2016-2019年Dr. Hasan Sadikin医院基于推定耐药结核病标准的利福平耐药结核病患者分布

Dinda Nursyafira Misyatin, A. Soeroto, Ferdy Ferdian
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引用次数: 0

摘要

背景:耐药结核病(DR-TB)的诊断始于使用Xpert MTB/RIF识别推定的DR-TB患者,作为检测对利福平耐药性的诊断测试。该研究旨在根据Hasan Sadikin医生万隆综合医院的DR-TB标准,确定耐利福平结核病(RR-TB)患者的分布。此外,本研究还探讨了Xpert MTB/RIF Ct值。方法:这是一项描述性回顾性研究,来自Hasan Sadikin综合医院耐多药结核病(MDR-TB)诊所2016年至2019年收集的570份DR-TB患者病历。纳入标准为Xpert MTB/RIF Ct值在极低-低和中-高类别中的疑似患者。使用频率分布对数据进行分析。结果:DR-TB患者中最常见的DR-TB推定标准是复发病例(52.3%)。推定DR-TB标准为II类治疗失败(80.9%),Ct值中高的比例较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Distribution of Rifampicin-Resistant Tuberculosis Patients based on Presumptive Drug-Resistant Tuberculosis Criteria at Dr. Hasan Sadikin Hospital 2016–2019
Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) patients based on presumptive DR-TB criteria at Dr. Hasan Sadikin General Hospital Bandung. Moreover, this study also explored the Xpert MTB/RIF Ct values.Methods: This was a descriptive-retrospective study from 570 medical records of DR-TB patients collected at the Multidrug-resistant tuberculosis (MDR-TB) clinic of Dr. Hasan Sadikin General Hospital from 2016 to 2019. The inclusion criteria were suspected patients with the Xpert MTB/RIF Ct values in the very low-low and medium-high categories. Data were analyzed using frequency distribution. Results: The most common presumptive DR-TB criteria among DR-TB patients were relapse cases (52.3%). Presumptive DR-TB criteria, with a high percentage result of medium-high Ct values, were category II treatment failure (80.9%).Conclusion: Relapse case and category II treatment failure are presumptive DR-TB criteria, which need more attention from clinicians.
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