Journal of Basic and Applied Zoology最新文献

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Larval salivary glue protein heterosis and dosage compensation among the interspecific F1 hybrids of Drosophila nasuta nasuta and Drosophila nasuta albomicans 鼻果蝇和白果蝇F1种间杂种幼虫唾液胶蛋白的杂种优势及剂量补偿
Journal of Basic and Applied Zoology Pub Date : 2016-01-01 Epub Date: 2016-02-15 DOI: 10.1016/j.jobaz.2015.06.002
Raghavan Prithi, S.R. Ramesh
{"title":"Larval salivary glue protein heterosis and dosage compensation among the interspecific F1 hybrids of Drosophila nasuta nasuta and Drosophila nasuta albomicans","authors":"Raghavan Prithi,&nbsp;S.R. Ramesh","doi":"10.1016/j.jobaz.2015.06.002","DOIUrl":"10.1016/j.jobaz.2015.06.002","url":null,"abstract":"<div><p>Reciprocal cross effects with respect to larval salivary secretory protein levels were studied in the interspecific fertile reciprocal hybrids by crossing <em>Drosophila nasuta nasuta, and Drosophila nasuta albomicans.</em> These proteins are produced copiously during the third larval instar stage and are believed to play a role in the attachment of pupa to the substratum prior to pupariation as well as in insect immunity. Quantitative variations were encountered among the reciprocal hybrids. Significant heterosis was observed between <em>D. n. nasuta</em> and the F<sub>1</sub> hybrid female of a cross between <em>D. n. albomicans</em> female and <em>D. n. nasuta</em> male (21.39%) while the F<sub>1</sub> hybrids of a cross between <em>D. n. nasuta</em> female and <em>D. n. albomicans</em> male showed a marginal increase (4.24%) from the mid parent level. The glue secretions were correlated to total cell number but independent of gland size. SDS PAGE revealed a considerable heterosis with respect to X-linked protein fractions. Here we report sex specific biochemical heterosis. However the X-linked fractions undergo dosage compensation in both parents and hybrids indicating strict regulatory control.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"73 ","pages":"Pages 13-19"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78754634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Viable mass production method for cotton pink bollworm, Pectinophora gossypiella (Saunders) 棉铃虫Pectinophora gossypiella (Saunders)可行的规模化生产方法
Journal of Basic and Applied Zoology Pub Date : 2016-01-01 Epub Date: 2016-02-15 DOI: 10.1016/j.jobaz.2015.09.004
B. Dhara Jothi , V. Chinna Babu Naik , S. Kranthi , K.R. Kranthi , R. Valarmathi
{"title":"Viable mass production method for cotton pink bollworm, Pectinophora gossypiella (Saunders)","authors":"B. Dhara Jothi ,&nbsp;V. Chinna Babu Naik ,&nbsp;S. Kranthi ,&nbsp;K.R. Kranthi ,&nbsp;R. Valarmathi","doi":"10.1016/j.jobaz.2015.09.004","DOIUrl":"10.1016/j.jobaz.2015.09.004","url":null,"abstract":"<div><p>Cotton seed based artificial diet has been standardized for continuous rearing of pink bollworm <em>Pectinophora gossypiella</em> (Saunders) at the Central Institute for Cotton Research, Regional Station, Coimbatore. The ingredients of the diet are easily available and are cost effective. Basic ingredients of the diet are cotton seed flour (processed) and chick pea flour, Carbohydrate, Protein, Fat sources, multi vitamin, antimicrobial agents and agar as thickening agent are used as other ingredients. Micro centrifuge tubes with lid were used as rearing containers. Individual neonate larvae were released on each piece of the diet inside the micro centrifuge tube and the lids were closed. This prevented larval escape, retaining them inside the tubes and also prevented diet dehydration. The recovery of insect reared on diet was recorded as 95.56%. Egg hatchability and adult emergence were 100% while pupal malformation was nil. Eggs, larval and pupal periods were recorded as 4.8<!--> <!-->±<!--> <!-->0.632, 25.10<!--> <!-->±<!--> <!-->0.994 and 7.9<!--> <!-->±<!--> <!-->0.88<!--> <!-->days, respectively. Larval and pupal weights were recorded as 21.40<!--> <!-->mg<!--> <!-->±<!--> <!-->3.63, 18.00<!--> <!-->mg<!--> <!-->±<!--> <!-->2.73, respectively.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"73 ","pages":"Pages 9-12"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.09.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84938261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Cardiac disorders and mode of action of the Egyptian scorpion venom Androctonus bicolor on isolated toad’s heart 埃及蝎子毒液对离体蟾蜍心脏的作用模式及心脏疾患
