Kristinn Tomasson, Gunnar Gudmundsson, Haraldur Briem, Vilhjalmur Rafnsson
{"title":"Malignant mesothelioma incidence by nation-wide cancer registry: a population-based study.","authors":"Kristinn Tomasson, Gunnar Gudmundsson, Haraldur Briem, Vilhjalmur Rafnsson","doi":"10.1186/s12995-016-0127-4","DOIUrl":"https://doi.org/10.1186/s12995-016-0127-4","url":null,"abstract":"<p><strong>Background: </strong>Malignant mesothelioma caused by asbestos exposure has a long latency period. A ban on asbestos use may not be apparent in decreased incidence in the population until after several decades. The aim was to evaluate changes in the incidence of malignant mesothelioma, and the possible impact of the asbestos ban implemented in Iceland in 1983.</p><p><strong>Methods: </strong>This is a population study on aggregate level; the source of data was the Icelandic Cancer Registry, the National Cause-of-Death Registry, and the National Register. Volume of asbestos import was obtained from Customs Tariff. The import figures reflect fairly accurately the amount used, as there are no mines in the country.</p><p><strong>Results: </strong>Asbestos import peaked in 1980 at 15.0 kg/capita/year, diminishing to 0.3 kg/capita/year ten years after the ban in 1983, and to zero in the most recent years. Seventy-nine per cent of the cases of malignant mesothelioma were men, and 72 % were of pleural origin. Mesothelioma incidence increased steadily from 1965 to 2014, when it reached 21.4 per million among men, and 5.6 among women. Mortality in 2014 was 22.2 per million among men, and 4.8 among women.</p><p><strong>Conclusion: </strong>Malignant mesothelioma incidence and mortality increased in the population during the period, despite the ban on asbestos use from 1983. This is in agreement with the long latency time for malignant mesothelioma. In line with the previously high per capita volume of asbestos import, many buildings, equipment, and structures contain asbestos, so there is an on-going risk of asbestos exposure during maintenance, renovations and replacements. It is thus difficult to predict when the incidence of malignant mesothelioma will decrease in the future. During the last ten-year period, the incidence in Iceland was higher than the recently reported incidence in neighbouring countries.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"37"},"PeriodicalIF":3.0,"publicationDate":"2016-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0127-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34706310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enzo Emanuelli, Enrico Alexandre, Diego Cazzador, Vera Comiati, Tiziana Volo, Alessia Zanon, Maria Luisa Scapellato, Mariella Carrieri, Alessandro Martini, Giuseppe Mastrangelo
{"title":"A case-case study on sinonasal cancer prevention: effect from dust reduction in woodworking and risk of mastic/solvents in shoemaking.","authors":"Enzo Emanuelli, Enrico Alexandre, Diego Cazzador, Vera Comiati, Tiziana Volo, Alessia Zanon, Maria Luisa Scapellato, Mariella Carrieri, Alessandro Martini, Giuseppe Mastrangelo","doi":"10.1186/s12995-016-0124-7","DOIUrl":"https://doi.org/10.1186/s12995-016-0124-7","url":null,"abstract":"<p><strong>Background and aims: </strong>Sinonasal cancers (SNCs) are rare neoplasms, accounting for about 3 % of head and neck cancers, with squamous cell carcinoma (SCC) and adenocarcinoma (ADC) as the most common subtypes. ADCs present strong associations with occupational wood dust exposure. Preventive measures have progressively reduced wood dust concentrations in workplaces but no study has evaluated the effectiveness of such interventions. Few studies indicate associations between ADC and exposure to solvents, which is common in the shoe industry, but this hypothesis still needs confirmation.</p><p><strong>Methods: </strong>In a case-case study, we contrasted 32 ADCs against 21 Non-Adenocarcinoma Epithelial Tumors (NAETs) - all recruited from the same clinical setting (Padua's University Hospital; period 2004-2015) - using questionnaires and clinical records to collect information on potential predictors. Non-occupational factors were age, sex, smoking, allergy and chronic sinusitis. Occupational factors were intensity and frequency of wood dust exposure, protection from wood dust, type of wood (in woodworking); frequency of exposure to leather dust or mastic/solvent (in shoemaking). Odds-ratio (OR), 95 % confidence interval (95 % CI) and two-tail p-values were obtained through stepwise backward logistic regression for each industry, always using as reference patients never employed in either trade and adjusting for non-occupational risk factors.