Revista Medica del Hospital General de Mexico最新文献

{"title":"Intussusception secondary to Meckel's diverticulum in a 3-month-old girl. Case report","authors":"I. Camacho-Guerrero ,&nbsp;L. Ramírez-Patiño","doi":"10.1016/j.hgmx.2016.05.011","DOIUrl":"10.1016/j.hgmx.2016.05.011","url":null,"abstract":"<div><p>A 3-month-old female patient is presented, with ileo-ileal intussusception secondary to Meckel's diverticulum. The patient underwent emergency surgery due to a diagnosis of intestinal obstruction secondary to intussusception.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 ","pages":"Pages 33-35"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.05.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54294570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-review. Liver transplantation for hepatocellular carcinoma","authors":"V. Visag-Castillo","doi":"10.1016/j.hgmx.2016.10.003","DOIUrl":"10.1016/j.hgmx.2016.10.003","url":null,"abstract":"<div><p>Liver transplantation is the gold standard treatment for end stage liver disease, including patients with cirrhosis and hepatocarcinoma falling within Milan criteria. HCC is the sixth most common cancer around the world, and leading cause of death among cirrhotic patients. Diagnosis is based upon radiological characteristics and rarely biopsy results; the Barcelona Clinic Liver Cancer staging system is the most used guideline for treatment. With several treatment options available transplantation and resection continue to be the major curative therapeutic option for this patients. However treatment must be individualized to each patient to improve recurrences and outcomes. The aim of this paper is to review the present role of liver transplantation in the management of hepatocarcinoma.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 2","pages":"Pages 97-101"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54295868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelioid osteoblastoma or aggressive osteoblastoma of the astragalus. Presentation of a case and revision of clinical and pathological symptoms","authors":"A. Alcántara-Vázquez ,&nbsp;S. Castillo-Guitarrero ,&nbsp;J.A. Enríquez-Castro ,&nbsp;M. Hernández-González","doi":"10.1016/j.hgmx.2017.05.005","DOIUrl":"10.1016/j.hgmx.2017.05.005","url":null,"abstract":"<div><p>This is the case of a 58 year-old man with a painful tumour in his right ankle, resulting from a long development. An osteolytic injury was found in an X-ray, formed by bone or osteoid trabeculae surrounded by epithelioid osteoblasts and amongst these cells there were osteoclast-type multinucleated cells. The histogenesis of the tumour, the differential diagnosis and the treatment modalities are reported.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 2","pages":"Pages 93-96"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44413154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a nutritional intervention in the reduction of gastrointestinal toxicity during teletherapy in women with gynaecological tumours","authors":"J.H. Soto-Lugo ,&nbsp;M.A. Souto-Del-Bosque ,&nbsp;C.A. Vázquez Martínez","doi":"10.1016/j.hgmx.2017.03.005","DOIUrl":"10.1016/j.hgmx.2017.03.005","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate whether nutritional intervention through a diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols reduces acute gastrointestinal toxicity by pelvic teletherapy in patients with gynaecological tumours.</p></div><div><h3>Material and methods</h3><p>A prospective unicentric randomised clinical trial comparing patients on a diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols versus a standard Mexican diet, designed to detect a decrease from 80% of grade 1–2 acute gastrointestinal toxicity in the normal diet group versus a 25% of acute gastrointestinal toxicity grade 1–2 in patients assigned to a diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols.</p></div><div><h3>Results</h3><p>Thirteen patients were recruited per group, with a higher gastrointestinal toxicity in the normal diet group, grade 1–2 (85% vs 77%) and 3 (23% vs 0%) compared to the diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols (<em>p</em> 0.16). The diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols group had a lower symptom score at the end of treatment in the quality of life questionnaire of patients with cervical cancer (1.41 vs 1.85, <em>p</em> 0.01) and a lower mean deterioration in performance status (0.61 of 0.5 vs 0.23 of 0.43, <em>p</em> 0.049). 