Jurnal Insan Farmasi Indonesia最新文献_第2页

PERBANDINGAN HASIL PENETAPAN PARAMETER SPESIFIK DAN NON-SPESIFIK ANTARA SIMPLISIA TERHADAP EKSTRAK METANOL PURUN TIKUS (Eleocharis Dulcis)

Jurnal Insan Farmasi Indonesia Pub Date : 2023-05-31 DOI: 10.36387/jifi.v6i1.1372

Didik Rio Pambudi, Eka Fitri Susiani, Ria Hervina Sari, Noor Rahmah, Cast Torizellia

{"title":"PERBANDINGAN HASIL PENETAPAN PARAMETER SPESIFIK DAN NON-SPESIFIK ANTARA SIMPLISIA TERHADAP EKSTRAK METANOL PURUN TIKUS (Eleocharis Dulcis)","authors":"Didik Rio Pambudi, Eka Fitri Susiani, Ria Hervina Sari, Noor Rahmah, Cast Torizellia","doi":"10.36387/jifi.v6i1.1372","DOIUrl":"https://doi.org/10.36387/jifi.v6i1.1372","url":null,"abstract":"Eleocharis dulcis is a swamp plant has potential as a traditional medicine. The purpose of this study was to compare the results of determining specific and non-specific parameters on simplicia and methanol extract of purun tikus’s stems. Determination of specific parameters includes organoleptic, macroscopic - microscopic tests, water soluble extract content, ethanol soluble extract content and phytochemical screening such as testing for alkaloids, flavonoids, tannins, saponins and steroids/triterpenoids. Determination of non-specific parameters includes drying shrinkage, determination of total ash content, acid insoluble ash content and heavy metal contamination. The results of the study on the specific parameters of stem extract showed that the simplicia powder was light brown in color, had a characteristic odor that was not pungent and had a bitter taste and on microscopic examination only the simplicia could be observed epidermis, transport bundles, parenchyma and collenchyma fragments,. The results of the non-specific simplicia characterization test showed drying shrinkage of 8.91%, total ash content of 13.79%, acid insoluble ash content of 6.89%. The results showed that both simplicia and methanol extract of purun tikus’s stems met the general requirements for specific and non-specific characteristics except for the total ash content of the simplicia which was declared not eligible.","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121758104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFEK SITOTOKSISITAS SENYAWA BIOAKTIF TUMBUHAN TERHADAP SEL KANKER PAYUDARA -SKBR3 CELL LINE : A SYSTEMATIC REVIEW 乳腺癌-SKBR3细胞系的植物活性化合物的细胞毒性:系统回顾

Jurnal Insan Farmasi Indonesia Pub Date : 2023-05-31 DOI: 10.36387/jifi.v6i1.1367

Rita Maliza, Azizah Amatu zikrah, Chairunnisa Azzahra Azzahra H, Hylda Hylda, Aprilia Cassa Nova

引用次数: 0

THE ISOLATION OF α-CELLULOSE & THE PREPARATION OF MICROCRYSTALLINE CELLULOSE FROM SOURSOP LEAVES (Annona muricata L.) 番荔枝叶α-纤维素的分离及微晶纤维素的制备

Jurnal Insan Farmasi Indonesia Pub Date : 2023-05-31 DOI: 10.36387/jifi.v6i1.1298

Y. Lestari, Mi'rajunnisa Mi'rajunnisa, Raudatul Patimah

{"title":"THE ISOLATION OF α-CELLULOSE & THE PREPARATION OF MICROCRYSTALLINE CELLULOSE FROM SOURSOP LEAVES (Annona muricata L.)","authors":"Y. Lestari, Mi'rajunnisa Mi'rajunnisa, Raudatul Patimah","doi":"10.36387/jifi.v6i1.1298","DOIUrl":"https://doi.org/10.36387/jifi.v6i1.1298","url":null,"abstract":"Powder characteristics are very important to consider in the tablet manufacturing process because they can affect the characteristics of the resulting tablets. This study aims to determine the characteristics of microcrystalline cellulose powder isolated from soursop leaves. This research method includes preparation of soursop leaves raw material, isolation of α-cellulose using 17.5% NaOH solution with 3.5% nitric acid (containing 20 mg sodium nitrite), manufacture of microcrystalline cellulose using 1 M HCl solution, and characterization of microcrystalline cellulose including quality checks. powder (organoleptic, identification, solubility), and pH testing. The results showed that the yield of microcrystalline cellulose (MCCDSr) was 96.59% against α-cellulose. The results of the characterization of microcrystalline cellulose powder including organoleptic, identification, solubility, melting point, and pH showed similar characteristics with Avicel® PH 101 as a comparison. Based on the research that has been done, the characteristics of microcrystalline cellulose powder from soursop leaves are similar to Avicel® PH 101.","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123976915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HUBUNGAN SIKLUS MENSTRUASI DENGAN GANGGUAN TIDUR PADA MAHASISWI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS AIRLANGGA ANGKATAN 2019 月经周期与AIRLANGGA大学医学院医学院学生睡眠障碍的关系

