Proceedings of 2nd Coatings and Interfaces Web Conference最新文献

{"title":"New Advances on Fibroblast Growth Factor-Based Coatings for Hip Replacement Implants","authors":"I. C. Nica, M. Stan, A. Dinischiotu, V. Grumezescu, A. Stoica, A. Holban, A. Grumezescu","doi":"10.3390/ciwc2020-06844","DOIUrl":"https://doi.org/10.3390/ciwc2020-06844","url":null,"abstract":"It is already well known that the tissue–implant interface is one of the most critical factors for the success of implant integration. The use of bioactive and biomimetic surfaces is of great interest in biomedical applications, especially in tissue engineering. Therefore, in our study, we aimed to obtain successful coatings based on hydroxyapatite, antibiotics and growth factors in order to increase the biocompatibility of commercial implant materials by promoting cell attachment and growth without toxic effects, as well as the inhibition of microbial biofilm formation. In this way, homogenous mixtures of hydroxyapatite, kanamycin and fibroblast growth factor (HAP/KAN, HAP/FGF and HAP/KAN/FGF) were coated on titanium-based metal plates for hip replacement implants. The coatings were able to impair the initial adherence of bacterial cells and to reduce biofilm formation throughout the release of antibiotics. The cytocompatibility of these samples was investigated on normal murine osteoblasts (MC3T3-E1 cell line) with fibroblast-like morphologies by evaluating their influence on cellular viability and their potential to generate an inflammatory response. In addition, adhesion and proliferation, as well as actin cytoskeleton organization, were observed after 24 h of cell culture on these coatings. The results confirmed the biocompatibility of all coatings, with the cell number counted for the HAP/KAN/FGF sample being equal to the control. Since it is well known that NO is a marker of inflammation with an essential role in regulating apoptotic cell death and cell viability, our study showed that cell growth on these surfaces did not induce nitric oxide (NO) release, with the NO level being maintained close to control values for all tested samples. Moreover, an excellent cell adherence and spreading on these coatings deposited on hip implants was evidenced by fluorescence microscopy, supporting their usage as substrates in tissue engineering applications.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127060011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resistance to Cavitation Erosion and Sliding Wear of MCrAlY and NiCrMo Metallic Coatings","authors":"M. Szala, M. Walczak, L. Łatka, K. Gancarczyk","doi":"10.3390/ciwc2020-06846","DOIUrl":"https://doi.org/10.3390/ciwc2020-06846","url":null,"abstract":"Bulk cobalt- and nickel-based metallic materials exhibit superior resistance to cavitation erosion and sliding wear. Thus, thermally deposited High-Velocity Oxygen Fuel (HVOF) coatings seem promising for increasing the wear resistance of the bulk metal substrate. However, the effect of chemical composition on the cavitation erosion and sliding wear resistance of M(Co,Ni)CrAlY and NiCrMo coatings has not yet been exhaustively studied. In this study, High-Velocity Oxygen Fuel (HVOF) coatings such as CoNiCrAlY, NiCoCrAlY, and NiCrMoFeCo were deposited on AISI 310 (X15CrNi25-20) steel coupons. The microstructure, hardness, phase composition and surface morphology of the as-sprayed coatings were examined. Cavitation erosion tests were conducted using the vibratory method in accordance with the ASTM G32 standard. Sliding wear was examined with the use of a ball-on-disc tribometer, and friction coefficients were measured. The mechanism of wear was identified with the scanning electron microscope equipped with an energy dispersive spectroscopy (SEM-EDS) method. In comparison to the NiCrMoFeCo coating, the CoNiCrAlY and NiCoCrAlY coatings have a lower sliding and cavitation wear resistance.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"30 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116392772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Studies on HVOF Sprayed Coatings on the Magnesium Alloys","authors":"E. Jonda, L. Łatka, G. Więclaw","doi":"10.3390/ciwc2020-06847","DOIUrl":"https://doi.org/10.3390/ciwc2020-06847","url":null,"abstract":"In the field of the development of modern techniques, which improve and/or regenerate the component’s surface properties, High Velocity Oxygen Fuel (HVOF) spraying of carbides or metals and their alloys is a good alternative method to other conventional surface engineering ones, including magnesium foundry alloys. Coatings manufactured by thermal spraying are used to improve the durability and life time of machine parts, both the new and regenerated ones, by changing the surface layer properties. In this work the results of HVOF sprayed coatings deposited onto AZ31 magnesium alloy substrate are reported. The feeding material was composite powder Cr3C2–NiCr. The coatings were investigated in terms of their microstructure and selected mechanical properties. For structure examinations, microscopy studies (light and scanning ones) were used as well as phase composition analysis. In the case of mechanical properties, the wear resistance was determined also microhardness was measured.