Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki最新文献

{"title":"Development of Multifunctional Laboratory in Chip for Molecular Diagnostics of Infections","authors":"N. G. Sandetskaya, Dirk Kulmaher, Christian Cilh","doi":"10.15688/JVOLSU11.2018.1.12","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.12","url":null,"abstract":"In the present research the authors carry out a comparative analysis of the effectiveness of different methods for isolating bacteria from samples using a MinoLyzer device, a MinoCard chip cartridge and polymerase chain reaction (PCR) method.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"5 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72397109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Central and Peripheral Components of Action in Comprehensive Analgesic Activity of New Kappa-Agonist","authors":"V. Batrakov, D. D. Shamshina, A. Ivanov","doi":"10.15688/JVOLSU11.2018.1.5","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.5","url":null,"abstract":"Elimination of the pain syndrome is still an urgent task in various fields of medicine. Therefore, the problem of finding new effective and safe analgesics remains today one of the most important. The research is aimed at comparing the central and peripheral analgesic activity of chemical mixture KOR 205 in an experiment in rats. Based on the results of the experimental work, indicators of the maximum possible effect (MVE%) have been determined. The KOR 205 compound has a more pronounced central analgesic effect, compared with peripheral analgesic activity.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78986287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"About Systems of Telecontrol – Biotechnology Control","authors":"M. Postnova, A. Sklyar","doi":"10.15688/JVOLSU11.2018.1.13","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.13","url":null,"abstract":"Currently, powerful modern poultry farms require built-in logistics with an optimized structure of control and management. Such a system requires formalization and ranking, responding to the tasks of specific divisions of enterprises and poultry farms in general. The analysis of the robots on the Russko-Vysotskaya site shows positive results when the Big Dutchman company introduced the BigFarmNet Manager and AMAKS systems for 11 years of operation of this complex allowing to regulate and control the production processes of egg processing, feeding, drinking, to manage the microclimate of poultry houses in real time from the central office or from a portable personal computer using the Internet.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90680244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ways to Reduce Energy Costs in Poultry Farms","authors":"A. Sklyar, M. Postnova","doi":"10.15688/JVOLSU11.2018.2.13","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.2.13","url":null,"abstract":"Currently, the modern poultry farms are located in regions with different climatic conditions. Thus, the component of the electric power being the base for combined heating and ventilating systems, lighting, and local heating of poultry farms, is great in power engineering on the territory of the Russian Federation. The analysis of energy costs of poultry farms showed that of the estimated options for reducing the cost of electricity for poultry farms, one of the most effective can be an alternative source such as the generation of own electricity. Naturally, for biological production with a continuous technological cycle (poultry farming, for example), seems to be replace about 45-55 % of the needs of the factory and serve as a reserve for the rest, but not cover all 100 % of needs.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87846075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Synopsis of the Genus Phleum L. (Poaceae) in Flora of The Kyrgyz Republic","authors":"Adilet Usupbaev","doi":"10.15688/JVOLSU11.2018.2.2","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.2.2","url":null,"abstract":"On the base of investigation of material kept in Herbarium of flora laboratory (Institute for Biology and Pedology, National Aсademy of Sciences (FRU), a synopsis of the genus Phleum L. (Poaceae) in flora of Kyrgyz Republic with a key for identification of species and short citats is presented. Six species are recognized in Kyrgyz Republic (Phleum phleoides H. Karst., Phleum himalaicum Mez, Phleum paniculatum Huds., Phleum pratense L., Phleum roshevitzii Pavlov, Phleum alpinum L.). Phleumroshevitzii Pavlov newly reported for Kyrgyz Republic (Issyk-Kul Lake depression, Northern Kyrgyzstan). Maps of distribution for species growing in Kyrgyz Republic (Laskov GA., Sultanova BA., 2011) and list of studied specimens are provided. NK - Northern Kyrgyzstan (Chu Valley with adjacent northern macro-slope of Alexander Mountain Range, and the basin of Chon-Kemin River); IK - Issyk-Kul Lake depression (including northern macro-slope of TerskeiAla-Too Mountain Range, southern slope of KungeiAla-Too Mountain Range, basins of Tyup, Jergalan, and Karkyra rivers); CT - Central Tien Shan (basin of the Sary-Dzhaz River); WT - esternTien Shan (Talas and Chatkal valleys together with slopes of adjacent mountain ranges, and Ketmen-Tyube Valley); F - Cis-Ferghanian Kyrgyzstan (edges of the Fergana Valley, with adjacent macro-slopes of Chatkal Mountain Range, Fergana Mountain Range, Turkestan Mountain range, and Alai Mountain System); IT - Inner Tien Shan (the area bounded in the north by Kyrgyz Mt. Ridge, in the southwest by Fergana Mountain Range, and in the south-east by Kokshaal-Too Mountain System); А - Alai Valley (including southern macro-slope of Alai Mts. and northern macro-slope of Trans-Alai Mt. Range); EK - Entire territory of Kyrgyzstan (i. e. species is registered in all of abovementioned regions).