Nesyia Tara Restikasari, U. Gamayani, L. Amalia, S. Dian, A. Cahyani
{"title":"Characteristics and Risk Factors of Patients with Acute Ischemic Stroke in Dr. Hasan Sadikin General Hospital Bandung, Indonesia","authors":"Nesyia Tara Restikasari, U. Gamayani, L. Amalia, S. Dian, A. Cahyani","doi":"10.15850/amj.v9n4.2362","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2362","url":null,"abstract":"Background: Stroke is the second most common cause of death globally and the third most common cause of disability. The prevalence of stroke is increasing despite managing various stroke risk factors that have improved considerably. Ischemic stroke is the most prevalent type, and about 90% of stroke events are attributable to modifiable risk factors. This study aimed to explore the characteristics and risk factors of patients with acute ischemic stroke in Dr. Hasan Sadikin General Hospital.Methods: A descriptive cross-sectional study was conducted retrospectively in October 2020, using a total sampling method on medical records of acute ischemic stroke patients in Dr. Hasan Sadikin General Hospital year 2019. Medical records with incomplete and missing data were excluded. Demographic and known risk factors data were collected and presented in the table.Results: Of the 355 subjects, male patients (n=69, 76.7%) were predominant, with the age range of 55–64 years old (36.1%). The majority of the subjects had an ischemic stroke of large-artery atherosclerosis (68.2%) with carotid system involvement (93.2%). As much as 305 subjects (85.9%) had hypertension as the risk factor, followed by dyslipidemia (47.3%), heart disease (39.4%), previous stroke history (33.8%), smoking (25.6%), diabetes mellitus (24.5%), hyperuricemia (12.1%), and blood disorders (2.3%).Conclusions: Males in the older age group have a higher risk of getting acute ischemic stroke with ischemic stroke of large-artery atherosclerosis and carotid system involvement, and hypertension has the highest prevalence.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47765039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Larvicidal Effects of Citrus Peels Extracts against Culex Pipiens Mosquitoes","authors":"A. Obembe, O. Oso","doi":"10.15850/amj.v9n4.2786","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2786","url":null,"abstract":"Background: Mosquitoes transmit severe diseases such as malaria, lymphatic filariasis, dengue fever, and yellow fever. These diseases result in significant morbidity and mortality in humans around the world. This study aimed to provide information on the larvicidal potential of different Citrus species peels against Culex mosquito larvae.Methods: Ethanol extracts of the peels of four Citrus species, such as Citrus sinensis (sweet orange), Citrus reticulata (tangerine), Citrus latifolia (lime), and Citrus paradisi (grape) fruits were tested for larvicidal properties against Culex pipiens at different concentration (3 mg, 5 mg, 7 mg and 8 mg in 100 mL) on 25 larva per concentration. Percentage mortality was recorded for each of the concentrations used. Results: Only Culex latifolia induced the death of all the mosquito larvae (100%) at 5 mg/mL concentration of the extract, meanwhile Culex reticulata resulted in the lowest mortality rate (80%). However, a hundred percent (100%) mortality of the larvae, was observed at 8 mg/mL of all the types of extracts evaluated.Conclusion: The result indicates that the peels of these Citrus species, especially Culex latifolia, hold potential for control of Culex pipiens mosquito larvae.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43719067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Chaidir, Neng Rina Susilawati, Mandala Ajie, J. Annisa, M. Jihadah
{"title":"Application of Replicate Organism Detection and Counting Method (RODAC) in Measuring Mycobacterium Tuberculosis Contamination in High Burden Laboratories","authors":"L. Chaidir, Neng Rina Susilawati, Mandala Ajie, J. Annisa, M. Jihadah","doi":"10.15850/amj.v9n4.2789","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2789","url":null,"abstract":"Background: Technicians working in high burden tuberculosis (TB) laboratories pose a higher risk of being infected by Mycobacterium tuberculosis from clinical samples. Contamination control is mandatory to detect the release of bacteria into the working environment and to minimize the risk of exposure to the workers. The contamination measurement is rarely performed due to the lack of standard methodology. This study optimized and applied a unique culture-based method named Replicate Organism Detection and Counting (RODAC) plates to assess the presence of M. tuberculosis contaminant in the laboratory with high burden of clinical samples. Methods: RODAC was applied on twenty working surfaces in the Mycobacteriology Laboratory of Universitas Padjadjaran. The results of