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125844366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2D and 3D Electrospun Silk Fibroin Gelatin Coatings to Improve Scaffold Performances in Cardiovascular Applications","authors":"M. Tanzi, C. Marcolin, L. Draghi, S. Faré","doi":"10.3390/ciwc2020-06843","DOIUrl":"https://doi.org/10.3390/ciwc2020-06843","url":null,"abstract":"3D scaffolds and 2D matrices fabricated by electrospinnig show morphology similar to that of native ECM, however their mechanical and biological properties are often inadequate, particularly in applications in contact with blood, e.g. in blood vessel substitutes. Biocoatings can improve the performance of these substrates, in particular cross-linked gelatin is among the most used substances. \u0000In this work, a gelatin coating was applied to electrospun silk fibroin (ESF) mats and tubes intended for the regeneration of cardiovascular tissues. The crosslinking reaction used is based on a Michael-type addition in water that promotes the formation of covalent bonds between gelatin amino groups and β-carbons of N-N’-methylene bis-acrylamide (MBA)[1]. \u0000Interestingly, when the reacting mixture is applied to a substrate containing primary or even secondary amino groups, these groups can participate in the reaction, being incorporated into the gelatin coating, thus increasing the coating stability on the surface. \u0000ESF mats and tubes, obtained as described in [2] were coated with gelatin MBA-crosslinked in situ by loading or dipping the ESF samples with the crosslinking solution, by use of static or dynamic home-made systems. SEM analysis on coated samples showed a homogeneous coating with gelatin penetrating the whole thickness of the SF matrix {»120 µm for mats and » 212 µm for tubes), with an increase of thickness of about 40% in wet conditions. Water uptake tests indicated for coated samples a faster and higher swelling (1600% after 14 days) than not coated ones (500%), due to the presence of gelatin. \u0000Tensile mechanical tests showed higher values of ultimate stress and elastic modulus for silk fibroin samples (sb=2.4, E=1.82 MPa) compared to gelatin-coated ones (sb=1.2, E=0.58 MPa), with not significant differences in the ultimate deformation (»150%). \u0000Indirect cytocompatibility tests, performed by culturing L929 cells in the presence of eluates obtained by immersing coated and uncoated samples up to 7 days in culture medium, demonstrated a cell viability higher than the control. In direct contact tests using L929 cells, a good cytocompatibility was demonstrated by both coated and uncoated ESF samples, with a cell viability increasing with the culture time (up to 7 days) and a flattened and stretched morphology at SEM. \u0000Primary human umbilical vein endothelial cell (HUVEC), obtained by enzymatic digestion (Cittadella Hospital, PD,I) were seeded onto ESF and ESF-coated samples and cultured under standard tissue culture conditions. Cell adhesion on the matrices was analysed by OM after fixing with formalin and staining with toluidine blue. After 7 days from seeding, cell proliferation was evaluated by a protein assay (BCA Protein Assay kit) and the results indicated a significantly higher (p<0.05) cell growth on gelatin-coated ESF samples. \u0000Overall, these results point out that the described gelatin coating allows producing a structure with adequate mecha","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130461682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid Oxidation of Titanium Substrates for Biomedical Applications","authors":"J. Jasinski","doi":"10.3390/ciwc2020-06845","DOIUrl":"https://doi.org/10.3390/ciwc2020-06845","url":null,"abstract":"Titanium oxidation for biomedical applications is still a challenge in obtaining favorable mechanical and physicochemical properties of thin oxide layers, as well as the required high bioactivity. Interesting techniques for TiO2 layer formation are electrochemical, plasma and diffusive methods. Each method aims to create a thin oxide layer characterized by thermal stability and re-passivation in the presence of a simulated body fluid SBF environment. However, an important aspect here is also the phase composition of oxide layers, essential for osseointegration. Accordingly, the research carried out aims to produce such a titanium substrate, where the surface zone is a Tiα(O) solid solution formed with fluidized bed (FB) diffusion process (640 °C, 8 h) and the top layer is TiO2 produced by physical vapour deposition PVD—magnetron sputtering. The effects of such hybrid oxidation on titanium surface properties were investigated with scanning electron microscopy SEM/scanning transmission electron microscopy STEM/ Raman spectroscopy RS and nanoindentation tests. The results showed that hybrid oxidation made it possible to generate a favorable synergetic effect between FB and PVD oxide layers and to reduce the stresses at their interface. In turn, a variable share of TiO2 phases (rutile + anatase mixture) obtained at the titanium surface allowed for the significant enhancement of hydroxyapatite compound growth, which was confirmed by a 14-day Kokubo test.