Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya最新文献_第7页

Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review 脑源性神经营养因子在抑郁症小鼠脑中的表达:系统文献综述

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.6354

Nur Azizah AS, Lysa Veterini, Hafid Algristian, H. M. Salim

{"title":"Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review","authors":"Nur Azizah AS, Lysa Veterini, Hafid Algristian, H. M. Salim","doi":"10.30651/JQM.V5I2.6354","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.6354","url":null,"abstract":"Introduction: Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The different results when these preparations create resistance in cases of chronic depression and actually increase the risk of uncomfortable and even fatal side effects with long-term use.Methods: This Systematic Literature Review uses the PubMed and Google Scholar databases for the period 2015-2020. A total of 322 articles at the beginning of identification and those that met the inclusion criteria in this study were six articles.Results: The results of data extraction showed that the depression condition caused by various stressors resulted in BDNF levels in the hippocampus decreased significantly by p≤0.005.Conclusion: Based on the literature study, it was concluded that in depressive conditions, BDNF levels in the brain decreased.","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78613967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Parental first concern according to age and type in children with ASD 家长首先关注的是自闭症儿童的年龄和类型

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.5738

Dian Dwi Sari, I. Irwanto, A. Suryawan, Mira Irmawati, B. Utomo

{"title":"Parental first concern according to age and type in children with ASD","authors":"Dian Dwi Sari, I. Irwanto, A. Suryawan, Mira Irmawati, B. Utomo","doi":"10.30651/JQM.V5I2.5738","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5738","url":null,"abstract":"AbstractBackground: Developmental problems concerned by parents are a further diagnostic step for children with ASD. Research is needed to find a picture of the child's behavior complained of by parents. Investigations about first concerns among parents of children with ASD and comparisons of the same with children diagnosed with other developmental disorders are rare.Objective: to examine the type and age of parents ‘concern in children with ASD and other developmental disorders.Method:A cross-sectional study was conducted in Child Developmental Centre in Surabaya Indonesia from August 1 to December 30, 2019. T-test and chi-square tests were used to analyze differences in subject variables and types of concern.Result: Most parents of both children diagnosed with ASD and non-ASD indicated first concern were in communication, social skill, and behavior problem. The average age of parents’ first concern of ASD children is 30,14 months. Significant differences were found between ASD and non-ASD groups in communications, behavior, and sensory problem concerns. Conclusion: There is no specific difference between parental concerns of children with ASD and non-ASD children. The average age of first concern was significantly younger for children with an ASD diagnosis than other developmental disorders.Keywords :parent concern, autism, communication.Correspondence :dian_dwisary@yahoo,com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86925987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of positive end-expiratory pressure value on change in end-tidal carbon dioxide as a predictor of fluid responsiveness in Patients Undergoing Passive Leg Raising Maneuver 呼气末正压值对潮末二氧化碳变化的影响，作为被动抬腿操作患者液体反应性的预测因子

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.5458

Lutfi Nur Farid, Hardiono Hardiono, Pesta Parulian Maurid Edwar

{"title":"Effect of positive end-expiratory pressure value on change in end-tidal carbon dioxide as a predictor of fluid responsiveness in Patients Undergoing Passive Leg Raising Maneuver","authors":"Lutfi Nur Farid, Hardiono Hardiono, Pesta Parulian Maurid Edwar","doi":"10.30651/JQM.V5I2.5458","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5458","url":null,"abstract":"Abstract Identification of patients’ fluid status in the emergency room should be made before giving fluid therapy. This study aimed to determine the effect of positive end-expiratory pressure on change in end-tidal carbon dioxide during passive leg raising maneuver to predict fluid responsiveness. Thirty subjects aged 18-65 years in the resuscitation room, all on the ventilator, were divided into three groups according to their positive end-expiratory pressure value: low (0-5 cmH2O), moderate (6-10 cmH2O), and high (>10 cmH2O). Every subject underwent passive leg raising to simulate fluid administration. Values of blood pressure, heart rate, cardiac output, and end-tidal carbon dioxide were recorded before and after the maneuver. Analysis of the three groups found a significant correlation between change in end-tidal carbon dioxide with a cut-off value of 5% and 1 mmHg with fluid responsiveness of subjects in the low (p = 0.028) and moderate (p = 0.013) but not in the high positive end-expiratory pressure group (p = 0.333). In conclusion, change in end-tidal carbon dioxide in mechanically ventilated patients undergoing passive leg raising maneuvers can be used as a predictor of fluid responsiveness, but this method cannot be used on patients with high positive end-expiratory pressure (> 10 cmH2O) Keywords : change in end tidal carbon dioxide, fluid responsiveness, positive end-expiratory pressure, passive leg raising, cardiac output surrogateCorrespondence : lutfithe13th@gmail.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73375686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anosmia and covid-19 in Yogyakarta, Indonesia: a case series 印度尼西亚日惹的嗅觉缺失与covid-19:一个病例系列