RODAC were compared with DNA-based detection from the same working surfaces using in-house IS6110 real-time PCR (IS6110-qPCR). The detection limit of the RODAC plate was 19.6 CFU mL-1.Results: From all working surfaces tested, two distinct colonies were found on RODAC plate stamped on the Ziehl-Neelsen staining basin. Those colonies were identified as M. tuberculosis and non-tuberculous mycobacteria (NTM), as confirmed by the MPT64 antigen test and the presence of acid-fast bacilli. IS6110-qPCR detected the presence of M. tuberculosis DNA in ten sampling points, including the ZN staining basin, incubators, and microscopy areas. IS6110-qPCR detected more working surface contamination versus RODAC. However, it was noted that RODAC, which was a culture-based method, detected live bacteria, while PCR could not distinguish between live and dead bacteria.Conclusion: The application of the RODAC plate is more suitable for monitoring the contamination of live bacteria in the working environment and to inform a proper corrective action.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46521454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dinda Nursyafira Misyatin, A. Soeroto, Ferdy Ferdian
{"title":"Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019","authors":"Dinda Nursyafira Misyatin, A. Soeroto, Ferdy Ferdian","doi":"10.15850/amj.v9n4.2593","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2593","url":null,"abstract":"Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) patients based on presumptive DR-TB criteria at Dr. Hasan Sadikin General Hospital Bandung. Moreover, this study also explored the Xpert MTB/RIF Ct values.Methods: This was a descriptive-retrospective study from 570 medical records of DR-TB patients collected at the Multidrug-resistant tuberculosis (MDR-TB) clinic of Dr. Hasan Sadikin General Hospital from 2016 to 2019. The inclusion criteria were suspected patients with the Xpert MTB/RIF Ct values in the very low-low and medium-high categories. Data were analyzed using frequency distribution. Results: The most common presumptive DR-TB criteria among DR-TB patients were relapse cases (52.3%). Presumptive DR-TB criteria, with a high percentage result of medium-high Ct values, were category II treatment failure (80.9%).Conclusion: Relapse case and category II treatment failure are presumptive DR-TB criteria, which need more attention from clinicians.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44940465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aziza Salsabila, Lina Lasminingrum, Sally Mahdiani, S. F. Boesoirie, B. Purwanto
{"title":"Level of Knowledge, Attitude, and Practices of General Physicians in West Java, Indonesia on Middle Ear Inflammation","authors":"Aziza Salsabila, Lina Lasminingrum, Sally Mahdiani, S. F. Boesoirie, B. Purwanto","doi":"10.15850/amj.v9n4.2655","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2655","url":null,"abstract":"Background: The prevalence of middle ear inflammation in West Java is still relatively high. General practitioners are at the forefront who see and treat the patients directly; thus, the number of cases can be reduced by increasing the competence of general practitioners. This study aimed to determine the level of knowledge, attitude, and practices of general practitioners in West Java towards middle ear inflammation, as an evaluation for improving health services in the community.Methods: This research was a descriptive study with a questionnaire conducted in August–December 2021 conducted online with a probability sampling technique of at least 368 general practitioners in West Java. The level of knowledge, attitude, and practices were calculated using the Guttman scale. The data were presented as a frequency distribution.Results: The results showed that the majority of the general practitioners still had poor knowledge of middle ear inflammation (n=325; 84.6%) as well as the attitude (n=333; 86.7%) and the level of practice (n=340; 88.5%).Conclusions: The level of knowledge, attitude, and practices of general practitioners in West Java towards middle ear inflammation is poor. Special interventions and approaches are needed to improve the competence of general practitioners in West Java based on the Standard Competency of Indonesian Doctors.