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125828051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NiOOH/FeOOH Supported on Reduced Graphene Oxide Composite Electrodes for Ethanol Electrooxidation","authors":"J. Oliveira, A. C. Sá, L. Paim","doi":"10.3390/ciwc2020-06840","DOIUrl":"https://doi.org/10.3390/ciwc2020-06840","url":null,"abstract":"In this work, nickel (Ni) and Ni-Fe bimetallic microparticles were electrosynthesized at reduction potentials in the range from −0.70 V to −1.20 V (50 mV s−1) by cyclic voltammetry (CV) onto graphite/paraffin electrode surface modified with nanosheets of reduced graphene oxide (RGO). Previously, the RGO was electrodeposited by CV from a suspension of 1 mg mL−1 of graphene oxide in PBS solution with pH 9.18, in the potential range from −1.50 V to 0.50 V (10 mV s−1). After electrodeposition of metals, the oxyhydroxides were formed by CV in an alkaline medium of 0.10 mol L−1 of NaOH in the potential range from −0.20 V to 1.0 V (100 mV s−1) with successive scans until stabilization of currents. In order to characterize the developed electrodes composites, the surfaces were investigated by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Electrochemical performance of the developed electrodes composites to ethanol electrooxidation was carried out in an alkaline medium of 0.10 mol L−1 of NaOH in the potential range from −0.20 V to 1.0 V (100 mV s−1) by CV. The electrodes were able to induce the electrooxidation of ethanol at a potential of 0.55 V for the electrode made of NiOOH/FeOOH and around of 0.60 V for the electrode modified with NiOOH.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131482226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Coatings on Titanium Surfaces to Improve Their Biological Response","authors":"S. Ferraris, E. Verné, G. Örlygsson, Paulo Tambasco, F. P. Sehn, C. Ng, H. Janusson, G. Banche, V. Allizond, C. Bertea, L. Rimondini, A. Cochis, V. Guarino, A. Varesano, C. Vineis, G. G. D. Confiengo, S. Spriano","doi":"10.3390/ciwc2020-06835","DOIUrl":"https://doi.org/10.3390/ciwc2020-06835","url":null,"abstract":"Biomolecules and extracts from natural products are gaining increasing interest due to their beneficial properties for human health, low toxicity, environmental compatibility and sustainability. In this work, keratin, chitosan and peppermint essential oil have been used for the preparation of coatings on titanium substrates for biomedical implants/devices. All these coatings were obtained from local natural products/byproducts: keratin from discarded wool, chitosan from shrimp shells and peppermint essential oils from a local production. The above cited molecules were selected for their ability to stimulate soft tissue adhesion (keratin), anti-inflammatory activity (chitosan) and antibacterial activity (keratin after metal ion doping, chitosan and mint oil). The coatings were characterized by means of SEM-EDS, FTIR, zeta potential, wettability, tape and scratch tests, and cell and bacteria cultures. The coatings were successfully obtained for all the considered natural substances with good adhesion to the titanium substrates. All the coatings are chemically stable in water and the continuous coatings are mechanically resistant and protective for the metallic substrates. The keratin coatings are hydrophilic while the mint oil and chitosan coatings are hydrophobic; nanofibers, instead of continuous coatings, behave as more hydrophobic. At the physiological pH, the keratin and mint oil coatings are negatively charged when in contact with an aqueous environment, while the chitosan ones are positively charged. The oriented keratin fibers are able to drive fibroblast alignment. The Ag-doped keratin fibers and mint coating show antibacterial properties.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121858844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encapsulated Microbial Propionic Acid as Additive for Texture-Defined Bread","authors":"M. Trif, A. Rusu, A. Schwarze, Malte Bethke, Berta Alvarez Penedo","doi":"10.3390/ciwc2020-06834","DOIUrl":"https://doi.org/10.3390/ciwc2020-06834","url":null,"abstract":"The main goal of the ELBE-NH (Increased effectiveness of lignin-biorefineries by valorization of hydrolysates) project funded by the Federal Ministry of Education and Research (BMBF), Germany, is the utilization of the by-products of lignocellulosic biorefinery as high valuable compounds. One of the targeted compounds selected is propionic acid (PA) (obtained by microbiological conversion of the hydrolysates). PA is particularly suitable for use in industrially produced bread and baked goods, for preservation (antifungal abilities) as free acid or as sodium/calcium salts. Due to its astringent smell and strong acid taste, PA is rarely used in the food industry as a free acid. Our aim is to test the possibility of (a) using encapsulated hydrophilic PA (0.3% w/v) in β-cyclodextrin (β-CD)/maltodextrin blends as the wall materials (19:1 or 17:3% w/v), spray-dried