International Journal of Reproductive BioMedicine (IJRM)最新文献_第2页

The effect of Henna (Lawsonia inermis) vaginal suppository combined with antibiotic therapy in the treatment of cervicitis: An RCT Henna（Lawsonia inermis）阴道栓剂联合抗生素治疗宫颈炎的效果：一项 RCT 研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-06-08 DOI: 10.18502/ijrm.v22i4.16388

Naeeme Nabimeybodi, Fahimeh Nokhostin, R. Zareshahi, Mohammad Kamalinejad, Hedayat Akhundimeybodi, F. Madadizadeh, Mohsen Nabi Meybodi, Narges Seifi Mazraeno, Razieh Nabimeybodi

{"title":"The effect of Henna (Lawsonia inermis) vaginal suppository combined with antibiotic therapy in the treatment of cervicitis: An RCT","authors":"Naeeme Nabimeybodi, Fahimeh Nokhostin, R. Zareshahi, Mohammad Kamalinejad, Hedayat Akhundimeybodi, F. Madadizadeh, Mohsen Nabi Meybodi, Narges Seifi Mazraeno, Razieh Nabimeybodi","doi":"10.18502/ijrm.v22i4.16388","DOIUrl":"https://doi.org/10.18502/ijrm.v22i4.16388","url":null,"abstract":"Background: Cervicitis is a prevalent gynecologic disease, which does not usually respond to conventional treatments. Long-term cervicitis can cause serious health problems such as inflammation, infertility, and cancer. Henna oil, an herbal product in Persian medicine, is recommended for uterine diseases like cervicitis. \u0000Objective: This study aims to evaluate the efficacy of Henna oil as a vaginal suppository in combination with an antibiotic regimen in the treatment of cervicitis. \u0000Materials and Methods: This randomized placebo-controlled trial, included 92 nonmenopausal women with cervicitis at the Baqaipur Clinic of Shahid Sadoughi hospital in Yazd and the Persian Medicine Health Center in Ardakan, Yazd, Iran. Participants were further divided into either the Henna oil vaginal suppository group or the placebo group (n = 46/each group). During the study, the antibiotic treatment was administered to both groups. Cervicitis symptoms were compared between the groups and within each group. Results: Of 92 included individuals, 41 in each group completed the study. \u0000Results: revealed that significant differences were observed in some outcomes, including vaginal discharge (p < 0.001), cervical ulcer size (p < 0.001), dyspareunia (p = 0.046), and postcoital bleeding (p < 0.001), indicating that the treatment was more effective in the henna group compared to the placebo group. \u0000Conclusion: Findings supported that the vaginal suppository of Henna oil in combination with antibiotic therapy could be effective in the improvement of clinical symptoms of cervicitis regardless of its pathology. \u0000Key words: Lawsonia inermis, Persian+traditional medicine, Uterine cervicitis, Infertility, Vaginal suppository, Clinical trial.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of serum levels of interleukin 33 in combination with serum levels of C-reactive protein, Immunoglobulin G, Immunoglobulin A, and Immunoglobulin M in recurrent pregnancy loss: A case-control study 比较白细胞介素 33 血清水平与 C 反应蛋白、免疫球蛋白 G、免疫球蛋白 A 和免疫球蛋白 M 血清水平在复发性妊娠失败中的组合：病例对照研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-06-08 DOI: 10.18502/ijrm.v22i4.16392

Hossein Ali Khazaei, Farahnaz Farzaneh, Saeedeh Sarhadi, J. Haghighi, Forough Forghani, Vahid Sheikhi, B. Khazaei, Lida Asadollahi

