Case Reports in Orthopedics最新文献

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Massive Osteolysis in a Modern Total Knee Prosthesis. 现代全膝关节假体大量骨溶解。
Case Reports in Orthopedics Pub Date : 2021-10-20 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5507932
Emmanuel Gibon, Jacquelyn A Knapik, Hari K Parvataneni
{"title":"Massive Osteolysis in a Modern Total Knee Prosthesis.","authors":"Emmanuel Gibon, Jacquelyn A Knapik, Hari K Parvataneni","doi":"10.1155/2021/5507932","DOIUrl":"https://doi.org/10.1155/2021/5507932","url":null,"abstract":"Case An 82-year-old woman underwent right total knee replacement with a sequentially irradiated and annealed highly cross-linked polyethylene insert. At 9 years, she was found to have a massive femoral osteolysis with an impending fracture. Conclusion This case demonstrates a rare occurrence of massive femoral osteolysis, requiring revision surgery, with a sequentially irradiated and annealed highly cross-linked polyethylene.","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"5507932"},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Distal Extrusion of Kuntscher Intramedullary Nail. Kuntscher髓内钉自发性远端挤压。
Case Reports in Orthopedics Pub Date : 2021-10-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5587325
W B Teh, R Kuharajan, A H Noor Shafika, I G Nur Azhani
{"title":"Spontaneous Distal Extrusion of Kuntscher Intramedullary Nail.","authors":"W B Teh,&nbsp;R Kuharajan,&nbsp;A H Noor Shafika,&nbsp;I G Nur Azhani","doi":"10.1155/2021/5587325","DOIUrl":"https://doi.org/10.1155/2021/5587325","url":null,"abstract":"<p><p>Migration of femoral Kuntscher intramedullary nail (K-nail) proximally or distally within the femoral medullary cavity is a well-known documented complication, but spontaneous extrusion of a distally migrated K-nail is a rare complication. This is a case report of a 33-year-old lady who complained of sudden onset left knee pain and presented with spontaneous extrusion of a Kuntscher nail 12 years postinsertion. She underwent a successful K-nail removal surgery and showed a good clinical outcome after 6 months of outpatient follow-up.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"5587325"},"PeriodicalIF":0.0,"publicationDate":"2021-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39566083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'Within Ring' Concept Treatment for Displaced H-Shaped Type IVb Fragility Fractures of the Pelvis. “环内”概念治疗移位的h型IVb型骨盆脆性骨折。
Case Reports in Orthopedics Pub Date : 2021-10-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6864910
Yohei Yanagisawa, Yusuke Eda, Shotaro Teruya, Hisanori Gamada, Masashi Yamazaki
{"title":"'Within Ring' Concept Treatment for Displaced H-Shaped Type IVb Fragility Fractures of the Pelvis.","authors":"Yohei Yanagisawa,&nbsp;Yusuke Eda,&nbsp;Shotaro Teruya,&nbsp;Hisanori Gamada,&nbsp;Masashi Yamazaki","doi":"10.1155/2021/6864910","DOIUrl":"https://doi.org/10.1155/2021/6864910","url":null,"abstract":"<p><strong>Introduction: </strong>Sacroiliac rod fixation (SIRF) preserves the mobility of L5/S1 (lumber in the pelvis), as a surgical procedure for high-energy pelvic ring fractures. The concept of SIRF method without pedicle screws into L4 and L5 is called 'within ring' concept. <i>Case Presentation</i>. We report here the clinical results of 'within ring' concept treatment with sacroiliac rod fixation for a case of displaced H-shaped Rommens and Hofmann classification type IVb fragility fractures of the pelvis (FFP), which A 79-year-old woman had been difficult to walk due to pain that had been prolonged for more than one month since her injury. The patient was successfully treated with SIRF, no pain waking with a walking stick and returned to most social activities including living independently within 6 months of the operation.</p><p><strong>Conclusion: </strong>SIRF is useful because it can preserve the mobility in the lumbar pelvis; not including the lumbar spine in the fixation range like spino pelvic fixation is a simple, safe, and low-invasive internal fixation method for displaced H-shaped type IVb fragility fractures of the pelvis.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6864910"},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39555439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dislocation after Posterior Stabilized Primary Total Knee Replacement: A Rare Complication in Four Cases. 后路稳定全膝关节置换术后脱位:4例罕见并发症。
Case Reports in Orthopedics Pub Date : 2021-10-13 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9935401
W Spierenburg, E L A R Mutsaerts, J J A M van Raay
