Medical Journal of Western Black Sea最新文献

{"title":"Yetmiş Beş Yaş Üstü Metastatik Mide Kanserli Hastalarda Hemoglobin, Albümin, Lenfosit, Platelet (HALP) Skoru ile Geriatrik Nütrisyonel İndeks (GNRI) ve Prognoz Arasındaki İlişki","authors":"Serkan Menekşe, Engin Kut","doi":"10.29058/mjwbs.1198056","DOIUrl":"https://doi.org/10.29058/mjwbs.1198056","url":null,"abstract":"Aim: Gastric cancer (GC) is a common cancer with high mortality. Stage is the most important predictor \u0000of prognosis. But the clinical course of patients who are at the same stage may be different. Therefore, \u0000other prognostic markers other than stage are needed. Hemoglobin, albumin, lymphocyte and platelet \u0000(HALP) score and geriatric nutritional risk index (GNRI) related with prognosis in many malignancies, \u0000but their relationship to prognosis in patients with GC with advanced age is unknown. For this reason, \u0000we retrospectively analyzed patients older than 75 years, receiving chemotherapy, and metastatic GC. \u0000Material and Methods: We retrospectively analyzed 145 patients with metastatic gastric cancer, older \u0000than 75 years, receiving chemotherapy in secondary level state hospital between 2009 and 2022. \u0000Patients’ gender, age, Eastern Cooperative Oncology Group (ECOG) performance score, diagnosis \u0000dates, follow-up visits, albumin, hemoglobin, lactate dehydrogenase (LDH) levels, white blood cell, \u0000neutrophil, lymphocyte and platelet count, weight (kg), height (cm) values were examined. Using these \u0000values, HALP score, GNRI, and overall survival (OS) were calculated. Then, the relationship of these \u0000parameters with OS was analyzed retrospectively. \u0000Results: The median overall survival (OS) was 8.1 (95% Confidence interval (CI), 7.07 – 9.13) months. \u0000In multivariate analysis, GNRI (0.035) and HALP (p","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"202 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123036705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Red Centaury (Hypericum capitatum): Determination of Phenolic Content, Antioxidant Activity and Investigation of Antimicrobial Efficacy on Clinical Isolates","authors":"Ş. Öztürk, Y. Hazer, Banu Kaskatepe, H. Çölgeçen, M. Kulak","doi":"10.29058/mjwbs.1251370","DOIUrl":"https://doi.org/10.29058/mjwbs.1251370","url":null,"abstract":"Amaç: Bu çalışmada, Kırmızı Kantaron, Hypericum capitatum var. capitatum (H. capitatum) bitkisinin \u0000fenolik içeriğinin ve antioksidan aktivitesinin belirlenmesi, standart suşlar ve klinik izolatlar üzerinde \u0000antimikrobiyal etkisinin araştırılması amaçlanmıştır. \u0000Gereç ve Yöntemler: H. capitatum’un, standart bakteri suşları ile kolistin dirençli Acinetobacter \u0000baumannii (A. baumannii) ve çok ilaca dirençli (ÇİD) A. baumannii klinik izolatları üzerindeki \u0000antimikrobiyal etki düzeylerine sıvı mikrodilüsyon testi (MİK) ile gerçekleştirilmiştir (ISO, 2006). Yüksek \u0000Performanslı Sıvı Kromatografisi (YPSK) ile bazı içerikleri aydınlatılan H. capitatum ekstraktının, tohum, \u0000gövde ve yaprak örneklerinde total fenol içeriği araştırılmıştır. DPPH (2,2-difenil-1-pikrilhidrazil) yöntemi \u0000ile antioksidan etkinlik tayini yapılmıştır. \u0000Bulgular: Metanolle ekstrakte edilen bitkinin, Gram (+) bakterilere karşı Staphylococcus aureus (S.aureus) \u0000ATCC-29213 ve Metisilin dirençli S. aureus (MRSA) ATCC 43300 antimikrobiyal etkinliğinin 16 \u0000(mg/mL) olduğu saptanmıştır. Dirençli A. baumannii klinik izolatlarına karşı, 64-128 mg/mL MİK değerleri \u0000ile etkin olduğu tespit edilmiştir. YPSK ile bitkinin tohum kısmındaki içerikler ise, sırasıyla; şikimik asit \u0000(1720.42 ppm(mg/ml), kafeik asit (52.50 ppm(mg/ml), sinaminik asit, (14.217,61 ppm(mg/ml), rosmarinik \u0000asit (30,90 ppm(mg/ml) olarak belirlenmiştir. H. capitatum kısımlarına göre toplam fenolik madde \u0000miktarlarının, yaprak (155,93 mg/L), gövde (177,85 mg/L) ve tohum (344,22 mg/L) şeklinde farklılık \u0000gösterdiği tespit edilmiştir. DPPH