{"title":"Rare Malignancies of the Female Genital Tract","authors":"Rijuta Joshi, G. Baral","doi":"10.3126/njog.v15i1.29334","DOIUrl":"https://doi.org/10.3126/njog.v15i1.29334","url":null,"abstract":"Aims: To analyze rare female genital tract malignancies. Method: This is retrospective descriptive study as a census of all rare female genital tract malignancies in two years from 2017 to 2019 at Paropakar Maternity and Women’s Hospital in Kathmandu. Data were retrieved from medical record and entered into Microsoft Excel and SPSS 16 window for analysis. Results: There were 156 cases of female genital tract malignancies including 128 common types and 28 rare types. Majority fell under 4150 years (n=44; 28.2%) followed by over 60 (n=41; 26.2%) and 51-60 years (n=34; 21.8%). Among ovarian tumors, the rare varieties were adult granulosa cell tumor (n=4), immature teratoma (n=3) and single case each of yolk sac tumor, dysgerminoma, malignant mixed germ cell tumor, carcinoid tumor, juvenile granulosa cell and sertoli cell tumor. There were one case each of carcinosarcoma, serous carcinoma and endometrial stromal carcinoma; two cases each of leiomyosarcoma and choriocarcinoma while there was a single case of placental site trophoblastic tumor. The rare cervical malignancies were small cell (n=2), and clear cell carcinoma (n=1). There were single cases each of basal cell carcinoma of vulva, verrucus carcinoma, fibromyxoid sarcoma of Bartholin’s gland and malignant melanoma of vagina. Conclusion: Rare female genital tract cancers were found mostly from the ovary followed by uterus; 18% of total cancers were rare types.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"1 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90962541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction Notice for Abstract \"Challenges faced by women after repair of genital tract fistula: An observational study in Tanganika Province, Democratic Republic of Congo\"","authors":".. Editor","doi":"10.3126/njog.v14i1.27572","DOIUrl":"https://doi.org/10.3126/njog.v14i1.27572","url":null,"abstract":"On 6th February 2020 the Editorial Board of Nepal Journal Obstetrics and Gynaecology agreed to retract the Abstract ‘Challenges faced by women after repair of genital tract fistula: An observational study in Tanganika Province, Democratic Republic of Congo’ published in Nepal Journal of Obstetrics and Gynaecology, Vol.13(2) 2018 (DOI: https://doi.org/10.3126/njog.v13i2.21914 ). This retraction was requested by the authors: C.A. Notia, A. Philibert and D.M. Mukwege. We apologise for any inconvenience.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78117609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cervical cancer screening by conventional Pap smear versus liquid based cytology","authors":"Subi Basnyat, G. Baral, K. Malla","doi":"10.3126/njog.v14i2.28435","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28435","url":null,"abstract":"Aims: To evaluate Liquid Based Cytology (LBC) diagnostic performance compared with Conventional Pap Smear (CPS) for cervical cancer screening and to compare the sensitivity and specificity of the two cytology methods with gold standard cervical biopsy. \u0000 Methods: This is a hospital based cross-sectional study conducted from April 2017 to April 2018 in 110 sample randomly selected at gynecology OPD in Paropakar Maternity and Women’s Hospital. Paired samples (CPS and LBC) were taken from the same patient. Abnormal epithelial lesion detected in LBC and CPS was sent for biopsy. Bethedsa reporting system was followed and data analyzed in terms of diagnostic accuracy. \u0000 Results: LBC vs CPS for satisfactory report was 96.4% vs 91.8% while unsatisfactory was 3.6% vs 1.8% (p=0.02). The detection of premalignant lesions was ASCUS 2.7%, HSIL 4.5%, ASCUS-H 1.8% and LSIL 0.9% by LBC while by CPS- ASC-US 0.9%, HSIL 3.6%, LSIL 1.8% and ASC-H 0.9% were detected. The sensitivity and specificity of LBC vs CPS was 100% vs 88% and 81.8% vs 99% respectively. The positive predictive and negative predictive value of LBC vs CPS was 81.8% vs 88% and 100% vs 99% respectively. \u0000 Conclusions: Cell pick-up was satisfactory in both LBC and CPS. The sensitivity and positive predictive value of CPS is similar whereas the positive predictive value of LBC is less than its sensitivity. Cervical cancer screening with CPS is effective alternative over LBC by its cost and level of accuracy.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"1 1","pages":"22-25"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84563326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Paudel, A. Chalise, G. Dangal, T. Bhandari, G. Baral
