检测剂型凝胶从KENITU叶子乙醇提取物(Chrysophyllum cainito L)中提取的生理稳定性。

Gina Septiani Agustien, Nitya Nurul Fadilah, Dina Fitri Nusyifa
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引用次数: 1

摘要

Kenitu叶含有抗氧化剂黄酮类化合物,可以抵消自由基的不良影响,如果外用剂型配制,抗氧化效果会更好。用于面部的外用剂型之一是可剥离的凝胶面膜,它的使用很容易像弹性膜一样去除。本研究的目的是确定剥脱式凝胶膜制剂的物理稳定性。采用实验方法,根据提取物浓度的变化,分别配制F1(2%)、F2(4%)和F3(8%)三种剥脱式凝胶面膜配方。对制剂的物理稳定性进行评价,包括感官观察、均匀性、pH、粘附性、分散性、制剂干燥时间和粘度。结果表明,可剥凝胶掩膜制剂的物理稳定性试验可采用可剥凝胶掩膜制剂的形式进行,最佳掩膜配方为F1,提取物浓度为2%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
UJI STABILITAS FISIK SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN KENITU (Chrysophyllum cainito L.)
Kenitu leaves contain flavonoids which function as antioxidants that can counteract the bad effects of free radicals, the antioxidant effect will be better if formulated in topical dosage forms. One of the topical dosage forms for use on the face is a peel-off gel mask, its use is easy to remove like an elastic membrane. This study aims to determine the physical stability of the peel-off gel mask preparation of kenitu leaves ethanol extract. The research method was experimental by making three peel-off gel mask formulations based on variations in extract concentration, namely F1 (2%), F2 (4%) and F3 (8%). Evaluations were carried out on the physical stability of the preparation, including organoleptic observations, homogeneity, pH, adhesion, dispersibility, drying time of the preparation, and viscosity. The results showed that the physical stability test of the peel-off gel mask preparation of kenitu leaves ethanol extract could be formulated in the form of a peel-off gel mask preparation, and the best mask formula was F1 with an extract concentration of 2%.
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