IJFAC Indonesian Journal of Fundamental and Applied Chemistry最新文献

{"title":"Preconcentration of Cr(III) Using Dowex 50WX2-200 Resin and Its Application to River Water","authors":"S. Nuraini, S. Suheryanto, P. Hariani","doi":"10.24845/ijfac.v8.i2.105","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.105","url":null,"abstract":"Cr(III) is one of the most stable chromium species in nature, Cr(III) species are not carcinogenic to humans, but if the levels in the body exceed 0.2 mg / day it is very dangerous for the body especially in the respiratory tract. The presence of chromium in the aquatic environment is so low that it is very difficult to detect it using instruments with various limitations to detect it, therefore preconcentration techniques are carried out to overcome the issue. In this study the water sample was adjusted pH using HNO3 0.1 M or NaOH 0.1 M, after which it was passed in the dowex column 50WX2-200. Furthermore, an elution process was carried out using the 1 M HNO3 eluent, the eluat was measured for absorbance with flame AAS. The results of Cr(III) preconcentration optimization are: resin weight 0.5 g, HNO3 eluent concentration 1 M, solution pH 3 and sample volume 50 – 100 mL. The Cr(III) preconcentration technique using Dowex 50WX2-200 resin has been applied to river water samples with a detectable concentration of 0.0075 mg/L.","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82245801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coumarin Derivative from the Unripe Fruit of Mengkudu (Morinda citrifolia Linn) and Cytotoxic Activity","authors":"Ferlinahayati Ferlinahayati, Sarifatun Nisa, H. Hermansyah, D. Basir","doi":"10.24845/ijfac.v8.i2.70","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.70","url":null,"abstract":"A coumarin derivative namely scopoletin (7-hydroxy-6-methoxychromen-2-one)had been isolated from the methanol extract of unripe noni fruits (Morinda citrifolia Linn.). The extraction was conducted by maceration, continuing with separation and purification using several techniques of chromatography. The yellowish isolated compound showed a melting point at 200 – 202 C. The compound structure was analyzed based on spectral data 1H-NMR, 13C-NMR, and NOE 1D. The inhibition of methanol extract of noni fruits and scopoletin against murine leukemia P388 cells using MTT assay showed IC50 were > 100 μg/mL and 65.69 μg/mL respectively. These showed that scopoletin was more cytotoxic than methanol extract but weaker than artonin E as a positive control IC50 0.48 μg/mL).","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86798670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flavonoid as Anti-Candida Agents","authors":"S. Susilawati, C. Anwar, Irsan Saleh, Salni Salni","doi":"10.24845/ijfac.v8.i2.88","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.88","url":null,"abstract":"Vulvovaginal candidiasis is the second most common cause of vaginitis after bacterial vaginosis with at least 75 – 80% of women have had one episode of VVC in their lifetime. Their prevalent resistance to most commonly used antifungal agents makes their treatment a challenge to physicians. Flavonoids have been shown to possess potent anti-Candida properties which can inhibit the growth and proliferation of Candida species through various mechanisms, including inhibition of fungal cell wall synthesis, disruption of fungal cell membrane integrity, and interference with fungal cell signaling pathways. Their potency makes them potential candidates for the development of antifungal agents for the treatment of candidiasis, alone or in combination with existing antifungal drugs. The review aims to explore the mechanisms by which flavonoids inhibit the growth and proliferation of Candida species, including the inhibition of fungal cell wall synthesis, disruption of fungal cell membrane integrity, and interference with fungal cell signaling pathways.","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79340288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of Zirconium Nitride supported on SiO2 Catalyst for Vegetable Oil Conversion","authors":"W. R. Asri, H. Hasanudin, K. Wijaya","doi":"10.24845/ijfac.v8.i2.98","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.98","url":null,"abstract":"Hydrocracking of crude palm oil (CPO) to produce biofuels was conducted over zirconium nitride supported on SiO2 (SiO2/ZrN) catalyst. SiO2/ZrN was prepared by nitriding the SiO2/Zr at 600 C for 3 hrs under NH3 gas on the cylindrical reactor. SiO2/ZrN exhibited a surface acidity of 0.7132 mmol pyridine g‒1 with a surface area of 96 m2 g‒1, forming predominant mesopores on the catalyst. EDS- mapping analysis showed that the ZrN species exhibited a highly distributed on the SiO2 surface. CPO hydrocracking was conducted at a temperature of 500 C for 1 hr, with a CPO flow rate of 0.02 L min‒1 and H2 flow rate of 0.03 L min‒1. The study revealed that the SiO2/ZrN successfully afforded a CPO conversion up to 94.98 wt.%, a liquid yield of 50.40 wt.%, with a low residue and coke formation. This catalyst promoted high selectivity towards bio-jet up to 72.95 wt.