{"title":"Knowledge, attitude and practice of traditional eye medicine use among patients attending a tertiary care hospital","authors":"Sriya Sridhar, K. Kartha, Bhogi Rahul, S. Deeja.","doi":"10.4103/ejos.ejos_12_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_12_23","url":null,"abstract":"Purpose This study is intended to assess Knowledge, Attitude and Practice of traditional eye medicine (TEM) use among the patients attending a tertiary care hospital. Settings and design Hospital-Based, Cross-Sectional, Observational Study Methods and material Questionnaire-based assessment of knowledge, attitude and practice regarding TEM use. Results TEM usage was not gender-dependent. The dependent factors were age, marital status, religious beliefs and socio-economic status. Married and lower socio-economic status participants were more prone to seek TEM. Commonly used TEM were, rose water (31.3%), castor oil (17.9%) and Cucumber (14.9%). 35.8% used TEM following foreign body falling into eye. The commonest symptoms for using TEM were redness (73.1%) and watering (59.7%). 71.64% sought TEM following acquaintances’ advice. 43.28% self-medicated. 87.1% did not have any improvement in symptoms following use of TEM. 58.2% consulted an ophthalmologist within 1 week of no improvement in initial symptoms/following complications from TEM usage. Lack of knowledge was the commonest reason quoted for delay in consultations. Conclusions TEM is ineffective, cause ocular complications and can even lead to irreversible blindness. This study gives us an in-depth idea on the need for health education, awareness and reform policies to improve eye health.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"112 - 121"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42209373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autologous platelet rich plasma versus punctal plugs for treatment of moderate to severe dry eye disease","authors":"Hesham A. Enany, Moustafa Salamah, R. Dessouky","doi":"10.4103/ejos.ejos_17_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_17_23","url":null,"abstract":"Aim To compare the outcomes of autologous platelet rich plasma (PRP) eye drops and inferior silicone punctal plugs in the treatment of moderate to severe dry eye disease (DED). Patients and methods This retrospective non-randomized comparative study included 46 patients with bilateral moderate to severe DED during the period from May 2021 to June 2022. They were divided into two groups, Group I: patients treated with autologous PRP eyedrops and Group II: patients treated with an inferior silicone punctal plug. The mean values of ocular surface disease index (OSDI), Schirmer’s test (ST), fluorescein break up time (FBUT), and corneal fluorescein staining (CFS) were calculated for each group at baseline and at 2 weeks, 1 month, and 3 months follow-up. Mean posttreatment values were compared with baseline in each group. Mean values at baseline and at each follow up visit were compared between the two groups. Any complications were recorded. Results Group I included 50 eyes of 25 patients while group II included 42 eyes of 21 patients. Both groups showed statistically significant improvement in all DED parameters posttreatment compared with baseline (P<0.05). There was no statistically significant difference between the two groups regarding DED parameters at baseline and each follow-up visit (P>0.05). Reported complications were spontaneous loss of the plug in 19 (45.2%) eyes and persistent epiphora in 2 (4.8%) eyes in group II. No complications were noted in group I. The difference in complication rates between the two groups was highly significant (P<0.001). Conclusion Both autologous PRP eyedrops and inferior silicone punctal plugs are effective in the treatment of moderate to severe DED. However, inferior silicone punctal plugs are associated with more complications.