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45163937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factor of Stillbirth among Pregnant Women at Dr. Hasan Sadikin General Hospital Bandung from 2017–2020","authors":"D. Immanuel, H. Susiarno, W. Nurdiawan","doi":"10.15850/amj.v9n4.2646","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2646","url":null,"abstract":"Background: Stillbirth is one of the most devastating pregnancy outcomes that affects approximately 2.6 million pregnancies worldwide. Several factors have been identified to be associated with stillbirth, and grouped based on the pathophysiological aspects, such as maternal, placental, fetal, and unknown or unexplained factors. This study aimed to describe the prevalence, along with the baseline and risk factor characteristics of stillbirth among singleton pregnancies at Dr. Hasan Sadikin General Hospital Bandung. Methods: A descriptive, cross-sectional study design was conducted, including all stillbirth medical records from 2017 to 2020 obtained from the Department of Obstetrics and Gynecology, Dr. Hasan Sadikin General Hospital Bandung. Medical records with complete baseline data, 2nd–3rd trimester pregnancies, and singleton pregnancies were collected.Results: The prevalence of stillbirth cases in this study was 2.2%. Most of the cases occurred in the age range of 20–35 years old (64.4%) with the gestational age of >28 weeks (65.8%). Of all risk factors observed, hypertensive disorders were the most common medical conditions found (45.6%), followed by unknown factors (17.8%), and congenital abnormalities (14.2%).Conclusions: The majority of stillbirth patients are at their optimal reproductive age, nulliparity, and have hypertensive disorders during pregnancy, specifically the superimposed preeclampsia subtype. Although the prevalence is considerably low, early management of the risk factors, particularly hypertensive disorder, is important to prevent its occurrence.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43790223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nubella Citresna Zakiyyah, Suryani Gunadharma, A. Ganiem
{"title":"Outcomes of Tuberculous Meningitis Patients with or without Hydrocephalus from a Tertiary Hospital in West Java, Indonesia","authors":"Nubella Citresna Zakiyyah, Suryani Gunadharma, A. Ganiem","doi":"10.15850/amj.v9n4.2304","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2304","url":null,"abstract":"Background: Tuberculous meningitis (TBM) is a severe form of extrapulmonary tuberculosis. One of the most common complications of TBM is hydrocephalus, with a higher risk of mortality. This study aimed to evaluate the outcome among TBM patients with or without hydrocephalus.Methods: This study was a retrospective cross-sectional comparative analytical study. A total sampling was employed based on the number of traceable resumes of TBM patients treated at the Department of Neurology Dr. Hasan Sadikin General Hospital, Bandung, Indonesia in 2018. Results: Of the 127 data of TBM patients, 55 (43.3%) had hydrocephalus, and 72 (56.7%) did not. The median age of TBM patients with and without hydrocephalus was 34 years (IQR 26–45) and 35 years (IQR 24–44), respectively. Decreased consciousness dominated the clinical symptoms for 94.5% in the hydrocephalus group and 84.7% in the non-hydrocephalus group. Hospital-acquired pneumonia occurred mainly in the hydrocephalus group (29.1%), whereas urinary tract infections mainly occurred in without hydrocephalus group (18%). There was a significant difference between the outcome of hydrocephalus and non-hydrocephalus (p=0.005). Mortality was higher in patients with hydrocephalus compared to those without hydrocephalus.Conclusions: The outcome of TBM patients with hydrocephalus is worse than those without hydrocephalus, as reflected by a higher grade of TBM, higher mortality rate, and lower good recovery upon treatment administration. Therefore, prompt diagnosis and treatment are needed to improve the outcome and survival among TBM patients with hydrocephalus.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41986744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physical Fitness Is Correlated with Quality of Life among Elderly Gymnastics Club from Haji General Hospital Surabaya, Indonesia","authors":"H. Hasan, Rita Vivera Pane","doi":"10.15850/amj.v9n4.2791","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2791","url":null,"abstract":"Background: Indonesia is the fourth most populated country, of whom 10.8% are elderly people. The quality of life (QOL), which includes physical health, psychological health, social relationships, and the environment, is crucial as physical fitness may reflect the ability to perform daily activities without significant fatigue. The objective of this study was to explore the correlation of physical fitness with the QOL among the elderly.Methods: This was an analytic observational study with a cross-sectional approach, including members of the elderly gymnastics club of the Haji General Hospital Surabaya. The physical fitness value was measured based on VO2max using a 6-minute walk test (6MWT). The VO2max (0.03 x mileage(m) + 3.98 cc/kilogram body weight/minute) was categorized into poor, moderate, and good. The QOL was assessed with WHOQOL-100 and grouped into poor, moderate, and good QOL. Data were analyzed by the Spearman correlation test.Results: In total, 33 elderly were