Journal of Indian Academy of Oral Medicine and Radiology最新文献

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Hepcidin as a risk marker for cardiovascular disease in periodontitis—A case control study 作为牙周炎心血管疾病风险标志物的肝素--病例对照研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_156_23
Pooja Sinha, T. Nagaraj, VS Vaishnavi, HolenarasipurNagesh Santosh, Durga Okade, J. Anitha
{"title":"Hepcidin as a risk marker for cardiovascular disease in periodontitis—A case control study","authors":"Pooja Sinha, T. Nagaraj, VS Vaishnavi, HolenarasipurNagesh Santosh, Durga Okade, J. Anitha","doi":"10.4103/jiaomr.jiaomr_156_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_156_23","url":null,"abstract":"Background: Hepcidin is a 25 amino acid peptide expressed in the liver. Discovered as late as 2002, hepcidin is a master regulator of iron metabolism and is sensitive to inflammation. Chronic periodontitis, being an inflammatory condition, affects levels of hepcidin. There exists a linear correlation between chronic generalized periodontitis (CGP) and cardiovascular disease (CVD). Objective: To assess and compare serum hepcidin between Group I (Control Group—CGP without CVD) and Group II (Case Group—CGP with CVD). Methods: Blood samples of 20 patients from Group I and 20 patients from Group II were collected and centrifuged to separate serum samples. ELISA kit was used for the estimation of serum hepcidin levels. The statistical analysis was done using G-Power version 3.1 software. Results: The serum hepcidin levels in Group I and Group II were found to be insignificant (P = 0.742679, P < .05). Conclusion: Serum hepcidin levels were higher in Group I when compared with Group II. We can conclude that there is an increase in the hepcidin levels due to inflammatory conditions. However, using hepcidin as a biomarker in CVD needs further examination using a larger sample size with long-term observations.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"38 1","pages":"315 - 318"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Oral Mucosal Changes by Ultrasonography and Color Doppler in Oral Submucous Fibrosis: A Case–Control Study 通过超声波和彩色多普勒评估口腔黏膜下纤维化的口腔黏膜变化:病例对照研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_206_23
Binindita Bhunia, Vaishali Rajashekar, David Priscilla, G. Roopashri, Vijayalakshmi Nandini, Poojya Ramdev
{"title":"Assessment of Oral Mucosal Changes by Ultrasonography and Color Doppler in Oral Submucous Fibrosis: A Case–Control Study","authors":"Binindita Bhunia, Vaishali Rajashekar, David Priscilla, G. Roopashri, Vijayalakshmi Nandini, Poojya Ramdev","doi":"10.4103/jiaomr.jiaomr_206_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_206_23","url":null,"abstract":"Background: Oral submucous fibrosis (OSMF) is an insidious chronic disease involving any part of the oral cavity. As ultrasonography (USG) facilitates imaging of a wider area, it can be a valuable tool to determine the severity of this disease. Objective: With this background, this study was undertaken to assess oral mucosal changes by ultrasonography and color Doppler in OSMF. Materials and Methods: The sample size included 40 subjects between 20 and 60 years inclusive of either gender, divided into group 1 (controls) and groups II, III, and IV (OSMF cases). The submucosal thickness of buccal mucosa and upper and lower labial mucosa was measured by USG followed by analysis of submucosal vascularity by color Doppler. The data were subjected to statistical analysis. Results: It was found that all the subjects had normal submucous thickness and normal vascularity in group 1 (controls). In group II to group III to group IV cases, there was an increase in submucosal thickness and a decrease in submucosal vascularity as the stage of OSMF progressed and the results were statistically significant. Conclusion: USG and color Doppler were able to demonstrate an increase in the thickness of the submucosal layer and a decrease in submucosal vascularity with the progression of OSMF. Hence, USG assessment of OSMF can supplement with other modalities for monitoring disease progression.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"86 1","pages":"373 - 377"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soft and hard tissue changes after photodynamic therapy in aggressive periodontitis: A systematic review and meta-analysis 侵袭性牙周炎光动力疗法后软组织和硬组织的变化:系统回顾与荟萃分析
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_81_23
Srushti Dhande, S. Rathod, P. Bawankar, A. Kolte, Palak Kasliwal
