Minerva Surgery最新文献

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Treatment of acute pancreatitis. 急性胰腺炎的治疗。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-06-01 Epub Date: 2025-05-22 DOI: 10.23736/S2724-5691.25.10773-9
Guido Basile, Marco Vacante, Antonino Corsaro, Francesco R Evola, Grazia Maugeri, Martina Barchitta, Antonio Biondi, Giuseppe Musumeci, Velia D'Agata, Giuseppe Evola
{"title":"Treatment of acute pancreatitis.","authors":"Guido Basile, Marco Vacante, Antonino Corsaro, Francesco R Evola, Grazia Maugeri, Martina Barchitta, Antonio Biondi, Giuseppe Musumeci, Velia D'Agata, Giuseppe Evola","doi":"10.23736/S2724-5691.25.10773-9","DOIUrl":"10.23736/S2724-5691.25.10773-9","url":null,"abstract":"<p><p>Acute pancreatitis (AP) is a potentially life-threatening inflammatory condition characterized by localized pancreatic damage and the activation of the inflammatory cascade, leading to systemic inflammatory response syndrome (SIRS). This complex disease often presents with a variable and unpredictable course. The primary causes of AP include the migration of gallstones and alcohol consumption. The Revised Atlanta Classification 2012 (RAC) is the most widely utilized classification system for AP, distinguishing between interstitial edematous pancreatitis and necrotizing pancreatitis, three severity levels and an early and a late phase. Severe AP carries a high risk of mortality. Currently, there is no definitive prognostic score for accurately predicting severe cases of AP. Initial management focuses on supportive care, applicable to both mild and severe forms of the disease, while later management addresses complications associated with severe AP. Although there is no consensus on the optimal type or regimen of fluids for resuscitation, goal-directed fluid therapy, particularly with Ringer's lactate, has been linked to improved outcomes. Prophylactic antibiotics have not proven effective in preventing infectious complications associated with AP. Patients experiencing mild acute gallstone pancreatitis should be advised to undergo laparoscopic cholecystectomy during their initial admission, whereas those with severe gallstone pancreatitis and signs of cholangitis or choledocholithiasis may benefit from early endoscopic retrograde cholangiopancreatography (ERCP). The management of severe AP complications has evolved from an early surgical approach to a minimally invasive step-up strategy, which is now considered the standard intervention.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"236-257"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation on the current situation and influencing factors of the knowledge and practice of nurses in operating room for prevention of central venous catheter-related bloodstream infection. 手术室护士预防中心静脉置管相关血流感染知识与实践现状及影响因素调查
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-06-01 Epub Date: 2025-02-26 DOI: 10.23736/S2724-5691.25.10697-7
Mayi Yang, Liping Ye, Chunlei Li, Zhe Wang, Xiaofeng He, Yan Hu
{"title":"Investigation on the current situation and influencing factors of the knowledge and practice of nurses in operating room for prevention of central venous catheter-related bloodstream infection.","authors":"Mayi Yang, Liping Ye, Chunlei Li, Zhe Wang, Xiaofeng He, Yan Hu","doi":"10.23736/S2724-5691.25.10697-7","DOIUrl":"10.23736/S2724-5691.25.10697-7","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"288-291"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First world-wide report of robotic splenectomy with the novel Hugo™ RAS for cellular myofibroma of the spleen. 全球首例使用新型Hugo™RAS机器人脾切除术治疗脾细胞肌纤维瘤的报道。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-06-01 DOI: 10.23736/S2724-5691.25.10869-1
Antonio Gangemi, Andrea Laurenzi, Anthony P Lisi, Matteo Cescon
{"title":"First world-wide report of robotic splenectomy with the novel Hugo™ RAS for cellular myofibroma of the spleen.","authors":"Antonio Gangemi, Andrea Laurenzi, Anthony P Lisi, Matteo Cescon","doi":"10.23736/S2724-5691.25.10869-1","DOIUrl":"https://doi.org/10.23736/S2724-5691.25.10869-1","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 3","pages":"282-283"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TIVAD implantation for chemotherapy: retrospective comparison between US-guided vein puncture vs. surgical vein cutdown on more than 3000 procedures. 用于化疗的TIVAD植入:回顾性比较美国引导静脉穿刺与手术静脉切断在3000多个程序。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-06-01 Epub Date: 2025-05-22 DOI: 10.23736/S2724-5691.25.10823-X
Alessia Fassari, Alessandra Micalizzi, Francesco De Angelis, Diletta Di Meo, Marianna Timeo, Lorenzo Svolacchia, Sergio Gazzanelli, Angelo Iossa, Simone Sibio, Giulio Lelli, Giuseppe Cavallaro
