Journal of Clinical and Preventive Cardiology最新文献

{"title":"Incidentally detected “tram track forearm arteries” in an elderly","authors":"G. Divani, Shivank Gupta, A. Ahmed","doi":"10.4103/jcpc.jcpc_32_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_32_21","url":null,"abstract":"","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"150 - 150"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48360881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucella endocarditis of bicuspid aortic valve","authors":"S. Devi, Nilanjan Kar, Debananda Sahoo, Tutan Das, D. Acharya, Debasish Das","doi":"10.4103/jcpc.jcpc_29_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_29_21","url":null,"abstract":"We present a rare case of Brucella endocarditis in a case of the bicuspid aortic valve in a 51-year-old male presenting with pyrexia of unknown origin for the last 2 months. Infective endocarditis caused by Brucella melitensis is rare to encounter in routine clinical practice. Although we routinely think of Mycoplasma, Legionella, and Coxiella in the cases of blood culture-negative endocarditis, one should think of Brucella melitensis and Scrub typhus as the last arrow to reach the final etiology of infective endocarditis in the subset of diseased aortic or mitral valve. We successfully treated the patient with a combined regimen of rifampicin, gentamicin, and doxycycline therapy; during follow-up, the vegetation of the aortic valve was shrunken and calcified and the patient was asymptomatic.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"147 - 149"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42181590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and concerns of secondary prophylaxis for rheumatic heart disease with benzathine penicillin: A tertiary care cardiac centre experience","authors":"P. Bhat, Arun B. Shivashankarappa, Radha Krishnappa, M. Nanjappa","doi":"10.4103/jcpc.jcpc_23_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_23_21","url":null,"abstract":"Background: Rheumatic Fever (RF) and Rheumatic heart disease (RHD) are common cardiovascular diseases in developing countries. Long-term Benzathine Penicillin G (BPG) injection is being used for secondary prophylaxis of RF/RHD. Although allergic reactions to BPG are rare, there is a lot of fear and hesitancy in administering it. Objective: The objective of this study is to assess the safety of injection BPG used for secondary prophylaxis of RHD. Methods: Patients who had received secondary prophylaxis to RHD at our institute's outpatient department from January 1, 2015 to December 31, 2020, were analysed retrospectively. Results: Among 25,819 injections of BPG given to 2878 patients, eight patients had adverse events. Five patients had anaphylaxis, two had urticaria, and one had vasovagal syncope. Incidence of adverse events was 0.03% of injections and 0.28% of patients. Majority of adverse events were seen in patients more than 18 years (7 out of 8). All were treated successfully and there was no mortality. Conclusions: Life-threatening allergic reactions are very rare in patients on long-term intramuscular BPG for secondary prevention of RHD.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"129 - 132"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46839066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotype-based prediction for cardiovascular disease risk using polymorphism in rs10757278 at 9p21 locus","authors":"Geetha Bhaktha, S. Nayak","doi":"10.4103/jcpc.jcpc_3_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_3_21","url":null,"abstract":"Background and Aims: Along with the conventional risk factors and based on the Framingham risk score, a preventive measure can be targeted in those subjects who are in risk category. The use of genotype-based assessment in these subjects can be much benefited in clinical decision-making. Hence, we aimed to match the risk frequency with genotype score for rs10757278 in asymptomatic coronary heart disease (CHD) individuals. Methods: This is a cross-sectional study with 105 participants. These subjects were without any clinical presentation of CHD. Single-nucleotide polymorphism 10757278 was genotyped using tetra-primer amplification refractory mutation system–polymerase chain reaction. Results: The minor allele frequency was 0.84 higher though the subjects were asymptomatic. When the group was categorized using Framingham risk score (low, moderate, and high), it was observed that the risk allele was 0.74 versus 0.77 versus 0.93. The risk allele frequency (male) in low, moderate, and high groups was 0.76 versus 0.79 versus 0.94. This incremental rise was lost in females with risk allele frequency to be 0.81 versus 0.76 versus 0.87. It is observed that the association between gender and risk status was significant (P < 0.001) both while considering risk wise and even after considering the risk allele. Conclusion: A good individual predicted risk can be assessed using global risk stratification along with the knowledge of the interaction of genetics. Further, to determine the accuracy and clinical utility of such reclassification, more prospective studies are needed.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"133 - 138"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46826081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To study the prescription patterns and adequacy of use of statins at a tertiary care center of North India","authors":"Suraj Khanal, S. Atwal, P. Dutta","doi":"10.4103/jcpc.jcpc_22_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_22_21","url":null,"abstract":"Background: The role and benefits of lipid-lowering drugs in active management of dyslipidemia are well established. However, a little is known about whether these drugs are prescribed as per the recent guidelines and the desired effect is achieved or not in routine clinical practice. The aim of this study was to evaluate the prescription patterns and adequacy of use of statins at a tertiary care hospital. Patients and Methods: Patients aged ≥18 years eligible to receive statin therapy for primary or secondary prevention according to the American Heart Association 2018 guidelines were included in the study. Clinical records of all the cases were reviewed for indications of statins, and lipid profile was done at baseline and after 3 months of statin therapy. Results: There were 140 men and 103 women with a mean age of 52.24 ± 12.01 years. 109 (44.9%) patients received statins for primary prevention, whereas 134 (55.1%) patients received statins for secondary prevention. A total of 179 (73.7%) and 64 (26.3%) patients each received atorvastatin and rosuvastatin. 81.9% of the study population received statins according to the guidelines. After 3 months of statin therapy, there was a statistically significant change in the lipid profile in both primary and secondary prevention groups. Conclusions: There are some irrational prescribing practices among physicians affecting the performance of statin therapy in primary and secondary prevention of atherosclerotic cardiovascular disease. A need to rationalize the prescription practices by keeping abreast with the latest recommendations as well as effective patient counseling and education seems warranted.