SPIE Micro + Nano Materials, Devices, and Applications最新文献_第5页

Automation of daphtoxkit-F biotest using a microfluidic lab-on-a-chip technology 使用微流控芯片实验室技术实现daphtoxkit-F生物测试自动化

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202396

Yushi Huang, D. Nugegoda, D. Wlodkowic

{"title":"Automation of daphtoxkit-F biotest using a microfluidic lab-on-a-chip technology","authors":"Yushi Huang, D. Nugegoda, D. Wlodkowic","doi":"10.1117/12.2202396","DOIUrl":"https://doi.org/10.1117/12.2202396","url":null,"abstract":"An increased rigor in water quality monitoring is not only a legal requirement, but is also critical to ensure timely chemical hazard emergency responses and protection of human and animal health. Bioindication is a method that applies very sensitive living organisms to detect environmental changes using their natural responses. Although bioindicators do not deliver information on an exact type or intensity of toxicants present in water samples, they do provide an overall snapshot and early-warning information about presence of harmful and dangerous parameters. Despite the advantages of biotests performed on sentinel organisms, their wider application is limited by the nonexistence of high-throughput laboratory automation systems. As a result majority of biotests used in ecotoxicology require time-consuming and laborious manual procedures. In this work, we present development of a miniaturized Lab-on-a-Chip (LOC) platform for automation and enhancement of acute ecotoxicity test based on immobilization of a freshwater crustacean Daphnia magna (Daphtoxkit-FTM). Daphnids’ immobilization in response to sudden changes in environment parameters is fast, unambiguous, and easy to record optically. We also for the first time demonstrate that LOC system enables studies of sub-lethal ecotoxic effects using behavioral responses of Daphnia magna as sentinels of water pollution. The system working principle incorporated a high definition (HD) time-resolved video data analysis to dynamically assess impact of the reference toxicant on swimming behavior of D. magna. Our system design combined: (i) microfluidic device for caging of Daphnia sp.; (ii) mechatronic interface for fluidic actuation; (iii) video data acquisition; and (iv) algorithms for animal movement tracking and analysis.","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114638059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Development of the magnetic force-induced dual vibration energy harvester using a unimorph cantilever 采用均匀悬臂梁的磁力感应双振动能量采集器的研制

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202337

M. Umaba, E. Nakamachi, Y. Morita

{"title":"Development of the magnetic force-induced dual vibration energy harvester using a unimorph cantilever","authors":"M. Umaba, E. Nakamachi, Y. Morita","doi":"10.1117/12.2202337","DOIUrl":"https://doi.org/10.1117/12.2202337","url":null,"abstract":"In this study, a high frequency piezoelectric energy harvester converted from the human low vibrated motion energy was newly developed. This hybrid energy harvester consists of the unimorph piezoelectric cantilever, the pendulum and a pair of permanent magnets. One magnet was attached at the edge of cantilever, and the counterpart magnet at the edge of pendulum. The mechanical energy provided through the human walking motion, which is a typical ubiquitous existence of vibration, is converted to the electric energy via the piezoelectric unimorph cantilever vibration. At first, we studied the energy convert mechanism and analyze the performance of novel energy harvester, where the resonance free vibration of unimorph piezoelectric cantilever generated a high electric power. Next, we equipped the counterpart permanent magnet at the edge of pendulum, which vibrates with a very low frequency caused by the human walking. Then the counterpart magnet was set at the edge of unimorph piezoelectric cantilever, which vibrated with a high frequency. This low-to-high frequency convert “dual vibration system” can be characterized as an enhanced energy harvester. We examined and obtained average values of voltage and power in this system, as 8.31 mV and 0.33 μW. Those results show the possibility to apply for the energy harvester in the portable and implantable Bio-MEMS devices.","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122388174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Ultrafast charge generation and relaxation dynamics in methylammonium lead bromide perovskites 甲基溴化铅钙钛矿的超快电荷生成和弛豫动力学