%.","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75035447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Boron Complexation with Pyridoxine: Effect of Interaction Time, Temperature, and Amount of Pyridoxine","authors":"N. Hidayati, Ariqah Fianti, Mita Arnela","doi":"10.24845/ijfac.v8.i2.76","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.76","url":null,"abstract":"Borax is one of the compounds of boron (B), which is widely used as an anti-fungal, wood preservative, and antiseptic in cosmetics. Boron can form complexes with biomolecules such as pyridoxine, so it is interesting to know the interaction between borax and pyridoxine. This study seeks to investigate the complexation of boron, which is obtained from borax, with pyridoxine under various conditions of time, temperature, and the amount of pyridoxine. The resulting complex was characterized by UV-Vis spectrophotometry, Fourier Transform Infrared (FT-IR), and X-Ray diffraction (XRD). The study was initiated by optimizing the complexation of boron and pyridoxine. The maximum wavelengths of pyridoxine were found in the 205 nm and 292 nm regions, while the boron-pyridoxine complex was found in the 237 nm region. The obtained contact time, temperature, and amount of pyridoxine are 40 minutes, 60 °C, and 2 mL respectively. The results of the Fourier transform infrared (FT-IR) analysis of the boron-pyridoxine complex showed that there were OH groups, aromatic C=C groups, aliphatic C-C groups, B-H groups, and B-O groups. The results of the XRD analysis of the boron-pyridoxine complex obtained a diffraction angle of 30.93°","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79147463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Lead (Pb) and Cadmium (Cd) in Oyster Crassostrea gigas and Saccostrea cucullata using Atomic Absorption and Ultraviolet-Visible Spectrophotometer Methods","authors":"Lelifajri Lelifajri, Salsabila Salsabila, Khairi Suhud","doi":"10.24845/ijfac.v8.i2.55","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.55","url":null,"abstract":"Lead (Pb) and Cadmium (Cd) metals are highly toxic when accumulated in the body and cause serious diseases and even death. This study aimed to determine the metal content of Pb and Cd in the oyster species Crassostrea gigas and Saccostrea cucullate in the Lampulo and Krueng Cut areas at three different places. Analysis of the metals was carried out using AAS and UV-Visible spectrophotometers. Samples were prepared using concentrated HNO3 wet destruction and the addition of dithizone. The results showed Pb measured by AAS in Saccostrea cucullata 2.33-8.00 ppb, and by UV-Vis 2.77-8.66 ppb. Pb within Crassostrea gigas by AAS method 1.77-10.30 ppb, and by UV-Vis method 2.11-10.66 ppb. The Cd metal measured by AAS in Saccostrea cucullate is 3.80-10.50 ppb, and by UV-Vis method is 4.29-10.77 ppb, whereas Cd in Crassostrea gigas measured by AAS is 12.11-13.22 ppb and by UV-Vis method is 12.77-13.66 ppb. Linearity of Pb measurements with AAS and UV-Vis was obtained R2 =0.9979 and R2 =0.9938 and for Cd were R2 =0.9986 and R2 =0.9810. Accuracy (%recorvery) of Pb measurements by AAS and UV-Vis are 80-110% and 98-113% whereas Cd showed 100-106% and 91-107% respectively. The relative value of the standard deviation (%RSD ± SD) is 0.001 indicating excellent measurement results. Based on t-test calculations, measurements of Pb and Cd levels showed no difference between the AAS method and the UV-Vis method","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73287887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial Compound from n-Hexane Fraction of Dillenia ochreata Leaves","authors":"H. Yohandini, M. Muharni, Putra Setia Aji Candra","doi":"10.24845/ijfac.v8.i2.63","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.63","url":null,"abstract":"Semprawang (Dillenia ochreata) belongs to the Dilleniaceae family that has been used by the Musi tribe, Banyuasin, South Sumatra, for scurvy medicine. This study aims to isolate secondary metabolites from D. ochreata leaves n-hexane extract and test their antibacterial activity against Escherichia coli and Staphylococcus aureus. The D. ochreata leaves were extracted through the maceration method with n-hexane solvent, and the isolated compounds were purified using column chromatography. The isolated compounds were analyzed using FT-IR, 1H-NMR, and 13C-NMR spectroscopy and compared the spectroscopic data with the literature. The antibacterial activity was determined against the E. coli and S. aureus bacteria with the disc diffusion method and MIC value was determined by the microdilution method. Based on the analysis of the spectroscopic data and compared with literature data, it is suggested that the isolated compounds are 3β-glucopyranosyl-lup-20(29)- en-28-oic, which mixes with aromatic compound. The isolated compounds showed antibacterial activity with a minimum inhibitory concentration (MIC) to E. coli at 120 μg/mL and S. aureus at 60 μg/mL","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78432328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Characterization of Cellulose Acetate from α-Cellulose of Paper