Cellular, Molecular and Biomedical Reports最新文献_第7页

Pregnancy-induced hypertension: risk factors and current treatment strategies 妊娠高血压:危险因素和当前治疗策略

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.387076.1111

C. Kumar, Sayon Roy, T. Aishwarya, Chilkuri Shashank Setty, Omamah Afreen, Ammapally Maheshwari, Hafsa Ansari

{"title":"Pregnancy-induced hypertension: risk factors and current treatment strategies","authors":"C. Kumar, Sayon Roy, T. Aishwarya, Chilkuri Shashank Setty, Omamah Afreen, Ammapally Maheshwari, Hafsa Ansari","doi":"10.55705/cmbr.2023.387076.1111","DOIUrl":"https://doi.org/10.55705/cmbr.2023.387076.1111","url":null,"abstract":"Hypertensive disorders during pregnancy are a major public health concern in both developed and developing countries. Early detection and treatment of maternal health issues reduce the severity of these issues. This study set out to identify possible risk factors of these conditions and evaluate current methods of treatment. Throughout the research (6 months), 80 PIH women who met the inclusion criteria were studied in an observational study. Women in their twenties and thirties are more likely to have pregnancy-induced hypertension. Preeclampsia and gestational hypertension in pregnancy are the most common types. Hypertension issues are more common among pregnant women who are more likely to be obese, have had previous pregnancies, and reside in rural areas. Medication for the treatment of pregnancyinduced hypertension is prescribed and administered regarding drugs used for primary hypertension. Methyldopa and labetalol are examples of first-line treatments. Patients with PIH who are about to give birth are given hydralazine intravenously (IV) or nifedipine orally (P.O.) as a second-line treatment. When providing antihypertensive medicines or any other medications, the wellbeing of both maternal and fetal is taken into consideration. The risks to both mother and child may be reduced with prompt treatment with additional, safe medications. Article info Received: 14 Jan 2023 Revised: 06 Mar 2023 Accepted: 12 Apr 2023 Use your device to scan and read the article online","PeriodicalId":304796,"journal":{"name":"Cellular, Molecular and Biomedical Reports","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129351554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Research progress on therapeutic effect and mechanism of hydrocortisone on sepsis 氢化可的松治疗败血症的疗效及机制研究进展

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.377524.1090

Yicen Long, Xiaoqiang Du, Zhi Ouyang, Jian Zhong, Y. Zeng

引用次数: 6

COVID-19 and Brain complications in adult and pediatric patients: A review on neuroimaging findings COVID-19与成人和儿童患者脑并发症:神经影像学研究综述

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.380339.1094

Farhad Nalaini, Saleh Salehi Zahabi, M. Abdoli, E. Kazemi, M. Mehrbakhsh, S. Khaledian, Reza Fatahian

引用次数: 0

The comparison of umbilical cord artery pH in newborns with and without thick meconium stained amniotic fluid 新生儿脐带动脉pH值在有和没有厚胎粪染色羊水的比较