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"122 - 128"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42392594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Acute decompensated heart failure with reduced ejection fraction: Common etiological cause and predictor of mortality in the Nepalese population","authors":"","doi":"10.4103/2250-3528.333706","DOIUrl":"https://doi.org/10.4103/2250-3528.333706","url":null,"abstract":"","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"151 - 151"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44783332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Page October 2021","authors":"R. Kasliwal","doi":"10.4103/2250-3528.333699","DOIUrl":"https://doi.org/10.4103/2250-3528.333699","url":null,"abstract":"","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"121 - 121"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41682197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BailOut angioplasty in a case of thrombus migration","authors":"R. Rai, Shrishail Jalkote, S. Shaikh, A. Gupta, N. Bansal","doi":"10.4103/jcpc.jcpc_1_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_1_21","url":null,"abstract":"Acute myocardial infarction with high thrombus burden poses a challenge to the operating surgeon. Thrombus migration can worsen the clinical condition by further occluding flowing vessels. In our case of acute anterior wall myocardial infarction, thrombus migration from left anterior descending (LAD) caused obstruction of the left circumflex artery (LCX), and ramus. Bailout percutaneous transluminal coronary angioplasty (PTCA) was done to LCX, ramus, and left main which helped the patient hemodynamically but soon succumbed to sudden cardiorespiratory arrest. Hence, bailout PTCA remains a challenging procedure.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"144 - 146"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44161641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary collateral circulation in acute, subacute, and chronic total occlusions","authors":"A. Sarojadevi, V. Venugopal","doi":"10.4103/jcpc.jcpc_5_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_5_21","url":null,"abstract":"Context: A study on the pattern of coronary collateral circulation is relevant in coronary artery disease (CAD) where despite advances in revascularization, the prevalence of heart failure is increasing. Aims: The aim was to study the pattern of coronary collateral circulation in acute, subacute, and chronic coronary total occlusions and to find out the association between collateral grade with the severity of CAD. Settings and Design: This was a hospital-based retrospective cross-sectional study of 141 patients with acute, subacute, or chronic total occlusion of coronaries detected by coronary angiography. Subjects and Methods: Data of 141 patients with total occlusion of coronaries detected by coronary angiography were analyzed. Collateral grading was done according to the Rentrop classification and Werner classification. The severity of CAD was assessed using Gensini score and Syntax score. Pattern of collateral circulation in different types of coronary occlusions and the association between collateral grade and severity of CAD were assessed. Statistical Analysis Used: The association of categorical clinical and angiographic features with type of occlusion was tested using Chi-square test and that of continuous variable with student t-test. All tests were two tailed and P < 0.05 was considered statistically significant. Results: Young patients presented predominantly with acute coronary occlusions (82.6%). About 73% of the patients with left ventricle (LV) dysfunction had acute coronary occlusions. Nearly 68.8% of patients with poor Rentrop collateral grades had LV dysfunction. Patients with acute occlusion had low atherosclerotic burden as evidenced by lower Gensini and Syntax scores and had poor coronary collaterals. No significant correlation was seen between Gensini and Syntax scores and collateral grade. Patients who presented with ST-elevation myocardial infarction (STEMI) had poor Rentrop collaterals and higher prevalence of single-vessel disease and double-vessel diseases when compared to those with non-ST-segment elevation acute coronary syndrome and chronic stable angina. Conclusions: Young male patients with low atherosclerotic burden tend to present with acute coronary occlusions. This subgroup has poor collateral circulation and LV dysfunction. No statistically significant difference was seen in the presence of diabetes, hypertension, number of epicardial coronary artery involvement, or the severity of CAD in the STEMI patients with good or poor Rentrop collaterals.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"95 - 101"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49418416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of anemia and iron deficiency among patients with heart failure admitted in a tertiary care hospital of sub-Himalayan region in North India","authors":"Akhil Katna, Himanshu Dhiman, R. Sharma, S. Raina, Mukul Kumar, R. Yadav","doi":"10.4103/jcpc.jcpc_16_21","DOIUrl":"https://doi.org/10.4103/jcpc.jcpc_16_21","url":null,"abstract":"Objective: Anemia and iron deficiency (ID) are common in patients with chronic systolic heart failure (HF). The study was planned to find out the prevalence of anemia and ID in patients of chronic HF among patients admitted in a tertiary care hospital from Himachal Pradesh, India. Methods: This was a hospital-based open cohort observational descriptive study conducted on patients diagnosed with chronic HF. The study period was of 1 year. HF was defined on the basis of 2016 ESC Guidelines for diagnosis and treatment of acute and chronic HF. Anemia was diagnosed on the basis of WHO definitions (<13 g/dl in males and <12 g/dl in females). ID was diagnosed as serum ferritin <100 μg/dl (absolute ID) or serum ferritin 100–299 μ/dl and transferring saturation <20% (functional ID). Results: A total 61 patients (41 females and 20 males) were included in the study over 1 year. Out of 61 patients, 48 (78.7%) were found to be iron deficient. Thirty-four patients were having absolute ID, whereas 14 were having functional ID. Anemia was found in 29 patients (47.5%). Nineteen patients were having ID without anemia. Conclusion: Anemia and ID are common in patients with HF in the sub-Himalayan region in North India. Hemogram and iron profile should be included in the investigation protocol during management of HF in Indian patients.","PeriodicalId":31371,"journal":{"name":"Journal of Clinical and Preventive Cardiology","volume":"10 1","pages":"102 - 105"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46222420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}