{"title":"Soft and hard tissue changes after photodynamic therapy in aggressive periodontitis: A systematic review and meta-analysis","authors":"Srushti Dhande, S. Rathod, P. Bawankar, A. Kolte, Palak Kasliwal","doi":"10.4103/jiaomr.jiaomr_81_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_81_23","url":null,"abstract":"In the nonsurgical therapy of periodontal disease, scaling and root planing (SRP) is the gold standard. Bacterial recolonization occurs from the residual subgingival plaque or from other oral contaminants. To avoid bacterial recolonization, regular periodontal care is essential, as well as the inclusion of coadjutants and active debridement, including such antibiotic therapy and photodynamic therapy. Therefore, the aim of this systematic review and meta-analysis is to evaluate periodontal tissue changes after photodynamic therapy in aggressive periodontitis. An electronic search was conducted on PubMed/ MEDLINE, GOOGLE SCHOLAR, and HAND SEARCH of a reference list of archived articles published from January 2015 to August 2018. After thorough scrutiny, five studies assessing clinical attachment level (CAL) and probing pocket depth (PPD) were considered for the meta-analysis. Using fixed and random effect models, the standardized mean differences (SMDs) were calculated. Results of the fixed and random-effect models had slightly distinct estimates of SMD of CAL, both models resulted in positive and significant treatment effects. The fixed effect was slightly different and positive for PPD (SMD = 0.843, 95 percent CI = 0.510 to 1.176, P = 0.001, significant), while random effects were somewhat different and positive for PPD (SMD = 1.227, 95 percent CI = -0.129 to 2.582, P = 0.076, not significant). Because of heterogeneity, one model indicated substantial treatment effects for PPD, whereas another model showed non-significant treatment effects. Hence, the results concluded the beneficial effects of photodynamic therapy in aggressive periodontitis.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"12 1","pages":"427 - 432"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Carotid Atheroma Plaque on Panoramic Imaging in Type II Diabetes Mellitus Patients: A Systematic Review II 型糖尿病患者全景成像中颈动脉粥样斑块的患病率:系统回顾
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_225_22
M. Pavithra, Arvind Muthukrishnan
{"title":"Prevalence of Carotid Atheroma Plaque on Panoramic Imaging in Type II Diabetes Mellitus Patients: A Systematic Review","authors":"M. Pavithra, Arvind Muthukrishnan","doi":"10.4103/jiaomr.jiaomr_225_22","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_225_22","url":null,"abstract":"Background: Hyperglycemia and other risk factors lead to the formation of plaques in the neck area of the carotid artery. Carotid atheroma plaque may predispose or increase risk of cerebrovascular accident. Panoramic radiographs can pick up mere calcified plaque and early referral to a physician would prevent long-term complications. Materials and Methods: The electronic and hand search of studies published until October 2022, yielded a total of 17 articles, out of which 4 studies met the inclusion criteria. All studies examined the prevalence of carotid atheroma in panoramic images of patients with type 2 diabetes. The risk of bias was assessed by the Newcastle-Ottawa scale. Results: This systematic review search yielded 168 publications from various databases. After reading the full text, four articles were selected and met the selection criteria. All four studies showed the level of evidence IV which was assessed using Agency for Health Research and Quality (AHRO) guidelines. Conclusion: The prevalence of carotid atherosclerotic plaques is higher in diabetic patients compared to non-diabetic patients. Literature-based evidence suggests that carotid atheroma can be detected on panoramic images and the patients can be referred to a doctor for further examination and necessary treatment.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"270 1","pages":"422 - 426"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness and practice of “Spikes” protocol among post-graduate residents in delivering bad news – A cross-sectional study 一项横断面研究:毕业后的住院医师在传达坏消息时对 "尖峰 "协议的认识和实践
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_55_23
SwethaS Sharran, R. Prabhu, P. Shenoy, L. Chatra, K. Veena, Prathima Shetty
{"title":"Awareness and practice of “Spikes” protocol among post-graduate residents in delivering bad news – A cross-sectional study","authors":"SwethaS Sharran, R. Prabhu, P. Shenoy, L. Chatra, K. Veena, Prathima Shetty","doi":"10.4103/jiaomr.jiaomr_55_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_55_23","url":null,"abstract":"Background: Communication skills significantly contribute to good clinical practice. A systematic approach to delivering bad news could avoid unfavorable workplace circumstances. SPIKES protocol has been incorporated into clinical practice in many countries to deliver bad news systematically to build a better doctor–patient relationship. Objectives: To assess post-graduate residents' awareness and practice of SPIKES protocol and to determine the need for training/education for delivering bad news. Methods: A cross-sectional study among 96 post-graduates from various medical and dental clinical departments was done using a self-directed questionnaire consisting of four sections (i.e. socio-demographic data, awareness and adherence, practice, and need for training/education). The questionnaire was circulated through online platforms, and responses were tabulated. Results: About 55% of the participants were aware of the SPIKES protocol. About 90% felt that the protocol was simple, easy, and practical. 92% felt that adequate training is required for delivering bad news. Also, 90% of the participants expressed a willingness to attend training sessions to improve their communication skills. Conclusion: Only half of the study population was aware of the SPIKES protocol; among them, a fair adherence to the protocol was noted.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"76 1 1","pages":"351 - 354"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Study of Condylar Morphology by Digital Panoramic Radiographs 通过数字全景 X 光片对髁突形态进行回顾性研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_115_23
