{"title":"A Case Report on Pituitary Apoplexy","authors":"R. Jha, Rupak Raj Ghimire","doi":"10.3126/jbsfn.v2i2.45121","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i2.45121","url":null,"abstract":"Objective: To report a case of pituitary apoplexy presenting with unilateral ptosis and unilateral third nerve palsy in diabetic and hypertensive patient.\u0000Clinical Presentation and Intervention: A 50 years old man developed unilateral third nerve palsy. A pituitary macro adenoma with hemorrhagic and necrotic changes on MRI scan was resected by endoscopic transsphenoidal procedure. Third nerve palsy improved promptly and completely few hours postoperatively.\u0000Conclusion: This is a rare case of pituitary apoplexy that presented with unilateral third cranial nerve palsy recovered promptly after surgical excision of mass.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126337115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shiwani Rai, N. Yogi, B. Karmacharya, M. Maharjan, K. Koirala
{"title":"Otorhinolaryngological manifestations in Traumatic brain injury in a tertiary care center of western Nepal","authors":"Shiwani Rai, N. Yogi, B. Karmacharya, M. Maharjan, K. Koirala","doi":"10.3126/jbsfn.v2i2.45116","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i2.45116","url":null,"abstract":"Introduction: Otorhinolaryngological injuries in head injury are something which are very common but yet are overlooked, missed and at times forgotten. In this study, we tried to see the epidemiological characteristics, clinical presentations and management of these associated injuries in cases of head injuries in a tertiary care center in western Nepal.\u0000Methods: An analytical study was done in all cases of head injury admitted to neurosurgical ward and ICU in between January 2019 to December 2019. Various clinical and epidemiological details were collected from the patient’s records obtained from Medical Records Department and charted in a preformed performa. All the continuous data were presented in terms of mean and standard deviation and categorical data in terms of percentage. Statistical analysis was done using SPSS 22.0 software.\u0000Results: Soft Tissue lacerations were the commonest findings in all head injuries; nose and face lacerations (29.5%), ear lacerations (23.5%) followed by facial bone fractures (19.2%). There were 41(52.6%) cases with mild head injury, 23 (29.5%) cases with moderate head Injury and 17 (17.9%) cases with severe head injury in patients those had associated ENT findings. There was no any statistically significant difference in outcome or hospital stay in between the head injuries with and without ENT manifestations (p=0.187) and (p=0.219) respectively.\u0000Conclusion: Skull base tumors are treated based on findings of diagnostic nasal endoscopy and imaging results. CT scans and MRIs are becoming more significant in the diagnosis of diseases. Endoscopic techniques to the skull base were beneficial in treating the malignancy. Chemotherapy can be used as a gold standard first-line treatment with radiation and surgery for significant types of head and neck tumors. immunotherapy-like checkpoint inhibitors targeting PD1 are the second-line treatments of advanced HNSCC. Prospective research and trials will be required in the future.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125898180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of CT scan in modern Neurosurgery","authors":"B. Karmacharya","doi":"10.3126/jbsfn.v2i1.38996","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i1.38996","url":null,"abstract":"<jats:p>NA</jats:p>","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115246565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethmoidal dural Arteriovenous Fistula- A case report","authors":"P. Nepal, Karuna Tamrakar Karki, D. Thapa","doi":"10.3126/jbsfn.v1i1.32231","DOIUrl":"https://doi.org/10.3126/jbsfn.v1i1.32231","url":null,"abstract":"Ethmoidal dural arteriovenous fistulas (dAVF) are a rare type of dAVF present in the anterior cranial fossa. There are usually fed by the ethmoidal artery and drains into superior sagittal sinus. Due to its high flow nature, they are considered a challenging case for surgery and usually present with frontal lobe hematoma or seizure. Here, is a similar case report of a 52-year-old gentleman who presented with sequel of frontal lobe hematoma and was managed surgically with clipping of feeder and excision of fistula.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125149318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Shrestha, Rachana Nakarmi, Ritesh Luitel, S. Paudel
{"title":"Patient profile of patients attending to emergency department of a tertiary neurological and neurosurgical hospital of Nepal: One year experience","authors":"R. Shrestha, Rachana Nakarmi, Ritesh Luitel, S. Paudel","doi":"10.3126/jbsfn.v1i1.32226","DOIUrl":"https://doi.org/10.3126/jbsfn.v1i1.32226","url":null,"abstract":"Introduction: Neurological emergencies are life threatening conditions that arise frequently and have devastating results if not diagnosed and treated quickly with high rates of neurological mortality and morbidity. Being a tertiary neurological center, Upendra Devkota Memorial National Institute of Neurological and Allied Science is a major referral center for neurological diseases. The objective of this study is to assess the types and number of diseases that present to the emergency department of a tertiary neurological center. \u0000Methods: This is a retrospective study conducted in emergency department of national neurosurgical/neurological referral hospital in Kathmandu, from Oct 2018 to Sept 2019. Clinico-epidemiological details of the patients were noted. \u0000Results: The total number of patients presenting to the emergency in one year period were 2995. 