{"title":"Comparison of serum levels of interleukin 33 in combination with serum levels of C-reactive protein, Immunoglobulin G, Immunoglobulin A, and Immunoglobulin M in recurrent pregnancy loss: A case-control study","authors":"Hossein Ali Khazaei, Farahnaz Farzaneh, Saeedeh Sarhadi, J. Haghighi, Forough Forghani, Vahid Sheikhi, B. Khazaei, Lida Asadollahi","doi":"10.18502/ijrm.v22i4.16392","DOIUrl":"https://doi.org/10.18502/ijrm.v22i4.16392","url":null,"abstract":"Background: One of the critical cases of recurrent pregnancy loss is immunological factors, whereas obtaining effective prevention or treatment is necessary for cognition of reasons. Objective: In this study, we tried to evaluate some immunological factors related to recurrent pregnancy loss. \u0000Materials and Methods: This case-control study was conducted on 66 women at the age of 18–35 yr who were referred to the Clinic of Gynecology and Obstetrics, Ali Ibn Abi Taleb hospital, Zahedan, Iran, from August-December 2019. Interleukin 33 (IL-33) serum levels were measured using enzyme-linked immunosorbent assay. Immunoglobulin G, Immunoglobulin A, Immunoglobulin M (IgM), and C-reactive protein levels were measured by serology and hematology methods. \u0000Results: The mean age of total participants was 30.8 ± 3.80 yr. The mean serum IL-33 in the case group was 318.5± 254.1 pg/ml and was lower than the control group (354.2± 259.9 pg/ml), which was not statistically significant (p = 0.52). The level of C-reactive protein in the case and control was not significantly different (p = 0.27), and Immunoglobulin A and Immunoglobulin G in the case and control were also not significantly different) p = 0.46, and p = 0.16, respectively), but there were significant differences (p= 0.003) between the level of the IgM in the case and control groups. \u0000Conclusion: No statistically significant difference was observed in the IL-33 serum level, for at least 4–6 months after the last abortion in the case group and the final live birth in the control group. In contrast, serum levels of IgM were statistically significant. Finally, the need for more studies is felt according to the different results of the previous studies in this field. \u0000Key words: Interleukin-33, Abortion, IgG, IgA, IgM.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The report of ovarian tissue transplant in Iran: A case report 伊朗卵巢组织移植报告：病例报告

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-06-08 DOI: 10.18502/ijrm.v22i4.16393

F. Anbari, Mohammad Ali Khalili, M. Vatanparast, Saeid Haghdani, Maryam Eftekhar

{"title":"The report of ovarian tissue transplant in Iran: A case report","authors":"F. Anbari, Mohammad Ali Khalili, M. Vatanparast, Saeid Haghdani, Maryam Eftekhar","doi":"10.18502/ijrm.v22i4.16393","DOIUrl":"https://doi.org/10.18502/ijrm.v22i4.16393","url":null,"abstract":"Background: Cancer treatments such as chemotherapy and radiotherapy increase the chance of ovarian failure. Ovarian tissue transplantation (OTT) is a viable option for fertility preservation in these cases. We aim to report ovarian transplantation in a leukemia case undergoing the vitrification method. \u0000Case Presentation: The case was a 28-yr-old female in Research and Clinical Center for Infertility, Yazd, Iran who was suffering from leukemia. Ovarian biopsy was performed by laparoscopy surgery and transported to cryopreservation lab at 4°C for 1–2 hr. The ovarian cortex was removed from the medulla, and ovarian strips were cryopreserved by vitrification. This procedure used the equilibration and vitrification solutions including medium 199 supplemented with 20% serum, and ethylene glycol and dimethyl sulfoxide with concentrations of 7.5% and 20%, respectively. Before doing OTT, we assessed the tissue viability and follicular count by chick embryo chorioallantoic membranes and histologic survey, respectively. OTT was done after complete remission, following warmed tissue sutured together and transplanted on the residual medulla on the right side. On the left side, the ovary was removed completely; however, 2 strips were put on the peritoneal pocket. Anti-Müllerian hormone, follicle-stimulating hormone, and luteinizing hormone levels were 0.1 ng/mL, 36.5 mIU/mL, and 19.8 mIU/mL before OTT. During a 6-month follow-up, the anti-Müllerian hormone increased to 0.9, and then follicle-stimulating hormone and luteinizing hormone levels decreased dramatically until 17.47 mIU/mL and 6.71 mIU/mL, respectively. Also, the patient had 3 cycles of menstrual periods. \u0000Conclusion: We demonstrated an appropriate hormonal profile, and the restoration of the menstrual cycle might indicate a successful transplant. Further investigations are needed to achieve successful clinical outcomes. \u0000Key words: Cryopreservation, Tissue transplantation, Leukemia, Vitrification, Ovarian follicle.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141369174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in menstrual cycles among Iranian women during the COVID-19 pandemic: A cross-sectional study COVID-19 大流行期间伊朗妇女月经周期的变化：横断面研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-06-08 DOI: 10.18502/ijrm.v22i4.16389

