International Journal of Integrated Health Sciences最新文献_第7页

Clinical Neurogenetics of Syndrome Z and Scientific Evidence-Based Clinical Evaluation Z证临床神经遗传学及科学循证临床评价

International Journal of Integrated Health Sciences Pub Date : 2022-03-30 DOI: 10.51219/jih/furlanetto-m-l-jr/5

Furlanetto M L

引用次数: 0

Correlation between serum KL-6 level and severity of SARD-related ILD 血清KL-6水平与sard相关ILD严重程度的相关性

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2652

E. Pranggono, Alvy Syukrie, Valentine Moenadri, S. Dewi

{"title":"Correlation between serum KL-6 level and severity of SARD-related ILD","authors":"E. Pranggono, Alvy Syukrie, Valentine Moenadri, S. Dewi","doi":"10.15850/ijihs.v10n1.2652","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2652","url":null,"abstract":"Objective: To understand the correlation between serum KL-6 level and severity of SARD-related ILD in Indonesia. Method: This was a cross-sectional study to evaluate the correlation between serum KL-6 level and Interstitial Lung Disease (ILD) severity based on Chest High-Resolution Computed Tomography (Chest HCRT) among patients with Systemic Autoimmune Rheumatic Disorders (SARD) who visited the Rheumatology Clinic of Dr. Hasan Sadikin General Hospital during the period of January 2019 to February 2020. Secondary data were retrieved from a study on the Effects of Ciplukan Herbs on Organ Fibrosis. KL-6 serum concentration was measured from stored biological material and the correlation between the serum KL-6 level and ILD severity was analyzed by Rank Spearman's test. Results: Thirty-four patients participated in this study with a median age of 37 years-old. Most of the participants were female (94.1%), Sundanese (64.7%), and had systemic sclerosis as an underlying disease (48.5). The median serum KL-6 level was 57.1 U/ml (21.6-444.1). Most participants belonged to severe ILD group (58.8%) with a mean serum KL-6 level of 65.1±48.9 U/ml. The highest mean serum KL-6 level (111.6±121.8) was observed in the moderate ILD group comprising of 32.4% of the participants. The remaining 11.8% participants belonged to mild ILD group with a mean serum KL-6 level of 61.1±24.9 U/ml. Serum KL-6 level was demonstrated to have a weak correlation with ILD severity (r=-0.229, p=0.193). Conclusion. There is an insignificant weak correlation between serum KL-6 level and ILD severity based on chest HRCT in SARD patients.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45117425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal Parameters in Mild, Moderate, and Chronic Cigarette Smokers 轻度、中度和慢性吸烟者的肾脏参数

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2558

Dinesh Kumar, Preeti Sharma, Sudeep Kumar, Sumesh Prasad Sah, Manisha Arora, S. Iqbal, Pradeep Kumar

{"title":"Renal Parameters in Mild, Moderate, and Chronic Cigarette Smokers","authors":"Dinesh Kumar, Preeti Sharma, Sudeep Kumar, Sumesh Prasad Sah, Manisha Arora, S. Iqbal, Pradeep Kumar","doi":"10.15850/ijihs.v10n1.2558","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2558","url":null,"abstract":"Objective: To explore the link between cigarette smoking and kidney function through renal parameter assessment. Methods: The present study was performed at the Department of Biochemistry Santosh Medical College, Ghaziabad, India, from September 2019 to April 2021. In this study, 140 subjects were included, out of which 35 were non-smokers, 35 smoked <5 cigarette per day, 35 smoked 5-10 cigarette per day, and the remaining 35 smoked more than 10 cigarettes per day. Results: Blood urea, serum creatinine, urinary albumin, and uACR levels were found to increase significantly (p<0.001) in smokers as compared to non-smokers. These increases were higher among chronic cigarette smokers (p<0.001) as opposed to mild and moderate smokers. In contrast, serum uric acid, e-GFR, and urinary creatinine levels decreased significantly (p<0.001) in smokers when compared to non-smokers, with a higher decrease observed in chronic cigarette smokers (p<0.001) as opposed to the mild and moderate cigarette smokers. Conclusion: Alterations in urinary albumin, serum urea, serum creatinine, urinary creatinine, and e-GFR are associated with the risk of renal dysfunction.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42844923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paraoxonase 1 Activities and Lipid Parameters in Hypertension and Their Association with Chronic Alcoholism 高血压患者对氧磷酶1活性和脂质参数及其与慢性酒精中毒的关系

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2595

Sudeep Kumar, J. Batra, Sumesh Prasad Sah, D. Kumar, S. Iqbal, Manisha Arora, Shivani Sharma

