Journal of King Abdulaziz University - Medical Sciences最新文献

Frequency of Red Blood Cells Alloimmunization in Thalassemia Patients at King Abdulaziz University Hospital in Jeddah, Saudi Arabia 沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院地中海贫血患者红细胞同种免疫频率

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-12-31 DOI: 10.4197/med.26-2.1

Salwa A. Alnajjar, T. Tayeb, Abdulrahman S. Alboog, Tarek Elgemmezi, S. Hindawi

{"title":"Frequency of Red Blood Cells Alloimmunization in Thalassemia Patients at King Abdulaziz University Hospital in Jeddah, Saudi Arabia","authors":"Salwa A. Alnajjar, T. Tayeb, Abdulrahman S. Alboog, Tarek Elgemmezi, S. Hindawi","doi":"10.4197/med.26-2.1","DOIUrl":"https://doi.org/10.4197/med.26-2.1","url":null,"abstract":"The aim of the study is to assess the alloimmunization rate to red blood cell in thalassemia patients at King Abdulaziz University Hospital. Thalassemia is the most common genetic disorder worldwide that represents a major public health problem and requires long life blood transfusion to the patients as the main treatment. Alloimmunization to the transfused red blood cell can cause hemolytic transfusion reactions and significantly complicate transfusion therapy. Screening and identification of alloantibodies and transfusion of extended phenotyped blood can minimize these risks. A retrospective study was conducted on 134 thalassemia patients at King Abdulaziz University Hospital in Jeddah. Patients’ samples were subjected to red cell typing, antibody screening and identifi cation of red blood cell antibodies. Alloimmunization in thalassemia patients was 20.15%; antibodies were mainly to the Rh and Kell blood group systems, the highest rate was for anti-E (32.4%) followed by anti-K (21.6%). Alloimmunization rate was the highest in the age group from > 10 – 20 years (40.7%). Red cell alloimmunization is a frequent event among thalassemia patient. A national protocol for screening and identifying of the red cell alloantibodies and transfusion of phenotype blood is required for proper management of these patients.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"13 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124353667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

An Audit on Compliance of Surgical Time Out after a Decade of Implementation at an Academic Tertiary Care Hospital 某三级专科医院实施手术暂停十年后的依从性审计

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.4

T. Al-Khatib, A. Mirza, Manar A. Malakah, Afnan E Jiffri, Lujain K. Abdalwassie, Dina M. Hijazi

{"title":"An Audit on Compliance of Surgical Time Out after a Decade of Implementation at an Academic Tertiary Care Hospital","authors":"T. Al-Khatib, A. Mirza, Manar A. Malakah, Afnan E Jiffri, Lujain K. Abdalwassie, Dina M. Hijazi","doi":"10.4197/med.26-1.4","DOIUrl":"https://doi.org/10.4197/med.26-1.4","url":null,"abstract":"A surgical safety checklist is essential to ensure patient safety. The purpose of this study was to evaluate the implementation of surgical time-out at an academic medical center in Saudi Arabia, and to reveal potential factors that may influence the compliance of time-out. A cross-sectional study observing elective surgeries was performed at King Abdulaziz University Hospital. Sixteen operating theaters were screened, corresponding to 15 different specialties being examined. Overall, one hundred and sixteen elective procedures were observed. The time-out checklist was employed by staff in 45.7% of cases and was fully completed in 26.7%. Factors influencing the time-out adherence included overall staff presence and the involvement of the primary surgeon during the time-out phase (p < 0.001). Absence of some staff members was significantly associated with a higher rate of time-out noncompliance (OR = 0.04; 95%; CI = 0.01, 0.21; p < 0.001). There was no significant association between time-out and the time of the day that the surgery was performed (p = 0.83), nor the number of surgeries performed in the day. Overall, time-out compliance was suboptimal in this study. Time-out was conducted at a similar rate throughout the day, regardless of the surgical load and the length of the pre-incision period.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125467009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and Radiographic Evaluation of Compomer and Composite used for Restoring Primary Teeth 复合材料与复合材料修复乳牙的临床与影像学评价