F. Ranjbar, S. Haghani, Motahareh Aghashahi, M. Gharacheh

{"title":"Changes in menstrual cycles among Iranian women during the COVID-19 pandemic: A cross-sectional study","authors":"F. Ranjbar, S. Haghani, Motahareh Aghashahi, M. Gharacheh","doi":"10.18502/ijrm.v22i4.16389","DOIUrl":"https://doi.org/10.18502/ijrm.v22i4.16389","url":null,"abstract":"Background: Some women experienced alterations in their menstrual cycles during the Coronavirus disease 2019 (COVID-19) pandemic. \u0000Objective: This study aimed to evaluate the changes in menstrual cycles among Iranian women during the COVID-19 pandemic. \u0000Materials and Methods: This cross-sectional study included 1500 women of childbearing age referred to healthcare centers in Tehran, Iran from April-November 2022. Participants were selected using the stratified sampling method. Data were collected via a questionnaire covering information on menstrual cycle, COVID- 19 infection, and COVID-19 vaccination status. The study’s outcomes focused on menstrual changes by evaluating cycle regularity, duration, and symptoms based on participant-reported observations. \u0000Results: The findings revealed that the pattern of menstrual change during the pandemic occurred in the form of a shorter interval in 8.6%, and longer interval in 8.9%, shorter duration in 10.4%, longer duration in 9.4%, heavier bleeding in 12.3%, lighter bleeding in 14.7%. The chance of menstrual changes in women who were infected with COVID-19 was 54% higher than that of women who were not infected, and the chance of menstrual changes in women who received 3 doses of COVID-19 vaccine was 1.5 times higher than women who had not been vaccinated. \u0000Conclusion: Our research revealed a high incidence of menstrual changes among Iranian women of childbearing age during the COVID-19 pandemic. Healthcare providers should be knowledgeable about the menstrual changes associated with COVID-19 infection and vaccination to provide information and support to affected women. \u0000Key words: Menstrual cycle, Menstrual irregularities, COVID-19, Vaccine.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141369507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letrozole and ovarian hyperstimulation syndrome: Retrospective cross-sectional study 来曲唑与卵巢过度刺激综合征：回顾性横断面研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16165