85% of the patients had an excellent attachment to the diet. No significant factors associated with the presence of grade 3 gastrointestinal toxicity were found.</p></div><div><h3>Conclusion</h3><p>The implementation of a diet low in oligosaccharides, disaccharides, monosaccharides and fermentable polyols during treatment with pelvic teletherapy is a low cost and high attachment intervention, which decreases the deterioration of functional status and symptomatology at the end of treatment in patients with cervical cancer.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 7-14"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43970550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative treatment between sitagliptin vs. metformin, alone or in combination, in patients with polycystic ovary syndrome. A clinical entity at high risk for developing diabetes mellitus and gestational diabetes: A pilot study","authors":"J.C. Paredes Palma ,&nbsp;E. López Byhen ,&nbsp;L. Ibáñez ,&nbsp;L. Balladares Macedo ,&nbsp;C. Paredes Palma ,&nbsp;C. Ramírez Velázquez","doi":"10.1016/j.hgmx.2017.03.001","DOIUrl":"10.1016/j.hgmx.2017.03.001","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the efficacy of sitagliptin alone or in combination with metformin in women with polycystic ovary in terms of ovarian cyclicity, fertility and cardiometabolic profile compared to metformin alone.</p></div><div><h3>Rationale</h3><p>polycystic ovarian syndrome (PCOS) affects a percentage of 5–10% of women of reproductive age worldwide and has a prevalence of 6.6% (95% CI: 2.3–10.9%) in Mexican women and most common cause of infertility in developed countries.</p><p>Treatment with insulin sensitizing drugs (metformin and pioglitazone) has been shown to improve menstrual cyclicity and fertility in the metabolic profile with polycystic ovarian patients. Incretins and DPP-4 inhibitors have been shown to enhance pancreatic β cell activity, increasing weight loss by its anorexic effect and resulting in an adequate weight control and improved fertility.</p><p>Previous evidence has compared the effect of exenatide and alone or in combination with metformin in the treatment of PCOS, in this article we will compare sitagliptin and metformin alone or in combination.</p></div><div><h3>Study design</h3><p>Blind, controlled and randomized clinical trial.</p></div><div><h3>Patients</h3><p>Women between 18 and 40 years of age, with a BMI &gt;20 and diagnosed with PCOS with the Rotterdam criteria.</p></div><div><h3>Results</h3><p>In the normalized index of menstruations it was found that there was a statistically significant intragroup increase in each one of the treatments. With a higher percentage of change, that of metformin with 80%, followed by that of sitagliptin with 65% and then COMBO with 30%. No statistically significant differences were found between treatment groups.</p></div><div><h3>Conclusion</h3><p>Therapeutic effect of sitagliptin was observed in patients with PCOS comparable to metformin and the combination of metformin-sitagliptin is more effective in terms of ovulation than the other two treatments alone.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 15-26"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43873583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splenectomy in abdominal trauma in the General Hospital of Balbuena from January 2010 to December 2014","authors":"A.D. Jiménez-García ,&nbsp;L.E. Cardiel-Marmolejo ,&nbsp;C.G. Cerón-García ,&nbsp;S. Durán-Ortiz","doi":"10.1016/j.hgmx.2016.11.002","DOIUrl":"10.1016/j.hgmx.2016.11.002","url":null,"abstract":"<div><h3>Background</h3><p>In abdominal trauma, spleen is the most commonly injured abdominal organ. Spleen injuries can be managed in three modes: splenectomy, nonoperative management and splenorrhaphy, all based on the scale of severity of splenic injury of the American Association of Trauma.</p></div><div><h3>Objective</h3><p>To determine the incidence of splenic injury and management at the Balbuena General Hospital according to the severity scale of the American Association of Trauma.</p></div><div><h3>Materials and methods</h3><p>An observational, descriptive and retrospective study was conducted in patients attending at the General Hospital Balbuena with splenic injury in abdominal trauma, in the period from January 2010 to December 2014, excluding all patients under 18 years old, with splenic injury.