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-11-23 DOI: 10.1016/j.jobaz.2015.09.003
Mohamed A. Abdel-Rahman , Aya S. Ayed , Yousra Abdel-Mottaleb , Mohamed Alaa A. Omran , Zohour I. Nabil
{"title":"Cardiac disorders and mode of action of the Egyptian scorpion venom Androctonus bicolor on isolated toad’s heart","authors":"Mohamed A. Abdel-Rahman ,&nbsp;Aya S. Ayed ,&nbsp;Yousra Abdel-Mottaleb ,&nbsp;Mohamed Alaa A. Omran ,&nbsp;Zohour I. Nabil","doi":"10.1016/j.jobaz.2015.09.003","DOIUrl":"10.1016/j.jobaz.2015.09.003","url":null,"abstract":"<div><p>Scorpion venom is a complex mixture of components with various pharmacological and toxicological effects. It is characterized by the presence of a large number of toxins that specifically interact with ion channels of excitable cells. The Egyptian scorpion <em>Androctonus bicolor</em> belongs to the family of Buthidae and until now no information is available about the effect of its venom on cardiac muscles. Using an <em>in vitro</em> approach, cardiotoxicity and mode of action of <em>A. bicolor</em> venom on isolated toad’s heart were investigated. Direct application of scorpion venom (0.5<!--> <!-->μg/ml) into isolated toad’s heart induced a remarkable bradycardia concomitant with a protraction in the conduction time (P–R interval). In the meantime, a significant increase in the R-wave amplitude (ventricular contraction) was noticed after 5<!--> <!-->min of venom perfusion. Various cases of cardiac disorders were recorded such as sinus arrhythmias, ectopic beats and different degrees of heart block. Through using different autonomic and ion channel blockers, the possible mechanism of action of <em>A. bicolor</em> venom on isolated toad’s heart was revealed. The application of both atropine (4<!--> <!-->μg/ml) and verapamil (5<!--> <!-->μg/ml) could not alleviate the pronounced negative chronotropic and positive inotropic effects. Meanwhile, a significant decrease in the R-wave amplitude was observed after propranolol (5<!--> <!-->μg/ml) application. In conclusion, our findings indicate that the venom of <em>A. bicolor</em> directly influenced the cardiac electrical activity of toads through β-adrenergic receptors. The direct effect of this venom on cardiac tissues may significantly contribute in the development of several cardiotoxic effects following scorpion sting.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 137-144"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82256141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Ecotoxicological impacts of zinc metal in comparison to its nanoparticles in Nile tilapia; Oreochromis niloticus 金属锌纳米颗粒对尼罗罗非鱼的生态毒理学影响Oreochromis niloticus
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-09-18 DOI: 10.1016/j.jobaz.2015.08.003
Amr adel Abdel-Khalek, Mohamed Kadry, Aliaa Hamed, Mohamed-Assem Marie
{"title":"Ecotoxicological impacts of zinc metal in comparison to its nanoparticles in Nile tilapia; Oreochromis niloticus","authors":"Amr adel Abdel-Khalek,&nbsp;Mohamed Kadry,&nbsp;Aliaa Hamed,&nbsp;Mohamed-Assem Marie","doi":"10.1016/j.jobaz.2015.08.003","DOIUrl":"10.1016/j.jobaz.2015.08.003","url":null,"abstract":"<div><p>Nile tilapia; <em>Oreochromis niloticus</em> was used as a bio-indicator to evaluate the impact of zinc metal. The potential impacts of zinc nanoparticles (Zn NPs) on aquatic ecosystems have attracted special attention due to their unique properties. The present investigation was designed to evaluate and compare between the possible ecotoxicological effects of zinc bulk particles (BPs) and Zn NPs on <em>O. niloticus.</em> LC50/96<!--> <!-->h of Zn (BPs &amp; NPs) were (1.36 &amp; 0.18<!--> <!-->g/l), respectively. The concentration equivalent to 1/2 LC50/96<!--> <!-->h of Zn BPs (0.68<!--> <!-->g/l) and Zn NPs (0.09<!--> <!-->g/l) was selected for 7, 14 &amp; 28<!--> <!-->days. Exposure of the studied fish to 1/2 LC50/96<!--> <!