Journal of Dhaka Medical College最新文献

{"title":"Correlation of Duration of Hair Loss with Trace Element Level in Hair Loss Patients","authors":"F. Rahman, Q. Akhter, N. Yeasmin, F. Sultana, S. Tabassum, T. Habib, T. Akter, Sunjida Akter, Zulfiquar Seraj, Fardous Khan","doi":"10.3329/JDMC.V29I1.51167","DOIUrl":"https://doi.org/10.3329/JDMC.V29I1.51167","url":null,"abstract":"Background: Hair loss is a worldwide problem with significant prevalence in the developed countries. Although many pathophysiological factors have been involved in the development of hair loss, its etiology is still unclear. Trace elements. Objective: To assess duration of hair loss with serum iron level in alopecia. Methods: This cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during January 2017 to December 2017. Serum iron level was estimated by flame atomic absorption spectrophotometry of thirty five newly diagnosed hair loss patients aged 18 to 45 years were study group and thirty five ages, sex and BMI matched healthy subjects were control group. Both male and female was assessed by analyzing time. In this study, the duration of hair loss was 1 to 18 months. Duration of hair loss in study group was divided in two groups such as ≤2 months and >2 months. Patients were selected from Department of Dermatology and Venerology, Dhaka Medical College Hospital, Dhaka. For statistical analysis Unpaired Student’s‘t’ test, Chi square tests and Pearson’s correlation coefficient (r) tests were","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121965736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of amiodarone in the treatment of ventricular arrhythmias in patients with coronary artery disease in Bangladesh","authors":"D. Adhikary, S. Saha, M. Mahmood, A. I. Joarder, C. Singha, Mohammad Walidur Rahman, Hashimul Ahsan, F. I. Khaled, S. Banerjee, Faria Mahbuba, Akhlak Ahmed","doi":"10.3329/JDMC.V29I2.51192","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51192","url":null,"abstract":"Background: Ventricular arrhythmias (VA) are among the most feared complications of coronary artery disease (CAD) and one of the major contributors of death in CAD patients. Antiarrhythmic drug (AAD) therapy is required for recurrent significant VA in the absence of need for further revascularization. But all AADs do not have the same efficacy against life threatening VA and supraventricular arrhythmias (SVAs). Methodology: All (50) patients admitted in the department of Cardiology, BSMMU with ventricular arrhythmias with CAD fulfilling the inclusion and exclusion criteria were included in the study. Informed written consent was taken from each patient before enrollment. Detailed history was taken and relevant physical examinations were done. Loading dose followed by maintenance dose of amiodarone was given and recorded. Relevant lab investigations were performed and recorded in predesigned semi-structured data collection sheet. Symptomatic improvement was assessed, relevant physical examination was done and lab investigations were performed at 1, 3 and 6 month follow up. After editing data analysis was carried out by using the Statistical Package for Social Science (SPSS) version 23.0 windows software. Results: The mean age was found 57.7±8.0 years with a range of 45 to 78 years. Almost two third (62.0%) patients were male and 19(38.0%) patients were female. Male female ratio was 1.6:1. Almost three fourth (74.0%) patients had chest pain, 15(30.0%) had palpitation and 11(22.0%) had shortness of breath. Two third (66.0%) patients had hypertension, 23(46.0%) had dyslipidemia, 17(34.0%) had smoking and 9(18.0%) had diabetes mellitus. Twenty nine (58.0%) patients had family history of IHD. The difference was statistically significant (p<0.05) when compared to baseline. Regarding arrhythmia, 45(90.0%) patients was found to have PVC in baseline and 3(6.4%) at 6 month. The reduction of PVC and VT at six month were statistically significant (p<0.05) when compared to baseline. Regarding outcome 2(4.1%) patients died, one patient dropped out due to thyroid dysfunction and 47 were alive. Conclusion: In conclusion it was found that different forms of ventricular arrhythmias like PVCs, VT were significantly reduced gradually with amiodarone therapy at 6 month follow up. DOI: https://doi.org/10.3329/jdmc.v29i2.51192 J Dhaka Med Coll. 2020; 29(2) : 158-164 1. Dr. Dipal Krishna Adhikary, Associate Professor, Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka. 