Meenakshi Bhasin, Pooja Singh, Ramesh Gupta
{"title":"A Retrospective Study of Condylar Morphology by Digital Panoramic Radiographs","authors":"Meenakshi Bhasin, Pooja Singh, Ramesh Gupta","doi":"10.4103/jiaomr.jiaomr_115_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_115_23","url":null,"abstract":"Background: Radiographical examination of temporomandibular joint (TMJ) showing changes in the shape of the condyle. Clinicians should have anatomical knowledge to assess the morphology of the condyle. Early detection of TMJ prevents the future possibility of osseous deformities. Objectives: To assess the prevalence of morphological variations in the condyles of dentate patients on digital panoramic radiographs. Methods: A total of 2364 digital panoramic radiographs were retrospectively selected from the previous patient's record that visited the Department and were observed by two radiologists for formulation of operational definitions. The OPG was evaluated for the subcondylar cysts, osteophytes, erosions, knife edges, and flattening of condyles. Morphological trends in condyles were evaluated. The obtained data were analyzed using descriptive statistics. Results: 68.73% of cases showed positive condylar changes, among which 31.13% revealed osteophytes, 27.13% flattening of condyles, 26.46% erosions, knife edges, and subcondylar cysts were 8.30%, and 6.95%, respectively, and the relationship between the type of condyles and the age groups were found to be statistically significant (P value: 0.05). Conclusions: Osteophytes were found to be the most predominant feature than other condylar morphological changes so preventive measures to be taken to stop further progression of the disease.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"5 1","pages":"417 - 421"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of posterior superior alveolar artery using cone-Beam computed tomography in the Indian population: A retrospective study 在印度人群中使用锥形束计算机断层扫描评估肺泡后上动脉:回顾性研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_160_23
Isha Kale, AmitA Mhapuskar, Pradnya Karmarkar, Muskan Jhawar, Darshan Prasad Hiremutt, Abhijeet Jadhav
{"title":"Evaluation of posterior superior alveolar artery using cone-Beam computed tomography in the Indian population: A retrospective study","authors":"Isha Kale, AmitA Mhapuskar, Pradnya Karmarkar, Muskan Jhawar, Darshan Prasad Hiremutt, Abhijeet Jadhav","doi":"10.4103/jiaomr.jiaomr_160_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_160_23","url":null,"abstract":"Background: The posterior superior alveolar artery (PSAA) is commonly encountered during various surgical procedures such as sinus lift, osteotomy, and Le Fort I fractures. Objective: This study was undertaken to evaluate the anatomical relationship of PSAA with the alveolar crest using cone-beam computed tomography (CBCT). Methods: This retrospective, analytical, comparative study was conducted on 192 CBCT scans (=384 PSAA notches) of dentulous patients above the age of 20 years. The position, diameter, and distance of the artery to the alveolar crest in the first molar region were evaluated bilaterally, in different age groups and among both genders. Results: In our study, the position and dimension of the notch of the PSAA were statistically significant with respect to age. The distance of the artery to the alveolar crest was statistically significant with respect to age and gender. No side differences were seen. Conclusion: The distance of the PSAA to the alveolar crest in the first molar region was approximately 14.62 mm in the Indian population. Hence, surgical procedures involving this artery should be conducted at a distance of <14 mm to avoid hemorrhage. CBCT can be used to evaluate the position and path of the PSAA accurately.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"20 1","pages":"383 - 387"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of sexual dimorphism of maxillary sinus from morphometric measurements using cone beam computed tomography (CBCT)- A cross sectional study 通过锥形束计算机断层扫描(CBCT)的形态测量评估上颌窦的性双态性--一项横断面研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_342_22
S. Patil, Amita Aditya, Kedarnath Kalyanpur, Antara Kore