</p><p><strong>Results: </strong>Adjusted OR was 22.5 (95 % CI = 3.50-144; p = 0.001) and 9.37 (95 % CI = 1.29-67.6; p = 0.026), respectively, in patients with low or high degree of protection against wood dust. In the shoe industry, adjusted OR was 1 and 18.8 (95 % CI = 1.29-174; p = 0.030), respectively, in patients with low or high exposure to only mastic/solvent; and 1 and 22.5 (95 % CI = 2.07-244; p = 0.011), respectively, in patients with low or high exposure to only leather dust.</p><p><strong>Discussion and conclusions: </strong>The questionnaire used was able to estimate with simple algorithms past exposures in wood and footwear industries. The case-case design considerably increased the validity of this small study. Results in this study were always consistent with the extant literature; this could support reliability of novel findings. In woodworking, respiratory protective equipment and local exhaust ventilation reduced the risk of occupational SNC; in footwear manufacture, where preventive interventions were seldom adopted, SNC risk was significantly greater for high exposure from mastic/solvent and leather dust.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"35"},"PeriodicalIF":3.0,"publicationDate":"2016-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0124-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34310350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter Grešner, Radosław Świercz, Magdalena Beata Król, Ewa Twardowska, Jolanta Gromadzińska, Wojciech Wąsowicz
{"title":"Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians.","authors":"Peter Grešner, Radosław Świercz, Magdalena Beata Król, Ewa Twardowska, Jolanta Gromadzińska, Wojciech Wąsowicz","doi":"10.1186/s12995-016-0125-6","DOIUrl":"https://doi.org/10.1186/s12995-016-0125-6","url":null,"abstract":"<p><strong>Background: </strong>In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels of selected VOCs in nail salons were also analyzed and tested for associations with seasonal variations of the levels of biomarkers among nail technicians.</p><p><strong>Methods: </strong>The study enrolled 145 female nail technicians and 145 healthy unexposed female controls. The airborne VOCs and levels of biomarkers were assessed by GC-MS chromatography and absorption/fluorescence spectrophotometry, respectively.</p><p><strong>Results: </strong>Plasma levels of thiobarbituric acid reactive species, ceruloplasmin, the activity of glutathione peroxidase (GPx1) and the SOD1/GPx1 activity ratio presented significant differences between the so-called \"hot\" and \"cold\" seasons in the case of nail technicians as well as in unexposed controls (p < <0.0001 for all four biomarkers). The pattern of these variations among nail technicians was found to be significantly different compared to that of the control subjects (p < <0.0001). Although such differences might intuitively be attributed to occupational exposure of nail technicians to VOCs, which was found to be higher during the \"cold\" season compared to the \"hot\" one, our study provided only limited evidence in favor of the hypothesis, that the different pattern of seasonal variations of biomarkers among nail technicians might have resulted from seasonal fluctuations in their occupational exposure to VOCs.</p><p><strong>Conclusion: </strong>Further investigation is thus needed in order to elucidate the effect of low-level occupational exposure to VOCs on seasonal variations of biomarkers of oxidative stress.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"36"},"PeriodicalIF":3.0,"publicationDate":"2016-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0125-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34310351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Ohlendorf, Christoph Mickel, Natalie Filmann, Eileen M Wanke, David A Groneberg
{"title":"Standard values of the upper body posture and postural control: a study protocol.","authors":"Daniela Ohlendorf, Christoph Mickel, Natalie Filmann, Eileen M Wanke, David A Groneberg","doi":"10.1186/s12995-016-0122-9","DOIUrl":"https://doi.org/10.1186/s12995-016-0122-9","url":null,"abstract":"<p><strong>Background: </strong>Decisions on orthopedic interventions on upper body posture and its control have usually resulted from comparisons with the healthy state. Therefore, practitioners as well as scientists in human movement science or orthopedics need access to such kind of data which are patient-centered and well measured. Until now, these data have been missing concerning upper body posture as well as postural control and their control. That is why the aim of the current project is to measure these data with healthy participants across the lifespan.