Asian Journal of Hospital Pharmacy最新文献

{"title":"The science and art of biostatistics: a comprehensive overview","authors":"Akanksha Mishra, Mohd. Maruf Khan","doi":"10.38022/ajhp.v4i2.86","DOIUrl":"https://doi.org/10.38022/ajhp.v4i2.86","url":null,"abstract":"Biostatistics is the area that involves the application of statistical methods to biological and health-related research and draw out valid conclusion from the obtained data. Statistics are essential to clinical trials and the drug development process, from trial design to protocol preparation. Providing a basic awareness of statistical concerns can help maintain the credibility of a clinical trial. Biostatistics is used at every stage of clinical research, including trial design, protocol development, data tracking and management, data processing, and trial reporting. This article deals with bringing in frame the basic biostatistical concepts that are significant and convenient in analyzing various types of data observations that includes the types of data, measure of central tendency, measure of dispersion, parametric and non-parametric test. Other parameters, such as the normal distribution, sample size computation, significance level, null and alternate hypothesis, and statistical significance test, are thoroughly discussed with appropriate illustrations. The review also mentions the software applications and websites helpful for statistical computations.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"162 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient counselling mediated by clinical pharmacists on hypertensive patients","authors":"Patan Shabaz, Ahireesha B, Rakshitha I, Abhishek A, Harika B","doi":"10.38022/ajhp.v4i2.87","DOIUrl":"https://doi.org/10.38022/ajhp.v4i2.87","url":null,"abstract":"Hypertension has become a significant problem in developing countries which is associated with aging of the population, urbanization, socio economic changes favouring sedentary habits, obesity, alcohol consumption, and salt intake etc. The management of hypertension involves long term treatment & life style modification which will have greater impact on HRQoL. This study aims to give patient counselling regarding risk factors, life style modifications, pharmacological therapy & medication adherence in hypertension which in turn improves HRQoL. \u0000Methodology: Prospective interventional study. The study was conducted in Jayabharath Hospital, located in Nellore district which was conducted for a period of 6 months. Hypertensive patients, of either sex, above 18 years of age, with or without co-morbidities and Patient willing to give there informed consent to participate in the study are included in our study and the Pregnant hypertensive patients are excluded from the study \u0000Results and Discussion: At baseline there was no significance difference between the blood pressures, QoL score, adherence score, and KAP of the test and control groups. As patient in both group continued to see their physician regularly, both showed in improvement in blood pressure control at final follow up. However improvement in the test group blood pressure was more significant reduction (p<0.05).","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"35 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141387781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review paper on anganwadi workers knowledge on maternal nutrition","authors":"Sneha Srivastava, Ritu K. Sureka","doi":"10.38022/ajhp.v3i3.75","DOIUrl":"https://doi.org/10.38022/ajhp.v3i3.75","url":null,"abstract":"The present study reviews the Maternal Nutrition knowledge of health care providers (ANMs and ASHAs) of Primary Health Centers (PHCs) and Community Health Centers (CHCs) and attempts to find out the existing gaps in their knowledge level related to maternal nutrition as well as discusses strategies to bridge those gaps. Good nutrition is the core pillar for human development and its necessity varies with respect to age, gender and during physiological changes such as pregnancy which is a critical phase in a woman's life when the expectant mother needs optimal nutrients to support the developing fetus. Awareness about appropriate nutrition during pregnancy is a serious concern and lack of it may lead to child morbidity and mortality. Therefore it is imperative to address this issue properly in various government policies and schemes. ICDS scheme initiated by Government of India is a major step in this regard which provides nutrition and health education, supplementary nutrition, family planning tips etc. to the pregnant women. The Anganwadi workers are the basic functionaries of the ICDS scheme and their services (providing counseling, supplementary nutrition, distribution of Iron &amp; Folic acid tablets) are transmitted to the beneficiaries through a channel of Anganwadi centers (AWCs). Keeping the above background in mind relevant literature such as journals, newspapers, articles, research papers from Scopus, Pub Med, research gate, and Google scholar related to national and state policies pertinent to maternal nutrition were reviewed to find out the existing gaps in the knowledge level of health care providers. It is concluded from the study that maternal nutritional needs have to be prioritized in government health programmes and strategies to improve the status of expectant mothers need to be implemented to address nutritional challenges. Government schemes can be strengthened by promoting integration of services, ensuring effective procurement mechanisms for supplementary nutrition and food supplements, establishing regional training facilities and strengthening program monitoring and evaluation.