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Optical Trapping and Optical Micromanipulation XVIII最新文献

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3D Cell-Rotation using Multi-Core Fiber-based Lab-on-a-Chip and Wavefront Shaping 基于多芯光纤的芯片实验室和波前整形的三维细胞旋转
Optical Trapping and Optical Micromanipulation XVIII Pub Date : 2021-08-01 DOI: 10.1117/12.2596236
J. Czarske
{"title":"3D Cell-Rotation using Multi-Core Fiber-based Lab-on-a-Chip and Wavefront Shaping","authors":"J. Czarske","doi":"10.1117/12.2596236","DOIUrl":"https://doi.org/10.1117/12.2596236","url":null,"abstract":"Optical dual-beam trapping is a vital tool in biology. However, a precise rotation of large cells in 3D about arbitrary axes has not been reported yet with dual-beam traps. We introduce a novel multi-core fiber-based dual-beam optical trap using wavefront shaping. Real-time controlled rotation of HL60 cells for cancer studies is demonstrated. For the first time, the orientation of the cell can be precisely controlled about all 3D axes in a dual beam trap. Multi-core fibers provide much higher flexibility beyond the bulky optics, enabling lab-on-a-chip applications and can be easily integrated for applications like non-invasive refractive index tomography and cell-elasticity measurements.","PeriodicalId":311295,"journal":{"name":"Optical Trapping and Optical Micromanipulation XVIII","volume":"247 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123390434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opto-Thermo-Electrohydrodynamic Tweezers: Towards On-chip Single-Molecule Trapping and Analysis 光-热-电-水动力镊子:芯片上的单分子捕获和分析
Optical Trapping and Optical Micromanipulation XVIII Pub Date : 2021-08-01 DOI: 10.1117/12.2595509
J. Ndukaife, Chuchuan Hong, Sen Yang
{"title":"Opto-Thermo-Electrohydrodynamic Tweezers: Towards On-chip Single-Molecule Trapping and Analysis","authors":"J. Ndukaife, Chuchuan Hong, Sen Yang","doi":"10.1117/12.2595509","DOIUrl":"https://doi.org/10.1117/12.2595509","url":null,"abstract":"The trapping and dynamic manipulation of nanoscale biological molecules such as proteins and exosomes using the conventional optical tweezer technology have been met with challenges. This arises because of the substantial optical intensity required, which poses photo-induced damage to the biomolecules. In this talk, I will introduce a new kind of optically controlled nanotweezers termed Opto-Thermo-Electrohydrodynamic Tweezers (OTET) that enables the stable trapping and dynamic manipulation of sub-10 nm biomolecules at locations that are several microns away from the high-intensity laser focus, where they experience both negligible photothermal heating and light intensity. \u0000This novel non-invasive optical nanotweezer is expected to open new horizons in life science and medicine by offering an unprecedented level of control of tiny nano-sized biological objects in solution without photo-induced damage.","PeriodicalId":311295,"journal":{"name":"Optical Trapping and Optical Micromanipulation XVIII","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127211401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectral compression of narrowband single photons 窄带单光子的光谱压缩
Optical Trapping and Optical Micromanipulation XVIII Pub Date : 2021-08-01 DOI: 10.1117/12.2594687
Xi Jie Yeo, C. Kurtsiefer, M. Seidler, A. Ceré
{"title":"Spectral compression of narrowband single photons","authors":"Xi Jie Yeo, C. Kurtsiefer, M. Seidler, A. Ceré","doi":"10.1117/12.2594687","DOIUrl":"https://doi.org/10.1117/12.2594687","url":null,"abstract":"We report an experimental demonstration of spectral compression performed on heralded 795 nm single photons with narrow spectral bandwidths about 3 times larger than the corresponding atomic transitions, generated through four-wave mixing in cold Rubidium-87 atoms. This scheme uses an asymmetric cavity as a dispersion medium to spread out the photon temporally, and subsequently a phase modulator, to modify the spectral energy distribution of the photons. The spectral bandwidth of the photons was compressed by a factor of 2.6, from 20.6 MHz to less than 8 MHz, almost matching the corresponding atomic transition linewidth of 6 MHz. The spectral compression scheme can potentially be adapted to a wide range of wavelengths and spectral widths.","PeriodicalId":311295,"journal":{"name":"Optical Trapping and Optical Micromanipulation XVIII","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116817431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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