{"title":"Pelvic Organ Prolapse in Countries of Different Economy: A Systematic Review","authors":"S. Paudel, A. Chalise, G. Dangal, T. Bhandari, G. Baral","doi":"10.3126/njog.v14i2.28436","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28436","url":null,"abstract":"Aims: This review was done to identify the reported prevalence rate of pelvic organ prolapse among the different world populations. \u0000Methods: Systematic review of Pelvic Organ Prolapse (POP) using the PRISMA checklist; PubMed database was searched on reportingthe prevalence of POP and its management measures in January 2020. Medical Subject Headings (MeSH) like \"Pelvic Organ Prolapse\"OR \"Uterine Prolapse\" OR “Vaginal Wall Prolapse” OR \"Cystocele\"AND \"Prevalence [key word/s]\" were used. Additional articles were identified through the reference list of the retrieved articles. \u0000 Results: Out of 91 screened articles, 46 full articles were eligible and only 15 satisfied by selection criteria for the systematic review.The methodological score rated for the quality of studies is 4.5±1.7 (range=2-7) out of 8 points. The mean prevalence of POP diagnosis was 40%; with 42.44% in low and lower-middle-income countries,and 35.56%in upper-middle and high-income countries. Increasing age and parity, body mass indexand fetal macrosomia were found to be the significant risk factors irrespective of the country’s economy. \u0000Conclusions:The low and lower-income countries have almost twice the burden of prolapse than the countries of the higher economy. The major risk factors associated with prolapse remain common in all countries irrespective of national income or development. \u0000 ","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"46 1","pages":"7-21"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78470543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Career in Obstetrics and Gynecology; to be or Not to be: A Study of Intern Doctors in a Nepalese Medical College","authors":"S. Aryal, D. Shrestha","doi":"10.3126/njog.v14i2.28437","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28437","url":null,"abstract":"Aims: To find the preference of career in Obstetrics and Gynecology among interns at the end of internship and factors influencing this choice. \u0000 Methods: A semistructured questionnaire was distributed to interns at the end of a one year rotatory internship. Demographic factors and clinical exposure in Obstetrics and Gynecology (ObGyn) were assessed using chi-square test and attitudinal factors were measured using 5 point Likerts scale. This was compared with interns choosing other subjects. Mean score on Likerts scale was compared with independent t-test. Logistic regression analysis was used to predict independent factors affecting career choice in ObGyn. \u0000Results: Out of 174 interns, 22 (12.6%) chose ObGyn as the first career choice. Female gender (OR=1.46), urban residence (OR=1.21) and having a doctor in the family (OR=1.22) were factors associated with choosing ObGyn. Social commitment (p=0.027), high income potential (p=0.000), focus on urgent care (p= 0.000), gratifying practice (p=0.043) and short postgraduate training (p=0.000) were attitudinal factors related to this choice. \u0000Conclusions: Though ObGyn is a popular choice, students tend to change minds against it throughout medical school, influenced by various experiences. Department of ObGyn has a major responsibility to develop role models and encouraging mentors so that students choose ObsGyn with interest and do not regret the choice till the end of medical school.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"27 1","pages":"36-41"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90987561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of urine protein creatinine ratio and 24 hours urine protein in detecting preeclampsia","authors":"Nesuma Sedhain, Jageshwor Gautam, G. Baral","doi":"10.3126/njog.v14i2.28439","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28439","url":null,"abstract":"Aim: To assess the diagnostic accuracy of spot urine protein-creatinine ratio for detection of proteinuria in Preeclampsia. \u0000Methods: Cross Sectional Descriptive Study was conducted in a total of 38 pregnant women in Paropakar Maternity and Women’s Hospital in study period of 3 month. The correlation between protein- creatinine ratio in spot urine samples and urinary protein excretion in 24-hour collections were analyzed. \u0000 Results: Comparison of 24 hours urinary protein and protein- creatinine ratio in women with preeclampsia shows a significant correlation (r=0.911, p<0.0001). The cut-off protein-creatinine ratios which gave maximum area under the curve for 300mg protein for 24hrs was 0.27 (sensitivity: 94.6%, specificity: 100%, PPV: 100%, NPV: 33.3%); 2000 mg urine protein excretion was 2.1 (sensitivity and specificity of 100%); 3000mg protein excreted for 24hours was 3.0 (sensitivity: 83.3%, \u0000specificity: 92.3%, PPV: 83.3%, NPV: 93.3%. Area under the ROC for 24hours urine total protein of >300mg, >2000mg and >3000mg/day were 0.946 (95%CI 0.873-1.019), 1 (95% CI 1.00-1.00) and 0.957 (95%CI 0.897- 1.016) respectively. \u0000Conclusions: Spot urine protein-creatinine ratio is as accurate as to 24 hours urine protein determination of proteinuria in Preeclampsia.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"70 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91182840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Shrestha, Rosy Malla, R. Manandhar, R. Khatri, C. Shrestha, R. Khatiwada, Pratik Silwal, Sahadev Bidari, M. Maharjan, R. Jasaraj, Bhesh Karki