{"title":"Dislocation after Posterior Stabilized Primary Total Knee Replacement: A Rare Complication in Four Cases.","authors":"W Spierenburg,&nbsp;E L A R Mutsaerts,&nbsp;J J A M van Raay","doi":"10.1155/2021/9935401","DOIUrl":"https://doi.org/10.1155/2021/9935401","url":null,"abstract":"<p><strong>Introduction: </strong>Dislocation of a total knee arthroplasty is a rare complication that has rarely been described, while the total knee arthroplasty is frequently performed. From literature, we know patient-related factors, like obesity, neuropsychiatric disease, and severe valgus or varus deformity, are associated with higher risk of dislocation. We show our cases for awareness of the risk factors for surgeons. <i>Case Presentations</i>. We present four patients with a dislocation after a total knee arthroplasty. We compare these case reports with previous literature and show the most important risk factors for these dislocations. In our cases, three of them suffered from obesity, which possibly has contributed to the dislocation. Three patients did have instability which emphasizes the importance of ligament balancing while performing a total knee replacement. In all cases, an exchange of the polyethylene liner was performed.</p><p><strong>Conclusion: </strong>Implant-related factors and surgical technique as well as patient-related factors can contribute to this uncommon complication. Obesity, neuropsychiatric disorders, and a severe valgus or varus deformity are important patient-related risk factors. Our cases show these risk factors too. Some of these risk factors were encountered as well as other comorbidity factors. Such risk factors must be taken into consideration when deciding whether to perform a total knee arthroplasty. This stresses the importance of patient education and shared decision-making before performing a total knee replacement.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9935401"},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39555440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Osteolysis following PE Wear of a Hastings Head on a Monoblock Hip Stem. PE在单块髋关节干上佩戴Hastings头后发生骨溶解。
Case Reports in Orthopedics Pub Date : 2021-10-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9989395
Sarah Fischer, Valerie Polster, Miriam Ruhr, Robert Hube, Michael M Morlock
{"title":"Osteolysis following PE Wear of a Hastings Head on a Monoblock Hip Stem.","authors":"Sarah Fischer,&nbsp;Valerie Polster,&nbsp;Miriam Ruhr,&nbsp;Robert Hube,&nbsp;Michael M Morlock","doi":"10.1155/2021/9989395","DOIUrl":"https://doi.org/10.1155/2021/9989395","url":null,"abstract":"<p><p>We report a case of extended osteolysis, requiring a third revision of the left hip in an 85-year-old man 46 years after index operation. Major polyethylene (PE) wear occurred due to a missmatched combination of a bipolar Hastings head with a PE liner and head damage of the originally maintained stem. This case demonstrates that bipolar heads should not be used with PE cup liners since the respective bearing diameters cannot be guaranteed to match due to missing specifications. Furthermore, putting a Hastings head on an already damaged head of the stem should be omitted and rather the stem should initially be revised.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9989395"},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39529126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature. 小儿髓外硬膜外脊髓畸胎瘤1例报告及文献复习。
Case Reports in Orthopedics Pub Date : 2021-10-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6702972
David G Deckey, Andrea Fernandez, Nina J Lara, Steve Taylor, Jamal McClendon, David M Bennett
{"title":"Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature.","authors":"David G Deckey,&nbsp;Andrea Fernandez,&nbsp;Nina J Lara,&nbsp;Steve Taylor,&nbsp;Jamal McClendon,&nbsp;David M Bennett","doi":"10.1155/2021/6702972","DOIUrl":"https://doi.org/10.1155/2021/6702972","url":null,"abstract":"<p><strong>Background: </strong>Teratomas in the pediatric population are most commonly found in the sacrococcygeal region. Pediatric intraspinal teratomas, however, are an exceedingly rare central nervous system (CNS) neoplasm. The clinical presentation of these intraspinal neoplasms can vary significantly and thus can be difficult to identify in infants less than one year of age where verbal expression and motor development are still lacking. <i>Case Description</i>. A 7-month-old, previously healthy male presented with a thoracic scoliosis and an asymptomatic right midupper thoracic spinal prominence present since birth. MRI revealed an extensive heterogenous mass in the right epidural space from T5-T6 and the right paravertebral space, resulting in severe spinal stenosis. <i>Outcome</i>. Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. The final tumor was consistent with a mature teratoma. The surgical resection was performed without any immediate complications.</p><p><strong>Conclusions: </strong>Extramedullary epidural teratomas are exceptionally rare tumors in the pediatric population. Clinical presentation can be ambiguous, particularly in an infant. MRI was useful in suggesting a teratoma as a potential diagnosis and for postoperative surveillance for recurrence. However, histopathological analysis remains the gold standard for definitive diagnosis. Surgical resection is the mainstay of treatment, especially in the setting of cord compression and progressive loss of motor function. Close follow-up is crucial to monitor for progressive spinal deformity or recurrence.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6702972"},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Femoral Neck Insufficiency Fracture due to Tumor-Induced Osteomalacia. 肿瘤性骨软化致股骨颈不全骨折1例。