İnhibisyon aktivitesi; tohum (%55.476 mg/mL), gövde (%57.318 mg/ \u0000ml), yaprak (%53.241 mg/ml) BHA (Butil hidroksi anozil) ve BHT (Butil hidroksi tolüen) sırasıyla (%93.77 \u0000ve %88.62) askorbik asit ise (%95.21) olarak belirlenmiştir. \u0000Sonuç: Fenolik içerikçe zengin olduğu görülen H. capitatum’ un, antioksidan etkinlik sonuçları, farklı \u0000kısımlarının metanol ekstreleri orta derecede etkili serbest radikal gideren doğal bir antioksidan kaynağı \u0000olduğunu göstermiştir. Antimikrobiyal etkinlik sonuçları ise, standart suşlar ve özellikle klinikte tedavisinin \u0000zor olduğu bilinen dirençli A. baumannii izolatlarına karşı etkinliğinin umut vaat edici olduğu görülmüştür.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"735 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127785092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Micronucleer and Binucleer Cells Frequencies in Buccal Epithelial Cells of Children Infected with Helicobacter pylori","authors":"Zehra SAFİ ÖZ, Gonca Handan ŞAHAN ÜSTÜNDAĞ, Halime TOPUZ ALTUNTAŞ, Nilüfer ONAK KANDEMİR","doi":"10.29058/mjwbs.1205737","DOIUrl":"https://doi.org/10.29058/mjwbs.1205737","url":null,"abstract":"Amaç: Helicobacter pylori (H. pylori) gastroduodenal inflamasyon, ülser ve atrofik gastrite yol açan \u0000bakteriyel bir patojendir. Mikronüklus (MN)’ lar hücrenin mitoz bölünmesi sırasında ortaya çıkan esas \u0000çekirdeğe dahil olmayan oluşumlardır. Bu çalışmada, H. pylori ile mikronükleer ve binükleer hücre \u0000arasındaki ilişkinin eksfolyatif sitoloji yöntemi ile değerlendirilmesi amaçlanmıştır. \u0000Gereç ve Yöntemler: Bu çalışmada Zonguldak Bülent Ecevit Üniversitesi Uygulama ve Araştırma \u0000Hastanesi Çocuk Gastroenteroloji polikliniğine yaşam kalitesini etkileyecek tarzda ciddi dispeptik \u0000yakınmalarla başvuran ve endoskopik biyopsi yapılan hastalar yer aldı. Biyopsi örnekleri formalinde \u0000fikse edildi ve parafin bloklardan hazırlanan kesitler Hematoksilen & Eozin (H&E) ile boyandı. H. \u0000pylori varlığı açısından ışık mikroskobik olarak değerlendirildi. Biyopsi sonucu sadece H. pylori pozitif \u0000örnekler çalışma grubu (n=30) hiçbir enfeksiyon etkeni saptanmayanlar ise kontrol grubu (n=30) olarak \u0000alındı. Tüm hastalardan alınan yanak epitel hücreleri lamlara yayıldı, % 95’lik etil alkolde fikse edildi ve \u0000Papanicolaou boyama yöntemine göre boyandı. Mikronükleer ve binükleer hücreler iyi boyanmış 1000 \u0000epitel hücrede sayıldı. İstatistiksel değerlendirme SPSS 18.0 (SPSS Inc., Chicago, IL, USA) programı \u0000kullanıldı ve p","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123035276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Akut Pankreatitte Yeni Bir İnflamatuar Belirteç Olarak Ortalama Trombosit Hacmi ve C-Reaktif Protein ile Başvuru Anındaki Ranson Skoru ile İlişkisi","authors":"Baris Karagün, Tayyibe Saler","doi":"10.29058/mjwbs.1228491","DOIUrl":"https://doi.org/10.29058/mjwbs.1228491","url":null,"abstract":"Aim: The study’s aim is to evaluate mean platelet volume (MPV) as a marker of inflammation in patients \u0000with acute pancreatitis (AP) and to analyse the relationships among MPV, CRP (C-reactive protein) and \u0000Ranson’s score. \u0000Material and Methods: In this study, 119 patients with AP (mean age 53.8 ± 18.0 years) and 88 healthy \u0000control group (mean age 53.1 ± 6.8 years) were enrolled. Among the patients with AP, 75 were classified \u0000as having biliary AP, and 44 were classified as having nonbiliary AP. All patients’ demographic data, \u0000clinical and laboratory findings and Ranson’s scores were examined from the hospital’s database. \u0000Results: MPV was significantly lower among patients with AP than among the control group (p = 0.001). \u0000CRP was significantly higher among patients with AP than among the control group (p< 0.001). The \u0000difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When \u0000we compared MPV based on patients’ lengths of hospital stay, there was no significant difference. In \u0000correlation analysis, there was no correlation among CRP, Ranson’s score and serum MPV levels. \u0000Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like \u0000other inflammation markers, MPV might be a useful marker for AP diagnosis.