Nascer e Crescer最新文献_第9页

Serum sickness-like reaction in pediatric age - experience of an Imunoalergology Unit 儿童年龄的血清病样反应-免疫过敏科的经验

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.16677

Francisca Martins, T. Pereira, D. Soares, Jorge Romariz, F. Praça, Herculano Costa, C. Pedrosa

{"title":"Serum sickness-like reaction in pediatric age - experience of an Imunoalergology Unit","authors":"Francisca Martins, T. Pereira, D. Soares, Jorge Romariz, F. Praça, Herculano Costa, C. Pedrosa","doi":"10.25753/BIRTHGROWTHMJ.V28.I3.16677","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V28.I3.16677","url":null,"abstract":"Background: Serum sickness is a systemic reaction reported after administration of heterologous serum. It is clinically characterized by fever, skin lesions, arthralgia/arthritis, lymphadenopathy, and nephritis and by presence of immune complexes. Serum sickness-like reaction mimics serum sickness and its pathophysiology is not well understood. It is more common in pediatric age and often associated with drug administration. This study aimed to characterize serum sickness-like reaction cases evaluated at a Drug Allergy Clinic. Material and methods: An analytical, retrospective, longitudinal study of a sample of 39 children (56% male) with diagnosis of serum sickness-like reaction evaluated at a Drug Allergy Clinic between January 2007 and December 2017 was performed. Results: Children had an average of 4.8 years at the time of reaction. In most cases (97%), beta-lactam antibiotics were the suspected triggering drugs. On average, clinical manifestations developed 7.5 days after treatment start. Skin lesions developed in all patients, and arthralgia/arthritis in 92.3%. Fifteen percent of children were hospitalized. Penicillin-specific IgE was evaluated in 87% of patients, but only tested positive in two. Skin prick tests and intradermal tests were performed in 46% of cases and were positive in seven. Oral challenge test was performed in 26% of patients and was positive in three. Conclusion: Serum sickness-like reaction is a rare and poorly understood entity. Diagnosis is essentially clinical, requiring a high index of suspicion. In the acute phase, usefulness of complementary tests lies mainly in the differential diagnosis with other diseases.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"36 1","pages":"120-125"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81918454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retroperitoneal paraganglioma, a rare cause of arterial hypertension 腹膜后副神经节瘤，一种罕见的动脉高压病因

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.14159

M. Branco, Francisca Martins, Ariana Teles, V. Gonçalves, F. Ribeiro‐Mourão, I. Maciel, A. Carneiro

{"title":"Retroperitoneal paraganglioma, a rare cause of arterial hypertension","authors":"M. Branco, Francisca Martins, Ariana Teles, V. Gonçalves, F. Ribeiro‐Mourão, I. Maciel, A. Carneiro","doi":"10.25753/BIRTHGROWTHMJ.V28.I3.14159","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V28.I3.14159","url":null,"abstract":"Introduction: Paragangliomas are rare tumors in pediatric age, derived from sympathetic tissue of extra-adrenal location or parasympathetic tissue. Some of these tumors secrete catecholamines, being a rare cause of hypertension. Clinical Case: A female adolescent, with 14 years old and unremarkable medical history, was referred to the Pediatric consultation due to episodes of holocranial headache associated with blurred vision with six months of evolution. Physical examination and brain magnetic resonance imaging revealed no abnormalities. Physical examination showed stage 1 hypertension, later confirmed by ambulatory blood pressure measurement. Analytical study, chest X-ray, electrocardiogram, and echocardiogram were normal. Renal echography revealed a heterogeneous mass contiguous to the left renal sinus and abdominal computed tomography showed a retroperitoneal lesion in the medial side of the left perirenal space. Due to retroperitoneal paraganglioma suspicion, the patient was referred to Porto’s Portuguese Institute of Oncology, where surgical excision of the lesion was performed. Anatomopathological examination confirmed diagnosis of sympathetic paraganglioma. Conclusion: Although rare in pediatric age, paragangliomas represent the most common endocrine tumor. Biochemical and imaging evaluation are key for diagnosis, after which a genetic study is recommended due to its relevance for patient management and follow-up. Treatment consists in surgical excision, and complete remission is achieved in approximately 90% of cases.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"28 1","pages":"150-153"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47519873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Desafios na abordagem da anorexia nervosa em pacientes com perturbação do espetro do autismo 解决自闭症谱系障碍患者神经性厌食症的挑战