-->h of Zn BPs &amp; Zn NPs elicited a significant decrease in total lipids, total protein and globulin contents, coinciding with an enhancement in serum glucose, albumin, creatinine and uric acid concentrations, as well as activities of liver enzymes named AST, ALT, and ALP after the experimental periods. Moreover, Zn NPs significantly induced an increase in liver and gills glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels and with concomitant decreases in the liver and gill (GSH) level in the studied fish. The adverse effects of NPs were observed to be time dependent with increasing extent during the studied time intervals, while fish groups treated with BPs showed more or less time dependent effects. In conclusion, Zn NPs have stronger toxic impacts than that of the Zn BPs, and increased with prolonged exposure time.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 113-125"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91029907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Chronic exposure to low intensity natural light blocks spawning in the cichlid fish Oreochromis mossambicus 长期暴露在低强度自然光下会阻碍凤尾鱼的产卵
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-11-23 DOI: 10.1016/j.jobaz.2015.09.005
C.B. Ganesh , V.R. Mokashi
{"title":"Chronic exposure to low intensity natural light blocks spawning in the cichlid fish Oreochromis mossambicus","authors":"C.B. Ganesh ,&nbsp;V.R. Mokashi","doi":"10.1016/j.jobaz.2015.09.005","DOIUrl":"10.1016/j.jobaz.2015.09.005","url":null,"abstract":"<div><p>The tilapia <em>Oreochromis mossambicus</em> shows a series of short ovarian cycles throughout the year. The present study examined the impact of low intensity ambient natural light (ANL) in indoor environment on the follicular developmental status and the spawning cycle of <em>O. mossambicus</em>. The stripped fish (eggs removed manually, day 1) held outdoors in direct natural light (DNL) successfully spawned between 24 and 28<!--> <!-->days, whereas those reared in ANL failed to spawn despite the presence of a significantly higher number of stage V (vitellogenic) follicles in the ovary compared to that of DNL during the prespawning phase (day 23). These fish did not spawn even up to day 50. The profile of serum levels of cortisol did not show a significant difference between the two experimental conditions. On the other hand, the serum levels of estradiol (E<sub>2</sub>) were significantly higher during vitellogenic phase (day 18) compared to previtellogenic phase (day 12) in both experimental fish. In fish exposed to DNL, the serum levels of E<sub>2</sub> decreased prior to spawning, but remained significantly higher in fish exposed to ANL, suggesting the possible absence of a steroidogenic shift prior to spawning. The results reveal that lack of a critical environmental cue such as the light signal might affect the spawning cycle by causing alterations in the ovarian steroidogenic activity, for the first time in a continuously breeding fish such as <em>O. mossambicus</em>.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 145-153"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.09.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83091004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Malathion acute toxicity in tadpoles of Duttaphrynus melanostictus, morphological and behavioural study 马拉硫磷对黑腹小蝌蚪的急性毒性、形态学和行为学研究
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-02-26 DOI: 10.1016/j.jobaz.2015.01.004
M. David, R.M. Kartheek
{"title":"Malathion acute toxicity in tadpoles of Duttaphrynus melanostictus, morphological and behavioural study","authors":"M. David,&nbsp;R.M. Kartheek","doi":"10.1016/j.jobaz.2015.01.004","DOIUrl":"10.1016/j.jobaz.2015.01.004","url":null,"abstract":"<div><p>The present study was undertaken to evaluate the median lethal concentration (LC<sub>50</sub>), morphological deformities and changes in behavioural responses caused by commercial formulations of malathion on <em>Duttaphrynus melanostictus</em> tadpoles. The LC<sub>50</sub> value was found to be 7.5<!--> <!-->mg/l and ability of malathion to cause morphological anomalies and changes in behavioural responses in tadpoles were studied at sublethal concentrations of 0.5<!