2. Dr. Sujoy Kumar Saha, Resident (Phase-B), Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka. 3. Prof. Manzoor Mahmood, Professor, Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka. 4. Dr. Md. Ariful Islam Joarder, Assistant Professor, Department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka. 5. Dr. Chayan Kumar Singha, Medical Officer, Department of Cardiology, Bangabandhu Sheikh Mujib Medical University,","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"28 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127474169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Thyroid Dysfunction in Type 2 Diabetes Mellitus","authors":"P. Biswas, G. Saha, M. S. Hossain, N. Uddin, Muhammad Faizur Rahman, Nur-Wa-Bushra Jahan, Ashrafuzzaman, M. Mazumder, Shuvranu Ghosh, P. Paul, A. Chowdhury","doi":"10.3329/JDMC.V29I2.51190","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51190","url":null,"abstract":"Aim: The study was undertaken with an objective to know the thyroid functions in Type 2 diabetics and to know the spectrum of thyroid dysfunction in Type 2 DM. Methods: The present study included 68OPD and IPD patients of Type 2 DM who attended the Department of General Medicine at Dhaka Medical College Hospital Dhaka. Detailed history and examination were done, fasting blood samples of all the subjects were taken and at the same time samples were tested for HbA1C and thyroid profile (T3, T4 and TSH). Result: in this study 68 established diabetics were screened for thyroid disorders by TFT. Abnormal thyroid function was found in 43 T2DM cases and remaining diabetics had normal thyroid function. Among 68 cases low thyroid function was noted in 20 patients and 18 subjects had Sub-clinical hypothyroidism. Hyperthyroidism was noted in 05 patients. Conclusion: Type 2 diabetes mellitus is a major problem all over the world and many patients of Diabetes Mellitus are associated with thyroid dysfunction. So diabetic patients s should be screened for thyroid disorder especially hypothyroidism.","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"os-9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127760612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological Study of Change of Voice","authors":"Arifuzzaman, S. N. Fattah, Mohammad Nazrul Islam, M. Hasan, Monirul Islam, C. Tabassum, S. Monira, Sardar Mohammad Tanvir, Mohammad Farhad","doi":"10.3329/JDMC.V29I2.51185","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51185","url":null,"abstract":"Background: Change of voice is one of the common complaints in ENT practice and hoarseness of voice is the commonest symptom of changed voice quality. Hoarseness is invariably the earliest manifestation of conditions directly or indirectly affecting the voice apparatus. Though most common causes of hoarseness are benign and vocal abuse is the commonest among them, but we should always investigate for more sinister pathology like malignancy. Objectives: To find out the symptoms, signs and pathological incidence, leading to change of voice for early diagnosis and interventional purpose. Methods: Total 87 patients of change of voice, studied in 06 months duration from 1 January 2016 to 30 June 2016 in the Department of ENT & Head-Neck Surgery, Dhaka Medical College Hospital, Dhaka. The cases were selected according to the eligibility criteria by purposive sampling. Then the data were collected by the active participation of the patients interviewed by the preformed proforma of data collection sheet. Results: Maximum number of cases of change of voice were due to carcinoma larynx (37.93%), then chronic laryngitis (20.99%), followed by vocal cord nodules (19.54%) and vocal cord polyps (8.05%.). Laryngopharyngeal reflux was found in 45.95% patients of chronic laryngitis. Males were affected more than females (1.81:1). Most of the patients were in the age group of 21 to 50 years. Peak incidence was in the 4th decade. Labourers/ daily wage earners formed the predominant group. Majority of patients were from low socioeconomic class. Smoking, vocal abuse, smoking and infections were the common predisposing factors. Conclusion: Hoarseness of voice is just a symptom with a very diverse etiology. The etiological data varies in different geographical location and from one center to other, so every case should be carefully and thoroughly evaluated to know the diagnosis and underlying pathology for early and prompt