</p><p><strong>Results: </strong>For standard value determination tolerance range and confidence intervals will be calculated. In addition, Pearson- or Spearman-Rank correlations will be used as well as two-sample-t-tests or Mann-Whitney-U-tests for specific group differences. All tests will be two-sided with the level of significance of 5 %.</p><p><strong>Discussion: </strong>This project aims at improving classifications in adaptations of upper body posture and postural control. Measured standard values have not been determined before to this extent. Therefore, interventional effects may become better quantifiable and justiciable.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"34"},"PeriodicalIF":3.0,"publicationDate":"2016-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0122-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34678873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Menen E Mund, Christoph Gyo, Dörthe Brüggmann, David Quarcoo, David A Groneberg
{"title":"Acetylsalicylic acid as a potential pediatric health hazard: legislative aspects concerning accidental intoxications in the European Union.","authors":"Menen E Mund, Christoph Gyo, Dörthe Brüggmann, David Quarcoo, David A Groneberg","doi":"10.1186/s12995-016-0118-5","DOIUrl":"https://doi.org/10.1186/s12995-016-0118-5","url":null,"abstract":"<p><p>Acetylsalicylic acid is a frequently used medication worldwide. It is not used in pediatrics due its association with Reye syndrome. However, in case of pediatric intoxication, children are more fragile to salicylate poisoning because of their reduced ability of buffer the acid stress. Intoxication leads to a decoupling of oxidative phosphorylation and subsequently to a loss in mitochondrial function. Symptoms of poisoning are diverse; eventually they can lead to the death of the patient. Governmental websites of various EU countries were searched for legal information on acetylsalicylic acid availability in pharmacies and non-pharmacy stores. Various EU countries permit prescription-free sales of acetylsalicylic acid in pharmacies and non-pharmacy stores. In Sweden acetylsalicylic acid 500 mg may be sold in a maximum package size of 20 tablets or effervescent tablets in a non-pharmacy. In the UK a maximum of 16 tablets of acetylsalicylic acid 325 mg is allowed to sell in non-pharmacies. In Ireland acetylsalicylic acid is classified as S2 medication. Subsequently, acetylsalicylic acid is allowed to be sold prescription-free in pharmacies and non-pharmacy stores. In the Netherlands acetylsalicylic acid may only be sold in drug stores or pharmacies. A maximum of 24 tablets of 500 mg is allowed to purchase in a drug store. Several countries in the European Union are permitted to offer acetylsalicylic acid prescription-free in pharmacies and non-pharmacy stores without legal guidance on the storage position within the store. Further research is needed to investigate whether acetylsalicylic acid is located directly accessible to young children within the stores in EU countries which permit prescription-free sales of acetylsalicylic acid. </p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"32"},"PeriodicalIF":3.0,"publicationDate":"2016-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0118-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34560916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Schneberger, Gurpreet Aulakh, Shankaramurthy Channabasappa, Baljit Singh
{"title":"Toll-like receptor 9 partially regulates lung inflammation induced following exposure to chicken barn air.","authors":"David Schneberger, Gurpreet Aulakh, Shankaramurthy Channabasappa, Baljit Singh","doi":"10.1186/s12995-016-0121-x","DOIUrl":"https://doi.org/10.1186/s12995-016-0121-x","url":null,"abstract":"<p><strong>Background: </strong>Exposure to animal barn air is an occupational hazard that causes lung dysfunction in barn workers. Respiratory symptoms experienced by workers are typically associated with endotoxin and TLR4 signalling, but within these environments gram negative bacteria constitute only a portion of the total microbial population. In contrast, unmethylated DNA can be found in all bacteria, some viruses, and mold. We hypothesized that in such environments TLR9, which binds unmethylated DNA, contributes to the overall immune responses in the lung.</p><p><strong>Methods: </strong>Using a mouse model, wild-type and TLR9(-/-) mice were exposed to chicken barn air for 1, 5, or 20 days. Blood serum and bronchiolar lavage fluid was tested against a panel of six TLR9-induced cytokines (IL-1β, IL-6, IL-10, IL-12, TNFα, and IFNγ) for changes in expression. Bronchiolar lavage fluid (BAL) was also tested for macrophage as well as monocyte migration.