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"136 - 141"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46742802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toric intraocular lenses versus paired opposite corneal incisions in correction of low-grade astigmatism after phacoemulsification: a comparative study","authors":"W. Ebeid, Noureldin Abozeid","doi":"10.4103/ejos.ejos_102_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_102_22","url":null,"abstract":"Purpose To compare toric intraocular lens (IOL) implantation versus monofocal (Eyhance) IOL with paired corneal incisions for correction of low-grade astigmatism after phacoemulsification. Patients and methods A retrospective comparative study included 30 patients with low-grade astigmatism (−0.75 to −1.50 D) who underwent phacoemulsification: group 1 underwent toric IOL implantation (TECNIS toric) and group 2 underwent enhanced monofocal IOL (TECNIS Eyhance) with paired corneal incision along steep corneal meridian. Best-corrected visual acuity, astigmatism power, and axis were assessed preoperatively and 3 months postoperatively. Vector analysis of astigmatism was done using the Alpins method. Results The mean postoperative residual astigmatism was significantly lower in group 1 versus group 2 (−0.357±0.128 and −0.538±0.225 D, respectively; P=0.015). A significantly higher decrease in astigmatism was noted in group 1 (−0.93±0.18 and −0.38±0.69 D, respectively; P=0.006), with no significant difference in postoperative visual acuity. Paired comparison revealed significant decrease in astigmatism (P<0.0001 in group 1 and 0.04 in group 2) and improvement in uncorrected visual acuity (P<0.0001 for both groups). A significantly higher percentage of success was noted in group 1 (P=0.017), with a higher difference vector in group 2 (P=0.008). Conclusion Our results suggest that both toric IOL and paired corneal incision are efficient methods for postoperative astigmatism correction and achieving postoperative spectacle independence in patients with low-grade astigmatism. Toric IOL is superior in reducing postoperative astigmatism, reflecting more consistent results. The recommendation of IOL type and astigmatism correction should be tailored according to the patient’s requirements, especially with the expanded need for good intermediate vision for everyday tasks that may benefit from enhanced IOLs.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"105 - 111"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46238266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Saigol, NajamNajam Iqbal, S. Akbar, Abdul Rauf, K. Chauhan, F. Ali, AbdulRehman Alvi, Madeeha Naeem, Muhammad Zeeshan
{"title":"Traumatic intraocular foreign bodies: correlation between size and structural damage","authors":"H. Saigol, NajamNajam Iqbal, S. Akbar, Abdul Rauf, K. Chauhan, F. Ali, AbdulRehman Alvi, Madeeha Naeem, Muhammad Zeeshan","doi":"10.4103/ejos.ejos_16_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_16_23","url":null,"abstract":"Background Ophthalmic trauma caused by intraocular foreign bodies (IOFBs) can impact visual prognosis by generating direct ocular structural damage. Factors bearing poor visual prognosis are related to size and velocity of IOFB, location in posterior segment with associated retinal detachment or endophthalmitis. Current study is aimed to evaluate size and location of IOFB and associated ocular structural damage. Methods In this retrospective study done at single tertiary center, patients injured by IOFBs were analyzed between January, 2010 to January, 2021 for ocular structural damage caused by size, velocity and location of impacted IOFB. All were assessed for corneal or scleral perforation and other structural damage due to IOFB. Location, route of retrieval and size of IOFB was measured. Results All 41 eyes were operated for removal of metallic IOFB. Corneal repair was done in 90.2% and scleral repair in 9.8% eyes. Hyphema cleared in 53.6% eyes. Traumatic cataract in 85.4% requiring phacoemulsification, preexisting aphakia (previous surgery) and siderosis was seen in 2.4% eyes. Retinal detachment was present in 14.6% and endophthalmitis in 4.9% eyes. Location of IOFB was on iris and lens in 2.4% each, with 19.5% impacted in retina and 75.6% were isolated in vitreous cavity. Small size IOFB was 58.3%, medium size was 29.3%, large size was 4.9% and very large size was 7.3%. No eye was deformed requiring evisceration of enucleation. Corneal or scleral repair, phacoemulsification, pars plana vitrectomy and intraocular foreign body removal as one stage procedure was done in each case. Intraocular lens implantation was done where sufficient anterior or posterior capsule was present. Conclusion Trauma caused by IOFB is commonly seen at workplace in young male laborers. It usually presents as corneal or scleral perforation, traumatic cataract, endophthalmitis and retinal detachment. Level of structural damage to ocular structures is dependent on the size, velocity and location of IOFB impaction. One stage surgical intervention for wound closure and IOFB should be considered for better surgical prognosis.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"153 - 159"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42064022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr Ali, Y. Serag, Hesham Eltoukhy, Raouf Gaber, Tamer Wasfy