Jurnal Insan Farmasi Indonesia Pub Date : 2023-05-31 DOI: 10.36387/jifi.v6i1.1274

Dhawam Decandra Putra, Bambang Purwanto, Jimmy Yanuar Annas

{"title":"HUBUNGAN SIKLUS MENSTRUASI DENGAN GANGGUAN TIDUR PADA MAHASISWI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS AIRLANGGA ANGKATAN 2019","authors":"Dhawam Decandra Putra, Bambang Purwanto, Jimmy Yanuar Annas","doi":"10.36387/jifi.v6i1.1274","DOIUrl":"https://doi.org/10.36387/jifi.v6i1.1274","url":null,"abstract":"Factors that affect the menstrual cycle are hormones, enzymes, vascularization, prostaglandins, psychological factors, chronic disease, malnutrition, physical activity, and drugs. The prevalenceof menstrual cycle abnormalities in Indonesian adolescents is quite high, around 31.6%. Normal sleep disorders in women have risks to health, namely in mood disorders and cognitive function. This study aims to analyze the relationship between menstrual cycle length and sleep disturbances in female medical students. This research is an observational analytic research with cross sectional design. This research was conducted at the Faculty of Medicine, Airlangga University from September 2021 to November 2022. The subjects of this study were 60 female medical students from the Faculty of Medicine, Airlangga University, class of 2019. The independent variable in this study was the menstrual cycle, while the dependent variable in this study was sleep disturbances. Data analysis used in this study was bivariate analysis using fisher's exact test to test the menstrual cycle and sleep disturbances. The conclusion in this study is that there is no relationship between menstrual cycle length and sleep disturbances in female medical students at the Faculty of Medicine, Airlangga University class of 2019 with a value of (p> 0.05)","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128313149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UJI AKTIVITAS ANTELMINTIK EKSTRAK ETANOL KULIT BATANG SENGKUANG Dracontomelon dao (Blume) Merr & Rofle TERHADAP CACING GELANG AYAM (Ascaridia galli) SECARA IN VITRO

Jurnal Insan Farmasi Indonesia Pub Date : 2023-05-31 DOI: 10.36387/jifi.v6i1.1357

Inderiyani Inderiyani, Heny Puspasari, Risma Wahyu Architasari

{"title":"UJI AKTIVITAS ANTELMINTIK EKSTRAK ETANOL KULIT BATANG SENGKUANG Dracontomelon dao (Blume) Merr & Rofle TERHADAP CACING GELANG AYAM (Ascaridia galli) SECARA IN VITRO","authors":"Inderiyani Inderiyani, Heny Puspasari, Risma Wahyu Architasari","doi":"10.36387/jifi.v6i1.1357","DOIUrl":"https://doi.org/10.36387/jifi.v6i1.1357","url":null,"abstract":"Worms are diseases caused by worms that need serious treatment. Sengkuang Dracontomelon dao (Blume) Merr & Rofle has the potential as an alternative worm treatment because it contains secondary metabolites i.e. alkaloids, saponins, tannins, flavonoids and triterpenoids which have activity as anthelmintics. This study aims to determine the activity, LC50 and LT50 values of sengkuang stem bark as an anthelmintic against Ascaridia galli in vitro. Sengkuang bark is processed into simplicia and then macerated using 96% ethanol as a solvent. Then the extract was used to test the anthelmintic activity by incorporating 5 chicken roundworms into each test solution, 0,9% NaCl (negative control), 0,5% mebendazole (positive control), ethanol extract of sengkuang stem bark 0,2%; 0,4%, and 0,6%. Incubated at 37°C and observed the time of paralysis, the time and number of worm deaths every 1 hour for 24 hours. The results showed that the ethanol extract of sengkuang bark at concentrations of 0,2%; 0,4% and 0,6% had anthelmintic activity with a mortality rate of 100%, an LC50 value is 0,13% and an LT50 value respectively is 15,67 hours; 10,83 hours and 7,85 hours.","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130488056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UJI EFEKTIFITAS GEL KOMBINASI EKSTRAK DAUN BELUNTAS (Pluchea indica L. Less) DAN RIMPANG JAHE MERAH (Zingiber officinale Roscoe) TERHADAP BAKTERI Propionibacterium acne DAN Staphilococcus epidermidis 测试鳞茎叶提取物(Pluchea indica L. Less)和红姜根茎(Zingiber officinale Roscoe)对丙乙酰亚丙酮和表皮结膜炎细菌的有效性