management.","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126038974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative predictors of Ossicular Discontinuity in non-Cholesteatoma Chronic Otitis Media","authors":"K. L. Saha, Nibash Chandra Ghosh, N. Akhtar, Debesh Chandra Talukder","doi":"10.3329/JDMC.V29I1.51171","DOIUrl":"https://doi.org/10.3329/JDMC.V29I1.51171","url":null,"abstract":"Background: Though ossicular discontinuity is more common in cases of cholesteatoma, it may happen in non-cholesteatoma COM. The long process of incus is more frequently involved ossicle. Peroperative assessment of ossicular integrity is the gold standard way. But the discontinuity of the ossicular chain can be assumed before surgery by analyzing perforation edge adherent to medial wall and wide air-bone gap The purpose of the study was to find out the preoperative findings which can predict the ossicular discontinuity in non-cholesteatoma cases. Methods: This cross-sectional study was conducted in the department of Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University from January 2013 to June 2014. 81 patients of COM without cholesteatoma were selected as per inclusion and exclusion criteria. Relevant data were collected in a predesigned data collection sheet and analyzed with standard statistical method. Statistically significant inferred for P value <0.05. No groups whose ability to give voluntary informed consent questionable was not included. No potential risks exist in designed this study. Results: Air-bone gap > 40 dB was found in 60% cases of ossicular discontinuity, followed by air bone gap 31-40 dB(20%), 21-30 dB(13.33%) and 11-20 dB( 6.67%) respectively. So ossicular discontinuity was more in higher air-bone gap group and it was statistically highly significant (p<0.001). Perforation edge attached to medial wall where ossicular discontinuity was 93.3% and perforation edge free from medial wall was 6.7%.Ossicular discontinuity was higher when perforation edge was found attached to medial wall which was highly statistically significant (p<0.001). Out of 25 granulation tissue cases ossicular discontinuity was found 21(84%) and ossicular chain intact was found 4(16%). That was statistically significant (p<0.01). Conclusion: Non-cholesteatoma COM may cause ossicular disconnection. Majority ossicular discontinuity found when average air bone gap > 40 dB. Ossicular discontinuity was also found more in cases where there is attachment of perforation edge to medial wall, and presence of granulation tissue. If preoperative information can be gathered to determine whether or not the ossicular chain is intact, the patient can be better informed, counseled for ossiculoplasty before surgery.","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"13 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126045321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Missed Diagnosis of Phyllodes Tumour And Its Implications - A Case Report","authors":"P. K. Das, Azm Mahfuzur Rahman, Nayeem Dewan Sina, A. Mamun","doi":"10.3329/JDMC.V29I2.51195","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51195","url":null,"abstract":"Phyllodes tumours are rare fibroepithelial tumours that accounts for less than 1% of all breast tumours. Phyllodes tumours tend to grow quickly but they rarely spread outside the breast. Although most phyllodes tumours are benign, some are malignant and some are borderline. It is often underdiagnosed by pathologists and under treated by surgeon. Its heterogenicity makes phyllodes tumour a challenge for the clinicians and the pathologists. Accurate preoperative diagnosis by Fine Needle Aspiration Cytology or by Core biopsy or peroprative diagnosis by Frozen section biopsy is essential for adequate surgical treatment. This case describes a missed diagnosis of phyllodes tumour both by cytopathologically and histopathologically. \u0000J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 182-184","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124308755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Electrophysiological Profile of Carpal Tunnel Syndrome: A Study in a Tertiary Care Hospital","authors":"Kazi Gias Uddin Ahmed, Iftikher Alam, H. Sina, Arifuzzaman, Reaz Mahmud, S. A. Dhali, A. Hossain, Konol Saha, K. A. Azad","doi":"10.3329/JDMC.V29I2.51181","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51181","url":null,"abstract":"Introduction: Carpal tunnel