</p></div><div><h3>Results</h3><p>Were found a total of 59 cases of patients with splenic injury. Of the total population 84.7% splenectomy was performed, 85% of cases were male and 15% female. The group with the highest number of cases of splenic lesion was found in the range from 20 to 29 years, representing 28.81%. Of the study population 55.93% are blunt abdominal trauma.</p></div><div><h3>Conclusion</h3><p>The blunt abdominal trauma remains one of the most common causes of splenic injury. The clinical status of the patient, the degree of hypovolemic shock, the degree of splenic injury and associated injuries are the guidelines on the type of approach and treatment in patients with splenic injury. Today the blunt abdominal trauma with severe splenic injury is the most frequent indication for splenectomy.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 35-40"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.11.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54296888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The maximum expression of hypoxia and hypoventilation: Acute respiratory distress syndrome","authors":"M.A. Amezcua-Gutiérrez ,&nbsp;J.O. Montoya-Rojo ,&nbsp;J.A. Castañón-González ,&nbsp;S.E. Zamora-Gómez ,&nbsp;L.A. Gorordo-Delsol ,&nbsp;G.D. Hernández-López ,&nbsp;O.R. Pérez-Nieto ,&nbsp;A. Cabanillas-Cervantes ,&nbsp;J. Garduño-López ,&nbsp;I.M. Lima-Lucero ,&nbsp;S. Cruz-Montesinos","doi":"10.1016/j.hgmx.2017.03.003","DOIUrl":"10.1016/j.hgmx.2017.03.003","url":null,"abstract":"<div><p>Over the past 50 years, it has been developed a well-defined conceptual model of ADRS, characterised by a diffuse alveolar damage caused by an injury in the pulmonary endothelium and alveolar epithelium. It is defined as a sudden respiratory failure, with the presence of bilateral opacities in imaging studies (typically in chest radiographies and computed tomographies), pulmonary oedema not fully explained by cardiac failure or liquid overload and hypoxaemia with a PaO₂/FiO₂ <!-->&lt;<!--> <!-->300<!--> <!-->mmHg with a positive end expiratory pressure (PEEP)<!--> <!-->&gt;<!--> <!-->5<!--> <!-->cm H₂O. Its development has been described in the framework of numerous diseases and injuries, which are widely classified in pulmonary and extrapulmonary conditions; being pneumonia the most common risk factor to the development of this syndrome. Despite the advances in the management and prevention of ARDS, medical physicians are facing complications secondary to the treatment used, being the most characteristic ventilator induced lung injury, which not only increases lung damage but also has extrapulmonary repercussions, such as cardiac alterations.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 47-58"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48539749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transitory electrocardiographic abnormalities following blunt cardiac trauma: Case report and literature review","authors":"J. Valle-Alonso ,&nbsp;F.J. Fonseca del Pozo ,&nbsp;M.A. Aguayo-López ,&nbsp;J. Pedraza ,&nbsp;F.J. Rosa-Úbeda ,&nbsp;A. López- Sánchez","doi":"10.1016/j.hgmx.2016.06.003","DOIUrl":"10.1016/j.hgmx.2016.06.003","url":null,"abstract":"<div><p>Blunt cardiac trauma (BCT) includes a number of diseases ranging from clinically silent arrhythmias to lethal cardiac wall rupture. The most common form is “cardiac contusion”, which is currently under debate. The absence of a clear definition and the lack of diagnostic tests of choice make diagnosing cardiac contusion difficult. We present the case report of a healthy young patient who went to the emergency department with electrocardiogram changes following blunt chest trauma, and review the current literature on the subject.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 41-46"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54294604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytological diagnosis of cervical adenocarcinoma and cytohistological agreement at General Hospital of Mexico “Dr. Eduardo Liceaga”","authors":"Y.U. Zamora Guerra ,&nbsp;S. Córdova Ramírez","doi":"10.1016/j.hgmx.2017.03.007","DOIUrl":"10.1016/j.hgmx.2017.03.007","url":null,"abstract":"<div><h3>Background</h3><p>Cervical adenocarcinoma has increased in recent years, and there is no early form of detection other than cervicovaginal cytology, which has a high sensitivity and specificity for squamous lesions, but poor sensitivity in detecting adenocarcinoma. In our hospital, previous research on this topic has not been done.