Case Reports in Urology最新文献

{"title":"Systemic Sporotrichosis With Testicular Involvement: Literature Review and Case Report.","authors":"Juan Eduardo Rios Rodriguez, Andreia Naiuf Lima Tuma, Aiko Iwamoto, Déborah Cristina Andrade Neves, Alexandre Kapteinat Lima, Felipe Nogueira Clementoni, Paula Heroso Moreira, Juan Felipe Martins Filgueiras, Luiz Sergio Santos, Osny de Barros Junior","doi":"10.1155/criu/4235866","DOIUrl":"10.1155/criu/4235866","url":null,"abstract":"<p><strong>Introduction: </strong>Sporotrichosis is an endemic fungal infection in Brazil, caused by a dimorphic fungus of the genus <i>Sporothrix</i>. Transmission occurs through traumatic inoculation from soil, contaminated plants, and zoonotic sources, mainly from cats, as well as through inhalation of conidia. It commonly presents as localized, lymphocutaneous, disseminated, or systemic forms. The testicles are among the organs that can be affected, often manifesting as a testicular mass. This work is aimed at analyzing a clinical case along with a bibliographic review on the testicular involvement of sporotrichosis.</p><p><strong>Case report: </strong>A 35-year-old male with positive HIV serology and a history of psychoactive substance use presented with disseminated ulcerated lesions that progressed over 1 month, with a positive blood culture for sporotrichosis. Upon hospitalization, a painless lump in the right testicle was diagnosed upon palpation and peripheral vascularization. An orchiectomy was performed, and anatomopathological analysis revealed the presence of <i>Sporothrix</i>.</p><p><strong>Discussion: </strong>Few reports on testicular sporotrichosis were found in the literature. Systemic forms are rare and are often associated with immunosuppression, particularly in cases of HIV and chronic alcoholism. This immunosuppression can favor the prevalence and dissemination of the fungus. The fungus also produces melanin, which aids in evading the immune system. The gold standard for diagnosis is culture. Furthermore, the treatment of choice is prolonged therapy with Amphotericin B, followed by itraconazole.</p><p><strong>Conclusion: </strong>Given the suspicion of disseminated sporotrichosis and the presence of a testicular nodule, the possibility of testicular sporotrichosis should be evaluated while maintaining attention to the differential diagnosis for neoplasia.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"4235866"},"PeriodicalIF":0.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Penile Metastases: Personalized Management in a Rare Oncologic Challenge.","authors":"R Hamal, A Feyaerts, S Thiry, H Dano, J Van Damme","doi":"10.1155/criu/7231390","DOIUrl":"10.1155/criu/7231390","url":null,"abstract":"<p><p>Secondary malignancy of the penis is a rare clinical entity. Nearly three-quarters of metastatic lesions in the penis originate from genitourinary and pelvic organs (such as the bladder, prostate, and colon). Less than 25% of penile metastases arise from extrapelvic primary sites and are usually associated with disseminated disease. Fewer than 50 cases of renal cancer metastasis to the penis have been described in the literature to date. We present the case of a 47-year-old male patient with a single metastasis of papillary renal cell carcinoma (pRCC) in the left corpus cavernosum. The patient had a history of left radical nephrectomy in 2004 and two lung wedge resections for unique metastases in 2007 and 2009. The patient complained of a growing, painless mass at the base of his penis. No other sites of metastasis were identified at staging. We performed a complete excision of the mass, and the final histopathological report confirmed the metastasis of pRCC with negative surgical margins. The patient remains treatment-free 8 years later.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"7231390"},"PeriodicalIF":0.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Curative Approach for Severe Hypertension in Select Patients With Underrecognized Rare Renal Tumors: A Case Report.","authors":"Noah Kevin McGreal, Zachary Dylan Winnegrad, Gregory Joseph Diorio, Ron Gefen, Ruth Carolina Birbe, Aileen Grace P Arriola","doi":"10.1155/criu/8149819","DOIUrl":"10.1155/criu/8149819","url":null,"abstract":"<p><p>Juxtaglomerular cell tumors (JCTs), also known as reninomas, are rare masses with an extremely low risk of malignancy, but their endocrine activity can lead to medication-resistant hypertension and electrolyte imbalances, which may harm patients. Approximately 150 cases have been documented in the literature. In this report, we describe the case of a 40-year-old male with a complex cystic renal mass, prior hemorrhagic strokes, and hypertension who underwent surgical resection. The final pathology confirmed a JCT, marking the first case on record diagnosed at our institution in 20 years. Following surgery, the patient's hypertension improved, and his need for medication decreased. We suggest that physicians managing renal masses that are otherwise suitable for surveillance should include JCT in their differential diagnosis and consider surgical removal if hypertension is present.