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Minerva Biotechnology and Biomolecular Research最新文献

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Lack of plasma viremia in SARS-CoV-2 seropositive blood donors carrying the virus in nasopharyngeal swabs argues against potential transmission of COVID-19 through blood 在鼻咽拭子中携带该病毒的SARS-CoV-2血清阳性献血者中没有血浆病毒血症，这证明了COVID-19可能通过血液传播
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-03-01 DOI: 10.23736/s2724-542x.21.02840-6
J. R. Fiore, M. Di Stefano, M. R. Lipsi, F. Antonucci, Tommaso Granato, G. Faleo, S. Bruno, F. Arena, M. Margaglione, M. Centra
{"title":"Lack of plasma viremia in SARS-CoV-2 seropositive blood donors carrying the virus in nasopharyngeal swabs argues against potential transmission of COVID-19 through blood","authors":"J. R. Fiore, M. Di Stefano, M. R. Lipsi, F. Antonucci, Tommaso Granato, G. Faleo, S. Bruno, F. Arena, M. Margaglione, M. Centra","doi":"10.23736/s2724-542x.21.02840-6","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02840-6","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79930955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Estimation of maximum recommended therapeutic dose of anti-retroviral drugs using diversified sampling and varied descriptors 利用多样化采样和不同描述符估计抗逆转录病毒药物的最大推荐治疗剂量
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.20.02669-5
Roopshikha Sahu, Amisha Yadav, A. Nath
{"title":"Estimation of maximum recommended therapeutic dose of anti-retroviral drugs using diversified sampling and varied descriptors","authors":"Roopshikha Sahu, Amisha Yadav, A. Nath","doi":"10.23736/s2724-542x.20.02669-5","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02669-5","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82842410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ADAM17 inhibition effects on Mer shedding ADAM17对Mer脱落的抑制作用
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.20.02734-2
L. Salmi, F. Patrucco, L. Molinari, M. Bellan, P. Sainaghi, L. Castello
{"title":"ADAM17 inhibition effects on Mer shedding","authors":"L. Salmi, F. Patrucco, L. Molinari, M. Bellan, P. Sainaghi, L. Castello","doi":"10.23736/s2724-542x.20.02734-2","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02734-2","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72408049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The immunomodulation of osteoblasts and chondroblasts differentiated from programmed death-ligand 1-positive mesenchymal stem cells 程序性死亡配体1阳性间充质干细胞分化成骨细胞和成软骨细胞的免疫调节
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.21.02753-1
N. Vu, T. T. Dao, N. Truong, H. Nguyen, P. Pham
{"title":"The immunomodulation of osteoblasts and chondroblasts differentiated from programmed death-ligand 1-positive mesenchymal stem cells","authors":"N. Vu, T. T. Dao, N. Truong, H. Nguyen, P. Pham","doi":"10.23736/s2724-542x.21.02753-1","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02753-1","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84121972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of medicinal transdermal patch impregnated with silver nanoparticles synthesized from biomedical photographic wastes 利用生物医学摄影废弃物合成银纳米粒子浸渍药用透皮贴片的制备
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.20.02642-7
T. R. Poorani, Selvam Iswarya, M. Priya, Sri D. Sivakumar, S. Kannan
{"title":"Fabrication of medicinal transdermal patch impregnated with silver nanoparticles synthesized from biomedical photographic wastes","authors":"T. R. Poorani, Selvam Iswarya, M. Priya, Sri D. Sivakumar, S. Kannan","doi":"10.23736/s2724-542x.20.02642-7","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02642-7","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82956870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pharmacogenetic study in HIV-infected patients treated with ritonavir: hematological and cardiovascular disease risk analysis 利托那韦治疗hiv感染患者的药物遗传学研究:血液学和心血管疾病风险分析
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.20.02739-1
J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio
{"title":"A pharmacogenetic study in HIV-infected patients treated with ritonavir: hematological and cardiovascular disease risk analysis","authors":"J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio","doi":"10.23736/s2724-542x.20.02739-1","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02739-1","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85755006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of brain-spinal cord-heart circuit and its dermatologic antenna in imaging 脑脊髓-心回路及其皮肤学天线在影像学中的作用
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02633-6
M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti
{"title":"The role of brain-spinal cord-heart circuit and its dermatologic antenna in imaging","authors":"M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti","doi":"10.23736/s2724-542x.20.02633-6","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02633-6","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86178673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental biology of Corona vaccine: lipid nanoparticle mRNA-encapsulation, a safe approach 冠状病毒疫苗的发育生物学:脂质纳米粒mrna包封，一种安全的方法
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/S2724-542X.21.02742-7
S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick
{"title":"Developmental biology of Corona vaccine: lipid nanoparticle mRNA-encapsulation, a safe approach","authors":"S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick","doi":"10.23736/S2724-542X.21.02742-7","DOIUrl":"https://doi.org/10.23736/S2724-542X.21.02742-7","url":null,"abstract":"The global pandemic of COVID-19 is progressing rapidly across the world and declared as health emergency. The novel Coronavirus can cause severe lower respiratory tract infections primarily in geriatric, immunocompromised persons, infants and patients with comorbidities, or genetic disorders. Few Emergency Use Authorizations (EAUs) have been granted by FDA and other regulatory bodies with an aim to repurpose the existing approved medicines to fight the disease, and till date no specific treatment methodologies or preventive measures are available. At present, numerous medications which are already approved for other therapeutic indications, as well as the new medications, are undergoing clinical trials for the evaluation of safety and efficacy against COVID-19 infection. These therapeutic ranges include antimalarial, antiviral, steroids, convalescent plasma containing antibodies, and immune modulators, etc. Nevertheless, the primary focus is on preventive care and currently more than hundred potential vaccine candidates are under development by leading biotech companies across the globe which are at different phases of clinical development. Lipid based mRNA delivery, DNA delivery and mAbs are the most advanced technologies being embraced besides whole-virion inactivated vaccine, attenuated live vaccine, non-replicating viral vector-based vaccine, protein single unit vaccine and multiunit vaccine. This review focuses on the current progress in drug delivery systems of COVID-19 vaccine across industries, academics, and government funded research institutes with a special focus on the synthetic mRNA-based lipid nanoparticle (LNP).","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85345655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diallyl disulfide regulates proliferation, apoptosis and aerobic glycolysis by down-regulating PKM2 in gastric cancer cells 二烯丙基二硫醚通过下调PKM2调控胃癌细胞增殖、凋亡和有氧糖酵解
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02634-8
Zhiyan Li, Baiwei Zhao, Deyao Zhang, J. Deng, Yongming Chen, Jian Zhou
{"title":"Diallyl disulfide regulates proliferation, apoptosis and aerobic glycolysis by down-regulating PKM2 in gastric cancer cells","authors":"Zhiyan Li, Baiwei Zhao, Deyao Zhang, J. Deng, Yongming Chen, Jian Zhou","doi":"10.23736/s2724-542x.20.02634-8","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02634-8","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75072071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple biomarker panel for the detection of circulating tumor cells in peripheral blood of breast cancer patients for early detection using the real-time reverse transcription-polymerase chain reaction 采用实时逆转录-聚合酶链式反应检测乳腺癌患者外周血循环肿瘤细胞的多种生物标志物面板，用于早期检测
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02645-2
Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar
{"title":"Multiple biomarker panel for the detection of circulating tumor cells in peripheral blood of breast cancer patients for early detection using the real-time reverse transcription-polymerase chain reaction","authors":"Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar","doi":"10.23736/s2724-542x.20.02645-2","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02645-2","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80002552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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