recruited, with an average age was 67.85±6.11 years (range 60–78), mean height was 1.49±0.09 m, mean weight was 57.65±10.53 kg, and mean BMI was 24.92±3.69. The mean VO2max was 16.96±2.37, and the QOL was 64.61±6.82 mL/kg/minute. The 6MWT resulted in the physical fitness of poor (15%; n=5), moderate (36%; n12), and good (48%; n16). The WHOQOL assessment showed moderate (30%; n=10) and good (61%; n=23) QOL. Spearman correlation test results showed a correlation between physical fitness and the QOL (coefficient 0.356 and p= 0.042).Conclusions: There is a correlation between physical fitness and QOL among the elderly, suggesting that increasing physical fitness among the elderly, adjusted to their physical health condition, is important to get a good quality of life.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44735825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Triatin, Lulu Eva Rakhmilia, Y. Sribudiani, Susi Susanah
{"title":"Knowledge towards Thalassemia and Willingness to Screen among Students in Public Senior High School 3 Bandung","authors":"R. Triatin, Lulu Eva Rakhmilia, Y. Sribudiani, Susi Susanah","doi":"10.15850/amj.v9n4.2730","DOIUrl":"https://doi.org/10.15850/amj.v9n4.2730","url":null,"abstract":"Background: Thalassemia carrier screening is a major preventive measure potentially influenced by the level of knowledge, particularly in adolescents. Therefore, this study aimed to analyze the effect of health education on knowledge of thalassemia in adolescents and its association with their willingness to do thalassemia screening.Methods: A cross-sectional study was conducted using data regarding knowledge of thalassemia before and after health education sessions from 229 students at Public Senior High-School 3 Bandung. All participants attended a one-day health education in July 2019. A questionnaire was filled in to measure their knowledge regarding thalassemia before and after the session, including knowledge on etiology and definition, risk of disease, clinical manifestations, treatment, complication, prognosis, and disease prevention. Only data with complete questionnaire responses were included. These responses were scored quantitatively and analyzed for their association with participants’ willingness to screen. Results: Participants were knowledgeable concerning thalassemia before the health education session (median, range: 60.0, 25.0-90.0), and knowledge was increased significantly after the education session (median, range: 80.0, 35.0-100.0) with an increased median difference=19.99 (p-value <0.001). Although there was no significant association between the overall post-test score on participants’ willingness to screen (p-value >0.05), the willingness was slightly associated with improved knowledge regarding the risk of disease (OR: 1.02; 95%CI: 1.00-1.03; p-value <0.005). Conclusion: Health education regarding thalassemia significantly increases general knowledge of thalassemia. However, improving knowledge is not significant in influencing adolescents’ motivation to take the screening tests.","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42341368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Signs in Allergic Rhinitis Patients at Dr. Hasan Sadikin General Hospital Bandung 2017-2021","authors":"Exel Billy Wibowo, Arif Dermawan, Melati Sudiro","doi":"10.15850/amj.v9n3.2682","DOIUrl":"https://doi.org/10.15850/amj.v9n3.2682","url":null,"abstract":"Background: The clinical diagnosis of allergic rhinitis requires comprehensive data from the history and physical examination. Despite being a substantial component of the diagnosis for allergic rhinitis, there is a paucity of studies about clinical signs of allergic rhinitis in Indonesia. This study aimed to describe the clinical signs in allergic rhinitis patients at Dr. Hasan Sadikin General Hospital Bandung.Methods: This cross-sectional study was conducted at Dr. Hasan Sadikin General Hospital Bandung in 2021, including secondary data of patients with allergic rhinitis from medical records registered from 2017 to 2021. Data of the characteristics, clinical signs, and allergic rhinitis comorbidities were collected and presented in tables.Results: The most common clinical sign was turbinate hypertrophy (74%), followed by pale nasal mucosa (59%) and clear nasal discharge (59%). The most prevalent comorbidities were chronic rhinosinusitis, adenoid hypertrophy, and asthma.Conclusions: The clinical signs observed from allergic rhinitis patients may vary, with the most common findings, including nasal turbinate hypertrophy, pale nasal mucosa, and clear nasal discharge. The findings may help the clinicians to diagnose allergic rhinitis needed for therapy management. ","PeriodicalId":31310,"journal":{"name":"Althea Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42372162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}