as additives incorporated directly into texture-defined bread products, and (b) incorporating it into polysaccharide-based (e.g., carboxymethylcellulose (2% w/v) or chitosan (2% w/v)) biodegradation-resistant edible film (as carriers of PA antimicrobial agent (1.5–15% w/v)) with/without addition of β-CD (5% w/v) to the film matrix, as packaging material to enhance the safety and shelf life of texture-defined bread products. The benefit of adding β-CD during film preparation consists in the forming of hydrogen bond interactions with PA, resulting in high amounts of PA encapsulation due to the “fully immersed” complexation phenomenon. The texture-defined bread is a bread with a soft, gel-like structure that is easy to swallow and can be consumed without chewing, intended for people suffering from swallowing and chewing disorders. The texture-defined bread will have a high protein content that is up to 15% higher than that of conventional bread and can thus make an important contribution to combating malnutrition.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129745580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of CrAlN Coating Chemical Composition on Soldering Resistance in Contact with Al-Si-Cu Alloy","authors":"P. Terek, Dragan Kukuruzović, L. Kovačević, A. Miletić, V. Terek, B. Škorić, P. Panjan, M. Čekada","doi":"10.3390/ciwc2020-06837","DOIUrl":"https://doi.org/10.3390/ciwc2020-06837","url":null,"abstract":"During the high pressure die casting (HPDC) process the die material is exposed to thermal fatigue, erosion, and corrosion. Corrosion leads to the soldering of cast alloy to tool surfaces which consequently bonds the casting with die material. Besides wear, such a process reduces the casting quality and production efficiency and endangers the tool integrity. Application of thin ceramic coatings on die surfaces reduces the soldering effects and improves the die performance. However, the development of ceramic coatings for these purposes still requires detailed information on the phenomena involved in these processes. In this study, the soldering performance of a complex nanolayer CrAlN coating, with three chemical compositions (high-Cr, balanced Cr:Al, and high-Al content) were evaluated. The cast alloy soldering was evaluated by the detachment test in three configurations. In this test, a simple casting is formed in contact with flat coated surfaces. Upon casting solidification, the formed joint is dismantled, and a force required for this process was recorded. To characterize and quantify the exhibited wear, after the detachment test, surfaces of the coated samples were analyzed by different microscopy techniques. Two forms of wear were detected on investigated samples. Cast alloy soldering processes induced the formation of thin layers of cast alloy on the surfaces of all investigated coatings. Additionally, substrate corrosion through the coating growth defects caused coating layer delamination during the detachment test. The evaluated coatings displayed different behaviors regarding the extent of wear and values of the detachment force. The coating with a balanced CrAlN composition exhibited the best soldering and corrosion resistance and displayed the lowest ejection force. In terms of soldering and corrosion resistance, the high-Al coating outperformed the high-Cr content coating. However, high-Al and high-Cr coating exhibited significantly higher and quite comparable values of detachment force. Based on the quantitative results it was postulated that, besides soldering and substrate corrosion, the casting-coating bonding strength depends also on “pure” sticking effects of cast alloy to coated surfaces.","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131759013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Properties of Thin Film-Covered GaN(0001) Surfaces","authors":"M. Grodzicki","doi":"10.3390/ciwc2020-06833","DOIUrl":"https://doi.org/10.3390/ciwc2020-06833","url":null,"abstract":"In this paper, the surface properties of bare and film-covered gallium nitride (GaN) of the wurtzite form, (0001) oriented are summarized. Thin films of several elements—manganese, nickel, arsenic and antimony—are formed by the physical vapour deposition method. The results of the bare surfaces as well as the thin film/GaN(0001) phase boundaries presented are characterized by X-ray and ultraviolet photoelectron spectroscopies (XPS, UPS). Basic information about electronic properties of GaN(0001) surfaces are shown. Different behaviours of thin films after post-deposition annealing in ultrahigh vacuum conditions, such as surface alloying, subsurface dissolving and desorbing, are found. The metal films form surface alloys with gallium (NiGa, MnGa), while the semi-metal (As, Sb) layers easily evaporate from the GaN(0001) surface. However, the layer in direct contact with the substrate can react with it modifying the surface properties of GaN(0001).","PeriodicalId":315802,"journal":{"name":"Proceedings of 2nd Coatings and Interfaces Web Conference","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126131721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}