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.6

O. Meligy, Amani A. Al Tuwirqi

{"title":"Clinical and Radiographic Evaluation of Compomer and Composite used for Restoring Primary Teeth","authors":"O. Meligy, Amani A. Al Tuwirqi","doi":"10.4197/med.26-1.6","DOIUrl":"https://doi.org/10.4197/med.26-1.6","url":null,"abstract":"This study assessed different restorative materials in primary teeth over a one-year period. Sixty carious primary molars were selected from 30 patients; ages 5-10 years. Class I and II cavities were divided into four groups: Group I: 15 Class I cavities were restored with a compomer, Group II: 15 Class I cavities were restored with a resin composite, Group III: 15 Class II cavities were restored with a compomer and Group IV: 15 Class II cavities were restored with a resin composite. Each child had two teeth restored, one with compomer and the other with composite resin as control. Direct clinical and radiographic evaluations were performed by one examiner after 24 hours, 6- and 12-months. Indirect clinical evaluations were performed using a Scanning Electron Microscope after 24 hours and 12-months periodically. Clinical and radiographic evaluations revealed no significant differences between the compomer and resin composite at 6- and 12-months. Indirect clinical evaluation showed good marginal interfaces between the restorations and the tooth structure throughout the evaluation periods. Both materials presented significant clinical and radiographic performances in Class I and II restorations of primary molars after one year.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131985415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mid-Urethral Sling for Stress Incontinence: Does Urodynamic Pressure Reading Affect Post-Operative Outcome? 中尿道吊带治疗压力性尿失禁:尿动压读数是否影响术后预后?

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.3

A. Ghazi, A. Alabbad, Malak Abuzgaya, M. Banakhar, D. Elterman, S. Radomski, M. Hassouna

{"title":"Mid-Urethral Sling for Stress Incontinence: Does Urodynamic Pressure Reading Affect Post-Operative Outcome?","authors":"A. Ghazi, A. Alabbad, Malak Abuzgaya, M. Banakhar, D. Elterman, S. Radomski, M. Hassouna","doi":"10.4197/med.26-1.3","DOIUrl":"https://doi.org/10.4197/med.26-1.3","url":null,"abstract":"The aim of our study was to determine the effect of preoperative urodynamic reading of valsalva leak point pressure on the result of mid-urethral sling surgery. From January 2010 to December 2014, a total of 207 patients underwent mid-urethral sling surgery at the Toronto Western Hospital. An incontinence questionnaire was sent to 94 patients who accepted to be involved in the study to examine satisfaction post-surgery. Forty-five patients replied and were included in the analysis. The patients were divided into three groups according to valsalva leak point pressure (< 60, 60-80 and > 80 cm H2O) determined on urodynamic testing. Of the forty-five patients who responded to the questionnaire, seven were excluded for only having had stress testing done and two were excluded due to intermittent catheterization. Thirteen patients had evidence of detrusor overactivity on urodynamic testing. Simple linear regression analysis was done for the three groups of the valsalva leak point pressure values and correlation to satisfaction was found -0.263, -0.236, and -0.148, respectively. In this current study, we could not find a relation between valsalva leak point pressure values and the self-reported satisfaction post-surgical correction.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127239548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Outcomes of Endotracheal Intubation versus Non-Endotracheal Intubation during Cardiopulmonary Arrest in the Emergency Department 急诊科心肺骤停期间气管插管与非气管插管的结果