{"title":"Prevalence and Outcome of Induction of Labor in a Tertiary Care Center of Kathmandu, Nepal","authors":"D. Shrestha, Rosy Malla, R. Manandhar, R. Khatri, C. Shrestha, R. Khatiwada, Pratik Silwal, Sahadev Bidari, M. Maharjan, R. Jasaraj, Bhesh Karki","doi":"10.3126/njog.v14i2.28441","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28441","url":null,"abstract":"Aim: To study the prevalence of induction of labor and obstetric and neonatal outcome among delivery cases in the maternity unit of a tertiary care center. \u0000Methods: This is a prospective cross-sectional study conducted on pregnant ladies presenting to maternity unit of Shree Birendra Hospital, Chhauni over a period of six months from March to August 2017. All pregnant ladies in labor during the study period were enrolled. Induction of labor, mode of delivery, perinatal outcome (gestational age at delivery, birth weight), and maternal complications if any were recorded. \u0000 Results: Among 497 deliveries in the study period, induction of labor was performed in 117 (23.5%) cases with post-date pregnancy being the most common indication. Induction was successful with vaginal deliveries in 82(70.1%) cases, while in the rest, IOL failed. Among the induced cases, 17 (14.5%) neonates had poor APGAR at 5 minutes and there was significant association of IOL with low APGAR. There was normal post-natal recovery in 108 (92.3%) induced cases while 9 (7.7%) cases developed some maternal complications. IOL has no significant association with maternal and neonatal complications or perineal injury (p>0.05). \u0000Conclusions: The prevalence of induction in this center is slightly higher than other centers. The IOL has significant association with low APGAR at 5 minutes but no significant association with the neonatal and maternal complications.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"1 1","pages":"54-56"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89560158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ectopic pregnancy in the fallopian tube of the rudimentary horn of uterus unicornis","authors":"R. Abdus-salam, R. Adeoti","doi":"10.3126/njog.v14i2.28445","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28445","url":null,"abstract":"Ectopic gestation may occur in the fallopian tubes, cervix, ovary or the abdominal cavity. It results from abnormal implantation of the embryo at sites other than the endometrial cavity of the uterus. Congenital anomalies of the fallopian tubes and uterus may predispose to abnormal implantation of the embryo at other sites hence an ectopic gestation results. We describe a rare case of a 30 year old woman with ruptured ectopic gestation located in the fallopian tube of the rudimentary horn of a uterus unicornis. She was evaluated, resuscitated and had a successful surgical intervention.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"12 2 1","pages":"67-70"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74418349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Need of Fellowship Training in Nepal: Obstetrics and Gynecology Sub-specialties Are Not Left Behind","authors":"G. Dangal, G. Baral","doi":"10.3126/njog.v14i2.28443","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28443","url":null,"abstract":"There is increasing demand of more and more specialized services and trainings in medical field and Obstetrics and Gynecology is not an exception to it. As a sub-specialty training Gynecological oncology and Urogynecology fellowships have become a developmental milestone under National Academy of Medical Sciences since 2018. Resource utilization for academic purpose in public-private-partnership model is beneficial.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"30 1","pages":"62-64"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72971228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Specialty training in Medicine","authors":"G. Baral","doi":"10.3126/njog.v14i2.28432","DOIUrl":"https://doi.org/10.3126/njog.v14i2.28432","url":null,"abstract":"Medical service is unconditional act with good faith that doesn’t always follow the theory ofeconomics and business. Specialty training is must and sub-specialty is the demand of time.Medical education and trainings are delivered according to the desired target within the definedterritory.","PeriodicalId":30234,"journal":{"name":"Nepal Journal of Obstetrics and Gynaecology","volume":"69 1","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84459598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}