{"title":"[Nephrolithiasis and nephrocalcinosis in children and adolescents].","authors":"Bernd Hoppe, Cristina Martin-Higueras, Nina Younsi, Raimund Stein","doi":"10.1007/s00120-022-01888-3","DOIUrl":"https://doi.org/10.1007/s00120-022-01888-3","url":null,"abstract":"<p><strong>Background: </strong>Nephro- or urolithiasis is a common disease. The prevalence of the disease is increasing in both pediatric and adult patients. The genomic calculation of prevalence may reveal higher levels than the previous diagnosis rates. Monogenic kidney stone disease has been identified in 30% of pediatric and 10% of adult patients.</p><p><strong>Objectives: </strong>Even if it seems legitimate to assume that there is no specific underlying disease in the case of a one-time stone episode, such a disease must be excluded in the pediatric patient. Therefore, the present study discusses in detail the evaluation and treatment of kidney stones in children.</p><p><strong>Methods: </strong>Repeated analysis of 24 h urine samples, or multiple spot urine samples in infants and young children, usually provides evidence of the underlying pathology. In addition, any stone removed should be analyzed. These findings are followed by directed genetic diagnostics. Ultrasonography is the preferred diagnostic method. For symptomatic stones, a minimally invasive method of stone removal is chosen if possible, but not every stone needs to be removed. Family workup must be performed, when a specific diagnosis is made in an index case.</p><p><strong>Conclusion: </strong>Early diagnosis is important to avoid recurrences despite the few treatment options available. Delayed diagnosis can have catastrophic consequences for patients (e.g., renal failure). Standard treatment with hyperhydration and alkali citrate treatment alone often helps prevent recurrences. New therapeutic options give hope that stone diseases will become more treatable. Finally, early diagnosis often avoids problematic courses.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1099-1109"},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40600363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gender-associated differences in bladder cancer].","authors":"Georgios Gakis, Dorothea Weckermann","doi":"10.1007/s00120-022-01914-4","DOIUrl":"https://doi.org/10.1007/s00120-022-01914-4","url":null,"abstract":"<p><strong>Background and objectives: </strong>Although the incidence of bladder cancer among women is lower, they tend to more often have advanced disease at presentation with a more aggressive course. It is still unclear which factors are responsible for the poorer prognosis of bladder cancer in women.</p><p><strong>Materials and methods: </strong>Original papers and reviews from 2004 until 2022 were identified in a PubMed search and evaluated.</p><p><strong>Results: </strong>Multiple factors are likely responsible for the different courses of bladder cancer in women versus men. In the literature, epidemiologic and clinical aspects are discussed. Furthermore, genetic and hormonal causes and the role of the urobiome have been the focus of discussion more recently.</p><p><strong>Conclusions: </strong>Earlier diagnosis and better surgical treatment could lead to a more favorable course of bladder cancer in women. Further analyses of genetic, hormonal, und microbiological factors could open new perspectives in the prevention, diagnosis, and treatment of bladder cancer.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"1060-1067"},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40424199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts des 74. Kongresses der Deutschen Gesellschaft für Urologie e. V.","authors":"","doi":"10.1007/s00120-022-01918-0","DOIUrl":"https://doi.org/10.1007/s00120-022-01918-0","url":null,"abstract":"","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"129-265"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40625199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Selection procedure for scientific contributions to the 2022 DGU Congress].","authors":"Victor Schüttfort","doi":"10.1007/s00120-022-01917-1","DOIUrl":"https://doi.org/10.1007/s00120-022-01917-1","url":null,"abstract":"","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"127-128"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33445365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raisa S Abrams-Pompe, Margit Fisch, Kilian Rödder, Tim Neumann, Philip Reiß, Margarete Hoppe, Andreas W Schneider
{"title":"[Cross-sectoral patient care in the district of Hamburg Harburg: an example of urological cooperation].","authors":"Raisa S Abrams-Pompe, Margit Fisch, Kilian Rödder, Tim Neumann, Philip Reiß, Margarete Hoppe, Andreas W Schneider","doi":"10.1007/s00120-022-01894-5","DOIUrl":"https://doi.org/10.1007/s00120-022-01894-5","url":null,"abstract":"<p><strong>Background: </strong>Ensuring future urological care at the interface between out- and inpatient care is challenging due to demographic developments with an increasing proportion of urological diseases, the simultaneous threat of a shortage of physicians, and the increasing outpatient treatment of complex urological diseases.</p><p><strong>Objectives: </strong>The cross-sectoral cooperation model between a university maximum care provider and the urologic joint practice with a hospital affiliation (BAG) presented below can serve as an ideal model for outpatient-inpatient care.</p><p><strong>Materials and methods: </strong>Since 2016, there has been close cooperation between the BAG in Winsen/Buchholz and the University Medical Center Hamburg-Eppendorf (UKE). In addition to direct patient transfer and the continuous pre- and posttreatment of patients, two residents from the UKE rotate to the BAG every year.</p><p><strong>Results: </strong>The BAG benefits from this cooperation through planning security and support in everyday patient care, while the UKE benefits from patient transfer as well as surgical and \"basic urological\" training of residents. By avoiding duplicate examinations and earlier discharge of patients into outpatient follow-up care, resources are spared. Meaningful patient preselection enables minor interventions to be performed close to home via the BAG, whereas complex cases are carried out at a center of excellence.</p><p><strong>Conclusions: </strong>The cooperation is seen positively by all parties without exception and, above all, as a benefit for the patient's wellbeing. The optimal training and further education of young urologists in this expanding field can thus be supported and should be integrated into urological resident training.</p>","PeriodicalId":319655,"journal":{"name":"Urologie (Heidelberg, Germany)","volume":" ","pages":"939-947"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40600364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}