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121413024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Depression, Anxiety and Sleep Quality Scores in Patients with Cervical Disc Herniation: A Study Conducted in Turkey","authors":"A. Uysal, Murat Güntel","doi":"10.29058/mjwbs.1220876","DOIUrl":"https://doi.org/10.29058/mjwbs.1220876","url":null,"abstract":"Aim: Neck pain is one of the most prevalent medical complaints. Chronic pain conditions can lead to \u0000depression, anxiety and sleep problems in individuals. Thus, both the pain itself and the psychiatric \u0000problems it causes impair the quality of life of the patient. Depression and anxiety can also cause changes \u0000in the perception of pain. In this study, we aimed to investigate the effects of cervical disc herniation (CDH), \u0000which causes chronic neck pain, on the level of neck disability, sleep quality, anxiety and depression. \u0000Material and Methods: Patients’ pain intensity, neck disability indexes, depression and anxiety status, \u0000and sleep quality were evaluated using a visual analog scale (VAS), the neck disability index (NDI), \u0000Beck Depression Inventory (BDI), beck anxiety inventory (BAI) and the Pittsburgh Sleep Quality Index \u0000(PSQI), respectively. \u0000Results: We found a statistically significant relationship between CDH and anxiety, depression and sleep \u0000quality. In addition, we found higher levels of pain, anxiety and depression in the group with poor sleep \u0000quality. \u0000Conclusion: For optimal treatment approaches of patients with chronic neck pain, accompanying sleep \u0000disorder, depression and anxiety should also be evaluated.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"233 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116410531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Important Risk Factor for Sudden Cardiac Death: Type 2 Brugada Syndrome","authors":"Burak Acem, Merve Osoydan Satici, S. Özdemir, S. Eroğlu","doi":"10.29058/mjwbs.1209412","DOIUrl":"https://doi.org/10.29058/mjwbs.1209412","url":null,"abstract":"Amaç: Brugada sendromunun hızlı ve doğru teşhisi, semptomatik hastalarda aritmiden kaynaklanan \u0000ani kardiyak ölüm riskinin yüksek olması nedeniyle çok önemlidir. Acil serviste Tip 2 Brugada EKG \u0000paterni tespit edilen bir olguyu, klinik tanı güçlüğü ve nadir görülmesi sebebi ile sunmayı ve tartışmayı \u0000amaçladık. \u0000Olgu: Kırkdokuz yaşında erkek hasta acil servise 45 dakika önce başlayan sol göğüste ve epigastrik \u0000bölgede lokalize sıkıştırıcı tarzda göğüs ağrısıyla başvurdu. Tekrarlayan senkop öyküsü, ailede erken \u0000ölüm hikâyesi mevcuttu. Hız kontrolü sağlandıktan sonra çekilen EKG’sinde kalp tepe atımı 99/dk, V1- \u0000V2 derivasyonlarında ST segmentinde elevasyonu takiben 1mm’den fazla çökme ile karakterize ‘eğer \u0000tipi’ görünüm tespit edildi. \u0000Sonuç: Tip 1 Brugada paterni olan hastalara göre ani kardiyak ölüm açısından daha az riskli olarak \u0000kabul edilse de BrS EKG’si dinamik ve değişkendir, Tip 2 kısa sürede Tip 1’e dönüşebilir; bu nedenle \u0000gözden kaçırılmamalıdır","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129520991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Wrist Circumference (Regional Obesity Versus Local Swelling) in Conservatively Treated Distal Radius Fractures: A Single Center Experience","authors":"E. Özdemir, Ozan Altun, Yılmaz Ergişi, Uygar Daşar, Muhammed Nadir Yalçin","doi":"10.29058/mjwbs.1232968","DOIUrl":"https://doi.org/10.29058/mjwbs.1232968","url":null,"abstract":"Aim: Regional obesity around the wrist due to local excessive fat or local swelling due to edema has not\u0000been studied as a risk factor to predict the possibility of reduction loss during conservative treatment of\u0000distal radius fractures. We aimed to investigate the impact of wrist circumference on reduction loss risk\u0000in conservatively treated distal radius fractures.