Jurnal Insan Farmasi Indonesia Pub Date : 2022-12-31 DOI: 10.36387/jifi.v5i2.946

Mindiya Fatmi, A. E. Wibowo, D. Rahmat

{"title":"UJI EFEKTIFITAS GEL KOMBINASI EKSTRAK DAUN BELUNTAS (Pluchea indica L. Less) DAN RIMPANG JAHE MERAH (Zingiber officinale Roscoe) TERHADAP BAKTERI Propionibacterium acne DAN Staphilococcus epidermidis","authors":"Mindiya Fatmi, A. E. Wibowo, D. Rahmat","doi":"10.36387/jifi.v5i2.946","DOIUrl":"https://doi.org/10.36387/jifi.v5i2.946","url":null,"abstract":"Beluntas leaf (Pluchea indica L. Less) and red ginger rhizome (Zingiber officinale Roscoe) is a plan have activity as antibacterial causes acne. Beluntas leaf contain antibacterial compounds from alkaloid, flavonoid free type flavonol, steroid and tannin. Red ginger rhizome extract compounds flavonoid, essential oil, polifenol, and saponin. This study aim to develop gel product extract combination from beluntas extract and red ginger rhizome at concentration 1: 1; 1: 2 and 3:2 formulated in gel, then tested the physical characteristic and gel microbiology tested on P. acne and S. epidermidis. Beluntas leaf and red ginger rhizome extracted by maceration in ethanol 96%, and carbopol 934 as gel base. Physical characteristic test comprise homogeneity, organoleptic, pH, dispersion gel and viscosity. Microbiology tested use method diameter of inhibition zone with Medi-Klin Gel® as positive control. The result show homogeneous gel preparation, with brownish green color, ginger smell, pH 5,83-6,07, spreadability 5,1-5,7 cm, viscosity 690000 cp-1460800 cp. effect of adding extract beluntas leaf and red ginger rhizome to gel preparation, in both single and combination extracts. Antibacterial evaluation showed that formula 3 give the best effectiveness with 5,92 mm zone of inhibition against P. acnes and 4,15 mm against S. epidermidis","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125276243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUASI DRUG RELATED PROBLEMS PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI FARMASI RAWAT INAP RUMAH SAKIT TK.III DR. R. SOEHARSONO 评估TK医院药物药物使用2型糖尿病患者的药物相关问题。我是索尔哈索诺医生

Jurnal Insan Farmasi Indonesia Pub Date : 2022-12-31 DOI: 10.36387/jifi.v5i2.920

Nazhipah Isnani, Muliyani Muliyani, Muhammad Zaini, Putri Sheila Wardhani

{"title":"EVALUASI DRUG RELATED PROBLEMS PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI FARMASI RAWAT INAP RUMAH SAKIT TK.III DR. R. SOEHARSONO","authors":"Nazhipah Isnani, Muliyani Muliyani, Muhammad Zaini, Putri Sheila Wardhani","doi":"10.36387/jifi.v5i2.920","DOIUrl":"https://doi.org/10.36387/jifi.v5i2.920","url":null,"abstract":"Diabetes mellitus is a disease characterized by hyperglycemia and disturbances of carbohydrate, fat and protein metabolism associated with absolute or relative deficiency of insulin action and/or secretion. The purpose of this study was to determine the characteristics of type 2 DM patients and whether there were DRPs (Drug Related Problems) using antidiabetic drugs in patients with Type 2 Diabetes Mellitus at the Inpatient Pharmacy Installation of Tk.III Hospital Dr. R. Soeharsono period 2019-2020. This research is a non-experimental research with a descriptive research design with a retrospective approach. The sampling technique used was total sampling with a sample of 42 patients taken from the medical records of type 2 DM patients who received antidiabetic drugs at the Inpatient Pharmacy Installation of Tk.III Hospital Dr. R. Soeharsono Banjarmasin. From the results of this study, type 2 diabetes was mostly experienced by women, 25 patients (60%) with an age range of 41-60 years (62%), with the most diabetes complications being hypertension (59.5%). There were 22 patients (52.3%) who experienced DRPs by category in a row, namely drug interactions (33.3%), drugs without indications (14%), indications without drugs (4 ,7%), wrong drug (2.4%), under dose (4.7%), and over dose (0%).","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"619 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131508567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PENGARUH SUHU PENYEDUHAN TERHADAP EFEK DIURETIK TEH HIJAU PADA MENCIT JANTAN GALUR SWISS 高温影响绿茶利尿剂对瑞士格栅的影响