Waste","authors":"Ristika O Asriza, Nurhadini Nurhadini, Fardhan Arkan","doi":"10.24845/ijfac.v8.i2.82","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i2.82","url":null,"abstract":"A cellulose derivative substance called cellulose acetate is frequently used in the manufacturing of photographic film, fiber, membranes, and bioplastics. However, the availability of sources for cellulose acetate's raw material does not support this demand. Paper waste has a high cellulose content. Therefore, the aim of this research is to synthesize cellulose acetate from α-cellulose waste paper. In order to separate alpha cellulose from waste paper in this study, the delignification process with NaOH solvent was used as a first step. After obtaining alpha cellulose, acetic anhydride was used to carry out the acetylation reaction. The yield of α-cellulose from paper waste is 51.8%. α-Cellulose is reacted with acetic anhydride through acetylation reactions and hydrolysis of acetyl groups. From this reaction, functional groups -OH, C=O ester, and C-O acetyl appeared from the FTIR spectra analysis which indicated that cellulose acetate had been successfully synthesized. The type of cellulose acetate produced is a type of cellulose monoacetate with an acetyl groups of 23% and a degree of substitution value of 1.17","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"210 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134958707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polypropylene and some Esterified Plants' Fibers Bio-based Composites","authors":"Nawal M. Suleman, Eiman M. Eltyeb, Abuelgasim. Abbaker Abedelrasoul. Mohammed","doi":"10.24845/ijfac.v8.i1.48","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i1.48","url":null,"abstract":"This study aimed to synthesize bio-based composites from polypropylene and some esterified plants' fibers extracted from khimp (leptadenia pyrotechnica), leaves, and fibers of the date palm tree (Phoenix dactylifera L.). 24 composites in form of sheets were synthesized by injection molding technique using a modified manually operated injection molding machine. Properties like density, melting range temperature, melt flow rate, molecular weight, melt viscosity and water absorption capacity were determined for each synthetic composite. The study employed MFR and ordinary laboratory tools. The study proved that the synthesized composites are of good process ability, physical and thermal properties and have more densities than polypropylene itself","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89416921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delignification and Adsorption Research of Bioethanol Process using Pseudostem of Musa Balbisiana (Pisang Klutuk) as the Blending Raw Material to Gasohol","authors":"Rafit Arjeni, Abu Hasan, Aida Syarif","doi":"10.24845/ijfac.v8.i1.1","DOIUrl":"https://doi.org/10.24845/ijfac.v8.i1.1","url":null,"abstract":"Indonesia is a country that has the most energy sources in the Southeast of Asia and the fifth in Asia-Pacific subsequent to China, India, Japan and South Korea. Energy usage in Indonesia in 2016 was still dominated by 47% fuel oil. If the energy usage increases continuously, energy sustenance and resilience in Indonesia will be plagued. Therefore, there is a necessary to utilize the alternative energy sources that would be earth-friendly as well New and Renewable Energy (EBT) like bioethanol. Bioethanol can be produced by organic wastes, pseudostem of Musa Balbisiana (Pisang Klutuk) as the example. This research is focused on the study of delignification and adsorption of the process of bioethanol using pseudostem of Musa Balbisiana as the blending raw material to gasohol. The process started with the pre-treatment and delignification of the pseudostem of Musa Balbisiana with the sorts of NaOH concentration including the following of 10%, 20%, 30% and 100oC, 125oC, 150oC, 175oC, dan 200oC for the heating temperatures. In delignification, it can be stated that the concentration of 10% NaOH on 150oC temperature produced the finest cellulose and lignin content with the amount of 81,3% cellulose and 10,1% lignin. The pseudostem fibers that have passed the process of delignification, was done to the process of hydrolysis and fermentation for producing bioethanol. The result of Bioethanol was carried out to the process of distillation for separating bioethanol and water. Continuing the process, bioethanol was purified in adsorption and distillation process. In adsorption, the 5gr, 10gr, 15gr, 20gr, and 25gr adsorbent alloyed to the purified bioethanol, and it can be claimed that the highest rate of purified bioethanol is 20gr with the 99,11% bioethanol content. The 99,11% bioethanol content was blending with Pertalite with the ratios of 5:95, 10:90, 15:85, 20:80, and 25:75, thereafter it was analyzed the RON content which obtained the highest point that is 97,48 on 25:75 ratio.","PeriodicalId":31600,"journal":{"name":"IJFAC Indonesian Journal of Fundamental and Applied Chemistry","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83497044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}