{"title":"Retinal displacement following successful pars plana vitrectomy for rhegmatogenous retinal detachment","authors":"Amr Ali, Y. Serag, Hesham Eltoukhy, Raouf Gaber, Tamer Wasfy","doi":"10.4103/ejos.ejos_114_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_114_22","url":null,"abstract":"Background The appearance of hyperfluorescent lines next to the retinal blood vessels after successful retinal detachment (RD) surgery was explained by the occurrence of retinal displacement. This can attribute to the metamorphopsia experienced by some patients after their surgeries. Patients and methods A prospective interventional study was performed that included 30 eyes of 30 patients with primary rhegmatogenous RD, who had undergone successful RD surgery via pars plana vitrectomy and silicone oil tamponade. The entire patients had preoperative and postoperative fundus autofluorescence and optical coherence tomography. They were followed up for 3 months after surgery with testing of the best-corrected visual acuity and Amsler grid testing. Results The mean age of the included group was 53.7±9.2 years, and 17 (56.7%) patients were males. The most frequent tear site was upper temporal (43.3%), followed by multiple peripheral (23.33%), upper nasal (13.3%), lower temporal (13.3%), and the least was lower nasal (6.7%). Retinal displacement was detected by hyperfluorescent lines adjacent to the retinal blood vessels in the fundus autofluorescence imaging in 16 eyes (53.3% with 95% confidence interval: 36.7–70.0%). Patients with retinal displacement were significantly younger than patients without (P=0.019). The presence of proliferative vitreoretinopathy was significantly related to the occurrence of displacement (P=0.028). Metamorphopsia was significantly more frequent among patients with displacement (P<0.001). Conclusion Retinal displacement had a high possibility to occur after successful repair of primary rhegmatogenous RD. Young patients and patients with proliferative vitreoretinopathy are at a higher risk for displacement.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"79 - 86"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44296825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Ebeid, A. A. Abdel Latif, A. Mousa, Mohammad Akram Awwad
{"title":"Long-term outcome of stab incision glaucoma surgery versus trabeculectomy surgery in the management of primary open angle glaucoma","authors":"W. Ebeid, A. A. Abdel Latif, A. Mousa, Mohammad Akram Awwad","doi":"10.4103/ejos.ejos_95_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_95_22","url":null,"abstract":"Purpose To assess the long-term outcome of Stab incision glaucoma surgery (SIGS) and compare it with subscleral trabeculectomy (SST) in the management of open-angle glaucoma (OAG). Methods Twenty eyes of 20 OAG patients were randomly assigned into group 1: 10 patients underwent SIGS + Mitomycin C (MMC), and group 2: 10 patients underwent SST + MMC. The patients were followed-up over 2 years after surgery. Our outcome measures were: Postoperative intraocular pressure IOP, number of medications used, and postoperative complications. Results Twenty-four months postoperatively, the mean IOP was 13.78±2.05 mmHg in the SIGS group compared with preoperative IOP of 26.33±5.1 mmHg (P <0.001, paired t-test), and 14.38±4.56 mmHg in SST group compared with preoperative IOP of 30.13±7.51 mmHg (P <0.001, paired t-test). No significant differences in mean IOP between groups either preoperatively (P=0.15) or along follow-up (P=0.62 at last visit). The mean IOP drop from baseline was 12.56±5.00 mmHg (46.33±10.50%) in SIGS group and 15.75±8.22 mmHg (49.50±17.95%) in SST group (P=0.26). A significant decrease in the number of glaucoma medications was noted in the SIGSS group (P <0.001), in the SST group, the number decreased but was not statistically significant (P =0.120). Conclusion SIGS is comparable with SST in achieving long-term significant and maintained IOP reduction over up to 2 years, in addition to decreasing the number of antiglaucoma medications postoperatively. SIGS is recommended for surgical management of primary OAG as it has the advantage of being a faster, easier, less traumatic alternative to conventional SST with fewer complications.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"129 - 135"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44920306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Galal, Moumen Seleet, Mohamed Kabeel, Ayman Swar