{"title":"TIVAD implantation for chemotherapy: retrospective comparison between US-guided vein puncture vs. surgical vein cutdown on more than 3000 procedures.","authors":"Alessia Fassari, Alessandra Micalizzi, Francesco De Angelis, Diletta Di Meo, Marianna Timeo, Lorenzo Svolacchia, Sergio Gazzanelli, Angelo Iossa, Simone Sibio, Giulio Lelli, Giuseppe Cavallaro","doi":"10.23736/S2724-5691.25.10823-X","DOIUrl":"10.23736/S2724-5691.25.10823-X","url":null,"abstract":"<p><strong>Background: </strong>Totally implantable venous access devices (TIVADs) are widely used for long-term therapies, including chemotherapy. Given the potential for serious complications, it is crucial to determine the safest implantation technique with the lowest risk profile. This bicentric, retrospective study aims to compare the surgical vein cut-down approach with ultrasound-guided percutaneous vein puncture in terms of procedural success, complication rates, and operative efficiency.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 3373 patients who underwent TIVAD implantation at two centers. Patients were divided into two groups: group A (N.=1846) underwent TIVAD placement via cephalic or external jugular vein cut-down, while group B (N.=1527) underwent ultrasound-guided puncture of the internal jugular or subclavian vein. The two techniques were compared based on operative time, success rate, need for conversion, and complication incidence.</p><p><strong>Results: </strong>In Group A, the cephalic vein was used in 1733 cases, while the external jugular vein was used in 133 cases. No conversions to percutaneous access or contralateral approaches were required. In group B, TIVADs were implanted via the subclavian vein in 1490 patients and the internal jugular vein in 172 patients. The mean operative time was comparable between the two groups (32.6±11.3 minutes in group A vs. 34.2±12.5 minutes in group B; P not significant). However, the 30-day complication rate was significantly lower in group A (3.8%) compared to group B (5.7%; P<0.05).</p><p><strong>Conclusions: </strong>This bicentric retrospective study suggests that the surgical cut-down approach for TIVAD implantation via peripheral veins is associated with a high success rate and a lower short-term complication rate compared to percutaneous techniques. However, given the retrospective design and potential center-specific factors, further prospective, multicentric studies are needed to confirm these findings and determine the optimal approach in different clinical settings.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"224-230"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Day surgery for rhegmatogenous retinal detachment: analyzing complications, long-term outcomes, and recurrence rates. 孔源性视网膜脱离的日间手术:分析并发症,长期结果和复发率。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-05-22 DOI: 10.23736/S2724-5691.25.10829-0
Juanying Li, Wenfang Zhang
{"title":"Day surgery for rhegmatogenous retinal detachment: analyzing complications, long-term outcomes, and recurrence rates.","authors":"Juanying Li, Wenfang Zhang","doi":"10.23736/S2724-5691.25.10829-0","DOIUrl":"https://doi.org/10.23736/S2724-5691.25.10829-0","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The application value of dynamic arterial elasticity in improving hemodynamic changes during fluid resuscitation in shock patients. 动态动脉弹性在改善休克患者液体复苏过程中血流动力学变化中的应用价值。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-04-01 Epub Date: 2023-11-21 DOI: 10.23736/S2724-5691.23.10105-5
Leiming Xu, Xin Wang, Bo Pu, Suhui Li, Lan Wang, Lulu Zhang, Yong Li
{"title":"The application value of dynamic arterial elasticity in improving hemodynamic changes during fluid resuscitation in shock patients.","authors":"Leiming Xu, Xin Wang, Bo Pu, Suhui Li, Lan Wang, Lulu Zhang, Yong Li","doi":"10.23736/S2724-5691.23.10105-5","DOIUrl":"10.23736/S2724-5691.23.10105-5","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"200-202"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138177478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The American College of Surgeon National Surgical Quality Improvement Program risk calculator does not predict individual outcomes in an elderly Italian population. 美国外科医生学会国家外科质量改进计划风险计算器无法预测意大利老年人群的个体结果。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-04-01 Epub Date: 2025-03-19 DOI: 10.23736/S2724-5691.25.10714-4
Stefano Siboni, Pietro Fusella, Pamela Milito, Roberta De Maron, Francesca Senzani, Alessandro Meloni, Maria T Cuppone, Daniele Bernardi, Marco Sozzi, Emanuele L Asti