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.2

Abdullah A. Bakhsh, Daniah Allali, Ahmad H. Bakhribah, A. Faydhi

{"title":"The Outcomes of Endotracheal Intubation versus Non-Endotracheal Intubation during Cardiopulmonary Arrest in the Emergency Department","authors":"Abdullah A. Bakhsh, Daniah Allali, Ahmad H. Bakhribah, A. Faydhi","doi":"10.4197/med.26-1.2","DOIUrl":"https://doi.org/10.4197/med.26-1.2","url":null,"abstract":"Airway management techniques during cardiopulmonary arrest in the emergency department may impact short and long-term outcomes of these patients. Prior studies addressing airway management of patients in cardiopulmonary arrest in the emergency department are limited. We aimed to evaluate the one-month neurological outcomes post cardiac arrest as a primary endpoint. Our secondary endpoint was to look at return of spontaneous circulation rates and survival to discharge. We retrospectively reviewed cardiac arrest flow sheets of patients sustaining in-emergency department cardiopulmonary arrest between January 2017 and September 2017. We looked at the different types of airway management techniques and their effect on patient outcomes. Patients who received non-endotracheal intubation during cardiopulmonary arrest had higher rates of good neurological outcome (GCS > 9) at one month when compared with patients who received endotracheal intubation: 8 (32%) vs. 2 (5.3%), respectively. Our results revealed a significant association of non-endotracheal intubation (bag-valve mask or laryngeal mask airway) with return of spontaneous circulation rates (p 0.044), survival to discharge (p < 0.001), and good neurological outcome (GCS > 9) (p 0.008). Although non-endotracheal intubation during cardiopulmonary arrest is not common, we encourage the increased use of bag-valve mask and laryngeal mask airways during cardiopulmonary arrest as they are associated with better outcomes.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125328519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Was This the First Case of Isospora belli in Saudi Arabia? 这是沙特阿拉伯的第一例贝利异孢子虫吗?

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.1

M. Wakid

引用次数: 0

Extracorporeal Shockwave Therapy for Acromion Pseudarthrosis 体外冲击波治疗肩峰假关节

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.8

Salman A. Almustafa

{"title":"Extracorporeal Shockwave Therapy for Acromion Pseudarthrosis","authors":"Salman A. Almustafa","doi":"10.4197/med.26-1.8","DOIUrl":"https://doi.org/10.4197/med.26-1.8","url":null,"abstract":"Fracture of acromion is uncommon because of its unique anatomical structure and location. Usually it heals by itself using conservative therapy intervention, and a subject’s shoulder can get back to its functional performance without surgical approach. However, rare cases may not recover due to pseudarthrosis taking place, surgical avoidance plus using noninvasive tools to manage acromion pseudarthrosis with the application of extracorporeal shockwave therapy at medium to high intensity is the author's motivation to report this condition. Likewise, to our knowledge, there is no published literature using extracorporeal shockwave therapy specific to acromion. A case of 36 old male, active, and alert had been referred to the physical therapy outpatient clinic for high density extracorporeal shockwave therapy to manage the acromion pseudarthrosis after going on range of motion and strengthening rehabilitation program for seven months. After having six sessions of extracorporeal shockwave therapy, the acromion nonunion fracture unified, with complete patient recovery. The pain was stopped. The range of motion became full, with the restoration of the shoulder's functional abilities.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128050141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Complications of Hemoglobinopathies in Western Saudi Arabia and the Need for Specialized Care Centers 沙特阿拉伯西部血红蛋白病的临床并发症和对专门护理中心的需求

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.5

M. Badawi, S. Adam, A. Ghoneim, A. Jamjoom, Ahmed N. Sahly, Thunayyan M. Almasoudi, Galila F. Zaher, S. Hindawi

{"title":"Clinical Complications of Hemoglobinopathies in Western Saudi Arabia and the Need for Specialized Care Centers","authors":"M. Badawi, S. Adam, A. Ghoneim, A. Jamjoom, Ahmed N. Sahly, Thunayyan M. Almasoudi, Galila F. Zaher, S. Hindawi","doi":"10.4197/med.26-1.5","DOIUrl":"https://doi.org/10.4197/med.26-1.5","url":null,"abstract":"In the absence of specialized care centers for hemoglobinopathies in Saudi Arabia, there are insufficient data on prevalence of clinical complications in this population. This is a retrospective record review about the clinical complications associated with hemoglobinopathies at King Abdulaziz University Hospital, for patients followed between January 1st 2010 through June 30th 2016. A total of 349 patients were included, with a mean age of 25.45 years, including 266 with sickle cell disease and 80 with thalassemia. Of those receiving regular transfusions, 17.5% developed alloantibodies, 16.6% tested positive for hepatitis C virus antibodies and the mean ferritin level was 2487 ng/ml. Almost half of the patients were screened for renal disease, and more than 50% were found to have proteinuria. Of 203 patients with recent echocardiograms, 15.8% had pulmonary hypertension. Thirty-one (8.9%) patients died at a mean age of 28.5 years. In conclusion, the prevalence of disease related complications is high in hemoglobinopathies. Our results reiterate the need for specialized care hemoglobinopathy centers, which can further improve patient outcomes.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116597145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Multifocal Tuberculosis with Prolonged Paradoxical Reaction 多灶性结核伴长时间矛盾反应