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"8149819"},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conservative Management of Intrascrotal Polyorchidism in a 14-Year-Old Boy: A Case Report and Review of the Current Literature.","authors":"Panagiotis Nikolinakos, Abhisekh Chatterjee, Efstratios Christianakis, Ioannis Alexandrou, Nikolaos Chatzikrachtis, Elisavet Kotsi, Viktor Alargkof, Ivo Donkov, Samuel Bishara, Nikolaos Zavras, Joseph M Norris","doi":"10.1155/criu/5258413","DOIUrl":"10.1155/criu/5258413","url":null,"abstract":"<p><p>Polyorchidism, or supernumerary testes (SNTs), is a rare congenital condition, management of which remains debated, particularly in paediatric cases with other concomitant features. We report a case of intrascrotal polyorchidism in a 14-year-old boy managed surgically due to parental preference and the need for histological confirmation. The patient presented with a 2-week history of painless heaviness in the scrotum. Physical examination and Doppler ultrasonography revealed a 1.8 cm mass fused to the inferior pole of the left testicle with associated Grade 1 varicocele, hydrocele and testicular appendix. Although MRI of the scrotum was initially offered, the family declined in favour of timely histological confirmation. Surgical exploration confirmed a fused supernumerary testicle and a biopsy showed normal spermatogenesis; this was consistent with Type A3 triorchidism. The patient had no complications or recurrence of symptoms at 12-month follow-up. This case highlights the use of surgical exploration in selected intrascrotal polyorchidism cases where imaging can be inconclusive or histological confirmation is required. Parental concerns and long-term reassurance may also reasonably influence management decisions.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"5258413"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radical Cystectomy With Complete Duplication/Double Ureters.","authors":"David S Buchinsky, Jatan Shah, Nicolas Muruve, Jonathan Hakim","doi":"10.1155/criu/6433003","DOIUrl":"10.1155/criu/6433003","url":null,"abstract":"<p><p>Ureteric duplication is a variation of the urinary tract which can have significant impact in the urologic reconstructive setting. We present the incidental diagnosis and management of a 68-year-old man who was found to have a double ureter in the context of a radical cystectomy.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"6433003"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Primary Signet Ring Cell Carcinoma of the Urinary Bladder in a Young Woman.","authors":"Pavlo Synoverskyy, Sameh Hijazi, Thomas Krüer, Axel Haferkamp, Maximilian P Brandt","doi":"10.1155/criu/9204085","DOIUrl":"10.1155/criu/9204085","url":null,"abstract":"<p><p>Primary signet ring cell carcinoma of the urinary bladder (PSRCCB) is an exceedingly rare subtype of urinary bladder carcinoma, comprising 0.12%-0.6% of cases, with a poor prognosis. This case report details a distinctive case of a 32-year-old woman with PSRCCB, presenting without typical risk factors and posing diagnostic and therapeutic challenges. Initial symptoms included urinary tract infection and lower abdominal pain. Imaging and histological assessments identified a mucinous adenocarcinoma with signet ring cell components. The patient underwent curative open partial cystectomy, given her young age and localized tumor, avoiding lymphadenectomy and adjuvant chemotherapy due to complete tumor resection and absence of metastases. Postoperative follow-up showed no pathological findings, underscoring the importance of individualized treatment strategies in rare cancer cases. This case contributes to the limited data on PSRCCB and its management.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"9204085"},"PeriodicalIF":0.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12436014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urofacial Syndrome, an Expressive and Unmasking Sign of Voiding Dysfunction: Case Report and Review of the Literature.","authors":"Fawaz Alkeraithe, Waleed Altulayqi, Mutasim Alkhalifah, Faisal Alasmari, Mohammad Asiri, Ahmad Alhazmi","doi":"10.1155/criu/5548217","DOIUrl":"10.1155/criu/5548217","url":null,"abstract":"<p><p>Urofacial syndrome (UFS) is a rare autosomal recessive disorder characterized by voiding dysfunction, inverted facial expressions when smiling, and potential mutations in LRIG2 or HPSE2 genes. We report two sisters diagnosed with UFS who were managed using sacral neuromodulation (SNM). The first, aged 24, had recurrent UTIs, chronic urinary retention, and a trabeculated bladder without vesicoureteral reflux (VUR). Genetic testing identified a homozygous LRIG2 variant. Following SNM, her voiding function improved, reducing the frequency of catheterization. The second patient, aged 27, presented with a Grade 5 left-sided VUR, severe hydronephrosis, and a nonfunctioning left kidney. Urodynamic studies revealed an acontractile bladder. Post-SNM, her postvoid residual decreased to 30 mL, allowing independent voiding. Both displayed the hallmark inverted facial grimace. Diagnostic imaging and urodynamics confirmed neurogenic bladder, excluding spinal anomalies. Management included clean intermittent catheterization (CIC) and SNM, which enhanced bladder emptying and reduced catheter dependence. This case highlights SNM as a promising therapeutic option in UFS, improving voiding efficiency and quality of life. Early recognition of the distinctive facial expression is critical to prevent upper tract damage. Urologists should suspect UFS in patients with voiding dysfunction and abnormal facial expressions, considering SNM as a viable intervention. Further studies on SNM's role in UFS are warranted.