{"title":"Subband spectral complexity distance for cortical health evaluation and monitoring in ischemic brain injury","authors":"R. Gharieb, M. Hathi, N. Thakor","doi":"10.1109/CIBEC.2010.5716092","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716092","url":null,"abstract":"A quantitative electroencephalogram (qEEG) index for the evaluation and monitoring of cortical health in ischemic brain injury is presented. The proposed qEEG index, called the subbands spectral complexity distance (SSCD), measures the distance between a vector of subbands spectral complexities computed from the investigated EEG and a one computed from normal EEG. For the computation of the SSCD, the spontaneous power spectral density of the EEG signal is estimated using the time-varying autoregressive (TV-AR) model, decomposed into subbands and the spectral complexity of each subband is computed. Results of evaluating human EEG data are presented to show the usefulness of the proposed SSCD index. It is shown that the index increases during the time-segments of ischemic brain injury while decreases during the normal and recovery segments. This can be explained by the fact that the ischemic brain injury may increase the irregularity of the EEG signal and therefore the power spectral density becomes more complex with ischemic brain injury.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130644416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decision Support Systems in clinical engineering","authors":"A. A. Kamel, Bassel S. Tawfik","doi":"10.1109/CIBEC.2010.5716074","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716074","url":null,"abstract":"Decision Support Systems (DSS) are very important in clinical engineering (CE). The Analytic Hierarchy Process (AHP) is one of such systems that has been extensively and successfully used in many areas, including CE. In this paper, we provide an overview of different DSS and explain AHP in details. At the end, a case study using AHP for taking medical equipment scrapping/ retirement decision is presented.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132267847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Acierno, S. D. Pascali, Francesco P. Fanizzi, M. Maffia, L. Mainetti, L. Patrono, E. Urso
{"title":"Investigating potential effects of RFID systems on the molecular structure of the human insulin","authors":"R. Acierno, S. D. Pascali, Francesco P. Fanizzi, M. Maffia, L. Mainetti, L. Patrono, E. Urso","doi":"10.1109/CIBEC.2010.5716055","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716055","url":null,"abstract":"The Radio Frequency Identification (RFID) is a wireless technology that is becoming more and more important as auto-identification solution for many application scenarios. The adoption of this innovative technology in the pharmaceutical sector promises to solve several problems related to tracing and tracking systems at item level. Unfortunately, there are still some barriers limiting the largescale deployment of RFID technologies. One of these is related to very interesting research topics on the evaluation of potential effects of electromagnetic fields on drugs. In detail, this work aimed to analyze the impact of UHF RFID devices, used in tracing systems, on the molecular structure and potency of a commercial human insulin preparation, ActrapidTM. In order to investigate possible induced alterations of molecular structure, the Reverse Phase-High Pressure Liquid Chromatography and the Nuclear Magnetic Resonance spectroscopy have been mainly used in the experimental protocol. To obtain some indications about drug performance, in vitro cell proliferation assays have been also conducted. The experimental results, achieved by a protocol combining an accurate structural analysis on 5 min to 24 h irradiated drug samples with functional in vitro assays, have shown that the electromagnetic field generated by UHF RFID devices does not cause significant effects on ActrapidTM insulin. These findings are strongly encouraging the use of RFID-based technologies for item-level tracing systems in the pharmaceutical supply chain.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122332692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanie P. Ware, P. Mccullagh, A. McRoberts, G. Lightbody, C. Nugent, Gerry McAllister, M. Mulvenna, Eileen Thomson, Suzanne Martin
{"title":"Contrasting levels of accuracy in command interaction sequences for a domestic brain-computer interface using SSVEP","authors":"Melanie P. Ware, P. Mccullagh, A. McRoberts, G. Lightbody, C. Nugent, Gerry McAllister, M. Mulvenna, Eileen Thomson, Suzanne Martin","doi":"10.1109/CIBEC.2010.5716040","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716040","url":null,"abstract":"Providing a usable domestic brain-computer interface (BCI) for persons with disabilities requires that the development team ensure ease of interaction for all the potential users. To do this for individuals with complex needs often requires that an approach is tailored to a specific user. However, in developing a domestic BCI it is necessary to consider the provision of an application which hides the complexity of the underlying science from the user whilst delivering acceptable levels of interaction for many. This is not an unusual circumstance in the realm of assistive technology. We present a cohesive test suite which allows the development team to assess what constitutes an acceptable level of accuracy in a four-way command interface using steady-state visually evoked potentials (SSVEP). It also facilitates a uniform assessment of the level of accuracy achieved by a specific user operating a BCI and provides a means of contrasting and selecting performance parameters in order to enhance user performance.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114066034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiscale principal component analysis to denoise multichannel ECG signals","authors":"L. Sharma, S. Dandapat, A. Mahanta","doi":"10.1109/CIBEC.2010.5716093","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716093","url":null,"abstract":"In this work, multiscale principal component analysis (MSPCA) is introduced for denoising of multichannel electrocardiogram (MECG) signals. Wavelet decomposition of MECG signals segments the clinical information content at different Wavelet subbands or scales. At subband levels or scales multivariate data matrix are formed using Wavelet coefficients extracted from the same scales of MECG signals. At each subband matrix or scales, PCA is applied for noise elimination. To retain essential diagnostic components, matrices comprising of lower order Wavelet subbands are processed with reduced set of principal component (PC). Qualitative performance is evaluated and quantitative performance of denoising effect is measured by input/output signal-to-noise ratio (SNR). Signal distortion measures are evaluated using percentage root mean square difference (PRD), Wavelet weighted PRD (WWPRD) andWavelet energy based diagnostic distortion measure (WEDD). The proposed algorithm is tested with database of CSE multilead measurement library. The results show significant improvement in denoising of MECG signals with the lowest PRD of 3.488 and high SNR improvement of 34.279 dB.