{"title":"Subakut Tiroiditte Prognoz Öngörülebilir mi?","authors":"Ali Saklamaz, Özcan Çi̇ftçi̇","doi":"10.29058/mjwbs.1221562","DOIUrl":null,"url":null,"abstract":"Aim: Subacute thyroiditis (SAT) is a thyroid disease that seriously affects the quality of life for patients \ncaused by acute inflammation of the thyroid gland. Apart from classical acute phase reactants, the values \nand rates obtained from peripheral blood count (mean platelet volume (MPV), neutrophil-to-lymphocyte \nratio (NLR), and platelet-to-lymphocyte ratio (PLR)) values are also accepted as practical indicators \nof systemic inflammation. Our aim in this study is to compare the effects of systemic inflammation \nmarkers and the treatments given in the laboratory tests of our patients with a diagnosis of SAT, on the \nhypothyroid state one year later. \nMaterial and Methods: In this study, which was carried out with a retrospective method, 133 patients \nwere included in the study. The medical data of these patients at the time of SAT diagnosis and one \nyear later were analyzed. 37 patients were in the steroid group and 97 patients were in the nonsteroidal \nanti-inflammatory drug (NSAID) group. \nResults: The male/female ratio was similar in both groups. Female dominance was observed in both \ngroups in patients diagnosed with SAT. The thyroid tests of the groups, which were hyperthyroid at the \nbeginning and euthyroid one year later, were similar between the groups (p>0.05). Both groups had \nan increase in acute phase reactants at baseline (erythrocyte sedimentation rate [ESR] and C-reactive \nprotein (CRP) levels) and normalized after treatment. Neutrophil (p0.05) and \nplatelet (p0.05). \nConclusion: Inflammation markers and treatments applied in SAT patients did not have a significant \neffect on the prognosis","PeriodicalId":309460,"journal":{"name":"Medical Journal of Western Black Sea","volume":"29 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Western Black Sea","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29058/mjwbs.1221562","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Aim: Subacute thyroiditis (SAT) is a thyroid disease that seriously affects the quality of life for patients
caused by acute inflammation of the thyroid gland. Apart from classical acute phase reactants, the values
and rates obtained from peripheral blood count (mean platelet volume (MPV), neutrophil-to-lymphocyte
ratio (NLR), and platelet-to-lymphocyte ratio (PLR)) values are also accepted as practical indicators
of systemic inflammation. Our aim in this study is to compare the effects of systemic inflammation
markers and the treatments given in the laboratory tests of our patients with a diagnosis of SAT, on the
hypothyroid state one year later.
Material and Methods: In this study, which was carried out with a retrospective method, 133 patients
were included in the study. The medical data of these patients at the time of SAT diagnosis and one
year later were analyzed. 37 patients were in the steroid group and 97 patients were in the nonsteroidal
anti-inflammatory drug (NSAID) group.
Results: The male/female ratio was similar in both groups. Female dominance was observed in both
groups in patients diagnosed with SAT. The thyroid tests of the groups, which were hyperthyroid at the
beginning and euthyroid one year later, were similar between the groups (p>0.05). Both groups had
an increase in acute phase reactants at baseline (erythrocyte sedimentation rate [ESR] and C-reactive
protein (CRP) levels) and normalized after treatment. Neutrophil (p0.05) and
platelet (p0.05).
Conclusion: Inflammation markers and treatments applied in SAT patients did not have a significant
effect on the prognosis