--> <!-->mg/l (1/15th), 0.75<!--> <!-->mg/l (1/10th) and 1.5<!--> <!-->mg/l (1/5th) for a duration of 5<!--> <!-->days. The morphological defects and changes in behavioural responses like notochord curvature and loss of fright response respectively were witnessed as an important conduct; in addition, other symptoms under both the parameters were known to be time (i.e. developmental stage) and concentration dependent thereby acknowledging the direct cause of damage due to malathion. Thus, based on the present study, care must be taken when this chemical is in use at agricultural sites especially nearby aquatic ecosystems.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81071761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Ameliorative effect of the sea cucumber Holothuria arenicola extract against gastric ulcer in rats 海参沙棘提取物对大鼠胃溃疡的改善作用
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-04-11 DOI: 10.1016/j.jobaz.2015.03.001
Sohair R. Fahmy, Mahmoud A. Amer, Mohannad H. Al-killidar
{"title":"Ameliorative effect of the sea cucumber Holothuria arenicola extract against gastric ulcer in rats","authors":"Sohair R. Fahmy,&nbsp;Mahmoud A. Amer,&nbsp;Mohannad H. Al-killidar","doi":"10.1016/j.jobaz.2015.03.001","DOIUrl":"10.1016/j.jobaz.2015.03.001","url":null,"abstract":"<div><p><em>Holothuria arenicola</em> is the most important and abundant sea cucumber species in the Mediterranean Sea on the Egyptian coast. This work aimed to investigate the prophylactic and the curative effects of <em>H. arenicola</em> extract HaE (200<!--> <!-->mg/kg) on gastric mucosal damage following indomethacin and cold stress in healthy rats. Sixty-four rats were randomly divided into four main groups. Rats of the first group (8 rats/group) were administered distilled water orally (control group), rats of the second group (8 rats/group) were administered single oral dose of indomethacin (150<!--> <!-->mg/kg) and exposed to cold stress (4<!--> <!-->±<!--> <!-->1<!--> <!-->°C) for 30<!--> <!-->min to induce gastric ulcer (GU) model (ulcer group), rats of the third group, prophylactic group (24 rats/group) were treated with HaE and/or ranitidine (RAN) and then exposed to GU and rats of the fourth group, curative group (24 rats/group) were exposed firstly to GU and then treated with HaE and/or RAN. The results clearly indicate that pre-treatment with HaE and/or ranitidine significantly decreases the ulcer index, showing 72.50%, 53.11% and 80.56% ulceration inhibition, respectively. However, post-treatment with HaE and/or ranitidine significantly decreases the ulcer index, showing 51.66%, 62.41% and 67.78% ulceration inhibition, respectively. The results also showed that pre and post-treatment with HaE and/or RAN significantly decreased gastric malondialdehyde (MDA) level and enhanced reduced glutathione (GSH), catalase (CAT), glutathione-S-transferase (GST) and superoxide dismutase (SOD) levels. The results clearly indicate that pre-treatment with HaE is preferable.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 16-25"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76942960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Anti-osteoporotic effect of medical herbs and calcium supplementation on ovariectomized rats 中药及补钙对去卵巢大鼠的抗骨质疏松作用
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-05-20 DOI: 10.1016/j.jobaz.2015.04.007
Magda M. Elkomy, Fahmy G. Elsaid
{"title":"Anti-osteoporotic effect of medical herbs and calcium supplementation on ovariectomized rats","authors":"Magda M. Elkomy,&nbsp;Fahmy G. Elsaid","doi":"10.1016/j.jobaz.2015.04.007","DOIUrl":"10.1016/j.jobaz.2015.04.007","url":null,"abstract":"<div><p>Estrogen deficiency and insufficient calcium in diet in postmenopause create serious problems with resultant osteoporosis and fractures. In the present study, forty adult albino rats weighting 200–220<!--> <!-->g were used and divided into five groups. Group 1, control group included non-ovariectomized untreated rats. Group 2, ovariectomized)OVX) rats. Group 3, OVX rats daily received CaCO<sub>3</sub> (27<!--> <!-->mg/kg<!--> <!-->b.w.). Group 4, OVX rats daily received a mixture of herbs (sage, rosemary and thyme) (30<!--> <!