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202330

Xiaofan Deng, X. Wen, R. Sheng, Shujuan Huang, T. Harada, Tak W. Kee, M. Green, A. Ho-baillie

引用次数: 1

Sub-wavelength Si-based plasmonic light emitting tunnel junction 亚波长硅基等离子体发光隧道结

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202439

H. Goktas, V. Sorger

引用次数: 0

Evaluation of additive element to improve PZT piezoelectricity by using first-principles calculation 用第一性原理计算评价加性元件对PZT压电性的改善作用

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202407

Yutaka Yasoda, Y. Uetsuji, K. Tsuchiya

{"title":"Evaluation of additive element to improve PZT piezoelectricity by using first-principles calculation","authors":"Yutaka Yasoda, Y. Uetsuji, K. Tsuchiya","doi":"10.1117/12.2202407","DOIUrl":"https://doi.org/10.1117/12.2202407","url":null,"abstract":"Recently, piezoelectric material has a very important potential for functional material which configure Bio-MEMS (Biological Micro Electro Mechanical Systems) actuator and sensor. Specifically, in implementation of piezoelectric material for Bio-MEMS, thin film fabrication by sputtering method is made from the viewpoint of miniaturization. Furthermore, in piezoelectric material, perovskite type material composed of ABO3 has a high piezoelectricity. Then, PZT (Lead Zirconate Titanate) as the perovskite type piezoelectric material is widely used since it is easy to produce and has high piezoelectricity. PZT has zirconium or titanium in the B site of ABO3 structure. PZT has the features such as physical properties to greatly change by change in the B site composition ratio of zirconium and titanium. Thus, the B site greatly influences physical properties and therefore function improvement by additive element is tried widely. However, experimental method to lack in economy and quantitativeness is mainstream. Therefore, application of the result is difficult and new evaluation method of B site additive element for sputtering fabrication is necessary. Accordingly, in this research, search of an additive element at low cost and quantitative from the viewpoint of energy by first-principles calculation. First of all, the additive elements which capable of substituting for a B site of PZT were searched. Next, change of piezoelectricity was evaluated by change of crystal structure in a PZT system was introduced an additive element that substitution of the B site was possible. As a result, additive elements for the PZT B site capable of improving piezoelectricity were determined.","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130278413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A homeostatic, chip-based platform for zebrafish larvae immobilization and long-term imaging 一种用于斑马鱼幼虫固定和长期成像的稳态芯片平台

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202390

Timo Friedrich, F. Zhu, D. Wlodkowic, J. Kaslin

{"title":"A homeostatic, chip-based platform for zebrafish larvae immobilization and long-term imaging","authors":"Timo Friedrich, F. Zhu, D. Wlodkowic, J. Kaslin","doi":"10.1117/12.2202390","DOIUrl":"https://doi.org/10.1117/12.2202390","url":null,"abstract":"Zebrafish larvae are ideal for toxicology and drug screens due to their transparency, small size and similarity to humans on the genetic level. Using modern imaging techniques, cells and tissues can be dynamically visualised and followed over days in multiple zebrafish. Yet continued imaging experiments require specialized conditions such as: moisture and heat control to maintain specimen homeostasis. Chambers that control the environment are generally very expensive and are not always available for all imaging platforms. A highly customizable mounting configuration with built-in means of controlling temperature and media flow would therefore be a valuable tool for long term imaging experiments. Rapid prototyping using 3D printing is particularly suitable as a production method as it offers high flexibility in design, is widely available and allows a high degree of customizing. We study neural regeneration in zebrafish. Regeneration is limited in humans, but zebrafish recover from neural damage within days. Yet, the underlying regenerative mechanisms remain unclear. We developed an agarose based mounting system that holds the embryos in defined positions along removable strips. Homeostasis and temperature control is ensured by channels circulating buffer and heated water. This allows to image up to 120 larvae simultaneously for more than two days. Its flexibility and the low-volume, high larvae ratio will allow screening of small compound libraries. Taken together, we offer a low cost, highly adaptable solution for long term in-vivo imaging.","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128161607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Mid-infrared silicon pillar waveguides 中红外硅柱波导

