Hamid Khederlou, Vida Ebrahimi, Ahmadreza Rasouli, M. Mehrpooya
{"title":"A Comparison of the Prognosis of SARS-CoV-2 Viral Infection in Patients with and Without Underlying Heart Disease","authors":"Hamid Khederlou, Vida Ebrahimi, Ahmadreza Rasouli, M. Mehrpooya","doi":"10.5812/intjcardiovascpract-132258","DOIUrl":"https://doi.org/10.5812/intjcardiovascpract-132258","url":null,"abstract":"Background: Since December 2019, a pneumonia outbreak has spread through a viral infection. Originally, the virus pathogen was termed SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). SARS-CoV-2 can cause severe and life-threatening problems. Objectives: The purpose of this study was to describe the prognostic comparison of SARS-CoV-2 viral infection in patients with and without underlying heart disease in our center. Methods: A total of 400 Iranian adult patients with COVID-19 enrolled in this descriptive-analytical research. The study population was categorized into 4 groups: (1) no underlying disorder, (2) only cardiovascular complication, (3) only non-cardiovascular disease (CVD), and (4) cardiovascular and non-cardiovascular complications. The prognosis was adjudicated based on underlying diseases. Anthropometric details were also gathered. Finally, the data were analyzed using SPSS version 25. Results: The mortality rate was almost 4.17 times more in patients suffering from both cardiovascular and non-cardiovascular complications compared with the first group having no underlying disorders. This rate was 3.98 times more than the baseline in patients complicated with CVD alone. Based on a logistic regression model, COVID-19 prognosis was associated with age, underlying disorder type, length of hospitalization, the requirement for the intensive care unit (ICU), length of stay in ICU, the need for intubation, reservoir bag-mask requirement, and some of the life-threatening complications such as pneumonia and sepsis. Conclusions: Cardiovascular underlying disorders (such as myocarditis and deep vein thrombosis) are likely to be linked to the prognosis of COVID-19.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79073098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Tabaghi, E. Mahmoudi, M. Namazi, I. Khaheshi, M. Akbarzadeh
{"title":"Clinical Predictors of Successful Anti-tachycardia Pacing for Ventricular Arrhythmia Termination","authors":"S. Tabaghi, E. Mahmoudi, M. Namazi, I. Khaheshi, M. Akbarzadeh","doi":"10.5812/intjcardiovascpract-131817","DOIUrl":"https://doi.org/10.5812/intjcardiovascpract-131817","url":null,"abstract":"Background: Anti-tachycardia pacing (ATP) is a fast and safe method for terminating ventricular tachycardia (VT). Implantable cardioverter defibrillator (ICD) shocks are unpleasant, stressful experiences that have been associated with higher mortality rates than ATP. Determining the factors enhancing the efficacy of ATP therapies can minimize the appropriate ICD shocks. Objectives: In this study, we investigated the factors anticipating the success rate of ATP. Methods: This descriptive cross-sectional study was carried out among 60 patients referring to our center for regular ICD device analysis. These patients had at least one episode of appropriate ATP therapy in their analysis. The VT morphologic characteristics were obtained from stored far-field intracardiac electrogram (EGM). The VT episodes and native QRS were classified into non-Q or Q categories based on their EGM morphologies. Results: ATP was successful in 38 (63.3%) cases. Age, sex, history of ischemic heart disease and diabetes, type of device and cardiomyopathy (ischemic or dilated), antiarrhythmic drugs, left ventricular ejection fraction, and EGM characteristics did not predict ATP success. Conclusions: It seems that neither the demographic factors nor the morphologic characteristics of VT EGMs can predict the efficacy of ATP therapy.