</p></div><div><h3>Objective</h3><p>To know the number of cases of cervical adenocarcinoma diagnosed by cervicovaginal cytology, as well as the degree of discordance by histopathological study.</p></div><div><h3>Material and method</h3><p>A cytohistological correlation was performed in 82 of 120 cases diagnosed as “adenocarcinoma” in cervical cytology at the General Hospital of Mexico “Dr. Eduardo Liceaga “in the period from 2007 to 2016.</p></div><div><h3>Results</h3><p>82 cases with biopsy study by the Surgical Pathology service were categorised into 25 cases (30.48%) of adenocarcinoma of the cervix, 21 (25.60%) of adenocarcinoma of the endometrium, 17 (20.73%) squamous lesions, 7 (8.53%) changes by metaplasia or cervicitis, 3 (3.65%) mixed Müllerian tumours, and 1 case (1.21%) of the following: papillary cystadenocarcinoma of the ovary, colonic mestastasic adenocarcinoma, endometrial hyperplasia, normal endometrium and polypoid adenomyoma. Four cases (4.87%) did not have an adequate biopsy at the first time, and the diagnosis could not be corroborated.</p></div><div><h3>Conclusions</h3><p>Cervicovaginal cytology is a useful tool for the detection of glandular lesions, however, it is difficult to discriminate on origin only through morphology, since many other entities overlap.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43008174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of cancer testis antigens in patients with Hodgkin's lymphoma and their clinical correlation","authors":"L.M. Hodgson Reyes ,&nbsp;I. Olarte Carrillo ,&nbsp;C.O. Ramos Peñafiel ,&nbsp;A. Martínez Tovar ,&nbsp;E. Gallardo ,&nbsp;H. Castellanos Sinco ,&nbsp;J. Collazo Jaloma","doi":"10.1016/j.hgmx.2016.11.005","DOIUrl":"10.1016/j.hgmx.2016.11.005","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the frequency of expression of cancer testis antigens and their clinical correlation in patients with Hodgkin lymphoma.</p></div><div><h3>Methodology of the study</h3><p>In this analytical, experimental and ambispective study, the MAGE A-3 and NY-ESO-1 antigen expression was correlated with clinical prognostic variables such as clinical stage, response to treatment, and relapse, in a total of 70 patients diagnosed with Hodgkin's lymphoma at the Hodgkin's Lymphoma Clinic of the General Hospital of Mexico “Dr. Eduardo Liceaga”, from December 2000 to December 2015. Twenty-four patients were evaluated using RT-PCR, following extraction of RNA, to detect MAGE-A3 and NY-ESO1 expression. Cellular RNA was extracted from frozen tissue and controls using trizol (Life Technologies, Paisley, UK). 1<!--> <!-->μg of RNA was used for cDNA synthesis by M-MLV reverse transcriptase (Life technologies, Paisley, UK).</p></div><div><h3>Results</h3><p>We studied 24 patients with a median age of 28 years, a minimum age of 16 years and a maximum age of 48 years, mostly male. 50% of patients presented complete response to the first line of treatment and 27% of patients presented relapse, 37.5% in relation to the expression of MAGE-A3. Expression of the NY-ESO-1 gene was not found in the study group. Twelve percent of patients died during the study, 8.33% of whom were also positive for MAGE-A3 (<em>p</em> <!-->=<!--> <!-->0.264.95% CI). No significant correlation was found between MAGE-A3 expression and major clinical prognostic variables.</p></div><div><h3>Conclusion</h3><p>Although the expression of MAGE-A3 in the study group was 37.5% (higher than reported in international studies), we found no correlation with the main clinical prognostics variables. Considering that the expression of MAGE-A3 in the cases studied does not confer prognostic value, making it impossible to use as a prognostic tool in peripheral blood, we are leaving the doors open to continue with this line of research, possibly increasing the number of patients as well as prolonging the follow-up time.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 1","pages":"Pages 27-34"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54297038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}