Case Reports in Orthopedics Pub Date : 2021-10-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6668006
Yu Inoue, Tomoaki Fukui, Keisuke Oe, Shinya Hayashi, Teruya Kawamoto, Ryosuke Kuroda, Takahiro Niikura
{"title":"A Case of Femoral Neck Insufficiency Fracture due to Tumor-Induced Osteomalacia.","authors":"Yu Inoue,&nbsp;Tomoaki Fukui,&nbsp;Keisuke Oe,&nbsp;Shinya Hayashi,&nbsp;Teruya Kawamoto,&nbsp;Ryosuke Kuroda,&nbsp;Takahiro Niikura","doi":"10.1155/2021/6668006","DOIUrl":"https://doi.org/10.1155/2021/6668006","url":null,"abstract":"<p><p>Tumor-induced osteomalacia (TIO) is a rare skeletal disease caused by hypersecretion of fibroblast growth factor 23 (FGF-23) from neoplasms of mesenchymal origin; patients with TIO present with insufficiency fractures, progressive bone pain, and delayed fracture unions. Herein, we report the case of a 48-year-old man with an insufficiency fracture in his left femoral neck associated with TIO. The causative tumor located in the patient's maxillary sinus had been resected; however, complete resection was impossible due to the location of the tumor. Therefore, the patient's osteomalacia persisted, and he experienced a left femoral neck fracture in the absence of severe trauma. Because delayed fracture union was anticipated in this patient, we performed an internal fixation using an implant with a lateral plate for angular stability and multiple screws for rotational stability. Although fracture union took 15 months, the patient's postoperative course was uneventful, and he could walk without any symptoms or assistance at his most recent follow-up 30 months after surgery. In TIO, hypersecretion of FGF-23 leads to increased renal excretion of phosphorus, increased bone resorption of calcium and phosphorus, decreased osteoblastic bone mineralization, and decreased gastrointestinal absorption of calcium and phosphorus, leading to insufficiency fractures and delayed fracture unions. Diagnosis of TIO is often delayed due to its rarity and vague symptoms. Total resection of the causative tumor is the optimal treatment; however, in cases wherein complete tumor resection is impossible, drug therapy may be insufficient, and the underlying TIO pathology, including bone fragility, may persist. Early diagnosis of TIO is important for preventing insufficiency fractures; however, when fractures are unavoidable, the surgical treatment of femoral neck fractures in patients with osteomalacia should account for a longer time frame for complete fracture union and therefore utilize implants with sufficient stability.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6668006"},"PeriodicalIF":0.0,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications after Dynamic Hip Screw Osteosynthesis of Proximal Femoral Fractures at Army Instructional Hospital-Libreville. 利伯维尔陆军教学医院股骨近端骨折动态髋螺钉骨合成术后并发症。
Case Reports in Orthopedics Pub Date : 2021-10-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4177203
F M Bombah, M Diawara, B Y Ekani, T Nana, A Mikiela
{"title":"Complications after Dynamic Hip Screw Osteosynthesis of Proximal Femoral Fractures at Army Instructional Hospital-Libreville.","authors":"F M Bombah, M Diawara, B Y Ekani, T Nana, A Mikiela","doi":"10.1155/2021/4177203","DOIUrl":"10.1155/2021/4177203","url":null,"abstract":"<p><p>The DHS system is an effective means of open reduction and internal fixation of proximal femur fractures. Postoperative complications are little described and deserve to be studied for better preventive and curative treatment. We report the observations of five (5) patients who presented postoperative complications specific to the DHS system at army instructional Hospital-Libreville. These described complications are related to deterioration of internal fixation leading to callus, nonunion, or infection. Those found are the cut out phenomenon, avascular necrosis of the femoral head, and the fracture of the DHS system. All these complications required surgical revision without functional repercussions at the last follow-up. Complications of internal fixation by the DHS system can be avoided by rigorous asepsis, adequate indications for surgery, and rigorous surgical techniques. Good management can restore hip function.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"4177203"},"PeriodicalIF":0.0,"publicationDate":"2021-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39515699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salvaging the Digit in Invasive Subungual Malignancies Using a Triple Technique under Awake Local Anesthesia. 清醒局麻下三合一技术抢救侵入性甲下恶性肿瘤的手指。
Case Reports in Orthopedics Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4648627
Samer Abdel Al, Mohamad K Abou Chaar, Ala'a Aldeen Alkhatib, Muhamad Al-Qawasmi, Mohammad Barham, Sameer Yaser, Samer Salah, Abed Al Raheem Suleiman, Wafa Asha