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"5548217"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-Onset Penile Fracture After Collagenase <i>Clostridium histolyticum</i> Treatment for Peyronie's Disease in a 70-Year-Old Patient.","authors":"Matthew D Wainstein, Sonia E Masih, Timothy G Schuster","doi":"10.1155/criu/2126627","DOIUrl":"10.1155/criu/2126627","url":null,"abstract":"<p><p>Collagenase <i>Clostridium histolyticum</i> (CCH) injections are the gold standard for nonsurgical management of Peyronie's disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks postinjection. Here, we present a case of corporal rupture occurring 32 days after treatment. This is only the third reported case occurring 30 days after injection. While the risk of penis fracture likely decreases with time, these cases illustrate that the risk may extend beyond 4 weeks.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"2126627"},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Ureteric Small Bowel Fistula: A Case Report and Review of the Current Literature.","authors":"Panagiota Fallon, Melissa Matthews, Abhisekh Chatterjee, Dimitrios Sapountzis, Nikolaos Chatzikrachtis, Katie McComb, Samuel Bishara, Ivo Donkov, Konstantinos Charitopoulos, Panagiotis Nikolinakos","doi":"10.1155/criu/7232300","DOIUrl":"10.1155/criu/7232300","url":null,"abstract":"<p><p><b>Background:</b> Ureteric small bowel fistulas are rare entities, with limited reports in the literature. These pathological connections between the ureter and small bowel can lead to recurrent upper urinary tract infections and pose significant diagnostic and therapeutic challenges. The primary cause of ureteric small bowel fistula formation is iatrogenic intervention, such as percutaneous nephrolithotomy (PCNL) or abdominal surgery involving tissue resection. However, they can also arise spontaneously due to local chronic inflammation and infection. Given their rarity, there is no standardised management pathway, and the treatment approach should be individualised. <b>Case Presentation:</b> We present the case of a 57-year-old man presenting with a history of extensive locally advanced distal sigmoid carcinoma, managed with Hartmann's procedure with end colostomy followed by adjuvant radiotherapy and chemotherapy. He later developed a mid-ureteric small bowel fistula, presenting with urosepsis, a high-output stoma, deteriorating renal function and severe metabolic acidosis. Conservative management with regular ureteric stent exchanges every 3-4 months has successfully preserved renal function and improved his quality of life. Surgical closure was not pursued due to high operative risk, and repeat imaging has shown no evidence of persisting fistula, suggesting possible spontaneous closure. <b>Conclusion:</b> The treatment options for this ureteric small bowel fistula were limited. A lifelong nephrostomy was deemed unsuitable due to incompatibility with the patient's profession, and surgical intervention was associated with significant complexity due to the patient's history of malignancy and radiotherapy-related tissue changes. Therefore, a conservative strategy involving serial ureteric stent exchanges was pursued. Early recognition and individualised treatment of ureteric-enteric fistulas are essential, as timely intervention can significantly enhance prognosis and quality of life.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"7232300"},"PeriodicalIF":0.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Malignant Priapism Secondary to Muscle Invasive Bladder Cancer and Review of Palliative Management.","authors":"David Fenton, Simon Han, Adrianna Lee, Alexandra Hernandez Perez, Kristina Gam, Jung Woo Kwon, Piyush Agarwal, Omer Raheem","doi":"10.1155/criu/2340917","DOIUrl":"10.1155/criu/2340917","url":null,"abstract":"<p><p>Malignant priapism secondary to a genitourinary malignancy is a rare and late-stage oncological finding. A 72-year-old man with a past medical history of muscle-invasive bladder cancer treated with trimodal therapy presented with altered mental status, white discharge from his Foley catheter, and bilateral corporal rigidity. Initial pelvic magnetic resonance imaging demonstrated engorgement of the corporal bodies without obvious tumor invasion. The patient eventually underwent penile exploration and bilateral decompression, and a biopsy revealed high-grade urothelial carcinoma invading the corporal tissues. Despite current guidelines for priapism, we present a three-tiered approach to the management of malignant priapism.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"2340917"},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}