{"title":"Evaluation of DMEK with secondary IOL implantation in cases of aphakic bullous keratopathy","authors":"A. Galal, Moumen Seleet, Mohamed Kabeel, Ayman Swar","doi":"10.4103/ejos.ejos_19_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_19_23","url":null,"abstract":"Context DMEK is used to treat corneal decompensation. This study focuses on the succcess and outcome of DMEK with and without secondary IOL implantation. Aims The purpose of our work is to evaluate Descemet membrane endothelial keratoplasty (DMEK) with secondary Intraocular lens (IOL) implantation in cases of aphakic bullous keratopathy with insufficient capsular support. Settings and design Pilot study. Methods and material This was a nonrandomized comparative prospective interventional case series where 11 eyes of 11 patients with aphakic bullous keratopathy secondary to complicated cataract surgery underwent DMEK with secondary IOL implantation using modified Yamane technique, and results were compared to 11 eyes of 11 patients underwent DMEK only. Statistical analysis used The statistical analysis was conducted using the Statistical Package for Social Sciences (SPSS 15.0.1 for windows; SPSS Inc, Chicago, IL, 2001). Results Both groups showed a high success rate (81.8%) with rebubbling required in 3 eyes in both groups. Both groups also showed significantly improved BCVA, decreased CCT and a decrease in donor graft ECD. Conclusions DMEK combined with secondary IOL implantation by modified Yamane technique appears to be a feasible method in managing aphakic bullos keratopathy with inadequate capsular support, and results are comparable to DMEK alone.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"142 - 152"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45789788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Posterior segment indications of handheld spectral domain optical coherence tomography in pediatric age group in a tertiary eye center in Egypt","authors":"Gihan Shokier","doi":"10.4103/ejos.ejos_104_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_104_22","url":null,"abstract":"Objective The aim of this study was to detect the posterior segment indications for the use of handheld optical coherence tomography in the pediatric age group. Patients and methods This was a retrospective observational study that included patients who were candidates for handheld spectral domain optical coherence tomography (HH-OCT) imaging for retinal or optic nerve (ON) diseases in Abo Elreesh hospital during the period from June 2018 to June 2022. The image, demographic, and clinical database of the included patients were reviewed. Data were tabulated using Microsoft Excel. Appropriate statistical methods were used to analyze and correlate the obtained data. Results A total of 189 patients were included in this study, comprising 109 (57.7%) male patients. The mean age was 7.2±3.9 (range: 0.2–16 years) years. Overall, 46 (24.3%) patients were less than 5 years of age (i.e. infants and preschool age). Patients who underwent HH-OCT scanning due to retinal causes (i.e. nystagmus, unexplained poor vision, uveitis, Coat’s disease, trauma, and high myopia) were 130 (68.8%) patients, whereas 59 (31.2%) patients were indicated due to ON disease (i.e. primary congenital glaucoma and juvenile open angle glaucoma, optic disc hyperemia, swelling or pallor, and cases of large physiological cupping). Conclusion HH-OCT is a noninvasive feasible image modality for evaluation of retina and ON in infants and young children. The lack of a normative database for retinal nerve fiber layer thickness and ON head parameters in the pediatric age group in the device available in our service is considered a limitation in its use for proper evaluation of different pathologies involving the ON.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"170 - 179"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Tabl, Mahrous Shaheen, Ahmed El Alim Mohamed, M. Tabl