{"title":"Salvaging the Digit in Invasive Subungual Malignancies Using a Triple Technique under Awake Local Anesthesia.","authors":"Samer Abdel Al,&nbsp;Mohamad K Abou Chaar,&nbsp;Ala'a Aldeen Alkhatib,&nbsp;Muhamad Al-Qawasmi,&nbsp;Mohammad Barham,&nbsp;Sameer Yaser,&nbsp;Samer Salah,&nbsp;Abed Al Raheem Suleiman,&nbsp;Wafa Asha","doi":"10.1155/2021/4648627","DOIUrl":"https://doi.org/10.1155/2021/4648627","url":null,"abstract":"<p><strong>Introduction: </strong>Amputation for subungual malignancy (SUM) was thought to be the gold standard in preventing recurrence and metastasis. The rationale behind this aggressive treatment was never based on scientific evidence. Even though multiple recent studies supported more conservative management by illustrating successful results of the digit salvage technique, especially for \"in situ\" SUM, this salvage approach is not well supported for the more aggressive type of the \"invasive\" SUM; herein, we salvaged two cases of \"invasive\" SUM. <i>Case Presentation</i>. We present two cases of invasive SUM without radiographic evidence of intraosseous involvement, where we avoided digit amputation for both invasive subungual squamous cell carcinoma of the thumb and invasive subungual melanoma of the ring finger. Both were salvaged by using a triple technique under awake local anesthesia which included (I) radical excision of the nail bed unit including both eponychium and periosteum, (II) dorsal cortical bone shaving using a high-speed burr for the distal phalanx, and (III) flap coverage. Brunelli flap was used for the thumb in the first case, and V-Y plasty combined with proximal nail fold advancement flap was used for the ring finger in the second case. There was no evidence of local or distant recurrence, with a good functional outcome after 2.5 years in the first case and 2 years in the second.</p><p><strong>Conclusion: </strong>Ensuring complete resection with negative margins while preserving the functionality of the affected digit is considered to be the optimal challenge in treating \"invasive\" subungual malignancies. These two case reports contribute by reporting a successful digit salvage. The safety of this procedure could be confirmed by larger series and longer follow-up periods.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"4648627"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient. 成人肩胛骨血管瘤样纤维组织细胞瘤伴EWSR1-CREB1融合1例。
Case Reports in Orthopedics Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9434222
Hiroshi Kobayashi, Naohiro Makise, Aya Shinozaki-Ushiku, Yuki Ishibashi, Masachika Ikegami, Shinji Kohsaka, Tetsuo Ushiku, Katsutoshi Oda, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano, Sakae Tanaka
{"title":"Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient.","authors":"Hiroshi Kobayashi,&nbsp;Naohiro Makise,&nbsp;Aya Shinozaki-Ushiku,&nbsp;Yuki Ishibashi,&nbsp;Masachika Ikegami,&nbsp;Shinji Kohsaka,&nbsp;Tetsuo Ushiku,&nbsp;Katsutoshi Oda,&nbsp;Kiyoshi Miyagawa,&nbsp;Hiroyuki Aburatani,&nbsp;Hiroyuki Mano,&nbsp;Sakae Tanaka","doi":"10.1155/2021/9434222","DOIUrl":"https://doi.org/10.1155/2021/9434222","url":null,"abstract":"<p><strong>Background: </strong>Angiomatoid fibrous histiocytoma (AFH) is a rare intermediate malignant tumor that arises mainly in soft tissues, especially in the superficial extremities of patients younger than 30 years. There have been a few reports of AFH arising from sites other than soft tissue, including bone, and unusual site and age make it difficult to diagnose this rare tumor. <i>Case Presentation</i>. Here, we present a case of a 54-year-old man who was examined for chest pain, and computed tomography (CT) incidentally detected a bone tumor at the scapula with destruction of cortical bone and invasion into soft tissue. Magnetic resonance imaging revealed multiple cystic components with fluid-fluid levels. FDG-PET showed uptake at the axillary lymph node. The CT-guided needle biopsy revealed spindle cell sarcoma on histopathology. After neoadjuvant chemotherapy, a scapulectomy was performed. The final postresection histopathological diagnosis was the same as the preoperative diagnosis, and no obvious chemotherapeutic effect was observed. Next-generation sequencing of RNA isolated from paraffin-embedded tumor tissue revealed that these lesions harbored the <i>EWSR1-CREB1</i> fusion gene, and the tumor was diagnosed as AFH. C-reactive protein level, which was elevated preoperatively, decreased after the operation, and there was no recurrence or metastasis 5 years after the treatment.</p><p><strong>Conclusion: </strong>The diagnosis of AFH is difficult when the tumor has an atypical presentation. Comprehensive genomic analysis, especially RNA sequencing, is efficient in diagnosing this rare tumor. Moreover, magnetic resonance imaging findings identical to AFH in soft tissue, the presence of paraneoplastic symptoms such as elevated inflammatory markers, and lymph node swelling were clues towards suspecting this tumor.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9434222"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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