Elham Nikfarjam, Maryam Eftekhar, Hanieh Fatehi, Sahereh Arabian

{"title":"Letrozole and ovarian hyperstimulation syndrome: Retrospective cross-sectional study","authors":"Elham Nikfarjam, Maryam Eftekhar, Hanieh Fatehi, Sahereh Arabian","doi":"10.18502/ijrm.v22i3.16165","DOIUrl":"https://doi.org/10.18502/ijrm.v22i3.16165","url":null,"abstract":"Background: Recently, letrozole has been used to prevent moderate to severe ovarian hyperstimulation syndrome (OHSS) in assisted reproductive technology cycles due to its estrogen-reducing and androgen-increasing effects on the ovaries, affecting granulosa cells, and reducing vascular endothelial growth factor production. \u0000Objective: This study aimed to investigate the impact of letrozole consumption in preventing OHSS in infertile women with polycystic ovarian syndrome undergoing in vitro fertilization. \u0000Materials and Methods: In this cross-sectional study, among 1743 medical records of infertile women who were scheduled for oocyte retrieval at Research and Clinical Center for Infertility, Yazd, Iran. Data of 343 women with polycystic ovarian syndrome diagnosis and at risk of OHSS was extracted from March 2022–2023. The stimulation was carried out using a flexible gonadotropin releasing hormone (GnRH) antagonist protocol. Women were divided into 2 groups based on whether they received letrozole or not. In the letrozole group, 2.5 mg letrozole twice daily was continued from the trigger day, while in the control group, women did not receive letrozole. The parameters of OHSS severity, hospitalization rates, and the need for albumin prescription were analyzed. \u0000Results: 89 women in the letrozole and 254 women in the control group were examined. There was no statistically significant difference between groups in terms of age and body mass index; however, anti-Mullerian hormone was significantly higher than control group (7.53 ± 4.61 vs. 5.47 ± 3.63, p < 0.001). The parameters of OHSS severity, hospitalization rates, and the need for albumin prescription showed no significant differences between the groups. \u0000Conclusion: Recent study indicates that incorporating letrozole into the treatment of GnRH antagonists and cabergoline does not reduce the OHSS severity. \u0000Key words: Letrozole, Polycystic ovary syndrome, Ovarian hyperstimulation syndrome, Assisted reproductive technologies.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":"114 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Naringenin ameliorates cytotoxic effects of bisphenol A on mouse Sertoli cells by suppressing oxidative stress and modulating mitophagy: An experimental study 柚皮苷通过抑制氧化应激和调节有丝分裂来改善双酚 A 对小鼠 Sertoli 细胞的细胞毒性作用：一项实验研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16166

Layasadat Khorsandi, Abbas Heidari-Moghadam, Elham Younesi, Mohammad-Javad Khodayar, Yousef Asadi-Fard

{"title":"Naringenin ameliorates cytotoxic effects of bisphenol A on mouse Sertoli cells by suppressing oxidative stress and modulating mitophagy: An experimental study","authors":"Layasadat Khorsandi, Abbas Heidari-Moghadam, Elham Younesi, Mohammad-Javad Khodayar, Yousef Asadi-Fard","doi":"10.18502/ijrm.v22i3.16166","DOIUrl":"https://doi.org/10.18502/ijrm.v22i3.16166","url":null,"abstract":"Background: Bisphenol A (BPA), an endocrine-disrupting agent, is widely used as polycarbonate plastics for producing food containers. BPA exposure at environmentally relevant concentrations can cause reproductive disorders. \u0000Objective: The effect of Naringenin (NG) on BPA-induced Sertoli cell toxicity and its mechanism was examined in the present study. \u0000Materials and Methods: In this experimental-laboratory study, the mouse TM4 cells were treated to BPA (0.8 μm) or NG for 24 hr at concentrations of 10, 20, and 50 μg/ml. Cell viability, reactive oxygen species (ROS) production, malondialdehyde (MDA) content, antioxidant level, and mitochondrial membrane potential (MMP) were examined. The expression of mitophagy-related genes, including Parkin and PTEN-induced putative kinase 1 (Pink1), was also evaluated. \u0000Results: BPA significantly lowered the viability of the Sertoli cells (p = 0.004). Pink1 and Parkin levels of the BPA group were significantly increased (p < 0.001), while the MMP was considerably decreased (p < 0.001). BPA raised MDA and ROS levels (p < 0.001) and reduced antioxidant biomarkers (p = 0.003). NG at the 20 and 50 μg/ml concentrations could significantly improve the viability and MMP of TM4 cells (p = 0.034). NG depending on concentration, could decrease Pink1 and Parkin at mRNA and protein levels compared to the BPA group (p = 0.024). NG enhanced antioxidant factors, while ROS and MDA levels were decreased in the BPA-exposed cells. \u0000Conclusion: The beneficial impacts of NG on BPA-exposed Sertoli cells are related to the suppression of mitophagy and the reduction of oxidative stress. \u0000Key words: Mitophagy, Naringenin, Sertoli cells, Bisphenol A, Reactive oxygen species, Pink1, Parkin.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":"103 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140987243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The categorization of opaque pathologies outside of contrast media in hysterosalpingography which facilitate interpretation: A pictorial review 子宫输卵管造影中造影剂外不透明病变的分类有助于判读：图解回顾