</p><p><strong>Results: </strong>There were significant decreases in serum TNFα after a single day exposure in TLR9(-/-) mice. BAL concentrations of TNFα and IFNγ, as well as TNFα in serum in TLR9(-/-) mice were also reduced after barn exposure for 5 days. After 20 days of exposure IFNγ was significantly reduced in lavage of TLR9(-/-) mice. Myeloperoxidase (MPO) accumulation in the lung was reduced at 20 days of exposure in TLR9(-/-) mice, as was total lavage cell counts. However, Masson's staining revealed no apparent lung histological differences between any of the treatment groups.</p><p><strong>Conclusions: </strong>Taken together our data show TLR9 plays a partial role in lung inflammation induced following exposure to chicken barn air potentially through binding of unmethylated DNA.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"31"},"PeriodicalIF":3.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0121-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34634485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple subcutaneous granulomas and severe rhinitis after intradermal deposition of epoxy: a case report.","authors":"Steffen Roth, Anne Kristin Møller Fell","doi":"10.1186/s12995-016-0120-y","DOIUrl":"https://doi.org/10.1186/s12995-016-0120-y","url":null,"abstract":"<p><strong>Background: </strong>We present an unusual case of subcutaneous granulomas that also highlights the importance of assessing possible associations between exposure and symptoms early in the diagnostic approach to prevent further adverse health effects. Granulomas of the skin are seen in association with several diseases and after foreign body penetration of soft tissue, but have not been described after contact with epoxy. Epoxy resins are commonly used in paints and other protective coatings, including flooring materials.</p><p><strong>Case presentation: </strong>We report a case of granulomatous inflammation in a 58-year-old man after accidental intradermal deposition of unhardened epoxy. Multiple subcutaneous nodules were present on his right forearm, from hand to elbow, for a period of 6 months after the incident. Biopsies and histological analysis showed a granulomatous inflammation without necrosis. Microscopic analysis of the biopsies did not show mycobacterium tuberculosis, other bacteria, or fungal elements. Standard patch testing was negative. The nodules disappeared gradually, but intense pruritus remained. The patient returned to exposure and developed severe work related rhinitis.</p><p><strong>Conclusions: </strong>This case report describes an unusual case of multiple subcutaneous granulomas after a small injury with an epoxy-contaminated tool. Initially no association between the granulomas and exposure was established and the patient returned to work and epoxy exposure. He subsequently developed severe work related rhinitis. The case highlights the challenges of establishing an association between exposure and dermal reactions and that exposure should be reduced or avoided when sensitisation to allergens may have occurred.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"30"},"PeriodicalIF":3.0,"publicationDate":"2016-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0120-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34497769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raffaela Olivieri, Sara Scarnera, Annalisa Ciabattini, Giulia De Vuono, Pietro Manzi, Gianni Pozzi, Giuseppe Battista, Donata Medaglini
{"title":"Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers.","authors":"Raffaela Olivieri, Sara Scarnera, Annalisa Ciabattini, Giulia De Vuono, Pietro Manzi, Gianni Pozzi, Giuseppe Battista, Donata Medaglini","doi":"10.1186/s12995-016-0117-6","DOIUrl":"https://doi.org/10.1186/s12995-016-0117-6","url":null,"abstract":"<p><strong>Background: </strong>Healthcare workers (HCWs) represent a tuberculosis (TB) risk group for a wide range of tasks in healthcare, even in countries with low TB incidence, like Italy. Latent Tuberculosis Infection (LTBI) screening programs are an important tool for TB prevention in these setting.</p><p><strong>Methods: </strong>A retrospective study under a LTBI screening program among HCWs at the Siena University Hospital (Italy), was conducted between September 2011 and July 2015. Tuberculin Skin Test (TST) was used as a first level examination; all TST-positive cases were tested with QuantiFERON-TB Gold In-Tube (QFT-GIT) test, together with a group of TST-negative subjects.