{"title":"Paraoxonase 1 Activities and Lipid Parameters in Hypertension and Their Association with Chronic Alcoholism","authors":"Sudeep Kumar, J. Batra, Sumesh Prasad Sah, D. Kumar, S. Iqbal, Manisha Arora, Shivani Sharma","doi":"10.15850/ijihs.v10n1.2595","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2595","url":null,"abstract":"Objective: To determine lipid profile, antioxidant vitamin (E and C), and malondialdehyde (MDA) levels, as well as superoxide dismutase (SOD) levels and paraoxonase 1 (PON 1) activities in alcoholic hypertensive patients. Methods: Five hundred subjects were selected for this study consisting of 250 normal healthy individuals and 250 alcoholic hypertensive subjects. Total cholesterol, triglyceride, and HDL levels were measured using the enzymatic method while the LDL and VLDL levels were calculated by Friedwald equation. The MDA level were measured using thiobarbiturate (TBA) and the Vitamin E and C were measured using the enzymatic method. The SOD and PON 1 activities were measured using phenyl acetate as the substrate. Results: Total cholesterol, triglycerides, LDL, VLDL, and MDA levels were found to be significantly high while the HDL and Vitamin E and C levels decreased among the alcoholic hypertensive subjects when compared to the control. Furthermore, significant decreases in SOD and PON 1 activities were also found among the alcoholic hypertensive subjects as compared to control. Conclusion: Alterations in lipid parameters, antioxidant vitamin levels, MDA level, SOD activities, and PON 1 activities are associated with hypertension that may be enhanced by alcohol intake, which may lead to the development cardiovascular disease.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42206045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unexpected Infective Endocarditis in Corrected Congenital Heart Disease: A Case Report 先天性心脏病矫正后意外感染性心内膜炎1例报告

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2166

C. J. Cool, Rachmi Serulina, Aninka Saboe

{"title":"Unexpected Infective Endocarditis in Corrected Congenital Heart Disease: A Case Report","authors":"C. J. Cool, Rachmi Serulina, Aninka Saboe","doi":"10.15850/ijihs.v10n1.2166","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2166","url":null,"abstract":"Objective: To describe patients with corrected Congenital Heart Disease (CHD) who experienced Infective Endocarditis (IE). Methods: Two cases of IE were observed in 2019. The first case involved a 36-year-old woman with previous percutaneous transcatheter perimembranous ventricular septal defect (VSD) closure four months before admission. Echocardiography showed vegetation at noncoronary cusps of the aortic valve. Patient received antibiotics for six weeks and underwent surgery for evacuation of vegetation and device, along with VSD closure with a cardiovascular patch (Gore-tex). The second case involved a 43-year-old woman with a history of surgical closure in secundum atrial septal defect (ASD) by pericardial patch two months before admission. Echocardiography showed vegetation at the tricuspid valve. Patient received antibiotics for four weeks and planned for surgery to evacuate vegetation. Results: IE is one of the major complications in CHD, whether uncorrected, treated, or corrected. The risk of IE increased with an invasive procedure. Post closure IE is rare. Poor dental hygiene and immunocompromised also increased patient's risk to be exposed to IE as shown in the first patient who had dental caries and the second patient who was on methylprednisolone for post-surgical pericardial effusion treatment. Conclusion: The risk of IE increases with invasive procedures in CHD patients. Although the incidence of IE is quite rare, its possibility should become of a serious concern among physicians.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48708607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential Diagnosis of Fever of Unknown Origin in Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) 药物反应不明发热伴嗜酸性粒细胞增多症和系统症状的鉴别诊断

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2198

Kevin Fachri Muhammad, Ferdy Ferdian, A. Rahmadi

{"title":"Differential Diagnosis of Fever of Unknown Origin in Drug Reaction with Eosinophilia and Systemic Symptom (DRESS)","authors":"Kevin Fachri Muhammad, Ferdy Ferdian, A. Rahmadi","doi":"10.15850/ijihs.v10n1.2198","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2198","url":null,"abstract":"Objective: To describe an unusual case of drug reaction with eosinophilia and systemic symptoms presenting as fever of unknown origin (FUO) and the diagnostic hurdles that come with the presence of differential diagnosis of FUO, which is tuberculous lymphadenitis. Methods: A 34-year-old female with a chief complaint of fever that has lasted for 3 weeks accompanied with jaundice and skin rashes for 2 weeks was admitted with an indication of FUO. She had a history of carbamazepine consumption for trigerminal neuralgia 2 months prior. Cervical lymphadenopathy was palpable bilaterally and hepatomegaly, elevated liver enzyme, as well as hyperbilirubinemia were observed. After excluding differentials for many causes of prolonged fever, patient was treated for Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) and was given intravenous steroid injections. Fine needle aspiration biopsy was performed for her cervical lymphadenopathy. Results: Biopsy presented a mix of sialadenitis and tuberculous lymphadenopathy. Clinical improvement was observed on the second day after steroid administration. Patient was discharged on the seventh day after steroid administration. Conclusion: FUO is one of the possible manifestations of DRESS; however, thorough investigation still needed to be done considering the possibility of more than one entity of disease that can cause FUO in patients, such as tuberculous lymphadenopathy seen in this case.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42202339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary Chronic Immune Thrombocytopenia in Diffuse Large B-cell Lymphoma: A Rare Case Report 弥漫性大B细胞淋巴瘤继发性慢性免疫性血小板减少：一例罕见病例报告