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202397

Neetesh Singh, D. Hudson, B. Eggleton

引用次数: 0

Controlled deposition of plasma activated coatings on zirconium substrates 等离子体活化涂层在锆基体上的受控沉积

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2202707

B. Akhavan, M. Bilek

引用次数: 4

Relative humidity sensing using dye-doped polymer thin-films on metal substrates 金属基板上染料掺杂聚合物薄膜的相对湿度传感

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2201167

Madhuri Kumari, B. Ding, R. Blaikie

{"title":"Relative humidity sensing using dye-doped polymer thin-films on metal substrates","authors":"Madhuri Kumari, B. Ding, R. Blaikie","doi":"10.1117/12.2201167","DOIUrl":"https://doi.org/10.1117/12.2201167","url":null,"abstract":"We demonstrate humidity sensors based on optical resonances sustained in sub-wavelength thick dye-doped polymer coatings on reflecting surfaces. As a result of coupling between dye molecular absorption and Fabry-Perot resonances in the air-coating-surface cavity, the absorption spectra of such thin-film structures show a strong resonant peak under certain illumination conditions. These resonances are sensitive to the structural and material properties of the thin-film, metal underlayer and ambient conditions and hence can be used for gas and vapor sensing applications. Specifically, we present our proof of principle experimental results for humidity sensing using a thin-film structure comprising Rhodamine6G-doped polyvinyl alcohol (PVA) films on silver substrates. Depending on the PVA film thickness, dye-concertation and angle of incidence, the resonant absorption peak can undergo either red-shift or blue-shift as RH level increases in the range 20% to 60%. Also, the absorption magnitude at certain wavelengths near to resonance show almost linear reduction which can be used as the sensing signal. Our simulation studies show a very good agreement with the experimental data. The spectral and temporal sensitivity of this thin-film structure is attributed to the changes in the thickness of the PVA layer which swells by absorbing water molecules","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124655345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low loss and single mode metal dielectric hybrid-clad waveguides for Terahertz radiation 太赫兹辐射用低损耗单模金属介电混合包覆波导

SPIE Micro + Nano Materials, Devices, and Applications Pub Date : 2015-12-22 DOI: 10.1117/12.2207697

Haisu Li, S. Atakaramians, B. Kuhlmey

{"title":"Low loss and single mode metal dielectric hybrid-clad waveguides for Terahertz radiation","authors":"Haisu Li, S. Atakaramians, B. Kuhlmey","doi":"10.1117/12.2207697","DOIUrl":"https://doi.org/10.1117/12.2207697","url":null,"abstract":"Several waveguide solutions based on technologies from both electronics and photonics have been proposed for guiding Terahertz (THz) radiation. Hollow-core dielectric waveguides are one of the best options for guiding THz radiation since the material absorption is almost zero in the air-core. However, these waveguides are usually multimode and have dimensions in the order of a few millimeters. Here we propose a hollow-core waveguide with sub-wavelength scale metallic wires in the cladding for THz guidance. The theoretical studies show that such a hybrid cladding reflects the transverse magnetic (TM) waves and transmits the transverse electric (TE) waves, leading to a waveguide structure that only confines TM modes. The numerical simulations show a pure single mode, single polarization operation window from 0.22 THz to 0.34 THz and 14.8 dB/m propagation loss at 0.29 THz. Compared to a metallic waveguide with similar dimension, the proposed waveguide more than doubles the single mode operation bandwidth with comparable losses. We discuss the effect of optical and structural parameters of the hybrid cladding on the single mode operating window and propagation losses, and suggest methods of fabrication of the waveguide. The design principle of the proposed waveguide can be extended to the mid-inferred spectrum.","PeriodicalId":320411,"journal":{"name":"SPIE Micro + Nano Materials, Devices, and Applications","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129782512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2