{"title":"Evaluation of sexual dimorphism of maxillary sinus from morphometric measurements using cone beam computed tomography (CBCT)- A cross sectional study","authors":"S. Patil, Amita Aditya, Kedarnath Kalyanpur, Antara Kore","doi":"10.4103/jiaomr.jiaomr_342_22","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_342_22","url":null,"abstract":"Background: Gender determination is a standard practice in forensic science as it forms the prime phase in the reconstruction of a post-mortem profile. The maxillary sinus (MS) is the largest among the paranasal sinuses with characteristic morphological features. Cone-beam computed tomography (CBCT) imaging, widely popular now for its imaging accuracy, may be considered for recording morphometric measurements of maxillary sinuses for gender determination. Aim: To compare and analyze the applicability and accuracy of measurement parameters (length, width, height, and volume) for the evaluation of sexual dimorphism of MS. Methods: CBCT scans were used to measure the height, length, width, and volume of MS in 60 patients to identify an individual's gender for forensic evaluation. The parameters were analyzed using discriminant function analysis and independent t test to compare these values in both genders. Results: Combined measurements of all study parameters were analyzed, and an overall accuracy rate of 61.67% was observed. Conclusion: Morphometric measurement parameters of MS attained using CBCT seem to have a moderately good prediction value.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"8 1","pages":"412 - 416"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of anastomosis canal in maxillary sinus walls using cbct in South Indian population: A cross-sectional study 在南印度人群中使用 cbct 评估上颌窦壁吻合管:横断面研究
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_5_23
A. Shiny, Jaishankar Hombarvali, Karthikeya Patil
{"title":"Evaluation of anastomosis canal in maxillary sinus walls using cbct in South Indian population: A cross-sectional study","authors":"A. Shiny, Jaishankar Hombarvali, Karthikeya Patil","doi":"10.4103/jiaomr.jiaomr_5_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_5_23","url":null,"abstract":"Background: Intraosseous anastomosis (IA) found in the lateral wall of the maxillary sinus (MS) is a potential site for bleeding during surgeries. Objectives: To investigate the position of IA in male and female, and dentulous and edentulous patients in relation to the MS floor and volume of MS. Methods: The study is comprised of 60 cone-beam computed tomography (CBCT) scans of the maxilla. Distances from the floor of the MS to the IA canal and from the MS floor to the alveolar crest were measured. The canals are classified into three types. The volume of the MS and its relation to the IA was assessed. Results: Statistical difference was noted in the position of the IA in relation to second premolar and in dentulous and edentulous patients. Intraosseous was the most common type of canal. The difference in volume did not affect the position of the canal. Conclusions: IA was closer to the floor of the MS in the second premolar region in females. Knowing the type and position of the canal helps prevent complications during surgery.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"58 1","pages":"393 - 397"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of micronuclei in potentially malignant disorders and oral cancers: A cytological assay 评估潜在恶性疾病和口腔癌中的微核:细胞学检测
IF 0.3
Journal of Indian Academy of Oral Medicine and Radiology Pub Date : 2023-07-01 DOI: 10.4103/jiaomr.jiaomr_40_23
Aishwarya Bhatnagar, Madhav Nagpal, Jyothi Kumar, Anamika Joshi, Sudhir Baroopal, Kailash Kewalia
{"title":"Evaluation of micronuclei in potentially malignant disorders and oral cancers: A cytological assay","authors":"Aishwarya Bhatnagar, Madhav Nagpal, Jyothi Kumar, Anamika Joshi, Sudhir Baroopal, Kailash Kewalia","doi":"10.4103/jiaomr.jiaomr_40_23","DOIUrl":"https://doi.org/10.4103/jiaomr.jiaomr_40_23","url":null,"abstract":"Objective: The present study aims to evaluate the number of micronuclei (MN) in potentially malignant disorders (PMDs) and oral cancer and correlates them with the control group. Materials and Methods: Subjects included in the study were equally divided into four groups. Exfoliated cells were then obtained from the buccal mucosa using cytological brush. Smears were stained using rapid Pap stain. The smears were observed using a light microscope, and MN was counted out of 10 high-power fields and scored according to PE Tolbert (1992) criteria. Results: The mean MN count was found to be 0.23, 2.10, 3.03, and 3.57 in groups I, II, III, and IV, respectively. The overall intergroup comparison between the four groups was found to be statistically significant with a P value less than 0.05. Conclusion: This study gives a fair assessment that MN assay in exfoliated cells of oral epithelium can be a conducive biomarker while screening for PMDs of the oral cavity in doubtful lesions that are primarily misdiagnosed clinically.","PeriodicalId":31366,"journal":{"name":"Journal of Indian Academy of Oral Medicine and Radiology","volume":"6 1","pages":"368 - 372"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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