Minerva SurgeryPub Date : 2025-12-01Epub Date: 2023-12-21DOI: 10.23736/S2724-5691.23.10187-0
Xiangjuan Liu, Jun Zhao, Jian Li, Yuan Wang, Hongyan Zang
{"title":"The study of tumor regression mode, Ki67 expression and neoadjuvant chemotherapy on prognosis of different molecular breast cancer.","authors":"Xiangjuan Liu, Jun Zhao, Jian Li, Yuan Wang, Hongyan Zang","doi":"10.23736/S2724-5691.23.10187-0","DOIUrl":"10.23736/S2724-5691.23.10187-0","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"502-504"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138831951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01Epub Date: 2025-07-22DOI: 10.23736/S2724-5691.25.10867-8
Wei Liu, Li Jian, Qiquan Zhao
{"title":"Advances in minimally invasive diagnostic techniques for pulmonary diseases.","authors":"Wei Liu, Li Jian, Qiquan Zhao","doi":"10.23736/S2724-5691.25.10867-8","DOIUrl":"10.23736/S2724-5691.25.10867-8","url":null,"abstract":"<p><p>Respiratory disorders can be broadly classified into two primary categories: those triggered by infectious agents and those stemming from noninfectious factors. The infectious group comprises a wide array of pathogens, including bacteria, viruses, and fungi. In contrast, the noninfectious category encompasses conditions such as immune system dysfunctions, as well as both malignant and benign tumors. Given the intricate and diverse nature of these diseases, accurate diagnosis often requires more than just routine clinical assessments and conventional imaging techniques. To address this complexity, the medical community has increasingly turned to minimally invasive diagnostic methods, which provide enhanced precision in managing complex cases. This comprehensive review delves into the utilization of these cutting-edge minimally invasive technologies within the field of respiratory medicine. It meticulously outlines their current applications, highlights their benefits and limitations, and also explores potential directions for future research endeavors, aiming to shed light on the evolving landscape of respiratory disease diagnosis and management.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"468-478"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01Epub Date: 2025-09-12DOI: 10.23736/S2724-5691.25.10942-8
Tiziana Marchese, Valentina Valle, Stefano D'Ugo, Erika Delos, Norma Depalma, Annarita Libia, Farshad Manoochehri, William Sergi, Marcello G Spampinato
{"title":"Inframesocolic pancreatic anastomosis after pancreatoduodenectomy: description and initial experience with a novel technique.","authors":"Tiziana Marchese, Valentina Valle, Stefano D'Ugo, Erika Delos, Norma Depalma, Annarita Libia, Farshad Manoochehri, William Sergi, Marcello G Spampinato","doi":"10.23736/S2724-5691.25.10942-8","DOIUrl":"10.23736/S2724-5691.25.10942-8","url":null,"abstract":"<p><strong>Background: </strong>Pancreatoduodenectomy (PD) is one of the most challenging surgical procedures among abdominal surgeries. The most common complication after PD is postoperative pancreatic fistula (POPF), which can be severe and entail other complications, such as post-pancreatectomy hemorrhage (PPH), which can be fatal. Several surgical techniques have been proposed to reduce the incidence of POPF and PPH.</p><p><strong>Methods: </strong>In this study, we describe inframesocolic pancreatic anastomosis, which involves segregating the pancreatic anastomosis into the inframesocolic area by mobilizing the pancreatic remnant and creating a small window into the transverse mesocolon.</p><p><strong>Results: </strong>This surgical technique was performed in 17 patients, with promising results in terms of delayed PPH prevention. In particular, we had only one case of PPH that was successfully treated by placing a stent into the SMA. No other bleeding events were reported, even in cases of anastomotic leakage.</p><p><strong>Conclusions: </strong>In the context of mitigation strategies, this technique might be efficient in reducing the incidence of delayed PPH due to leakage of pancreatic juice into the supramesocolic area and consequent vascular erosion.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"423-430"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01DOI: 10.23736/S2724-5691.25.10981-7
Jun Chen, Rushan Fei, Feixia Wang, Weizhen Li, Hanju Hua
