Minerva Surgery最新文献

{"title":"Risk factors for perioperative allogenic blood transfusion and its impact on early recurrence after cytoreductive surgery with or without intraperitoneal hyperthermic chemotherapy.","authors":"Ana Tejedor, Eva Bassas, Marina Vendrell, Lana Bijelic, Graciela Martinez-Palli","doi":"10.23736/S2724-5691.25.10946-5","DOIUrl":"10.23736/S2724-5691.25.10946-5","url":null,"abstract":"<p><strong>Background: </strong>Allogenic blood transfusion (ABT) is associated with postoperative complications and possibly early recurrence (ER). after oncologic surgery. We sought to investigate predictors and impact of ABT in cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC).</p><p><strong>Methods: </strong>All patients who underwent CRS±HIPEC from June 2020 to January 2022 at a high-volume center were included. Patients were classified according to whether they had received a perioperative ABT during the entire hospitalization period. ER was defined as the time from complete resection to the first recurrence (local or distant) or death, whichever occurred first, within 2 years after surgery. Multivariate logistic regression and Cox analysis identified risk factors for ABT and ER, respectively.</p><p><strong>Results: </strong>Of 168 patients, 56 (33.3%) required ABT (mean 2.4 [2.2] red blood cell units). Multivariate logistic analysis showed that hemoglobin levels 24-h before surgery (odds ratio [OR] 0.5; 95% confidence interval [CI]: 0.4 to 0.7), intraoperative fluid balance (OR 1.01; 95% CI: 1.01 to 1.02) and time of surgery (OR 1.1; 95% CI: 1.1 to 1.1) were independently associated with ABT. Multivariate Cox regression identified time of surgery (hazard ratio [HR] 1.01, 95% CI: 1.01 to 1.02) and previous systemic chemotherapy (HR 2.5, 95% CI: 1.3 to 4.8) as risk factors for ER, while ABT was not (P=0.078).</p><p><strong>Conclusions: </strong>Lower preoperative hemoglobin levels, higher intraoperative fluid balance, and longer surgery time are risk factors for ABT. Longer operative time and previous systemic chemotherapy are associated with early recurrence.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"431-441"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed tracheal perforation following thyroidectomy successfully managed with bedside drainage.","authors":"Young J Park, Ohjoon Kwon","doi":"10.23736/S2724-5691.25.10984-2","DOIUrl":"https://doi.org/10.23736/S2724-5691.25.10984-2","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 6","pages":"492-493"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To mesh or not to mesh? Comparing safety, efficacy and outcomes of mesh and suture repair for Amyand's hernia: a systematic review.","authors":"Georgios Gerasopoulos, Foteini Karagianni, Panagiotis Routis, Spyridon Nikas, Antonios Gklavas","doi":"10.23736/S2724-5691.25.10960-X","DOIUrl":"10.23736/S2724-5691.25.10960-X","url":null,"abstract":"<p><strong>Introduction: </strong>Amyand's hernia (AH) is a relatively rare type of inguinal hernia, characterized by the presence of the appendix inside the hernia sac. The aim of this study is to examine the role of prosthetic mesh in AH repair compared to the traditional suture repair techniques regarding safety, efficacy and various postoperative complications.</p><p><strong>Evidence acquisition: </strong>A systematic review of MEDLINE via PubMed, Scopus and Google Scholar was performed, aligned with the PRISMA guidelines. All studies in English language reporting AH repair using mesh or suture techniques in adults including more than 5 patients were included.</p><p><strong>Evidence synthesis: </strong>Twelve studies reported a total of 123 patients with AH, 58 of which were repaired using prosthetic mesh and 71 with traditional suture techniques. The overall presence of an inflamed appendix was 58.5%. Appendicitis was present in 12.7% of the mesh repair group compared to a 95.5% of the suture repair group. Surgical site infections (SSIs) were 3.4% of all complications in the mesh group compared to 6.8% in the suture repair group. Extended hospital stay of more than 10 days was observed in 12.7 in the mesh group compared to 7.3% of the suture repair group.</p><p><strong>Conclusions: </strong>The most technically challenging cases with septic conditions are appropriate for suture repair only, while mesh repair is usually performed in AH cases without appendix inflammation and is more commonly used in conjunction with appendix reduction into the abdominal cavity rather than appendicectomy.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"485-491"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The differentially expressed mRNA and its network construction in nerve injury associated with thermal radiation disease based on GEO database.","authors":"Xiping Luo, Hanzhi Zou, Wenxin Yang","doi":"10.23736/S2724-5691.23.10175-4","DOIUrl":"10.23736/S2724-5691.23.10175-4","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"498-500"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anpentatin preconditioning regulates SIRT1/FoxO1 pathway to alleviate cerebral ischemia-reperfusion injury in rats.","authors":"Shengrong Huang, Jiamin Wang, Zhibiao Luo, Keshang Chen, Min Xia, Kaiyi Wu, Nan W Liu","doi":"10.23736/S2724-5691.23.10007-4","DOIUrl":"10.23736/S2724-5691.23.10007-4","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"494-495"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-based interaction and risk factor identification between abnormal hepatic blood flow and portal hypertension.","authors":"Quanlong Yang, Xumin Jian, Ce Shi, Shengxia Ni","doi":"10.23736/S2724-5691.24.10390-5","DOIUrl":"https://doi.org/10.23736/S2724-5691.24.10390-5","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of expression levels of B7-H6 and PPARG in patients with breast cancer and clinical significance of Zigen