syndrome (CTS) is a clinical syndrome that results from compression of median nerve within the carpal tunnel at the wrist. The aim of this study was to review the clinical and demographic characteristics and electrophysiological patterns of CTS patients who presented to a tertiary care hospital in Bangladesh. \u0000Methodology; A descriptive cross-sectional study was conducted on 150 CTS patients at the neurology department, Dhaka Medical College Hospital between January, 2019 to March , 2020 . All the subjects had clinical evaluation and standardized nerve conduction studies of upper limbs (300 limbs) using the same protocol. \u0000Results: 228 hands were found to have clinical and electrophysiological features consistent with CTS. There was female predominance (90%) and the highest occurrence of CTS was in the 45-55 years age group. Bilateral CTS was found in the majority of cases ie 78 (52%) and the rest had unilateral CTS. Among those with unilateral CTS, right hand was affected more (41, 57%) than left hand (31, 43%). Most of the cases were idiopathic. Neurophysiological studies showed most patients had mild CTS (121 hands, 53%). Most of the cases were idiopathic (102, 68%). Where a risk factor was found diabetes was commonest one (32) followed by hypothyroidism (12) and pregnancy (4). \u0000Conclusion: There was marked female predominance and the 45-55 years age group was predominantly affected. Majority of cases had mild CTS. Bilateral involvement was more common. Right hand was more affected than the left hand. \u0000J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 96-99","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131402669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study of Hepatic Enzymes Between Preeclampsia and Normal Pregnant Women","authors":"F. Afroz, N. Sultana, A. F. M. Moshiur Rahman, N. Zerin, S. M. Samsuzzaman, P. Chowdhury, Muhammad Hasan Andalib, M. Morshed, M. M. Rahman, M. Kamal","doi":"10.3329/JDMC.V29I1.51165","DOIUrl":"https://doi.org/10.3329/JDMC.V29I1.51165","url":null,"abstract":"Background: Preeclampsia is a multisystem disorder, unique to pregnancy that is usually associated with high blood pressure and proteinuria after 20 week of gestation. Abnormal liver function tests occur in 20% to 30% of pregnancies complicated by preeclampsia and are associated with a higher risk of adverse maternal and fetal outcome. Objective: To observe the alteration of hepatic enzymes in preeclampsia. Methods: The present cross-sectional study was carried out in the Department of Biochemistry, Dhaka Medical College, and Dhaka from July 2015 to June 2016. A total number of one hundred pregnant women in third trimester of pregnancy with or without preeclampsia, attending in the outpatient Department of Obstetrics and Gynecology in DMCH, were selected as study subjects. Of them fifty pregnant women in third trimester of pregnancy were with preeclampsia and fifty were normal healthy pregnant women. Estimation of hepatic enzymes like aspartate transaminase, alanine transaminase and gamma glutamyl transferase were done in both preeclampsia and normal pregnant patients and mean values of the variables were compared between them. Results: The mean serum aspartate transaminase level was significantly higher in preeclampsia compared to normal pregnant woman (32.4 ± 15.4 IU/L vs 24.8 ±11.8 IU/L respectively and p 0.007). Serum alanine transaminase level was also significantly higher in preeclampsia than normal pregnancy (38.1±19.9 IU/L vs 18.8±6.95 IU/L, respectively and p < 0.001). Serum gamma glutamyl transferase was also significantly higher in preeclampsia than normal pregnancy (44.7±19.1 IU/L vs 26.6± 6.0 IU/L p < .001). Conclusions: Hepatic enzymes (alanine transaminase, aspartate transaminase, gamma glutamyl transferase) were increased. So routine assessment of these parameters may helpful to prevent worse outcome of preeclampsia patients.","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126456115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern of Electrolyte Abnormalities in Preterm Low Birth Weight Neonates","authors":"S. Islam, M. Banerjee, Tafazzal Hossain Khan, C. K. Shaha, Z. Uddin, R. Ali, Shah Md. Mohaimenul Haq","doi":"10.3329/JDMC.V29I2.51189","DOIUrl":"https://doi.org/10.3329/JDMC.V29I2.51189","url":null,"abstract":"Prematurity and low birth weight contributes to 27.8% of neonatal deaths in rural areas of Bangladesh. Fluid, electrolyte