58.33% were males and 41.67% were females with male to female ratio of 1:1.4. Majority of the patients (24.91%) were above 60 years of age. Trauma (26.08%) was the major admissions followed by stroke (25.71%) and headache (11.79%). The majority of trauma were road traffic accident (43.02%) followed by fall injury (29.83%) and physical assault (18.96%). Out of the stroke cases, 51.68% were ischemic followed by hemorrhagic stroke 44.55% and transient ischemic attack (3.77%). One thousand eight hundred and ten people were admitted. \u0000Conclusion: The study presents an overview of the patients presenting as neurological emergency. It helps to better plan and devise resources and system in a neurosurgical emergency.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122686053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Message from the Chief Editor Vol.1(1)","authors":"B. Karmacharya","doi":"10.3126/jbsfn.v1i1.32216","DOIUrl":"https://doi.org/10.3126/jbsfn.v1i1.32216","url":null,"abstract":"Brain and Spine Foundation Nepal is a not-for profit organization registered (Registration No. 226156/076/077) on 13th Ashwin 2076. The Foundation aims to work with all those involved in prevention, diagnosis and treatment of brain and spine disorders and diseases. One of the guiding principle of the foundation is dissemination of medical information related to these diseases. \u0000In Nepal, there are two neurosurgical journals being regularly published Nepal Journal of Neuroscience (NJNS, ISSN 1813-1948), official journal of Nepalese Society of Neurosurgeons (NESON) and Eastern Green Neurosurgery (EGN, ISSN 2705-4470), published by Department of Neurosurgery, B and C Medical College and Teaching Hospital, Birtamode. NJNS is being published since January 2004 and EGN is being published since April 2019. However these journals accept articles mainly from neurologists and neurosurgeons. \u0000The objective of any journal is to provide information about various research projects, interaction with own fraternity and to publish scientific articles of research and clinical practice. We at the Foundation believe that the neurological problems should be tackled with multidimensional probe. We focus on awareness programs, information dissemination and involve other healthcare workers like physiotherapists, physiatrists, neuro nurses, emergency physicians, neuro-anaesthesiologists, pain physicians etc. We aim to publish this journal twice a year, on March and on September. \u0000We request all healthcare workers who take care of brain and spine patients to send articles related to their work. You can send case reports, review articles and original articles for publication in this journal.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"250 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116414385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of Carotid doppler in Patients with ischemic stroke","authors":"M. Gyawali, P. Sharma, D. Karki","doi":"10.3126/jbsfn.v2i1.39014","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i1.39014","url":null,"abstract":"Introduction: Stroke is one of the major causes of increased morbidity and death. Large-vessel atherosclerosis of intracranial and extra cranial carotid vessels is an important cause of ischemic stroke. This research was undertaken to study the carotid Doppler findings in patients with acute ischemic stroke.\u0000Methods: A hospital-based prospective cross-sectional study was conducted from January 2020 till December 2020 in the department of Radio diagnosis and Imaging at Manipal Teaching Hospital, Pokhara, Nepal. Neuro-imaging and carotid Doppler findings in patients with ischemic stroke were studied. Data analysis was done using SPSS 20.\u0000Results: The mean age of subjects with ischemic stroke was 64 ± 13.4 years with the majority of cases in the age group of 51-70 years of age with male predominance (M: F= 3: 2). Lacunar infarcts (34.2%) were the most common findings followed by MCA infarct (30%) and ACA infarct (10.8%). Carotid plaques were seen in 43.3% patients. Bilateral ICA atheromatous plaque was seen in 48.1% of patients. Carotid bulb was the common site for plaque formation. Type III plaque was the commonest type. Significant ICA stenosis > 50 % was observed in 24.2% patients. Age >50 years, male sex, smoking, hypertension, diabetes, and hyperlipidemia were important risk factors.\u0000Conclusion: Carotid artery Doppler demonstrated atherosclerotic plaques and significant stenosis in patients with ischemic stroke. Increasing age >50 years, male sex, smoking, hypertension, diabetes, and hyperlipidemia were associated with an increased rate of atherosclerosis, carotid stenosis and ischemic stroke.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115231306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Prasad, S. Bishokarma, S. Koirala, D. N. Gongal