{"title":"Pressure-controlled tube ileostomy after lower anterior resection of rectal cancer: a new type of protective stoma in rectal anastomosis.","authors":"Jun Chen, Rushan Fei, Feixia Wang, Weizhen Li, Hanju Hua","doi":"10.23736/S2724-5691.25.10981-7","DOIUrl":"10.23736/S2724-5691.25.10981-7","url":null,"abstract":"<p><strong>Background: </strong>Tube ileostomy can prevent anastomotic leakage (AL) on the patients underwent lower anterior resection. However, it has one major disadvantage: the inability to control fecal diversion efficacy (FDE). In this single-center, prospective randomized controlled trial (RCT), we evaluated a novel technique, pressure-controlled tube ileostomy (PCTI), which uses cuff-pressure adjustment to maintain reliable FDE, and assessed its safety and effectiveness.</p><p><strong>Methods: </strong>This study was conducted as a single-center prospective RCT. Patients were randomly allocated (1:1) to PCTI or LI (Ll) using a computer-generated sequence with allocation concealment via sealed opaque envelopes; blinding of surgeons/patients was not feasible.</p><p><strong>Results: </strong>Baseline characteristics were comparable between groups. The anastomotic leakage rates were 9.2% (23/250) in the PCTI group and 9.7% (24/248) in the LI group received the initial surgery (P=0.85). The rates of stoma-related complications including infections, irritant dermatitis, herniation and so on, were 8.8% in PCTI group and 16.2% in LI group (P=0.0133), respectively. Fifteen patients received LI retained their stoma, compared with 2 in the PCTI group (P=0.0013). In PCTI group, the time of cannula extubation and stoma closure after cannula extubation were 20.5±4.6 and 7.2±4.4 days, respectively.</p><p><strong>Conclusions: </strong>The PCTI can effectively inhibit the occurrence of grade C anastomotic leakage and reduce the occurrence of serious complications caused by anastomotic leakage through the FDE control by adjusting the cuff pressure and can avoid secondary reversal surgery. We consider that the improved PCTI is a safe and practical-surgical technique in protecting the anastomosis.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 6","pages":"442-451"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01Epub Date: 2023-11-28DOI: 10.23736/S2724-5691.23.10051-7
Xiangyi Cao, Yi Zhang
{"title":"Progress in the treatment and pregnancy of precancerous lesions and borderline tumors of reproductive system in pregnant women.","authors":"Xiangyi Cao, Yi Zhang","doi":"10.23736/S2724-5691.23.10051-7","DOIUrl":"10.23736/S2724-5691.23.10051-7","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"506-508"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01Epub Date: 2024-03-04DOI: 10.23736/S2724-5691.23.10177-8
Jian L Guo
{"title":"Clinical application of nursing risk management in nursing management of surgical patients.","authors":"Jian L Guo","doi":"10.23736/S2724-5691.23.10177-8","DOIUrl":"10.23736/S2724-5691.23.10177-8","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"500-502"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"External application of chicken eggs on delayed healing of tendon bone in mice with rotator cuff injury.","authors":"Xingxing Zhang, Hao Ren, Chuankai Shi, Xian-Pei Wang, Qing Zhang, Ming Xiang","doi":"10.23736/S2724-5691.23.10016-5","DOIUrl":"10.23736/S2724-5691.23.10016-5","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"497-498"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01Epub Date: 2024-03-13DOI: 10.23736/S2724-5691.23.10015-3
Jianghong Zhou, Fangjiang Zheng, Jing Chen, Tao Chen, Juan Wang, Xiaoyan Peng, Zhanping Jing, Fujuan Wang, Haijun Li
{"title":"Effect of acupoint conditioning nursing technology based on holistic view of traditional Chinese medicine on cancer-related fatigue of patients with lung cancer after chemotherapy.","authors":"Jianghong Zhou, Fangjiang Zheng, Jing Chen, Tao Chen, Juan Wang, Xiaoyan Peng, Zhanping Jing, Fujuan Wang, Haijun Li","doi":"10.23736/S2724-5691.23.10015-3","DOIUrl":"10.23736/S2724-5691.23.10015-3","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"495-496"},"PeriodicalIF":0.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01DOI: 10.23736/S2724-5691.25.11028-9
Yonatan Lessing, Tal Inbar-Weissman, Ron Cohen, Nir Messer, Orr Erlich-Feingold, Fahim Kanani, Guy Lahat, Lior Orbach