oyster decoction.","authors":"Li Li, Jian Sun","doi":"10.23736/S2724-5691.25.10562-5","DOIUrl":"https://doi.org/10.23736/S2724-5691.25.10562-5","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive subharmonic-aided pressure estimation for surgical management of portal hypertension: a clinical study in TIPS patients.","authors":"Ziyin Zhu, Si Liang, Linxue Qian","doi":"10.23736/S2724-5691.25.10917-9","DOIUrl":"10.23736/S2724-5691.25.10917-9","url":null,"abstract":"<p><strong>Background: </strong>Portal hypertension (PH) is a critical condition often managed through surgical interventions such as transjugular intrahepatic portosystemic shunt (TIPS). Conventional portal pressure monitoring relies on invasive measurements, necessitating alternative approaches. Subharmonic-aided pressure estimation (SHAPE) technology offers a noninvasive method utilizing contrast-enhanced ultrasound, potentially reducing procedural risks. This study evaluated the clinical utility of SHAPE in assessing portal hypertension and monitoring hemodynamic changes pre- and post-TIPS placement.</p><p><strong>Methods: </strong>A total of 23 patients with PH underwent direct portal vein pressure (PVP) measurement, and SHAPE was performed for noninvasive estimation. Six patients who underwent TIPS received SHAPE evaluations before and after the procedure. Agreement and correlation between SHAPE and PVP were analyzed.</p><p><strong>Results: </strong>SHAPE demonstrated a strong correlation with PVP (P<0.001), with significant changes observed post-TIPS (P=0.011). These findings suggest SHAPE as a valuable tool for noninvasive monitoring of PH and evaluating TIPS efficacy.</p><p><strong>Conclusions: </strong>SHAPE technology presents a promising noninvasive alternative for assessing portal hypertension in surgical settings. It offers a safer and efficient approach to monitoring hemodynamic changes, particularly in patients undergoing TIPS, potentially reducing reliance on invasive procedures.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"381-384"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences between the Surgical Pleth Index and the RE-SE difference as measures of nociception monitoring under propofol-remifentanil anesthesia.","authors":"Cuicui Jiao, Xiaoping Chen, Jialin Wang, Lin Jin, Xinzhong Chen, Lihong Sun","doi":"10.23736/S2724-5691.25.10885-X","DOIUrl":"10.23736/S2724-5691.25.10885-X","url":null,"abstract":"<p><strong>Background: </strong>To achieve an equilibrium a balance between nociception and antinociception, a suitable depth of anesthesia is essential. The Surgical Pleth Index (SPI) and entropy measurements, which consist of response entropy (RE) and state entropy (SE), serve as tools to assess the level of pain perception during surgical procedures. Research has indicated that the SPI is a more dependable instrument than the RE-SE difference for evaluating pain perception under sevoflurane-remifentanil anesthesia. Nevertheless, the effectiveness of the SPI and RE-SE difference in gauging noxious stimuli under propofol-remifentanil anesthesia is still uncertain. The objective of this study is to compare the sensitivity and dependability of the SPI and RE-SE difference in evaluating noxious stimuli during general anesthesia maintained with propofol and remifentanil.</p><p><strong>Methods: </strong>Thirty patients were administered incremental remifentanil effect-site concentrations (CeREMIs) of 0, 2, and 4 ng/mL under propofol-remifentanil anesthesia. A standardized noxious stimulus was applied for 30 seconds at each CeREMI level. Data regarding changes in the SPI, RE-SE difference difference, RE, SE, heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure were collected for each patient both before and during the stimulus. Receiver operating characteristic curves were analyzed to assess the predictive ability of these indicators for nociceptive stimuli.</p><p><strong>Results: </strong>Under propofol-remifentanil anesthesia, the change in the SPI value gradually decreased in accordance with the CeREMI increase under the same intensity of nociceptive stimulation. Compared with the other indicators, the SPI demonstrated greater reliability in assessing noxious stimulation, exhibiting the highest combination of sensitivity and specificity.</p><p><strong>Conclusions: </strong>In the context of this study, the SPI proved to be a superior indicator compared to the RE-SE difference for monitoring nociception during propofol-remifentanil anesthesia.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"373-380"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of enhanced recovery after surgery in tonsillectomy and adenoidectomy.","authors":"Jingyu Yao, Zhenpeng Liao, Jiaoping Mi, Lukun Yang","doi":"10.23736/S2724-5691.25.10930-1","DOIUrl":"10.23736/S2724-5691.25.10930-1","url":null,"abstract":"<p><strong>Background: </strong>This study was to evaluate the application of ERAS in pediatric patients undergoing tonsillectomy and adenoidectomy.</p><p><strong>Methods: </strong>Sixty patients were randomly divided into ERAS and control group. Patient outcomes, including hospital stay, operation time, bleeding volume, total cost, complications, m-YPAS, FLACC, and RSAS were observed.</p><p><strong>Results: </strong>The length of hospital stay, total cost, and the incidence of postoperative nausea and vomiting in the ERAS group were significantly lower than those in the control group. The RSAS score, m-YPAS and FLACC score of the ERAS group were lower than those of the control group.</p><p><strong>Conclusions: </strong>Our study shows that the application of ERAS can reduce hospital charges and postoperative pain from tonsillectomy and adenoidectomy in children.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"385-392"},"PeriodicalIF":0.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}