\u0000Material and Methods: Patients with distal radius fractures who were conservatively in our institution\u0000between January 2021 and December 2021 are retrospectively reviewed. Patients’ demographics, wrist\u0000circumference, radiographic parameters were obtained from hospital registry notes. Wrist circumference\u0000was measured with an unstretchable tape positioned on a line passing from lister tubercle of the distal\u0000radius and distal ulna. The difference in the wrist circumferences between the injured and uninjured\u0000extremities represented local swelling. The association of these factors with reduction loss was\u0000evaluated.\u0000Results: A total of 73 consecutive patients (19 male, 54 female) with a mean age of 61.1 ± 12.9 were\u0000included. There were 18 reduction losses. There was no association with reduction loss between injured\u0000and uninjured wrist circumferences (p>0.05). However, local swelling, initial displacement at dorsal\u0000angulation and radial inclination, presence of dorsal comminution, and accompanying ulnar styloid\u0000fracture were associated with reduction loss (p<0.05). Local swelling had an odd ratio of 6.661 (1.848\u0000– 24.006, p= 0.004).\u0000Conclusion: Excessive local swelling is found to be a risk factor to predict reduction loss in conservative\u0000treatment of distal radius fractures while regional obesity is not.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"61 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127798560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Factors Affecting the Smoking Habit and Fear of COVID-19 Among Faculty of Medicine Students","authors":"Ayşegül TOMRUK ERDEM, Ahmet Hazar Büyükakpinar, Kübra Özaydin, Semih Erol, Enes Karataş, Sinem Edi̇nç, Zeynep Aşik, İlayda Başoğlu, Zeynep Kuru, Veli Mert Büyükdumlu, Ece Tuna, Kadriye Tabak, Ayşen Alay, Farice Beyza Demi̇rel","doi":"10.29058/mjwbs.1143866","DOIUrl":"https://doi.org/10.29058/mjwbs.1143866","url":null,"abstract":"Amaç: Çalışmada amacımız COVID-19 pandemisi sırasında tıp fakültesinde öğrenim gören öğrencilerde \u0000sigara tüketimini etkileyen faktörleri ve bunun COVID-19 korkusu ile ilişkisini belirlemektir. \u0000Gereç ve Yöntemler: Çalışma kesitsel ve tanımlayıcı tipte dizayn edilmiş olup, çalışmaya Zonguldak \u0000Bülent Ecevit Üniversitesi Tıp Fakültesinde öğrenim gören 293 öğrenci katıldı. Öğrencilere hazırlanan \u0000anketler elektronik ortamda iletildi, çalışmaya gönüllü olanlar katıldı. Anket formunda öğrencilerin \u0000sosyodemografik özellikleri, sigara alışkanlıkları sorgulandı, Fagerström nikotin bağımlılık testi ve \u0000COVID-19 Korku Ölçeği kullanıldı. \u0000Bulgular: Çalışmaya dahil olan öğrencilerin %70.6’sı kadın idi. Yaş ortalaması 21.38±04 saptandı. Halen \u0000sigara içen katılımcı oranı %17.7 (n=52) idi. Daha önce hiç sigara içmemiş katılımcıların %7.1’inin \u0000(n=15) pandemi sırasında sigaraya başlamayı düşündüğü öğrenildi. Sigarayı bırakmış katılımcıların \u0000%64.5’i (n=20) pandemi sırasında bu kararı almıştı. Sigarayı bırakanların %54.5’i (n=12) mevcut sağlık \u0000sorunları ve hastalanma kaygısı nedeniyle sigara içmeyi bırakmış ve %74.2’si (n=23) tekrar sigara \u0000içmeyi düşünmemekteydi. Sigara içmeye devam eden ve düşük bağımlılık düzeyine sahip katılımcı \u0000oranı %69.2 (n=36) idi. Pandemi sırasında sigara içen katılımcıların %38.4’ünde (n=20) tüketim miktarında \u0000değişiklik olmazken, %34.6’sında (n=18) tüketimde azalma, %27’sinde (n=14) ise tüketimde \u0000artış olduğu görüldü. Sigara tüketiminin değişmesinde haberlerin, kamu spotlarının, sigara yasağının \u0000rol almadığı belirlendi. Sigara içen ve COVID-19 hastalığı geçirenlerin de sigara ile ilgili fikirlerinde \u0000değişiklik olmadığı belirlendi. Katılımcıların COVID-19 korku puanı ortalaması 18.71± 4.91 olup, korku \u0000düzeyi orta seviyede