</p><p><strong>Results: </strong>Among the 2136 HCWs screened, 144 (6.7 %) were TST-positive and therefore tested with QFT-GIT, confirming a positive result in 36 cases (25 %). Agreement between two tests was poor (k = 0.092; 95 %, Confidence Interval [CI]- 0.048-0.136, p = 0.002). Among TST-positive cases, discordant results occurred more frequently in BCG vaccinated than unvaccinated HCWs (86.3 %, p < 0.001). The probability of a QFT-GIT-positive result increased according to the TST diameter (p = 0.001). No putative risk factor was associated with LTBI occurrence.</p><p><strong>Conclusions: </strong>The use of QFT-GIT test as a second step in TST-positive cases offers an appropriate tool for LTBI detection, especially among BCG-vaccinated HCWs.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"29"},"PeriodicalIF":3.0,"publicationDate":"2016-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0117-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34561510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stéphane Du Mortier, Silas Mukangu, Charles Sagna, Laurent Nyffenegger, Sigiriya Aebischer Perone
{"title":"A decade of an HIV workplace programme in armed conflict zones; a social responsibility response of the International Committee of the Red Cross.","authors":"Stéphane Du Mortier, Silas Mukangu, Charles Sagna, Laurent Nyffenegger, Sigiriya Aebischer Perone","doi":"10.1186/s12995-016-0119-4","DOIUrl":"https://doi.org/10.1186/s12995-016-0119-4","url":null,"abstract":"<p><p>The International Committee of the Red Cross (ICRC) works in fragile States and in armed conflict zones. Some of them are affected by the HIV pandemic. Within the framework of its social responsibility programme concerning HIV affecting its staff members, the organization has implemented an HIV workplace programme since 2004. We carried out a retrospective analysis over 10 years. Data collected were initially essentially qualitative and process-oriented, but were complemented over the years by data on annual voluntary counselling and testing (VCT) uptake and on direct annual costs covering awareness, testing and antiretroviral therapy. The number of people covered by the programme grew from none in 2003 to 4,438 in 2015, with an increase in annual VCT uptake over the years increasing from 376 persons (14 %) in 2007 to 2,663 in 2015 (60 %). Over the years, the services were expanded from awareness raising to bringing VCT to the workplace, as well as offering testing and health coverage of other conditions and innovative approaches to facing challenges linked to situations of violence. Within its social responsibility framework, the ICRC has shown the importance and feasibility of a workplace HIV programme in conflict zones. A sustainable workplace programme in these conflict settings requires constant adaptation, with regular follow-up given the relatively high turnover of staff, and ensuring sustainable stocks of condoms and antiretroviral drugs. </p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"28"},"PeriodicalIF":3.0,"publicationDate":"2016-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0119-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34535569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Terence Khai Wei Tay, Han Zhe Chan, Tunku Sara Tunku Ahmad, Kok Kheng Teh, Tze Hau Low, Nuraliza Ab Wahab
{"title":"Stonefish envenomation of hand with impending compartment syndrome.","authors":"Terence Khai Wei Tay, Han Zhe Chan, Tunku Sara Tunku Ahmad, Kok Kheng Teh, Tze Hau Low, Nuraliza Ab Wahab","doi":"10.1186/s12995-016-0112-y","DOIUrl":"https://doi.org/10.1186/s12995-016-0112-y","url":null,"abstract":"<p><strong>Background: </strong>Marine stings and envenomation are fairly common in Malaysia. Possible contact to various marine life occurs during diving, fishing and food handling. Even though majority of fish stings are benign, there are several venomous species such as puffer fish, scorpion fish, lionfish, stingray and stonefish that require urgent medical treatment. Stonefish is one of the most venomous fish in the world with potential fatal local and systemic toxicity effects to human.</p><p><strong>Case presentation: </strong>We reported a case of stonefish sting complicated with impending compartment syndrome.</p><p><strong>Conclusions: </strong>Medical staff should be alert about the possibility of this potential emergency in standard management of stonefish stings.</p>","PeriodicalId":318500,"journal":{"name":"Journal of Occupational Medicine and Toxicology (London, England)","volume":" ","pages":"23"},"PeriodicalIF":3.0,"publicationDate":"2016-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12995-016-0112-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34378852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}