Jurnal Insan Farmasi Indonesia Pub Date : 2022-12-31 DOI: 10.36387/jifi.v5i2.1148

Agustina Susilowati, Nur Karim Kusuma Ramadhan

{"title":"PENGARUH SUHU PENYEDUHAN TERHADAP EFEK DIURETIK TEH HIJAU PADA MENCIT JANTAN GALUR SWISS","authors":"Agustina Susilowati, Nur Karim Kusuma Ramadhan","doi":"10.36387/jifi.v5i2.1148","DOIUrl":"https://doi.org/10.36387/jifi.v5i2.1148","url":null,"abstract":"Tea (Camelia sinensis L.) is a beverage that is familiar to the community and is drunk by brewing it. Green tea contains chemicals such as polyphenols, tannins, steroids and flavonoids. This study aimed to determine the effect of temperature brewing of green tea in the diuretic effect of male swiss strain mice. This research is an experimental study with 25 mice which were divided into five groups, group I (CMC Na 1%), Group II (Furosemide dose 5.2 mg/KgBB), Group III,IV and V (green tea brewed at 50oC,70oC dan 90oC ) with a brewing time of 5- 15 minutes. Urine measurements were performed every 1 hour for 6 hours. Data analysis was carried out using the One-Way ANOVA test followed by the LSD test with a 95% confidence level. The results showed that the diuretic effect at a brewing temperature of 50oC was not significantly different (p> 0.05) with the diuretic effect at 70oC but the average volume of urine at 50oC was greater than 70oC. Diuretic effect at temperature 90oC was significantly different (p<0.05) compared to 50oC and 70oC. The diuretic effect of green tea can be optimal, if the brewed at a temperature of 50oC and 70oC for 5-15 minutes","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"249 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121213977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UJI STABILITAS FISIK SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN KENITU (Chrysophyllum cainito L.) 检测剂型凝胶从KENITU叶子乙醇提取物(Chrysophyllum cainito L)中提取的生理稳定性。

Jurnal Insan Farmasi Indonesia Pub Date : 2022-12-31 DOI: 10.36387/jifi.v5i2.1064

Gina Septiani Agustien, Nitya Nurul Fadilah, Dina Fitri Nusyifa

引用次数: 1

PERBEDAAN PENURUNAN TEKANAN DARAH PASIEN HIPERTENSI YANG DIBERIKAN TERAPI AMLODIPIN PADA PAGI HARI DAN MALAM HARI DI PUSKESMAS BAYANAN KABUPATEN HULU SUNGAI SELATAN 高血压患者的血压在上午和晚上在普斯马斯南部选区进行的淀粉样疗法之间的差异下降

Jurnal Insan Farmasi Indonesia Pub Date : 2022-12-31 DOI: 10.36387/jifi.v5i2.1012

Khalisah Khalisah, Nurul Mardiati, Lisa Setia, Saidillah Saidillah

{"title":"PERBEDAAN PENURUNAN TEKANAN DARAH PASIEN HIPERTENSI YANG DIBERIKAN TERAPI AMLODIPIN PADA PAGI HARI DAN MALAM HARI DI PUSKESMAS BAYANAN KABUPATEN HULU SUNGAI SELATAN","authors":"Khalisah Khalisah, Nurul Mardiati, Lisa Setia, Saidillah Saidillah","doi":"10.36387/jifi.v5i2.1012","DOIUrl":"https://doi.org/10.36387/jifi.v5i2.1012","url":null,"abstract":"Research on timing taking amlodipine drugs against decrease in blood pressure showed different results, that’s significant and insignificant effect. Research to identify differences in blood pressure reduction from hypertension patients given amlodipine drug therapy in the morning with night at Puskesmas Bayanan Hulu Sungai Selatan Regency. This research method is obsevasional descriptive with Pre and post test design. There are two groups this design, namely hypertension patients given amlodipine drug therapy in the morning and night, blood pressure measured before and after 10 days of observation, then compared between difference in the decrease in blood pressure of patients given amlodipine drug therapy in the morning and night. The results of respondents given amlodipine drug therapy in the morning experienced average decrease in blood for systole -13.67 mmHg and for diastole -6.33 mmHg. Meanwhile, those given amlodipine therapy at night experienced average decrease in blood for cystole -19 mmHg and for diastole -10.33 mmHg. Wilcoxon sigh test results for blood pressure systole values Asymp.sig. 0.007 and for diastole blood pressure values Asymp.sig. 0.003 or <0.05 which states hypothesis is accepted or there is difference between decrease in blood pressure of hypertension patients given amlodipine drug therapy in the morning and night.","PeriodicalId":306551,"journal":{"name":"Jurnal Insan Farmasi Indonesia","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126784417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0