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131880051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Noise and the detection of coronary artery disease with an electronic stethoscope","authors":"S. Schmidt, E. Toft, C. Holst-Hansen, J. Struijk","doi":"10.1109/CIBEC.2010.5716077","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716077","url":null,"abstract":"Recent studies demonstrated that diastolic heart sounds, recorded with an electronic stethoscope, contain markers of coronary artery disease (CAD). A difficult is that the CAD-related sound is very weak and recordings are often contaminated by noise. The current study analyses the noise contamination of 633 stethoscope recordings from a clinical environment. Respiration noise, ambient noise, recording noise and abdominal noise were identified in the recordings and were classified according to duration and intensity. To monitor how noise influences the classification performance AR-pole magnitudes were extracted from both the 25–250 Hz frequency band and the 250–1000 Hz frequency band. The classification performance was quantified by the Area Under the receiver operating Characteristic (AUC). Ambient noise was present in 39.9% of the recordings and was the most common noise source. Abdominal noise was the least common noise source, present in 10.8% of the recordings. The best pole, with respect to detection of CAD, extracted from the 250–1000 Hz frequency band was sensitive to noise, since the AUC dropped from 0.70 in to 0.57 when noisy recordings were included. Contrary the best pole from the 25–250 Hz frequency band was relatively robust against noise, since the AUC dropped from 0.73 to only 0.70 when noisy recordings were included. The study demonstrated that noise contamination is a frequent problem and that features from lower frequency bands are more robust against noise than features from higher frequency bands.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128957371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of sensor configurations on indirect-contact photoplethysmogram measurement system","authors":"H. Baek, S. Sim, Jung Soo Kim, K. Park","doi":"10.1109/CIBEC.2010.5716070","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716070","url":null,"abstract":"Indirect-contact photoplethysmography is a new approach to measure photoplethysmogrm over clothing for unconstrained and unconscious monitoring purpose. In this paper, the effect of sensor configurations on indirect-contact photoplehysmography was investigated. Sensor configuration was classified into two groups. One was multiple light sources with centered photo-detector configuration and the other was multiple photo-detectors with centered light source configuration. Total 8 kinds of sensors were tested. Experimental results showed that although both sensor groups have possibility to photoplethysmogram measurement over clothing, sensors with multiple light sources showed better performance when thick clothes were considered. Sensor configuration should be selected with regard to its application considerations such as power consumption or target subjects.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123397262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A compression-based technique for comparing biological sequences","authors":"Ramezani Mina, Hesham H. Ali","doi":"10.1109/CIBEC.2010.5716047","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716047","url":null,"abstract":"Comparing biological sequences represents one of the most important tools in computational biology. By comparing the sequences, we identify similar subsequences which may lead to the identification of structures as well as similar functions. Sequence alignment has been the method of choice for testing similarity and gained a lot of trust among researchers, though this method suffers some shortcomings. In particular, having repetitions in the input sequences often leads to inaccurate results, especially if these repetitions are dispersed overall the sequence. In this paper, we are conducting a study of alternative methods based on compression techniques, borrowed from information theory, to identify accurate comparison of the sequences. We test the proposed technique on various datasets and illustrate that they outperform alignment based methods in several cases.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123739240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the validation of gene expression clusters","authors":"N. A. Yousri","doi":"10.1109/CIBEC.2010.5716091","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716091","url":null,"abstract":"Classical validity indices are limited to clusters of specific geometrical shapes, and do not allow for discovering the natural cluster structure in data. Moving from the traditional coherent gene expression clustering to exploring the connectivity of gene expression patterns demands the use of more efficient validity indices. In this work, the application of a novel validity measure to gene expression clustering is investigated. The measure was previously introduced by the author to evaluate clusters of arbitrary shapes in low and high dimensional data. However, experimenting with its applicability to gene expression data is the main focus of the presented work. Leukaemia and breast cancer sets are used to evaluate the applicability of the proposed validity to discover the natural connectedness of expression patterns.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115269924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parallel suffix sorting based on bucket pointer refinement","authors":"Hisham Mohamed, M. Abouelhoda","doi":"10.1109/CIBEC.2010.5716066","DOIUrl":"https://doi.org/10.1109/CIBEC.2010.5716066","url":null,"abstract":"Suffix array is one of the most important data structures in bioinformatics. Much effort has been devoted to find efficient sequential algorithms for its construction, but little is done to introduce parallel construction algorithms. The bucket pointer refinement algorithm is one of the efficient suffix sorting algorithms that is tuned for genomic datasets. In this paper, we introduce a parallel version of this algorithm running on (shared memory) multicore computers. We present experimental results comparing our algorithms to other parallel algorithms running on similar architecture. Our program is open source and available at http://www.nubios.nileu. edu.eg/tools/pbpr.","PeriodicalId":319141,"journal":{"name":"2010 5th Cairo International Biomedical Engineering Conference","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114912063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}