{"title":"Comparing palliative gastrectomy and gastrojejunostomy for advanced gastric cancer: impact on survival and postoperative outcomes.","authors":"Yonatan Lessing, Tal Inbar-Weissman, Ron Cohen, Nir Messer, Orr Erlich-Feingold, Fahim Kanani, Guy Lahat, Lior Orbach","doi":"10.23736/S2724-5691.25.11028-9","DOIUrl":"10.23736/S2724-5691.25.11028-9","url":null,"abstract":"<p><strong>Background: </strong>Palliative surgical management of advanced gastric cancer with gastric outlet obstruction remains controversial. While both palliative gastrectomy (PG) and gastrojejunostomy (PGJ) offer symptom relief, their impact on survival and postoperative outcomes is debated.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of 70 patients with advanced gastric cancer and symptomatic gastric outlet obstruction, treated at a single tertiary center between 2017 and 2024. Patients underwent either PG or PGJ after being deemed unsuitable for endoscopic intervention. Clinical and surgical parameters, complications, nutritional support, and survival outcomes were analyzed.</p><p><strong>Results: </strong>Of the 70 patients, 46 underwent PG and 24 underwent PGJ. Median survival was significantly longer in the PG group (344 vs. 117 days, P<0.001), and PG was an independent predictor of improved survival (HR 0.083, P<0.001). PG was associated with higher rates of anastomotic leaks and ICU admissions, while PGJ showed higher rates of delayed gastric emptying and need for post-discharge nutritional support (33.3% vs. 6.7%, P=0.009). Return to oral intake was more common after PG (95.7% vs. 79.2%, P=0.042). Postoperative chemotherapy significantly improved survival (HR=0.152, P=0.003).</p><p><strong>Conclusions: </strong>PG offers a significant survival benefit over PGJ in selected patients with advanced gastric cancer, but at the cost of increased surgical morbidity. Careful patient selection based on disease extent, performance status, and likelihood of postoperative recovery is essential for optimizing outcomes.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 6","pages":"452-460"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva SurgeryPub Date : 2025-12-01DOI: 10.23736/S2724-5691.25.11037-X
Robert M O'Connell, David Moloney, Fiona Hand, Tom Gallagher, Emir Hoti
{"title":"Acute cholecystitis in older adults: a national registry-based study of patient outcomes.","authors":"Robert M O'Connell, David Moloney, Fiona Hand, Tom Gallagher, Emir Hoti","doi":"10.23736/S2724-5691.25.11037-X","DOIUrl":"10.23736/S2724-5691.25.11037-X","url":null,"abstract":"<p><strong>Background: </strong>Acute cholecystitis (AC) is a common general surgical emergency. Older age is associated with higher incidence of gallstones and increasing severity of AC. Data on outcomes for older adults with AC remain sparse however.</p><p><strong>Methods: </strong>All patients with AC presenting to public hospitals in Ireland between January 2017 and July 2023 were identified using the National Quality Assurance and Improvement System (NQAIS). Data were collected on patient demographics, comorbidities, length of stay, clinical management, in-patient mortality, and readmissions. Patients were grouped into cohorts by age range.</p><p><strong>Results: </strong>Overall, 20,886 admission episodes were identified, with a median age of 59 years (IQR 43-73) and 11,747 (56%) female patients; 3745 patients were in the 65-74 year group, 3239 in the 75-84 year, and 1478 in the over 85 year group. Older adults had more co-morbidities (Charlson Co-morbidity Index >3 in 440 (30%) of the over 85s, 689 (21%) of 75-84 years, 429 (11%) 65-74 years, and 421 (3%) under 65s (P<0.0001). In the over 85 years group, patients had the highest in-patient mortality rate (96 [6.5%]; P<0.0001), lowest rate of cholecystectomy (49 [3%]; P<0.0001), highest rate of percutaneous cholecystostomy use (140 [9%]; P<0.0001), and lowest rates of discharge to home (947 [64%]). Patients in the 65-74 year and 75-84 year groups also experienced poorer outcomes than those in the under 65 year group.</p><p><strong>Conclusions: </strong>Increasing age is associated with worsening outcomes for patients with AC. For the oldest adults, AC is associated with significant risks of morbidity and potential loss of independence.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 6","pages":"461-467"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}