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.7502

Rizka Fakhriani, Asti Widuri

引用次数: 0

Relationship between modified Nutrition Risk in the Critically Ill (mNUTRIC) Score and nutrition intake with quadriceps femoris muscle thickness in critically ill patients 危重患者营养风险修正(mNUTRIC)评分与营养摄入及股四头肌厚度的关系

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.6257

Mahendra Dwi Aditya Lopulalan, P. Airlangga, Arie Utariani

{"title":"Relationship between modified Nutrition Risk in the Critically Ill (mNUTRIC) Score and nutrition intake with quadriceps femoris muscle thickness in critically ill patients","authors":"Mahendra Dwi Aditya Lopulalan, P. Airlangga, Arie Utariani","doi":"10.30651/JQM.V5I2.6257","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.6257","url":null,"abstract":"Abstract Muscle wasting in critical illness is seen from inadequate nutrition intake and stress catabolism. Modified Nutrition Risk in the Critically Ill (NUTRIC) Score is a screening tool that measures starvation, inflammation, disease severity, and organ dysfunction. Relationship between muscle strength and muscle thickness causes the evaluation of muscle thickness is quite relevant. This study aimed to analyze the relationship between modified NUTRIC score and nutrition with muscle wasting in critically ill patients. The study was conducted on 30 patients in the ICU Dr Soetomo Hospital Surabaya. Nutritional intake and thickness of the quadriceps femoris muscle were monitored for one week. There was a relationship between mNUTRIC score with quadriceps femoris muscle thickness on days 3rd, 5th, and 7th. In the comparison between the low risk group and the high-risk group, it was found that there was a significant difference in the change in the percentage of muscle thickness difference on the 3rd, 5th and 7th day observation. There is a relationship between protein debt with quadriceps femoris muscle thickness (p = 0.008) with a positive correlation with moderate correlation strength (r = 0.477) on day 7. In conclusion, the modified NUTRIC Score had a moderate relationship with quadriceps femoris muscle thickness in critical patients from day 3rd until day 7th. The calorie intake not had a relationship with quadriceps femoris muscle thickness. Protein intake had a moderate relationship with quadriceps femoris muscle thickness only on day 7th measurement in critical patients. Keywords : Modified NUTRIC Score, Nutrition, Quadriceps Femoris muscleCorrespondence : mdr.lopulalan@gmail.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90515726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nephroprotective effect of virgin coconut oil in Plasmodium berghei ANKA infected Balb/c mice 初榨椰子油对伯氏疟原虫ANKA感染Balb/c小鼠的肾保护作用

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.5791

Syafarinah Nur Hidayah Akil, H. Arwati, Puspa Wardhani, P. A. Wiratama

{"title":"Nephroprotective effect of virgin coconut oil in Plasmodium berghei ANKA infected Balb/c mice","authors":"Syafarinah Nur Hidayah Akil, H. Arwati, Puspa Wardhani, P. A. Wiratama","doi":"10.30651/JQM.V5I2.5791","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5791","url":null,"abstract":"AbstractMalaria is a parasitic infectious disease caused by Plasmodium, which remains a world health problem with an estimated 219 million cases worldwide. In severe malaria infection, several organs of the body can be affected, including the kidneys. One of the pathophysiology associated with the worsening of this disease is oxidative stress. The use of antioxidants is expected to prevent this, and one product that has a high antioxidant content is virgin coconut oil (VCO). This study aimed to analyze the effect of VCO on the kidney in Plasmodium berghei ANKA-infected mice. This study was an in vivo laboratory experimental study with a randomized post-test only control group design using 35 BALB/c mice infected with P. berghei ANKA, weighing 20-30 grams. VCO with the Javara® brand is used with doses of 1, 5, and 10 ml/kg body weight (kgBW)/ day. The parameter assessed were levels of BUN, creatinine, and renal histopathological changes. The administration of VCO on the treated group shows minimal tubular necrosis and glomerulonephritis compared to the negative control group. The BUN and creatinine levels in the treated group were also lower than the negative control group. The results showed that VCO has a nephroprotective effect against P. berghei ANKA infection in mice.Keywords: malaria, kidney, virgin coconut oil","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74391679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding Pacing-Induced Cardiomyopathy: a mini review 了解起搏性心肌病:一个小回顾