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.388391.1112

Nooshin Amjadi, M. Talayeh, Mohadese Momeni, N. Mansouri

{"title":"The comparison of umbilical cord artery pH in newborns with and without thick meconium stained amniotic fluid","authors":"Nooshin Amjadi, M. Talayeh, Mohadese Momeni, N. Mansouri","doi":"10.55705/cmbr.2023.388391.1112","DOIUrl":"https://doi.org/10.55705/cmbr.2023.388391.1112","url":null,"abstract":"Meconium-stained amniotic fluid (MSAF) affects 15-20% of term pregnancies. Recent studies have shown that MSAF has adverse effects on neonatal outcomes. There is no scientific consensus on the incidence of fetal distress in MSAF neonates, and most cesarean sections due to MSAF are unnecessary. The present study was conducted to assess umbilical artery blood pH in neonates with MSAF and to examine whether there is a relationship between MSAF and fetal distress. A clinical survey case-control was conducted on the neonates of 200 pregnant women admitted to a delivery unit of the obstetrics and Gynecology center in Amir al-Momenin Hospital, Zabol in 2014. Neonates born with MSAF made up the case group, and the control group consisted of neonates born with clear amniotic fluid. Umbilical cord arterial pH, gestational age, gender, mode of delivery, and one and five-minute Apgar scores were considered in both groups. The mean pH of the umbilical cord artery blood in the infants of the case group was 7.25, and the mean pH of the umbilical cord artery in the infants of the control group was 7.29 (P = 0.93). The mean gestational age in the case and control groups was 40.08 weeks and 38.32 weeks, respectively (P= 0.03). In this study, a cesarean delivery (P=0.001) and female gender (P= 0.016) were higher in the case group than in the control group. MSAF does not necessarily imply fetal distress, so urgent cesarean sections are unnecessary. This study showed that based on the acidity variables of the umbilical cord artery, there is no statistically significant correlation between the Apgar score at the 1st and 5th minute. While a significant difference has been observed between the type of delivery, gestational age and baby's gender.","PeriodicalId":304796,"journal":{"name":"Cellular, Molecular and Biomedical Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121386430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The effect of premenstrual tension on academic performance and social interactions among Iraqi medical students 经前紧张对伊拉克医学生学习成绩和社会交往的影响

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.390101.1113

Israa Talib Hassan, Hala Saadi Issa, Ekhlas M. Hussein, Reem Ali Haddad

{"title":"The effect of premenstrual tension on academic performance and social interactions among Iraqi medical students","authors":"Israa Talib Hassan, Hala Saadi Issa, Ekhlas M. Hussein, Reem Ali Haddad","doi":"10.55705/cmbr.2023.390101.1113","DOIUrl":"https://doi.org/10.55705/cmbr.2023.390101.1113","url":null,"abstract":"Premenstrual tension is a common public health problem that significantly affects the personal well-being, academics, and of adolescents’ life quality. Consequently, the purpose of the study is to ascertain the prevalence of premenstrual tensions and evaluate its academic and social impact on Iraqi female medical students. From February 2022 to May 2022, a cross-sectional study was carried out at several institutions in Baghdad/Iraq, including (the College of Medicine, Pharmacy, and Dentistry). An online self-questionnaire was used to gather information on the premenstrual tension symptoms, menstrual pain, and academic performance of 2080 Iraqi female medical students. Most respondents (73.6%) experienced various premenstrual symptoms with varying degrees of severity; the most frequent symptoms were depressed mood, anger, irritability, flatulence, acne, and breast tenderness. Approximately (49.0%) of the participants experienced menstrual pain, (78.1%) reported regular menstruation, and (40%) reported learning difficulties. The predominant impact on academic performance was lack of concentration (39.5%) and difficulty in work (34.0%). Among the participants, the majority of the students (59.4%) reported self-medicating with painkillers such as NSAIDs. Furthermore, the study shows that premenstrual symptoms were significantly linked with reduced academic performance and interpersonal relationships among Iraqi medical students (P<0.001). The current study found that premenstrual tension symptoms are associated with poor educational performance and poor interpersonal relationships among Iraqi female medical students. To close the gender gap in our society for a better future, more study is required to analyze and assess the cause of premenstrual tension symptoms and therapeutic interventions.","PeriodicalId":304796,"journal":{"name":"Cellular, Molecular and Biomedical Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129760311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The progress and development trends on stress granules in the world and China during the past 35 years 近35年来国内外应力颗粒研究进展及发展趋势