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"39 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135514383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subacute Cutaneous Lupus Erythematous","authors":"Mukesh Kumar Saphi, Sunny Kumar Yadav, Bhavya N, Krishnadev Shah, Amit Kumar","doi":"10.38022/ajhp.v3i3.74","DOIUrl":"https://doi.org/10.38022/ajhp.v3i3.74","url":null,"abstract":"Subacute Cutaneous Erythematous (SCLE) is an Auto-Immune skin disorder that cause skin sores and rashes when your immune system attacks itself. In this case report describe 39 years old female patient with SCLE. It is characterized by either ring-shaped red scaly border and also scaly red bumps in sun exposed areas associated with itching, pain and burning sensation. In this case, the patient has a multiple red colour lesions initially on the upper back region then spread to B/L UL, abdomen, chest, face and LL which is aggravating to sunlight. The patient is having a history of skin burns like lesions, tuberculomas and SJS. The diagnosis of SCLE was revealed by clinical presentation, Skin biopsy result and laboratory finding i.e. ANA Test was found to be highly positive and confirms that it is an autoimmune disease. The patient was treated with corticosteroid drug, DMARDs along with antihistaminic drugs and supportive therapy like nutritional supplements and skin lotion for external application, which led to significant improvement in the lesion formation and other symptoms. The case report highlights the careful monitoring and appropriate treatment of SCLE.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135302580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Organic Psychosis Induced by Antitubercular Drugs in A Young Female","authors":"Prakash Nathaniel Kumar Sarella, Janki Pavanilakshmi Dadishetti, Patrick Oliver Asogwa, Ravishankar Kakarparthy","doi":"10.38022/ajhp.v3i2.73","DOIUrl":"https://doi.org/10.38022/ajhp.v3i2.73","url":null,"abstract":"Antitubercular drugs including rifampicin, isoniazid and pyrazinamide can cause rare but severe adverse effects involving the central nervous system. Neuropsychiatric side effects ranging from headache to psychosis have been reported. Early identification and management is crucial to improve outcomes. We report the case of a 26-year-old female with a history of tuberculosis who developed symptoms of organic psychosis after taking antitubercular drugs for 45 days. She presented with altered sensorium, seizures, sensory and memory loss. Diagnosis of drug-induced psychosis was made based on the temporal association and exclusion of other causes. Symptoms resolved after discontinuation of the culprit medications. Clinicians should be aware of neuropsychiatric adverse effects of antitubercular drugs which though rare can be serious. Timely diagnosis and withdrawal of the offending medications are needed to improve outcomes in such cases. \u0000 ","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"45 8 Pt 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125698800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Study: Henoch-Schonlein Purpura in a Geriatric Patient with Gastrointestinal Involvement","authors":"Suberna Basnet, Sanja Na, Vijaya Durga Yalla sai, Tejaswi Allu, Amit Kumar Amit","doi":"10.38022/ajhp.v3i1.72","DOIUrl":"https://doi.org/10.38022/ajhp.v3i1.72","url":null,"abstract":"IgA-mediated immune vasculitis known as Henoch-Schonlein purpura affects the small blood vessels in the joints, kidneys, GI tract, skin, and, less frequently, the brain and lungs. The present case report describes a 62-year-old female patient with Henoch-Schonlein purpura (HSP). HSP is a type of vasculitis that affects small vessels and is characterized by purpura, arthritis, abdominal pain, and kidney involvement. In this case, the patient presented with a rash with red lesions on the upper and lower limbs, crusted lesions on both lower limbs, and acute onset abdominal pain with hematochezia. Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon(fig.1). Biopsies revealed a leukocytoclastic vasculitis in the skin (fig2) and gastrointestinal tract.  The patient had a history of hypertension and smoking, and laboratory investigations revealed leucocytosis, anaemia, and electrolyte imbalances. The diagnosis of HSP was made based on the clinical presentation, laboratory findings, and biopsy results. The patient was treated with a combination of steroids, antibiotics, and supportive care, which led to significant improvement of symptoms and laboratory findings. Steroid therapy was given according to guidelines for the treatment of HSP, and tapering the steroid therapy helped to improve gastrointestinal symptoms. The case report highlights the importance of careful monitoring and appropriate treatment of HSP in geriatric patients, as well as the potential benefits of immunosuppressant therapy.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123544355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case study: interstitial lung disease with pulmonary arterial hypertension and COR Pulmonale","authors":"Sijina Ks, Naga kireeti Seru, Mahima S Mohan, Suberna Basnet, K. Amit","doi":"10.38022/ajhp.v3i1.71","DOIUrl":"https://doi.org/10.38022/ajhp.v3i1.71","url":null,"abstract":"Interstitial lung diseases (ILDs) encompass a diverse group of conditions characterized by inflammation and fibrosis of the lung tissue, which can lead to impaired lungs function and respiratory failure. Pulmonary arterial hypertension (PAH) and cor pulmonale are common complications of ILDs, resulting from increased resistance in pulmonary circulation and right heart strain. ILDs and PAH and cor pulmonale are often difficult to diagnoses as the symptoms can be non-specific and overlap with other respiratory diseases. Diagnostic tool such as pulmonary function tests, imaging studies and right heart catheterization are used to establish a definitive diagnosis and assess to disease severity. This case study summarizes the patient case of ILDs with PAH and cor pulmonale, including the underlying pathophysiology, diagnostic tool and management strategies. Additionally, we discuss the challenges in diagnosing and managing ILDs with PAH and cor pulmonale, as well as potential future direction in research and treatment.