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.6036

S. Purwowiyoto, Reynaldo Halomoan Siregar, S. P. Surya

引用次数: 0

Prevalence and risk factors of Ascaris lumbricoides infection in children of Manusak Village, Kupang District, East Nusa Tenggara Province, Indonesia 印度尼西亚东努沙登加拉省库邦区马利萨克村儿童类蚓蛔虫感染的流行及危险因素

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.5191

Meliance Bria, H. Arwati, I. Tantular

{"title":"Prevalence and risk factors of Ascaris lumbricoides infection in children of Manusak Village, Kupang District, East Nusa Tenggara Province, Indonesia","authors":"Meliance Bria, H. Arwati, I. Tantular","doi":"10.30651/JQM.V5I2.5191","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5191","url":null,"abstract":"ABSTRACT Worm infection is one of the health problems in all tropical countries, including Indonesia. The most frequent helminthiasis is the infection caused by the Soil-Transmitted Helminth. Primary school-age children are an age group that is susceptible to helminthiasis. Worm infections can cause a serious impact if left untreated with no clean and healthy lifestyle. This study was conducted to determine the prevalence and risk factors of STH in children of Manusak Village, East Kupang Subdistrict, Kupang District, East Nusa Tenggara Province, followed by the characterization of subjects. The analytic observational design with the cross-sectional study was applied to this research. Research subjects were 130 children aged 6-12 years old. The infection was diagnosed microscopically by the Katokatz method. Ascaris lumbricoides were the only species found infecting a total of 50 children (38.4%.). The distribution of ascariasis was higher in girls (30 or 23.08%) than in boys (20 or 15.38%), in children whose parents have no formal education (41 or 31.54%), and who their professions are a farmer. Poor hygiene and sanitation such as no washing hands with soap (27 or 20.77%) as well as the habit of not wearing footwear (47 or 36.2%) and bowel habit on the open areas (35 or 26.92%) are the risks factors causing the high incidence of A. lumbricoides in the studied area. Enlightenment to the parents regarding good personal and environmental hygiene and sanitation along with chemotherapy from the government and related agencies is needed to achieve a durable reduction of the burden of ascariasis and other STH infection. Keywords : Soil Transmitted Helminth, Ascaris lumbricoides, children, Kupang DistrictCorrespondence : heny-a@fk.unair.ac.id","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90728906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Palpebral Non-Hodgkin Lymphoma with Non-specific Reactive Hepatitis 眼睑非霍奇金淋巴瘤合并非特异性反应性肝炎

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.7550

P. Z. Romadhon, B. A. Mahdi, U. Y. Bintoro

引用次数: 0

Comparison of central vein pressure between distal, medial, and proximal lumens with water manometer method 水压计法测定远、中、近端管腔中心静脉压力的比较

Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya Pub Date : 2021-07-24 DOI: 10.30651/JQM.V5I2.5356

Cornellius Hendra Purnama Aria Sumantrie, B. Semedi, B. Purwanto

{"title":"Comparison of central vein pressure between distal, medial, and proximal lumens with water manometer method","authors":"Cornellius Hendra Purnama Aria Sumantrie, B. Semedi, B. Purwanto","doi":"10.30651/JQM.V5I2.5356","DOIUrl":"https://doi.org/10.30651/JQM.V5I2.5356","url":null,"abstract":"ABSTRACT Catheter Vein Pressure in ward-cared patients is rarely measured and considered invalid. The two catheter vein pressure postulates contradict, making confusion among health workers. Dr Russo said the distal-medial-proximal Catheter Vein Pressure has no difference but were denied by Susan S. Scott. Proof of postulate is needed as a solution to inward care. Therefore, this study aimed to compare the central vein pressure between distal, medial, and proximal lumens with the water manometer method. Forty-nine samples retrospective study were taken from the distal - medial - proximal Catheter Vein Pressure of the \"zero\" until fifth days. The differences are analyzed with Statistical Paired t Test with p-Value < 0.05 from SPSS ver. 26 to prove the right postulate. 49 samples were concluded to represent of population. Catheter Vein Pressure from day \"zero\" becomes zero difference, the fifth day 91.8% are no difference while the rest have difference of 0.2 - 1.0 cm H2O and the conclusion are no significant difference with 95% CI. The correlation scale of 0.998 and 0.999 proves that the three lumens tend to produce no differences. In conclusion, the distal - medial - proximal Catheter Vein Pressure values in this study have no significant differences and consistent from \"zero\" until fifth days. This is formulated as P distal = P medial = P proximal (cm H2O). Keywords : Central Vein Pressure, Pressure, distal - medial - proximal, no differences, ward patient. Correspondence : sumantrie_medicalgp@yahoo.com","PeriodicalId":31682,"journal":{"name":"Qanun Medika Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90720203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0