\u0000Kyrgyz Republic is located in the centre of Eurasia. The distance to an Indian Ocean is about 3 000 km. The total square is about 198,500 km2. Altitudes are from 410 to 7 439 m above sea level. Over 90 % of the territory is elevated above 1 500 m. About 40 % of nearly uninhabitable: glaciers, permanent snow, rocks, scree, alpine\u0000desert, etc. Ca. 7 % of territory is occupied by the cultural landscape: fields, settlements, roads, and industry (Atlas…1987). Only the main literature sources are cited for species: “Flora URSS” (Ovczinnikov, 1934), “Flora of Kirghiz SSR”(Nikitina, 1950), “Conspectus florae AsiaeMediae” (Gamajunova, 1968), and also the monograph of Tzvelev NN. “Grasses of URSS” (Tzvelev, 1976). The article contains 1 Figures, 1 key for identification of species, and 11 References.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89781143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodology of Validation of In Silico 3D-Models of Pharmacologically Relevant Proteins-Targets","authors":"L. Yanalieva, P. Vasilyev, A. Kochetkov","doi":"10.15688/JVOLSU11.2018.1.16","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.16","url":null,"abstract":"The article studies the development of methodology and results of validation of in silico 3D models of pharmacologically relevant target proteins on the example of protein kinase C theta. Using the IUPHAR / BPS database, information has been found about 5 reference inhibitors PRKCQ, recognized by the world scientific community. According to the received data, 3 most valid PRKCQ models (PDB-codes: 5F9E, 2JED, 4RA5) have been selected, which can later be used for docking of new inhibitors.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90957678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Non-Invasive System to Control Morphogenesis of Planaria as an Alternative Approach to Bioassessment","authors":"Ulyana Vorobyeva, K. Novikov, O. Burlakova, V. Emelyanenko, K. Tiras","doi":"10.15688/JVOLSU11.2018.1.3","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.3","url":null,"abstract":"The published study tests our own chemical luminescence Planaria accompanying regeneration processes in combination with methods of in vivo fixation of their structure using non-invasive computer morphometry. As a result, we propose a new system of online remote control of morphogenesis in Planaria regeneration. This system is promising for primary screening of drugs – proliferation regulators.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77204275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"8-Oxo-2'-Deoxyguanosine - Biomarker, Signal Molecule, Potential Pharmaceutical Agent","authors":"N. Marmiy, D. Esipov","doi":"10.15688/JVOLSU11.2018.1.9","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.9","url":null,"abstract":"The study is devoted to 8-oxo-2'-deoxyguanosine (8-oxo-dG), which is used as a biomarker of oxidative damage to DNA and its associated diseases. The study is based on the hypothesis put forward by the authors about the ability of 8-oxo-dG, which is the main product of DNA oxidation, to act as a signal molecule that activates cell resistance to nonspecific stress and DNA repair. In addition to studying the molecular mechanisms of the action of 8-oxo-dG, the authors have carried out an investigation of the effects that they caused on the organism level.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88533245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Algorithms of Three-Dimensional Reconstructionfor Building a Model of Spatial Distributionof Tissue Properties (on the Exampleof Articular Cartilage)","authors":"M. Grunina, V. Novochadov","doi":"10.15688/JVOLSU11.2018.1.4","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.4","url":null,"abstract":"The paper demonstrates relationship between morphological characteristics of articular cartilage and its functional properties in osteoarthritis. An automated analysis of the sections of the rat articular cartilage has revealed these mutual dependences. An algorithm for assessing the functional properties of cartilage by certain characteristics of its tissue in a natural full-color reconstruction is proposed.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"26 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83477815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Influence of Preliminary Alcoholation on Activity of Microsomal Rat Liver Factions In Vitro","authors":"N. Osadchenko, L. Knyshova, A. M. Dotsenko, A. Tarasov, A. Yakovlev","doi":"10.15688/JVOLSU11.2018.1.11","DOIUrl":"https://doi.org/10.15688/JVOLSU11.2018.1.11","url":null,"abstract":"The present research is devoted to the study of the relationship between the structure of the original synthetic monophenolic antioxidants and their ability to influence the activity of autophagy in tumor cells.","PeriodicalId":30925,"journal":{"name":"Vestnik Volgogradskogo Gosudarstvennogo Universiteta Seria 11 Estestvennye Nauki","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75501583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}