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78702819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Methadone-Induced QT Interval Prolongation and Torsades de Pointes","authors":"S. Tabaghi, M. Akbarzadeh","doi":"10.5812/intjcardiovascpract-130693","DOIUrl":"https://doi.org/10.5812/intjcardiovascpract-130693","url":null,"abstract":": The most common cause of acquired long QT syndrome in patients without physiological and structural cardiovascular disease is the use of medications. Chronic high-dose methadone usage can cause prolongation of QT interval that may provoke the life-threatening arrhythmia Torsades de Pointes. In this study, we present a 41-year-old man with chronic high-dose methadone usage who developed Torsades de Pointes triggered by short-coupled premature ventricular contraction.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83423316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daozheng Huang, F. Song, Weidai Zhang, Hua Ma, Xingtao Lin, Tiehe Qin, Shouhong Wang
{"title":"Fulminant Myocarditis Complicated with Immune Checkpoint Inhibitor in Patients with Thymoma: Report of Three Cases and Literature Review","authors":"Daozheng Huang, F. Song, Weidai Zhang, Hua Ma, Xingtao Lin, Tiehe Qin, Shouhong Wang","doi":"10.21203/rs.3.rs-707559/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-707559/v1","url":null,"abstract":"\u0000 IntroductionImmune checkpoint inhibitors (ICIs) prevent the immune escape of tumor cells, which is beneficial to immune cells such as T lymphocytes to continuously monitor and kill tumor cells, and ultimately play an effective role in anti-tumor. ICI-associated myocarditis (irMyositis) was rarely reported, but its onset appeared latent, rapidly developed, and lethal, which has gradually attracted the attention of clinicians. Case ReportWe reported cases of fulminant myocarditis in 3 patients with thymoma who were treated with pembrolizumab, one of the programmed cell death protein 1 inhibitors (PD-1 inhibitors).Management & OutcomeThe 3 patients were treated with methylprednisolone, immunoglobulin. Temporary pacemaker implantation was performed when case 1 suffered atrioventricular dissociation and ventricular escape. Cardioversion was performed in case 2 for the onset of ventricular tachycardia. In case 3, Extra-Corporeal Membrane Oxygenation was implemented. Unfortunately, the heart function did not improve and was succeeded by multiple organ failure in all 3 cases. The family withdrew treatment and led to lethal outcomes.DiscussionAlthough ICIs have achieved encouraging results in anti-tumor, their adverse reactions cannot be ignored. Patients with thymoma are more prone to autoimmune reactions which are needed more attention1. We reported cases of immunotherapy-associated myocarditis in patients with previous PM, showing the clinical and pathological features in the specific populations.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77421958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Bozorgmehr, Mehdi Pishgahi, P. Mohaghegh, M. Bayat, Parastou Khodadadi, Ahmadreza Ghafori
{"title":"Prevalence of Non-Thromboembolic Incidental Findings on Computed Tomography-Pulmonary Angiography for Pulmonary","authors":"R. Bozorgmehr, Mehdi Pishgahi, P. Mohaghegh, M. Bayat, Parastou Khodadadi, Ahmadreza Ghafori","doi":"10.29252/26716","DOIUrl":"https://doi.org/10.29252/26716","url":null,"abstract":"Introduction: Computed Tomography-Pulmonary Angiography (CTPA) is a noninvasive imaging modality for direct diagnosis of pulmonary thromboembolism. The potential advantage of CTPA is possible alternative and incidental findings in cases that PTE is ruled out. This study was performed to determine the prevalence of incidental findings in CTPA in patients suspected to have PTE. Methods: This cross-sectional retrospective study was performed in patients with suspected PTE admitted to Shohada-e-Tajrish Hospital in 2014 and 2015 and underwent CTPA for final diagnosis. Incidental findings in CTPA and associated clinical symptoms were assessed. Results: According to CTPA performed in 188 patients, PTE was diagnosed in 61 cases (32.4%). Prevalence of incidental abnormal findings in the two groups with and without PTE were 93.7% and 90.9%, respectively. The most common incidental finding was pleural effusion (42%). There was no significant association between clinical symptoms and incidental findings in CTPA in patients with suspected pulmonary embolism (P > 0.05). The only significant finding was association between lung mass and tachypnea (P=0.007). Conclusion: In patients with primary clinical symptoms of suspected pulmonary embolism, in most cases there was a wide range of incidental findings and simultaneous pathologies in CTPA mimicking the primary symptoms of pulmonary embolism. However, in this study there was no significant association between clinical symptoms and incidental findings. Determination of definite indications of CTPA in patients with suspected pulmonary embolism is necessary.