{"title":"A study of vasospasm in traumatic brain injury with subarachnoid hemorrhage","authors":"S. Prasad, S. Bishokarma, S. Koirala, D. N. Gongal","doi":"10.3126/jbsfn.v2i1.39012","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i1.39012","url":null,"abstract":" Introduction: Cerebral vasospasm (CV) is common following subarachnoid hemorrhage (SAH). However, its impact on neurological outcome, especially in head trauma, has not been yet elucidated. Controversy exists about the true relationship between TBI, SAH and Traumatic Vasospasm. Hence, this study aims to determine the association of vasospasm in TBI with SAH.\u0000Methods: This is Observational cross-sectional study with 124 head injury patients. 31 patients were excluded. Transcranial Doppler ultrasonography (TCD) was conducted on daily bases in all patients with traumatic brain injury (TBI). Vasospasm in the MCA and ACA was defined by a mean Flow velocity (FV) exceeding 120 cm/s and three times the mean FV of the ipsilateral ICA.\u0000Results: Among 93 included patients, 72 (77%) were male and 21 (23%) were female. Mean age was (35+10) years. Mean GCS score was (11+4.1). 61 (66%) patients suffered with severe head injury. Vasospasm was detected in 45 % (42) of the total patients. Vasospasm was severe among 4.3% (4 patients), and moderate among 65.6% (61 patients). Association was found between severity of trauma and the severity of vasospasm in MCA (r= 0.41 and 0.38, p value< 0.005) and in ACA (r =0.25, p value < 0.005). The presence of SAH is highly correlated with an amplified incidence of vasospasm. The patients who developed vasospasm, 55% (23) had SAH whereas 45% (19) didn’t have SAH, the corresponding p value is 0.04 which is significant.\u0000Conclusion: The high incidence of vasospasm is associated with SAH in severe TBI patients. Further studies are recommended to determine predictors of vasospasm in TBI patients with SAH.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114224155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Sharma, Subita Lalchan, Subhash Kc, M. Gyawali, N. Kushwaha
{"title":"Impact of gender and age on inner diameter of arteries forming circle of Willis assessed by multidetector CT","authors":"P. Sharma, Subita Lalchan, Subhash Kc, M. Gyawali, N. Kushwaha","doi":"10.3126/jbsfn.v2i1.39016","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i1.39016","url":null,"abstract":"Introduction: The circle of Willis (CoW), which is located at the base of the brain is the most important anastomosis between the internal carotid and vertebral system. It is the main distributor of blood to the brain.\u0000Methods: CT head and CT angiography were performed using standard scan parameters. Only the tests with normal radiological reports and appropriate technical standards were included in the study. Component of circle of Willis: Anterior cerebral artery (ACA), Middle cerebral artery (MCA), Anterior communicating artery (Acom), Posterior Communicating artery (PCom), Basilar artery (BA) and Posterior cerebral artery (PCA) were identified and their internal diameter were measured.\u0000Results: Basilar artery was the artery with largest internal diameter with mean diameter of 2.5 ±0.52 mm. Men had significantly larger arterial sizes than women in all of the intracranial arteries examined except right PCom, Left PCom and right MCA. Right ACA had significantly larger internal diameter in <40 years’ age group. BA, left PCA, Bilateral PCom and MCA showed larger diameter in age group ≥40 years.\u0000Conclusion: Men had significantly larger arterial sizes than women in all of the intracranial arteries examined except right PCom, Left PCom and right MCA.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126337967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Yogi, J. Neupane, Aabishkar Bhattarai, B. Karki, B. Pun
{"title":"Factors predicting pneumonia in patients admitted with spontaneous supratentorial intracerebral hemorrhage in western region of Nepal","authors":"S. Yogi, J. Neupane, Aabishkar Bhattarai, B. Karki, B. Pun","doi":"10.3126/jbsfn.v2i1.39015","DOIUrl":"https://doi.org/10.3126/jbsfn.v2i1.39015","url":null,"abstract":"Introduction: Despite the well-documented association of stroke-associated complications and infections with increased mortality, morbidity and worse long-term outcome, there are only limited data available on independent predictors of pneumonia in patients with acute intracerebral hemorrhage. In this study, our objective was to evaluate risk factors and comorbid conditions associated with the diagnosis of hospital acquired pneumonia in the patients admitted with spontaneous intracerebral hemorrhage and to determine the independent predictors of pneumonia in these patients.\u0000Methods: A retrospective analysis was done in patients admitted in Intensive Care Unit of Nepalgunj Medical College with spontaneous intracerebral hemorrhage. Various clinic-demographic parameters were tested for association with pneumonia or no pneumonia group using chi square or student’s “t” test.\u0000Results: A total of 117 patients, 86 men (73.5%) and 31 women (26.5%) with spontaneous intracerebral hemorrhage were included in the study. There were 36 (30.77%) patients with pneumonia. The association Diabetes mellitus (p<0.01), COPD (p<0.01), smoking (p<0.01), mean GCS (p<0.01), ICH volume (p=0.01), ICH score (p<0.01), operated status (p<0.01), Ganglionic (<0.01), Brain stem (p=0.03) and Ventricular (p=0.01) location of hematoma was statistically significant with pneumonia. Outcome in terms of MRS at discharge was also poorer for patients with pneumonia (p=0.01).\u0000Conclusion: Diabetes mellitus, COPD, mean GCS, ICH volume, ICH score, operated status, higher MRS score were associated with increased risk of pneumonia in ICH. Similarly, ganglionic hematoma, brainstem hematoma and those having intraventricular hemorrhages are also associated with increased risk of pneumonia. Outcome in patients in terms of MRS were also poorer in those who had pneumonia.","PeriodicalId":312899,"journal":{"name":"Journal of Brain and Spine Foundation Nepal","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122418242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}