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2603

Putri Vidyaniati, Fransisca, K. Rizki, A. Oehadian

{"title":"Secondary Chronic Immune Thrombocytopenia in Diffuse Large B-cell Lymphoma: A Rare Case Report","authors":"Putri Vidyaniati, Fransisca, K. Rizki, A. Oehadian","doi":"10.15850/ijihs.v10n1.2603","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2603","url":null,"abstract":"Objective: To present a case of rare secondary chronic immune thrombocytopenia in diffuse large B-cell lymphoma. Methods: A case of secondary ITP associated with diffuse large B-cell lymphoma (DLBCL) in a 58-year-old woman suffering from hemorrhagic tendencies that was refractory to conventional treatments of ITP was reported. This case is a rarity because there are not many cases of secondary chronic ITP due to DLBCL have been reported to date. Results: A 58-year-old woman was diagnosed with ITP around 11 months before she was admitted to the Emergency Room with bleeding. Previous treatment with steroid and azathioprine was only temporarily effective. During the course of treatment, splenomegaly and lymphadenopathy were identified, but lymph node biopsy was delayed by the thrombocytopenia. The drug was then replaced to the eltrombopag, which showed good response. However, the patient had to undergo splenectomy because of the mechanical effect of splenomegaly, with the biopsy result showed DLBCL. Immune thrombocytopenia then went into a complete remission after splenectomy. Conclusion: In cases of ITP that are refractory to conventional treatments, a thorough search for secondary ITP might be helpful, even if no underlying disorder is detected at the initial presentation.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42905996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indications and Complications of Orthopedic Hardware Removal in an Indonesian Tertiary Hospital: A Descriptive Study 印度尼西亚一家三级医院骨科硬体取出的适应症和并发症:一项描述性研究

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2695

Shadrina Affifa Azzahra, R. Primadhi, Titing Nurhayati, Muhammad Naseh Sajadi, A. Achadiyani

{"title":"Indications and Complications of Orthopedic Hardware Removal in an Indonesian Tertiary Hospital: A Descriptive Study","authors":"Shadrina Affifa Azzahra, R. Primadhi, Titing Nurhayati, Muhammad Naseh Sajadi, A. Achadiyani","doi":"10.15850/ijihs.v10n1.2695","DOIUrl":"https://doi.org/10.15850/ijihs.v10n1.2695","url":null,"abstract":"Objective: To acquire clinical data regarding indications of implant removal and complications in orthopedic metal implant removal. Methods: This was a cross-sectional observational descriptive study using patient medical records. The inclusion criterion was all patients who underwent orthopedic metal implant removal during 2018-2020 while the exclusion criterion was unintentional implant removal due to subsequent injury or loosening. Data regarding anatomic regions, indications, and complications were collected and presented in tables. Results: In 112 patients participated in this study consisting of 75 (67%) men and 37 (33%) women, the implants were mainly located in thigh, lower leg, and ankle (53% combined). The most common indication for metal implant removal was conversion (31%), followed by infection (25%) and patient's request (20%). The only complication observed in orthopedic metal implant removal in this study was disturbed wound healing in a small percentage of the patients (16%). Most patients (84%) did not experience any complication due to metal implant removal. Conclusions: Indications for metal implant removal may vary, with or without symptoms. Disturbed wound healing is a complication observed in metal implant removal. Despite the advantages of removal, further analysis and guidelines are needed to avoid unnecessary hardware removal considering the risk of complications.","PeriodicalId":30637,"journal":{"name":"International Journal of Integrated Health Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47279325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Depression, Anxiety, and Stress due to Changes in Employment Status during COVID-19 Pandemic: A Study in Badung Districts, Bali, Indonesia COVID-19大流行期间就业状况变化导致的抑郁、焦虑和压力:印度尼西亚巴厘巴东地区的一项研究

International Journal of Integrated Health Sciences Pub Date : 2022-03-01 DOI: 10.15850/ijihs.v10n1.2541

M. Yani, Made Sindy Astri Pratiwi, Agus Indra Yudhistira Diva Putra, N. K. S. Diniari

引用次数: 1

Novel Insights into the Concepts of Masurika in Madhava Nidana 《中观禅学》中Masurika概念的新见解

International Journal of Integrated Health Sciences Pub Date : 2022-01-01 DOI: 10.4103/jihs.jihs_15_22

Kshama Gupta, Prasad Mamidi

引用次数: 0