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80783614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parisa Pourroostaei Ardakani, A. Ramezani, Z. Piravar, N. Asgharimoghadam, R. Behzadi, M. J. Fesharaki
{"title":"Different Polymorphisms of Placental Growth Factor (PLGF) Gene in Iranian Women's Population with Pre-eclampsia","authors":"Parisa Pourroostaei Ardakani, A. Ramezani, Z. Piravar, N. Asgharimoghadam, R. Behzadi, M. J. Fesharaki","doi":"10.29252/IJCP-26694","DOIUrl":"https://doi.org/10.29252/IJCP-26694","url":null,"abstract":"Introduction: Preeclampsia is a complication affecting pregnant women worldwide, which leads to maternal and fetal morbidity and mortality. Due to the importance of mutations in the PLGF (Placental Growth Factor) gene and the association with the incidence of preeclampsia, this study aimed to evaluate the association of polymorphisms of the PLGF gene with the prevalence of preeclampsia in Iranian women. Methods: Fifty pregnant women with pre-eclampsia diagnosis and 50 healthy pregnant women for determination of genotypes rs1464547123, rs12411, rs1399853427, and rs1312670436 were evaluated using the Sanger sequencing method. Results: There was no significant difference in the frequency of alleles of rs1464547123, rs1399853427 and rs1312670436 polymorphisms between case and control groups (P > 0.05), but the rate of recessive allele A in rs12411 polymorphism was significantly higher in the case group than in the control group (case = 24%, control = 8%, P-Value = 0.04), while the frequency of the allele T in the control group was higher than that of the patient group (case = 76%, control = 92%, P-Value = 0.04) The frequency of AT genotype in the patient group was a none significantly higher than the control group (case = 8%, control = 4%, P-Value = 0.1) and the frequency of AA genotypes in the case group was none significantly higher than that of the control group (case = 16%, control = 4%, P-Value = 0.1). Conclusions: The results revealed that polymorphism rs12411 of the gene encoding PLGF has a significant difference among individuals with and without pre-eclampsia and can affect the incidence of pre-eclampsia among Iranian women.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80348386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roxana Sadeghi, Naser Kachoueian, Zohreh Maghsoomi, Mohammad Sistanizad, Zahra Soroureddin, M. Akbarzadeh
{"title":"Cardiogenic Shock Following Acute Myocardial Infarction: A Retrospective Observational Study","authors":"Roxana Sadeghi, Naser Kachoueian, Zohreh Maghsoomi, Mohammad Sistanizad, Zahra Soroureddin, M. Akbarzadeh","doi":"10.29252/IJCP-27631","DOIUrl":"https://doi.org/10.29252/IJCP-27631","url":null,"abstract":"Introduction: Cardiogenic shock is a sudden complication that occurs in 5 to 10% of patients with acute myocardial infarction. According to statistics, mortality and morbidity from this event, despite all hospital care, are approximately 70-80%. Methods : This study was conducted over three years (2012 to 2014) in 28 cases of acute myocardial infarction, which was complicated by cardiovascular shock, before or after admission. We compared the outcomes of patients according to the treatment strategy, thrombolytic therapy, primary percutaneous coronary intervention (PCI), or other medical stabilization. The 30-day follow-up was the first endpoint, and the 3- month follow up was the second endpoint of the study. Results : 28 patients with cardiogenic shock included in this study. The mean (± SD) age of the patients was 62.99 ± 13.99 years. The median time to the onset of shock was 648.75 ± 1393.58 minutes after infarction. Most of the patients who underwent coronary angiography had 3-vessel or left main involvement. Two patients missed in follow up and five (80%) patients who received thrombolytic therapy passed away. Nine (100%) patients in the medical stabilization group and six patients (50%) underwent primary PCI group passed away too. The mortality in the primary PCI group was significantly lower than the other groups (P = 0.04). Conclusion: Although cardiogenic shock is a potential risk of early death, it is important that the thrombolytic in these patients doesn't increase survival and the primary PCI is more effective than thrombolytic agents.