2.25441

Flori R. Sari, R. Thandavarayan, V. Soetikno

{"title":"Potential Protective Role of 14-3-3 Protein in Pathological Cardiac Hypertrophy Through The Regulation of Endoplasmic Reticulum Stress: Role of Calreticulin","authors":"Flori R. Sari, R. Thandavarayan, V. Soetikno","doi":"10.15408/avicenna.v2i2.25441","DOIUrl":"https://doi.org/10.15408/avicenna.v2i2.25441","url":null,"abstract":"Introduction: 14-3-3 protein plays an important role in protecting cardiac cells from hypertrophy and endoplasmic reticulum stress during pressure overload elicited by aortic banding (AB) surgery; however, the relation among these protective roles is largely unknown. Methods: We investigated the in vivo role of 14-3-3 protein in two protocols involving C57/BL-6 mice and dominant negative (DN) 14-3-3η mice subjected to three- or seven-days pressure overload stimulation by applying AB surgery. The protein expressions of cardiac hypertrophy and ER stress markers, including atrial natriuretic peptide (ANP), galectin-3, glucose-regulated protein (GRP)78, calreticulin as well as 14-3-3 protein was analyzed by western blot. Results: Three- or seven-day pressure overload stimulation significantly increased the heart weight/body weight (HW/BW) ratio; cardiomyocyte diameter; and the protein expression levels of ANP, GRP78 as well as 14-3-3 in the C57/BL-6 mice. Partial inactivation of 14-3-3 protein in the DN 14-3-3η mice significantly increased the protein expression of ANP, Galectin-3, GRP78, and calreticulin after three- or seven-days AB surgery. Conclusion: These results suggest that 14-3-3 protein, as a molecular chaperone, protects against pathological cardiac hypertrophy, at least in part, by maintaining the normal ER function through the regulation of GRP78 and calreticulin.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129335302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Covid-19 Case with Mild Pneumonia Covid-19合并轻度肺炎病例

The Avicenna Medical Journal Pub Date : 2022-06-04 DOI: 10.15408/avicenna.v2i2.20399

Mukhtar Ikhsan

{"title":"Covid-19 Case with Mild Pneumonia","authors":"Mukhtar Ikhsan","doi":"10.15408/avicenna.v2i2.20399","DOIUrl":"https://doi.org/10.15408/avicenna.v2i2.20399","url":null,"abstract":"Background: On December 31, 2019, WHO China Country Office reported a case of pneumonia of unknown etiology in Wuhan City, China. On January 7, 2020, China identified pneumonia of unknown etiology as a grew type of coronavirus (coronavirus disease, COVID-19).Case report: A 39-year-old woman – health care worker - came to the hospital with the chief complaint of coughing three days earlier. Dry cough with no phlegm, fever and no shortness of breath. There are also no other complaints. On physical examination found no abnormalities. There is no history of traveling abroad but there is a history of contact with sufferers of COVID-19 when treating patients. Patients diagnosed as acute respiratory infection were given cefixim 2 x 200 mg for 5 days, paracetamol if necessary and vitamins. Chest X-ray examination is normal while CT X-ray examination without contrast shows a picture of ground glass opacity (GGO). The PCR swab was found to be positive. The patient was diagnosed as positive for COVID-9 with Mild Pneumonia. The patient underwent independent isolation by taking the hydrochloroquin sulfate on day 1: 2 x 2 tab, days 2 - 14: 2 x 1 tab. In addition, the patient also took 1 x 1000 mg of Vitamin C supplements, 1 x 200 IU of vitamin D3 and 1 x 20 mg of Zinc.Results:Clinical symptoms are getting better. On the chest CT scan, the GGO image has improved. The PCR swab turned negative. The patient with COVID-19 with Mild Pneumonia cured.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134210895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of 12 Weeks Vitamin D Supplementation (Alphacalcidol) on Blood Pressure in Elderly Women Patients 补充12周维生素D (α骨化醇)对老年妇女血压的影响

The Avicenna Medical Journal Pub Date : 2022-06-04 DOI: 10.15408/avicenna.v2i2.23785

A. Zaki, N. Nabila, M. D. Widjajakusumah, W. Ardini, Mery Nitalia

{"title":"Effect of 12 Weeks Vitamin D Supplementation (Alphacalcidol) on Blood Pressure in Elderly Women Patients","authors":"A. Zaki, N. Nabila, M. D. Widjajakusumah, W. Ardini, Mery Nitalia","doi":"10.15408/avicenna.v2i2.23785","DOIUrl":"https://doi.org/10.15408/avicenna.v2i2.23785","url":null,"abstract":"Background : Cardiovascular disease have overtaken communicable disease for being the main killer worldwide. Hypertension or high blood pressure is one of the risk factors. Elderly women statistically have a high prevalence of hypertension. Vitamin D is known to affect blood pressure and many studies showed the association between vitamin D and blood pressure with varying result. This study aim to evaluate the effect of vitamin D supplementation (alphacalcidol) for 12 weeks and change in blood pressure of elderly women patients in community health service clinic (KPKM) Medical Faculty Syarif Hidayatullah State Islamic University of Jakarta (FK UIN Jakarta), with pre and hypertension grade 1 patients in majority. Methods : Analytical pre-post study design was conducted as a part of an RCT (Randomized Controlled Trial) studies with 106 participants of elderly women (45 intervention group, 61 control group).Results : Vitamin D deficiency in the intervention group significantly decreased post-supplementation from 22.2% to 8.9%. Subgroup analysis showed the decrease in blood pressure is greater in the subgroup middle-age elderly than young-age elderly category. Even though there was a significant change in the diastolic blood pressure in the subgroup of middle-age elderly post supplementation (p=0.03), Mann-Whitney statistical analysis showed that 12 weeks vitamin D supplementation (alphacalcidol) did not significantly effect the pre and post systolic nor diastolic blood pressure (p>0,05). Conclusion : The study did not found significant effect of 12 weeks Vitamin D (alphacalcidol) supplementation on blood pressure in elderly women patients.","PeriodicalId":322290,"journal":{"name":"The Avicenna Medical Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122907233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0