and metabolic abnormalities are the commonest derangements encountered in preterm infants due to their renal immaturity and relatively immature skin. Premature infant are at increased risk of developing dehydration or overhydration. Therefore, high index of suspicion, prompt recognition and thorough understanding of common electrolyte abnormalities are necessary to improve neonatal outcome. Appropriate fluid and electrolyte management is essential for better neonatal outcome. Objectives: To identify the serum electrolytes abnormalities in preterm low birth weight neonates. Methodology: It was a crosssectional study and carried out in the Department of Neonatology, Dhaka Medical College Hospital, Dhaka between January 2017 to August 2017. Information was collected who gave consent and participated in the study willingly. The sample size was 50. Patients admitted in the above mentioned hospital and after meeting the inclusion and exclusion criteria a simple random sampling technique was applied for selecting the study subjects. Results: Fifty preterm LBW neonates fulfilling the inclusion criteria were studied during this study period. Abnormal electrolytes were documented in 20(40%) out of 50 preterm LBW neonates and electrolyte status was normal in 30(60.0%) cases. Of 20 neonates who had abnormal electrolytes, hyperkalemia was the predominant electrolyte abnormality found in 8(16.0%) neonates, hyponatremia was found in 7(14.0%), hypokalemia in 3(6.0%) and hypernatremia","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134445619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic, Clinico-Laboratory Characteristics with Short Outcome among Acute Heart Failure Patients Admitted for First Time in a Tertiary Care Hospital: a Real Life Experience","authors":"A. Kabir, S. J. B. Sayeed, P. Biswas, M. Z. Hossain, Sabrina Rahman, M. Rana, M. Majumder, D. Basak, A. Kabir, Mirza Asif Adnan","doi":"10.3329/JDMC.V28I2.51157","DOIUrl":"https://doi.org/10.3329/JDMC.V28I2.51157","url":null,"abstract":"Acute heart failure is one of the common causes of morbidity & mortality among the patients admitted in hospital. This prospective observational study was done to characterize sociodemographic, clinical & laboratory characteristics with short clinical outcome. Total 110 patients of acute heart failure were included in this study where mean age was 53.88 (± 14.6) years. Majority of the patients were aged between 51-60 years 35 (32%). 79(72%) of them smoker and 12(11%) were alcoholic. Major comorbidities were hypertension 59 (53.63%), ischemic heart disease 42 (38.18%), DM 39(35.45%), chronic kidney disease 25(22.72%). Most common symptoms at presentation were shortness of breath110(100%) along with palpitation 96(87.27%), orthopnea 85(77.27%), paroxysmal nocturnal dyspnea 59(53.63%), ankle edema 71(64.54%), raised JVP 75(68.18%), bilateral basal crepitation on auscultation 80(72.72%), anemia 19 (17.27%) & oliguria 23(20.90%) where mean duration of symptoms was 11 ± 2 days. Lab investigations revealed decreased Hemoglobin (10.71 ± 1.49) g/dl, proteinuria in 31 (28.18%), ketone body 5 (4.5%), raised creatinine in 23(20.93%), hyponatremia 38 (34.54%), hypernatremia 6 (5.45%), hypokalemia 6 (5.45%), hyperkalemia 3 (2.72%). Regarding cardiac events 37(33.63%) encounter myocardial infarction, cardiogenic shock 29(26.36%), Cardiac arrhythmia 27 (24.5%), cardiac arrest 6 (5.45%), non-cardiac events like stroke 6(5.45%), hyperosmolar hyperglycemic state 2(1.8%), diabetic ketoacidosis 5(5.45%), acute kidney injury 23(20.90%). However, among cardiac arrhythmia atrial fibrillation found 13(11.81%) followed by multiple ventricular ectopic 12 (10.90%), ventricular tachycardia 7 (6.36%), Complete heart block 6 (5.45%), variable heart block 4 (3.63%), long QT 2(1.8%). Regarding short clinical outcome 52(47.27%) were improved, 40 (36.36%) had persistent symptoms & rest 18 (16.36%) expired. Most common causes of those deceased person were cardiogenic shock 9(50%) followed by cardiac arrest 6 (6.33%). In conclusion we can say clinical characteristics are more or less similar but those who have reduced ejection fraction with comorbidities are very prone to develop cardiac arrhythmia causing sudden cardiac death in heart failure.","PeriodicalId":320976,"journal":{"name":"Journal of Dhaka Medical College","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134346107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}