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91244853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Talhi, Monia Elmourid, A. Maaroufi, Z. Qechchar, S. Arous, E. Bennouna, L. Azzouzi, R. Habbal
{"title":"Acute Myocarditis Mimicking an Acute Coronary Syndrome: Case Report and Mini-Review of the Literature","authors":"F. Talhi, Monia Elmourid, A. Maaroufi, Z. Qechchar, S. Arous, E. Bennouna, L. Azzouzi, R. Habbal","doi":"10.29252/IJCP_27070","DOIUrl":"https://doi.org/10.29252/IJCP_27070","url":null,"abstract":"Acute myocarditis is often a challenging diagnosis due to a lack of specific clinical or paraclinical signs. It can be presented by a severe chest pain and localized ST elevation on Electrocardiogram, in rare cases, misleading the diagnosis towards acute coronary syndrome. After routine coronary angiography, a cardiac magnetic resonance imaging is imposed to correct the diagnosis towards acute myocarditis. We report the observation of a 19 year-old Moroccan male admitted to the cardiology department of IBN ROCHD University hospital of Casablanca, for acute myocarditis misdiagnosed initially as an acute myocardial infarction ST elevation and confirmed by cardiac magnetic resonance imaging.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81313867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ganganpalli Dattaprasad, U. Chandra, S. Vishwakarma, V. Pandey, S. Dubey
{"title":"Pulmonary Capillary Hemangiomatosis: A Rare Cause of Pulmonary Arterial Hypertension, Presenting as Supraventricular Tachycardia","authors":"Ganganpalli Dattaprasad, U. Chandra, S. Vishwakarma, V. Pandey, S. Dubey","doi":"10.29252/IJCP-27360","DOIUrl":"https://doi.org/10.29252/IJCP-27360","url":null,"abstract":"With a prevalence of less than 1/million, Pulmonary Capillary Hemangiomatosis is a rare disorder of capillary proliferation in the alveolar septae leading to pulmonary arterial hypertension and mimics pulmonary veno-occlusive disease.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84518869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Ezzati, N. Abbasi, H. Namdar, Naser Khezerlou Aghdam, T. H. Nosratabad, Ali Shiri, B. Sadeghi, M. Salehi
{"title":"The Relationship between Sleep Quality and Happiness in Men with Coronary Artery Disease","authors":"D. Ezzati, N. Abbasi, H. Namdar, Naser Khezerlou Aghdam, T. H. Nosratabad, Ali Shiri, B. Sadeghi, M. Salehi","doi":"10.29252/ijcp-28143","DOIUrl":"https://doi.org/10.29252/ijcp-28143","url":null,"abstract":"Introduction: Good sleep quality has positive effects on happiness, and being unhappy is significantly affect adverse cardiac outcomes. This study aimed to study the relationships between sleep quality and satisfaction in male coronary patients. Methods: One hundred male coronary patients that having been referred to Madani Heart Hospital, Tabriz, Iran, completed the Pittsburgh Sleep Quality Index (PSQI) and Oxford Happiness Questionnaire (OHQ). All participants were selected by purposive sampling (aged 37 to 67 years). Results: There was a significant negative association between happiness with sleep disturbances and the use of sleeping medication in coronary patients. Conclusion: This study showed that sleep quality in coronary patients has an association with their happiness. Therefore, the quality of sleep in these patients can be given more consideration by community health care providers.","PeriodicalId":31436,"journal":{"name":"International Journal of Cardiovascular Practice","volume":"2014 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86503179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}