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2019-06-30 DOI: 10.4197/med.26-1.7

E. Al-Ebrahim, T. Madani

{"title":"Multifocal Tuberculosis with Prolonged Paradoxical Reaction","authors":"E. Al-Ebrahim, T. Madani","doi":"10.4197/med.26-1.7","DOIUrl":"https://doi.org/10.4197/med.26-1.7","url":null,"abstract":"This is a case report describing successful treatment of a challenging case of an 18-year old previously healthy high school male student with multifocal tuberculosis involving the spleen and mediastinal and abdominal lymph nodes confirmed by histopathology of splenectomy tissue. The patient initially responded well to antituberculosis therapy with complete resolution of fever and improvement in his general health and weight. However, two months after initiation of anti-tuberculosis therapy, the patient developed paradoxical reaction manifest as recurrence of fever that persisted for five months and was associated with enlargement of lymph nodes. The fever failed to abate with continuation of the same antituberculosis therapy. Despite reassurance that the fever was due to a prolonged paradoxical reaction, a decision was made by the family to seek advice in another hospital where lymphoma was excluded again by histopathological examination of an excisional lymph node biopsy that revealed caseating granulomatous lymphadenitis and negative tuberculosis stain, culture, and polymerase chain reaction. The patient was continued on anti-tuberculosis therapy and treated with corticosteroids that resulted in complete resolution of fever and subsequent full recovery from his tuberculosis.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128010289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Paraganglioma of the Urinary Bladder 膀胱副神经节瘤

Journal of King Abdulaziz University - Medical Sciences Pub Date : 2018-12-31 DOI: 10.4197/MED.25-2.7

Yara A. Fayoumi, Sarah A. Almagharbi, T. Abdel-Meguid, A. Abdelsalam, N. Alghanmi, H. Al-Maghrabi, Raed A. Azhar

{"title":"Paraganglioma of the Urinary Bladder","authors":"Yara A. Fayoumi, Sarah A. Almagharbi, T. Abdel-Meguid, A. Abdelsalam, N. Alghanmi, H. Al-Maghrabi, Raed A. Azhar","doi":"10.4197/MED.25-2.7","DOIUrl":"https://doi.org/10.4197/MED.25-2.7","url":null,"abstract":"Urinary bladder paragangliomas are rare with a reported incidence of <1% of bladder tumors. We presented a case of a urinary bladder paraganglioma in a 26-year-old male who presented with a painless gross hematuria and hypertensive crisis occurring during his trans-urethral resection. Our diagnosis was based upon patient’s history, abdominal-pelvic computed tomography scan, which revealed a left-sided bladder wall mass 2.26 X 4.4 X 3.28 cm that was obstructing the left distal ureter and causing significant left severe hydroureter and hydronephrosis. Preoperative preparation was done with beta blocker and alpha blocker two weeks prior to surgery. The patient underwent an open surgical partial cystectomy, left nephroureterectomy and, complete external and internal iliac lymphadenectomy. Gross pathological examination of the mass revealed a 3x4.5x4 cm growth originating from the wall of the urinary bladder. Microscopic examination revealed nests invaded into muscularis propria of the urinary bladder, with no evidence of distant metastasis. Immunohistochemical studies showed positive tumor cells staining for chromogranin and synaptophysin while S100 highlighted the surrounding sustentacular cells. During the first 3-month post-operative follow-up period, the patient’s blood pressure was stabilized and the symptoms gradually subsided. Urinary bladder paragangliomas should be considered among the differential diagnosis of bladder tumors.","PeriodicalId":318526,"journal":{"name":"Journal of King Abdulaziz University - Medical Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133462220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0