{"title":"Outcomes of air versus sulfur hexafluoride tamponade in primary rhegmatogenous retinal detachment in phakic eyes","authors":"A. Tabl, Mahrous Shaheen, Ahmed El Alim Mohamed, M. Tabl","doi":"10.4103/ejos.ejos_2_23","DOIUrl":"https://doi.org/10.4103/ejos.ejos_2_23","url":null,"abstract":"Purpose To evaluate the outcomes of using air versus sulfur hexafluoride (SF6) gas tamponade in management of primary rhegmatogenous retinal detachment (RRD). Study design Retrospective case-series comparative study. Patients and methods We collected data from 120 patients in three tertiary university hospitals, that were diagnosed as primary RRD due to upper retinal break in the period from January 2021 to November 2022 and had undergone 23-G lens-sparing pars-plana vitrectomy with either air tamponade (Air group) or SF6 gas tamponade (SF6 group) and were followed up for 6 months. We analyzed the final visual outcomes between both groups. Results The mean age of the studied patients was 51±13 years (Air group=60 eyes, SF6 group=60 eyes). The mean axial length in Air group was 26.59±1.84 mm, the mean axial length was 26.46±1.49 mm in SF6 group. Best-corrected visual acuity was improved in both groups at the sixth month. In Air group 18.33% had recurrent RRD, while 10% in SF6 group. No significant difference regarding metamorphopsia was reported. Higher rate for cataract progression was noted among SF6 group. Conclusions Both Air and SF6 gas showed favorable results regarding the final visual outcome. Air is a less expensive tamponade with less timing for postoperative-prone positioning. Cataract progression was higher among SF6 group, however, the incidence of recurrent RRD was lower among SF6 group. Missed break was the primary cause for failed retinal reattachment.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"87 - 92"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41977622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the outcome of limited protocol Ranibizumab injection in naïve choroidal neovascular membranes secondary to pathological myopia versus age-related macular degeneration","authors":"S. Fawzy, Mohammed Al-Tawab, Z. Ismail, W. Ebeid","doi":"10.4103/ejos.ejos_113_22","DOIUrl":"https://doi.org/10.4103/ejos.ejos_113_22","url":null,"abstract":"Aim We aimed to compare the anatomical and visual response of newly diagnosed choroidal neovascularization (CNV) secondary to pathological myopia or age-related macular degeneration with relatively poor initial vision to treatment with three intravitreal injections of ranibizumab. Patients and methods This prospective, comparative study included 29 eyes of 29 patients newly diagnosed with subfoveal active CNV, either secondary to age-related macular degeneration (AMD-CNV, 15 eyes) or to pathological myopia, that is, myopic CNV (MCNV, 14 eyes). All patients had an initial best-corrected visual acuity (BCVA) equal to or worse than 1.00 Log Mar. Patients received three intravitreal injections of 0.50 mg ranibizumab on a monthly basis. Patients were evaluated before injections and one month after each injection for BCVA and optical coherence tomography-measured retinal parameters: central macular thickness, total volume, and average thickness (AT). Amsler’s chart was used to detect scotomas and metamorphopsias. Results One month after the three injections, a significant improvement was noted in the two groups in central macular thickness, total volume, and AT. The improvement was significantly better in AT of the AMD group. The mean BCVA improved significantly in the AMD group only as patients either improved or remained stationary, whereas in the MCNV group, 21% of patients deteriorated, which affected the significance of the overall mean of improvement (P=0.7823); the difference in the overall mean was insignificant. Despite that, almost half of the patients in each group had their visual acuity improved by an average of 9.5 letters in AMD and 10.7 in MCNV. Conclusion Naïve AMD-CNV and MCNV of initially poor VA can get significant improvement in all optical coherence tomography-measured retinal parameters following a three-injection course of ranibizumab on a monthly basis. VA improvement is more predictable in AMD, as no patients deteriorated after the injections, yet the overall difference in VA improvement between groups was insignificant.","PeriodicalId":31572,"journal":{"name":"Journal of the Egyptian Ophthalmological Society","volume":"116 1","pages":"99 - 104"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70723396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}