{"title":"The American College of Surgeon National Surgical Quality Improvement Program risk calculator does not predict individual outcomes in an elderly Italian population.","authors":"Stefano Siboni, Pietro Fusella, Pamela Milito, Roberta De Maron, Francesca Senzani, Alessandro Meloni, Maria T Cuppone, Daniele Bernardi, Marco Sozzi, Emanuele L Asti","doi":"10.23736/S2724-5691.25.10714-4","DOIUrl":"10.23736/S2724-5691.25.10714-4","url":null,"abstract":"<p><strong>Background: </strong>Elderly population has an increased risk of post-operative complications, therefore a precise and quick assessment of the expected risks allows a more aware decision on surgical indications. The American College of Surgeons NSQIP Surgical Risk Calculator (ACS-NSQIP SRC) is a practical tool that provides estimates of outcomes, however previous studies showed heterogeneous results. Our aim was to test its ability to correctly predict post-operative complications in a cohort of elderly patients who underwent major surgery in our Institution.</p><p><strong>Methods: </strong>Data on consecutive elderly patients (≥75 years) that underwent major surgery (2022-2023) were retrospectively collected. The SRC was queried and the risk of post-operative complications, including geriatric outcomes, was obtained. Patients were divided into four groups based on CPT code. Observed and expected complication rates were compared.</p><p><strong>Results: </strong>A total of 112 patients (50.9% female, median age 80 years, median BMI 28.8 kg/m<sup>2</sup>) were included and divided into groups (urgent 60 patients, colorectal 20, upper-GI resections 17 and benign upper-GI 15). In the urgent group, we observed a higher rate of serious complications (22 vs. 12.7, P=0.005), any complications (30 vs. 15.6, P<0.001) and superficial SSI (17 vs. 4.9, P<0.001) than the expected. Discharge to post-acute care facilities was over-estimated.</p><p><strong>Conclusions: </strong>The ACS-NSQIP SRC demonstrated poor ability to predict post-operative complications and geriatric outcomes in our cohort of elderly patients. Our findings confirm other studies that temper the enthusiasm towards the NSQIP SRC as a practical tool to predict post-operative complications, especially in an urgent setting.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"107-114"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic parastomal hernia repair: an updated systematic review. 机器人造口旁疝修复:最新的系统综述。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-04-01 Epub Date: 2025-03-07 DOI: 10.23736/S2724-5691.25.10777-6
Tommaso Violante, Richard Sassun, Davide Ferrari, Annaclara Sileo, Robert R Cima
{"title":"Robotic parastomal hernia repair: an updated systematic review.","authors":"Tommaso Violante, Richard Sassun, Davide Ferrari, Annaclara Sileo, Robert R Cima","doi":"10.23736/S2724-5691.25.10777-6","DOIUrl":"10.23736/S2724-5691.25.10777-6","url":null,"abstract":"<p><strong>Introduction: </strong>Parastomal hernias (PSH) are a frequent complication following ostomy surgery, often requiring surgical intervention. Robotic surgery offers potential advantages in PSH repair, but evidence on its efficacy remains limited. This systematic review evaluates the outcomes of different robotic PSH repair techniques.</p><p><strong>Evidence acquisition: </strong>A systematic search of PubMed, Embase, and Cochrane databases was conducted (2015-2024) to identify studies on robotic PSH repair. Fourteen studies (13 retrospective, two prospective) met the inclusion criteria after screening 324 articles.</p><p><strong>Evidence synthesis: </strong>Data on patient demographics, surgical techniques, complications, recurrence rates, and follow-up duration were extracted. The analysis included 355 patients with a median follow-up of 12 months. Early studies focused on feasibility and safety, with subsequent research refining specific techniques like the Sugarbaker, Pauli, and keyhole repairs. Reported recurrence rates ranged from 0% to 9.5% across these techniques. However, 30-day complication rates varied significantly (0% to 50%), highlighting the need for standardized reporting and patient selection criteria. While some studies demonstrated low recurrence rates with acceptable complication profiles, others revealed higher complication rates, potentially related to specific techniques or patient factors. The emergence of variations within the Sugarbaker technique, such as the retromuscular approach with transversus abdominis release (TAR), demonstrates ongoing innovation in robotic PSH repair.</p><p><strong>Conclusions: </strong>Robotic PSH repair shows promise, but further research is needed to confirm its long-term efficacy and cost-effectiveness.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"160-164"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of laparoscopic cholecystectomy vs. non-invasive gallstone dissolution to manage cholelithiasis: clinical outcomes and quality of life. 腹腔镜胆囊切除术与非侵入性胆结石溶解治疗胆石症的疗效:临床结果和生活质量。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-04-01 DOI: 10.23736/S2724-5691.25.10833-2
Jingxin Zhang, Ming Ma, Jinlong Tian, Shanshan Yang, Yixiang Zhang, Danqi Zhang