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.15066

S. Cunha, Isabel Taveira Gomes, J. Guerra

引用次数: 0

Health - a human right 健康——一项人权

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.18702

P. Ferreira

引用次数: 0

Association between food allergy and otitis media with effusion in light of current knowledge 根据现有知识，食物过敏与渗出性中耳炎的关系

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.15671

G. Mendes, L. Brosseron, I. Lopes, A. Magalhães, C. Sousa

引用次数: 0

Treatment of acute migraine and status migrainosus in pediatrics 儿童急性偏头痛和偏头痛状态的治疗

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.15431

Raquel M A Alves, M. Lopes, R. Rocha, I. Carrilho

{"title":"Treatment of acute migraine and status migrainosus in pediatrics","authors":"Raquel M A Alves, M. Lopes, R. Rocha, I. Carrilho","doi":"10.25753/BIRTHGROWTHMJ.V28.I3.15431","DOIUrl":"https://doi.org/10.25753/BIRTHGROWTHMJ.V28.I3.15431","url":null,"abstract":"Migraine is the most common acute and recurrent headache syndrome in children and adolescents but is often underdiagnosed. Migraine diagnosis in childhood rests on criteria similar to those used in adults but with some particularities, as duration of the attack, which is often much shorter than in adults, and location of the attack, which in many children may be bilateral. Despite its high prevalence, pediatric migraine remains undertreated, sometimes due to fear of caregivers and physicians and lack of studies about its treatment. Although treatment options for pediatric migraine are increasing, they remain limited. In this article, the authors review approved and “off-label” drugs currently used in migraine and status migrainosus acute treatment in pediatric patients. In migraine treatment, nonsteroidal anti-inflammatory drugs (NSAIDs) should be used. In moderate-to-severe migraine unresponsive to analgesics or NSAIDs, triptans may be used, alone or in combination with the former. Rescue medication, including dihydroergotamine and sodium valproate, can be used in hospital setting for intractable migraine. Antiemetics with anti-dopaminergic properties may be helpful in patients with symptoms of nausea and vomiting in addition to headache, particularly when used in combination therapy.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"28 1","pages":"132-140"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44191784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent clavicle swelling in the infant 婴儿锁骨持续肿胀

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.14575

Juliana Maciel, M. Frias, Mariana Capela, M. J. Santos

引用次数: 0

Hipocalémia grave numa criança com gastroenterite ligeira 一例轻度胃肠炎患儿的严重低钾血症

Nascer e Crescer Pub Date : 2019-10-14 DOI: 10.25753/BIRTHGROWTHMJ.V28.I3.15338

Catarina Faria, C. Ferreira, Alzira Sarmento, Sara Gonçalves, P. Rocha, Carlos Duarte, C. Mota

引用次数: 0

Teste pré-natal não invasivo de aneuploidias cromossómicas fetais: o que deve ser mudado? 胎儿染色体非整倍体的无创产前检测：应该改变什么？

Nascer e Crescer Pub Date : 2019-08-09 DOI: 10.25753/BIRTHGROWTHMJ.V28.I2.18428

Luís Guedes-Martins

引用次数: 0

Stomatological clinical case 口腔临床病例

Nascer e Crescer Pub Date : 2019-07-18 DOI: 10.25753/BIRTHGROWTHMJ.V28.I2.15862

S. Pires, Flávia Belinha

引用次数: 0