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.400513.1155

Wenyuan Li, Yao Wang

{"title":"The progress and development trends on stress granules in the world and China during the past 35 years","authors":"Wenyuan Li, Yao Wang","doi":"10.55705/cmbr.2023.400513.1155","DOIUrl":"https://doi.org/10.55705/cmbr.2023.400513.1155","url":null,"abstract":"Stress granules (SGs) will be produced when the body is under external stimuli, and SGs play an important role in the pathogenesis of more and more diseases. The study on SGs has generally grown to a comprehensive subject in the past 35 years (from 1988 to 2022). The bibliometric analysis was used to comprehensively analyze the progress and development trend of SGs research. The literature output in the field of peritoneal dialysis showed a fluctuating growth in the past 35 years, and the last five years were the peak period of literature output. Journal of virology was the most widely published journal on SGs. And the most common research category was Biochemistry Molecular Biology. No matter in terms of the number of papers, citation frequency, H-index, or the distribution of journals and funding sources, the United States was far away from leading. With the enhancement of economic and scientific research strength, China has gradually carried out research on SGs. However, the citation frequency and H-index of Chinese papers were relatively low. Research cooperation between research institutions was relatively close, but domestic research institutions had less cooperation with relevant international institutions. The cooperation among authors was relatively scattered, and further exchanges and cooperation between scholars were needed for Chinese scholars. There are more and more reports about SGs, but there was still a big gap between China and the United States in the study of SGs. Article info Received: 02 Feb 2023 Revised: 28 Apr 2023 Accepted: 17 Jul 2023 Use your device to scan and read the article online","PeriodicalId":304796,"journal":{"name":"Cellular, Molecular and Biomedical Reports","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127612894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-translational modifications of proteins in tumor immunotherapy and their potential as immunotherapeutic targets 肿瘤免疫治疗中蛋白质的翻译后修饰及其作为免疫治疗靶点的潜力

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.378480.1091

Yang Yang, Yuxue Jiao, M. Mohammadi

{"title":"Post-translational modifications of proteins in tumor immunotherapy and their potential as immunotherapeutic targets","authors":"Yang Yang, Yuxue Jiao, M. Mohammadi","doi":"10.55705/cmbr.2023.378480.1091","DOIUrl":"https://doi.org/10.55705/cmbr.2023.378480.1091","url":null,"abstract":"Protein is an important component of life. Protein modification after translation enriches the diversity of protein, regulates the structure and function of a protein, and participates in more life processes. Recent studies have found that post-translational modifications of proteins can regulate the occurrence and development of tumors. The human immune system should be able to eliminate cancer cells through an acquired immune response executed by T cells. However, clinical detection of cancer cells often results from the failure of immune surveillance. Therefore, relieving immune suppression and restoring antitumor immune response provides the possibility for tumor therapy. Tumor immunotherapy refers to exogenous intervention of the body's immune system, restart and maintain the \"tumor-immune\" cycle, restore and improve the anti-immune response of the group, strengthen the recognition and killing ability of tumor cells, so as to achieve the therapeutic effect of controlling or even clarifying the tumor specifically. Here, we review current knowledge of the current status of tumor immunotherapy and the types and effects of post-translational modifications of proteins, hoping to improve new ideas for the types of therapies","PeriodicalId":304796,"journal":{"name":"Cellular, Molecular and Biomedical Reports","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122382471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Investigation of GJB2 and SLC26A4 genes related to pendred syndrome genetic deafness patients GJB2和SLC26A4基因与悬垂综合征遗传性耳聋相关的研究

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.379262.1093

H. M. Al-Zaidi, F. Mousavinasab, Nika Radseresht, Ali Reza Mirzaei, Y. Moradi, Mohammad Mahmoudifar

引用次数: 1

A study on uterine fibroids effective treatment and associated risks factors in the tertiary care teaching hospital 三级教学医院子宫肌瘤有效治疗及相关危险因素的研究

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.384489.1096

引用次数: 2

Performance and accuracy of SD Bioline malaria Ag P.f (05fk50) in relation to microscopy as the gold standard technique for malaria diagnosis SD Bioline malaria Ag P.f (05fk50)与显微镜作为疟疾诊断金标准技术的性能和准确性

Cellular, Molecular and Biomedical Reports Pub Date : 1900-01-01 DOI: 10.55705/cmbr.2023.376615.1089

引用次数: 0