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16163

Fereshteh Hosseini, Fattaneh Pahlavan, Firoozeh Ahmadi

{"title":"The categorization of opaque pathologies outside of contrast media in hysterosalpingography which facilitate interpretation: A pictorial review","authors":"Fereshteh Hosseini, Fattaneh Pahlavan, Firoozeh Ahmadi","doi":"10.18502/ijrm.v22i3.16163","DOIUrl":"https://doi.org/10.18502/ijrm.v22i3.16163","url":null,"abstract":"Hysterosalpingography (HSG) is a practical and reliable imaging method to evaluate the cervical canal, uterine isthmus, uterine cavity, and fallopian tubes. Using HSG, opaque pathologies outside of contrast media can be detected as well as pathologies of uterus and fallopian tubes. We aim to present and categorize some uncommon and interesting abnormal findings that are located outside of the contrast areas in HSG. This is a pictorial review that depicts various types of HSG images that include opaque pathologies outside of the contrast areas. Images have been extracted from valuable archives collected over 50 yr by professor Shahrzad. A plain pelvic film contains soft tissues of the pelvis, bony structures, artifacts, or foreign bodies. Categorization might easily help the radiologist to interpret the HSG cliché. Opaque pathologies outside of contrast area in HSG can be categorized into 2 groups: “Pelvic Tissue Related” and “Foreign Bodies”. Pelvic tissue abnormalities might have a gynecologic or nongynecologic source. Foreign bodies can be located in the pelvis or outside of the body. HSG is a reliable and inexpensive procedure. Familiarity with the pathologies of pelvic tissues and the accurate interpretation of HSG images are important. \u0000Key words: Hysterosalpingography, Opaque, Abnormalities, Uterine, Fallopian tubes.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":"115 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of the course of severe and critical COVID-19 in pregnant women: A prospective cross-sectional study 孕妇严重和危重 COVID-19 病程的特征：前瞻性横断面研究

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16167

Shaimerdenova Gulbanu Ganikyzy, Gulzhan Narkenovna Abuova, Saltanat Kulbayeva Nalibekkyzy