olarak belirlendi. COVID-19 korku düzeyi kadın katılımcılarda erkek katılımcılara \u0000göre istatistiksel olarak anlamlı düzeyde yüksekti (p=0.001). COVID-19 korku düzeyinin sigara kullanım \u0000özellikleri ve diğer sosyodemografik özellikler ile arasında istatistiksel anlamlı fark bulunmadı (p>0.05). \u0000Sonuç: Katılımcılarda COVID-19 korku düzeyi orta seviyede saptanmış olup, kadın katılımcılarda \u0000daha yüksekti. Sigarayı bırakmış olan öğrencilerin çoğunluğu pandemi sırasında bu kararı vermişti. \u0000Haberlerin, kamu spotlarının, sigara yasağının, COVID-19 geçirmenin sigara içen katılımcılarda \u0000tüketimde değişikliğe yol açmadığı belirlendi.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126492483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Clinicopathological Features in Differentiated Thyroid Carcinomas at 55 Age Cut-Off Point: A Single Center Experience","authors":"N. Bestepe, H. Baser, Ayşegül Aksoy Altınboğa, A. Yalçın, O. Topaloğlu, R. Ersoy, B. Çakır","doi":"10.29058/mjwbs.1201993","DOIUrl":"https://doi.org/10.29058/mjwbs.1201993","url":null,"abstract":"Objectives: The incidence of differentiated thyroid cancer (DTC) has been increasing rapidly in recent years. Patient age at diagnosis is a good prognostic factor for thyroid cancer. DTC is the only malignancy that includes age as part of its staging system. The American Joint Committee on Cancer (AJCC) staging system currently uses 55 years of age as the cutoff point. In this study, we aimed to compare the clinicopathological features of DTC in patients","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"237 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121254009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Patients with Ventilator-Associated Pneumonia Developed in Two Different Intensive Care Units of a Tertiary Hospital","authors":"İlken Uguz, Derya Karasu, Canan Yılmaz, G. Durmus, Ezgi ÜNAL ASAN, S. E. Ozgunay, M. Gamlı","doi":"10.29058/mjwbs.1117289","DOIUrl":"https://doi.org/10.29058/mjwbs.1117289","url":null,"abstract":"Aim: Our purpose is to compare the characteristics and 30-day mortality of ventilator-associated \u0000pneumonia (VAP) patients that developed in two different intensive care units (ICUs) in a tertiary hospital. \u0000Material and Methods: Patients who were over the age of 18 who developed VAP in two different \u0000ICUs of our hospital over two years were included in the study. Acute Physiology and Chronic Health \u0000Assessment II (APACHE II), Sepsis-Related Organ Failure Assessment (SOFA), Glasgow Coma Score \u0000(GCS), Clinical Pulmonary Infection Score (CPIS), infection markers, and 30-day mortality of the \u0000patients were evaluated. Physical conditions of Group 1 and Group 2, hand hygiene rates in ICU, nurse \u0000education level, and hospitalization rate in intensive care units were compared. \u0000Results: A total of 104 patients, 48 being in Group 1 and 56 being in Group 2, were analyzed. There \u0000was no significant difference between the two groups with regards of GKS, SOFA and CPIS scores. \u0000Acinetobacter baumanni was the most common agent in both groups. The hospitalization rate was \u0000found to be significantly higher in Group 2. 30-day mortality was 45.8% in Group 1 and 48.2% in Group \u00002. It was found that a one unit increase in the SOFA hospitalization period reduced the risk of 30-day \u0000mortality. It was determined that a one unit increase in the age ratio in Group 2 increased the risk of \u000030-day mortality 1.085 times, and the increase in the mean SOFA score in all patients and Group 1 \u0000decreased the length of the hospitalization period. \u0000Conclusion: We found a 30-day mortality rate of 47.1% in patients diagnosed with VAP. An increase in \u0000SOFA score increases the risk of 30-day mortality, while a prolonged hospitalization period decreases \u0000the risk of mortality.","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123645028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}