-->g/kg<!--> <!-->b.w.). Group 5, OVX rats daily received both herb mixture and CaCO<sub>3</sub>. The results showed significant decrease in serum calcium (Ca), inorganic phosphorus (P), total proteins (TP), calcitonin, bone mass density (BMD), reduced glutathione (GSH) and catalase (CAT) in OVX rats compared to the control group. While a significant increase in serum parathyroid hormone (PTH), osteocalcin, alkaline phosphatase (ALP) and acid phosphatase (ACP) were recorded. Also the recorded data showed increases in femur, tibia and vertebral lipid peroxidation (MAD) content and the activities of acid phosphatase and alkaline phosphatase in the ovariectomized rats. On the other hand, when OVX rats were fed on sage, rosemary and thyme supplemented diets or CaCO<sub>3</sub> in a single or in combination, the data recorded a significant improvement in all the above mentioned parameters. Finally, the results of this study indicated that the combination of common herbs (sage, rosemary and thyme) with calcium carbonate, was more effective in reduction and prevention of osteoporosis in ovariectomized rats. So, it can be concluded that consumption of mixed herbs supplemented diets might be considered as a functional food for retarding risks of osteoporosis associated with estrogen deficiency in OVX states.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 81-88"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.04.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84622064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 46
Renoprotective effect of Mangifera indica polysaccharides and silymarin against cyclophosphamide toxicity in rats 芒果多糖和水飞蓟素对环磷酰胺毒性大鼠肾保护作用
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-12-10 DOI: 10.1016/j.jobaz.2015.09.006
Ahmed I. Amien , Sohair R. Fahmy , Fathi M. Abd-Elgleel , Sara M. Elaskalany
{"title":"Renoprotective effect of Mangifera indica polysaccharides and silymarin against cyclophosphamide toxicity in rats","authors":"Ahmed I. Amien ,&nbsp;Sohair R. Fahmy ,&nbsp;Fathi M. Abd-Elgleel ,&nbsp;Sara M. Elaskalany","doi":"10.1016/j.jobaz.2015.09.006","DOIUrl":"10.1016/j.jobaz.2015.09.006","url":null,"abstract":"<div><p>The present study aims to evaluate the possible protective role of polysaccharides extracted from the Egyptian mango <em>Mangifera indica</em> L. (MPS) and silymarin against cyclophosphamide (CP) nephrotoxicity in male albino rats. Male rats were randomly divided into, control group (administered distilled water orally for 10<!--> <!-->days) and MPS (500, 1000<!--> <!-->mg/kg, p.o.) and/or silymarin (150<!--> <!-->mg/kg, p.o.) treated groups for 10<!--> <!-->days. In the last 5<!--> <!-->days of treatment rats were administered CP (150<!--> <!-->mg/kg, i.p). The MPS revealed significant prophylactic effect against kidney injury induced by CP as demonstrated by enhancement of the kidney function via decreasing serum creatinine, urea and uric acid. Treatment of rats with MPS extract and/or silymarin significantly increased the level of reduced glutathione (GSH) and superoxide dismutase (SOD) activity while decreased the level of total malondialdehyde (MDA) and glutathione-S-transferase (GST). Also, histopathological examinations confirmed the protective efficacy of MPS and/or silymarin against CP nephrotoxicity. In conclusion, the obtained results of the present study support the protective antioxidant role of MPS and/or silymarin against CP-induced kidney disorder in rats.</p></div>","PeriodicalId":31288,"journal":{"name":"Journal of Basic and Applied Zoology","volume":"72 ","pages":"Pages 154-162"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jobaz.2015.09.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88897147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Temperature dependence of cardiac sarcoplasmic reticulum and sarcolemma in the ventricle of catfish (Clarias gariepinus) 鲶鱼心室肌浆网和肌膜的温度依赖性
Journal of Basic and Applied Zoology Pub Date : 2015-10-01 Epub Date: 2015-06-18 DOI: 10.1016/j.jobaz.2015.05.004
El-Sabry Abu-Amra, Mohamed F. El-Sayed, Ahmed Badr
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引用次数: 3
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