{"title":"Features of the course of severe and critical COVID-19 in pregnant women: A prospective cross-sectional study","authors":"Shaimerdenova Gulbanu Ganikyzy, Gulzhan Narkenovna Abuova, Saltanat Kulbayeva Nalibekkyzy","doi":"10.18502/ijrm.v22i3.16167","DOIUrl":"https://doi.org/10.18502/ijrm.v22i3.16167","url":null,"abstract":"Background: At the beginning of the Coronavirus disease 2019 (COVID-19) pandemic, studies showed that the risk of severe disease was higher in pregnant women. \u0000Objective: This study investigates the characteristics of severe and critical types of COVID-19 coronavirus infection in pregnant women. \u0000Materials and Methods: This prospective cross-sectional study compared the medical records of 120 pregnant women with severe and very severe COVID-19 treated at the Infectious Disease Center, Shymkent, Kazakhstan from December 2021 to May 2022. Factors such as time of hospital admission, hospitalization period, maternal comorbidities, age, pregnancy and postpartum complications, pregnancy outcomes, and treatment type were analyzed. \u0000Results: 87 (72.5%) pregnant women with severe and 33 (27.5%) with critical type of COVID-19 were included. The following data were obtained when comparing the pregnancy parity of the subjects, depending on the gestational age: in 1–12 wk, the indicator was 3.75 ± 0.95; in 13–27 wk3.00 (Q1-Q3: 2.00–4.00), in 28–40 wk 3.00 (Q1-Q3: 2.00–4.00). Severe COVID-19 coronavirus infection occurs in women with more than a third pregnancy (Me 3.00 [Q1-Q3: 2.00–4.00]). \u0000Conclusion: There is a risk of disease progression to severe and critical COVID-19 in pregnant women older than 33 yr of age and at 28–40 wk gestation. Early referral to a doctor in hospital, timely hospitalization, and initiated treatment reduces the risk of aggravation of the patient’s condition and development of formidable complications. \u0000Key words: COVID-19, Pregnancy, Infection.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":"116 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “The effect of topical endometrial scratching on pregnancy outcome in women with previous failure of intrauterine insemination: A non-randomized clinical trial” [Int J Reprod BioMed 2021; 19: 465-470] 对 "局部子宫内膜搔刮对既往宫腔内人工授精失败妇女妊娠结果的影响：一项非随机临床试验" [Int J Reprod BioMed 2021; 19: 465-470] 的更正

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16169

Farahnaz Farzaneh, Farzaneh Khastehfekr

引用次数: 0

Comparing the advantages, disadvantages and diagnostic power of different non-invasive pre-implantation genetic testing: A literature review 比较不同无创性植入前基因检测的优缺点和诊断能力：文献综述

International Journal of Reproductive BioMedicine (IJRM) Pub Date : 2024-05-12 DOI: 10.18502/ijrm.v22i3.16161

N. Karami, Farzaneh Iravani, Sareh Bakhshandeh Bavarsad, Samira Asadollahi, Seyed Mehdi Hoseini, Fateme Montazeri, S. Kalantar

{"title":"Comparing the advantages, disadvantages and diagnostic power of different non-invasive pre-implantation genetic testing: A literature review","authors":"N. Karami, Farzaneh Iravani, Sareh Bakhshandeh Bavarsad, Samira Asadollahi, Seyed Mehdi Hoseini, Fateme Montazeri, S. Kalantar","doi":"10.18502/ijrm.v22i3.16161","DOIUrl":"https://doi.org/10.18502/ijrm.v22i3.16161","url":null,"abstract":"To improve embryo transfer success and increase the chances of live birth in assisted reproductive methods, there is a growing demand for the use of pre-implantation genetic testing (PGT). However, the invasive approaches used in PGT have led to in vitro fertilization failure and abortions, increasing anxiety levels for parents. To address this, non-invasive PGT methods have been introduced, such as the detection of DNA in blastocoel fluid of blastocysts and spent culture media (SCM). These methods have proven to be minimally invasive and effective in detecting aneuploidy in the chromosomes of human embryos. This review aims to explore the different approaches to pre-implantation diagnosis, including invasive and non-invasive methods, with a particular focus on non-invasive PGT (niPGT). The search strategy involved gathering data from scientific databases such as PubMed, Google Scholar, and Science Direct using relevant keywords. The search was conducted until January 2023. In total, 22 studies have successfully reported the detection and amplification of cell-free DNA in the embryonic SCM. It is important to note that niPGT has some limitations, which include differences in indicators such as cell-free DNA amplification rate, concordance, level of maternal DNA contamination, sensitivity, and specificity between SCM samples and biopsied cells. Therefore, more extensive and detailed research is needed to fully understand niPGT’s potential for clinical applications. \u0000Key words: Spent culture media, Non-invasive pre-implantation genetic testing, Biopsy methods, Cell-free embryonic DNA.","PeriodicalId":318611,"journal":{"name":"International Journal of Reproductive BioMedicine (IJRM)","volume":"120 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0