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129233324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on monkey pox","authors":"V. V, Pravallika M, M. B, G. V, Ershad Ali S D, V. G","doi":"10.38022/ajhp.v2i4.57","DOIUrl":"https://doi.org/10.38022/ajhp.v2i4.57","url":null,"abstract":"Monkey pox a vesiculo pustular rash illness was initially discover to cause human infection in 1970 through the world health organization (WHO) -sponsered efforts of the commission to certify small pox eradication In western Africa and the congo basin . the virus has been discovered to cause a non human primate rash illness in 1958 and was thus named monkey pox the causative agents of small pox and monkey pox disease both are species of orthopox virus,monkey pox when it effects human as an epizootic produces a similar clinical picture to that of ordinary human smallpox since 1970 extensive epidemiology, virology,ecology, and public health research has enable better characterization of monkey pox virus and the associated human disease .we conducted a sysmatic review of peer-reviewed and grey literacture on how monkey pox epidimology has evolved, with particular  emphasis on the number of confirmed, probable ,  and possible cases,age at presentation and geographical spread. The number of human monkey pox cases has been on the rise since the 1970s ,with the most dramatic increases occurring in the DRC . The median age at presentation has increased from 4 1970s) to 21 years ( 2010-2019).There was an overall case fatality rate of 8.7% with a significant difference between clades -central African  10.6% ( 95% CI: 8.4%-13.3% ) VS WestAfrican 3.6% ( 95% CI:1.7%-6.8% ) .your review shows an escalation of monkey pox cases, especially in the highly endemic DRC , a spread to other  countries, and  a growing median age from young children to young adults . These findings may be related to the cessation of small pox vaccination , which  provided some cross -protection against monkeypox , leading to increased human -to -human transmission. increased  surveillance and detection of monkeypox cases are essential tools for understanding the continousily changing  epidemiology of this resurging disease.   ","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114166970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case study on phenylketonuria: a memic autism","authors":"Nikhila K, Sahithi V, Yaswanth Reddy V, V. G, Manohar Babu Sitty","doi":"10.38022/ajhp.v2i4.54","DOIUrl":"https://doi.org/10.38022/ajhp.v2i4.54","url":null,"abstract":"Phenylketonuria (PKU) is a phenylalanine catabolism metabolic condition characterized by a decrease in the activity of the phenylalanine hydroxylase or Dihydro pteridine reductase enzyme. This inherited condition causes a build-up of phenylalanine in the bloodstream. Elevated phenylalanine levels in the blood can cause muscle rigidity, choreoathetosis, tremors, hyperreflexia, dermatitis, pale skin, and pseudo-scleroderma. The central nervous system deficiencies in PKU are caused by phenylalanine and phenyl pyruvic acid competing for dopamine, adrenaline, norepinephrine, and serotonin in the brain. Structural changes are caused by neurotransmitter inhibition and phenylalanine and phenyl pyruvic accumulations in the white matter of the posterior periventricular, frontal, and subcortical areas of the brain1. Greater myelin turnover decreased synaptogenesis, and reduced neuronal digenesis ensues from myelin deficit, resulting in cognitive development and mental retardation1. The patient in this case study is an 8-year-old boy who has been diagnosed with phenylketonuria. The patient’s parents had a history of consanguinity marriage. The patient has had seizures since he was nine months old. Speech and language delays, hearing loss, and tooth discoloration are all common symptoms. He had an MRI and a brain scan, as well as a blood amino acids test, which revealed that he has mild developmental delays. Mild to Moderate Autistic Features is Delayed.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120962981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug alcohol interactions-a review","authors":"Shyam Kumar Vantaku, Rakesh Boddepalli, Ramakrishna, Keerthana B, Vidyasagar B, Asha Pasala","doi":"10.38022/ajhp.v2i3.53","DOIUrl":"https://doi.org/10.38022/ajhp.v2i3.53","url":null,"abstract":"Chronic Alcoholics can induce interactions with various drugs. Mainly the pharmacokinetic and pharmacodynamics interactions between drugs and alcohol plays an important role. Alcohol can cause potentiallyl harmful effects When people are unaware of known drug interactions, Knowingly combine due to negligence, As a tool to facilitate a crime. Most of the drugs involved are benzodiazepines, cocaine, NSAIDS, metronidazole caution, awareness, and education about the consequences should be enhanced within the alcoholic abusers who are in medication which can cause potential interactions and secondary effects. The elderly and chronic drug abusers are at risk mostly.","PeriodicalId":308084,"journal":{"name":"Asian Journal of Hospital Pharmacy","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127914305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}