{"title":"The efficacy of laparoscopic cholecystectomy vs. non-invasive gallstone dissolution to manage cholelithiasis: clinical outcomes and quality of life.","authors":"Jingxin Zhang, Ming Ma, Jinlong Tian, Shanshan Yang, Yixiang Zhang, Danqi Zhang","doi":"10.23736/S2724-5691.25.10833-2","DOIUrl":"https://doi.org/10.23736/S2724-5691.25.10833-2","url":null,"abstract":"<p><strong>Background: </strong>This retrospective study aims to compare the clinical efficacy and impact on the quality of life of laparoscopic cholecystectomy with medication dissolution of gallstones.</p><p><strong>Methods: </strong>Clinical data of 86 cholelithiasis patients admitted to our hospital from January 2021 to December 2022 were retrospectively analyzed. The patients were divided into a conservative group of 40 cases and a surgical group of 46 cases based on different treatment methods. The conservative group received ursodeoxycholic acid combined with compound cholecystokinetic granules for gallstone dissolution, while the surgical group underwent laparoscopic cholecystectomy. The clinical efficacy, recovery indicators, complications, pre- and post-treatment Short-Form 36 Health Survey (SF-36) scores, and recurrence rates were observed.</p><p><strong>Results: </strong>In the surgical group, the total effective rate was higher, the time to symptom relief and length of hospital stay were shorter, but the hospitalization costs were higher than conservative group. The incidences of complications and the recurrence rate were lower in the surgical group than in the conservative group. However, the SF-36 scores for post-treatment physiological function, physical role function, bodily pain, vitality, and general health were higher in the surgical group than in the conservative group.</p><p><strong>Conclusions: </strong>Compared to medication dissolution, laparoscopic cholecystectomy demonstrates superior efficacy in the treatment of cholelithiasis, promoting symptom relief, reducing hospitalization duration, decreasing the incidence of complications, improving quality of life, lowering recurrence rates, and therefore deserves wider clinical application.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":"80 2","pages":"131-137"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical evidence and rationale of topical nifedipine and lidocaine ointment in the treatment of anal fissure and hemorrhoidal disease. 外用硝苯地平利多卡因软膏治疗肛裂和痔疮的临床依据和原理。
IF 1.8 4区 医学
Minerva Surgery Pub Date : 2025-04-01 Epub Date: 2025-02-13 DOI: 10.23736/S2724-5691.25.10771-5
Gaetano Gallo, Mario Trompetto
{"title":"Clinical evidence and rationale of topical nifedipine and lidocaine ointment in the treatment of anal fissure and hemorrhoidal disease.","authors":"Gaetano Gallo, Mario Trompetto","doi":"10.23736/S2724-5691.25.10771-5","DOIUrl":"10.23736/S2724-5691.25.10771-5","url":null,"abstract":"<p><strong>Introduction: </strong>Anorectal conditions such as hemorrhoidal disease and anal fissure are frequently painful and debilitating. Pain after hemorrhoidectomy is also common and distressing. These conditions are at least initially managed conservatively. An ointment formulation containing the calcium channel blocker nifedipine and the local anesthetic lidocaine has an established role in the treatment of rectal conditions, particularly conditions associated with anal sphincter hypertonia such as hemorrhoidal disease and anal fissure. This review aimed to compile the evidence for the use of nifedipine 0.3% and lidocaine 1.5% ointment in treating these common but bothersome anorectal diseases.</p><p><strong>Evidence acquisition: </strong>A comprehensive literature search was conducted, updated to 07 August 2024, using PubMed and MEDLINE databases to identify studies of lidocaine and nifedipine, alone or in combination, for the topical treatment of anal fissure or hemorrhoidal disease. Articles identified in the literature search were supplemented by ad hoc searches and supplemented by relevant literature known to the authors.</p><p><strong>Evidence synthesis: </strong>Nifedipine 0.3% and lidocaine 1.5% ointment is effective in relieving pain and aiding the resolution of thrombosed hemorrhoids, reducing resting anal pressure and healing chronic anal fissures, and controlling pain after hemorrhoidectomy. The ointment was significantly better than controls consisting of topical lidocaine 1.5% alone or in combination with hydrocortisone acetate 1%.</p><p><strong>Conclusions: </strong>Although the available literature on the topical application of nifedipine and lidocaine in anorectal diseases is limited, nifedipine 0.3% and lidocaine 1.5% ointment should be considered a valid treatment option for clinicians treating anorectal diseases. Further studies are warranted to confirm and extend the results reported.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":" ","pages":"177-192"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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