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Minerva Biotechnology and Biomolecular Research最新文献

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A pharmacogenetic study in HIV-infected patients treated with ritonavir: hematological and cardiovascular disease risk analysis 利托那韦治疗hiv感染患者的药物遗传学研究:血液学和心血管疾病风险分析
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2022-01-01 DOI: 10.23736/s2724-542x.20.02739-1
J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio
{"title":"A pharmacogenetic study in HIV-infected patients treated with ritonavir: hematological and cardiovascular disease risk analysis","authors":"J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio","doi":"10.23736/s2724-542x.20.02739-1","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02739-1","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"57 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85755006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of brain-spinal cord-heart circuit and its dermatologic antenna in imaging 脑脊髓-心回路及其皮肤学天线在影像学中的作用
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02633-6
M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti
{"title":"The role of brain-spinal cord-heart circuit and its dermatologic antenna in imaging","authors":"M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti","doi":"10.23736/s2724-542x.20.02633-6","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02633-6","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"78 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86178673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental biology of Corona vaccine: lipid nanoparticle mRNA-encapsulation, a safe approach 冠状病毒疫苗的发育生物学:脂质纳米粒mrna包封，一种安全的方法
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/S2724-542X.21.02742-7
S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick
{"title":"Developmental biology of Corona vaccine: lipid nanoparticle mRNA-encapsulation, a safe approach","authors":"S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick","doi":"10.23736/S2724-542X.21.02742-7","DOIUrl":"https://doi.org/10.23736/S2724-542X.21.02742-7","url":null,"abstract":"The global pandemic of COVID-19 is progressing rapidly across the world and declared as health emergency. The novel Coronavirus can cause severe lower respiratory tract infections primarily in geriatric, immunocompromised persons, infants and patients with comorbidities, or genetic disorders. Few Emergency Use Authorizations (EAUs) have been granted by FDA and other regulatory bodies with an aim to repurpose the existing approved medicines to fight the disease, and till date no specific treatment methodologies or preventive measures are available. At present, numerous medications which are already approved for other therapeutic indications, as well as the new medications, are undergoing clinical trials for the evaluation of safety and efficacy against COVID-19 infection. These therapeutic ranges include antimalarial, antiviral, steroids, convalescent plasma containing antibodies, and immune modulators, etc. Nevertheless, the primary focus is on preventive care and currently more than hundred potential vaccine candidates are under development by leading biotech companies across the globe which are at different phases of clinical development. Lipid based mRNA delivery, DNA delivery and mAbs are the most advanced technologies being embraced besides whole-virion inactivated vaccine, attenuated live vaccine, non-replicating viral vector-based vaccine, protein single unit vaccine and multiunit vaccine. This review focuses on the current progress in drug delivery systems of COVID-19 vaccine across industries, academics, and government funded research institutes with a special focus on the synthetic mRNA-based lipid nanoparticle (LNP).","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85345655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diallyl disulfide regulates proliferation, apoptosis and aerobic glycolysis by down-regulating PKM2 in gastric cancer cells 二烯丙基二硫醚通过下调PKM2调控胃癌细胞增殖、凋亡和有氧糖酵解
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02634-8
Zhiyan Li, Baiwei Zhao, Deyao Zhang, J. Deng, Yongming Chen, Jian Zhou
{"title":"Diallyl disulfide regulates proliferation, apoptosis and aerobic glycolysis by down-regulating PKM2 in gastric cancer cells","authors":"Zhiyan Li, Baiwei Zhao, Deyao Zhang, J. Deng, Yongming Chen, Jian Zhou","doi":"10.23736/s2724-542x.20.02634-8","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02634-8","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"326 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75072071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple biomarker panel for the detection of circulating tumor cells in peripheral blood of breast cancer patients for early detection using the real-time reverse transcription-polymerase chain reaction 采用实时逆转录-聚合酶链式反应检测乳腺癌患者外周血循环肿瘤细胞的多种生物标志物面板，用于早期检测
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02645-2
Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar
{"title":"Multiple biomarker panel for the detection of circulating tumor cells in peripheral blood of breast cancer patients for early detection using the real-time reverse transcription-polymerase chain reaction","authors":"Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar","doi":"10.23736/s2724-542x.20.02645-2","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02645-2","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80002552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogel bead nanocomposite for the management of biomedical aqueous waste 水凝胶球纳米复合材料用于生物医学含水废物的处理
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.20.02643-9
Thiruvengadasamy R. Poorani, Sandhiyadevi Giri, Shazi Begum
{"title":"Hydrogel bead nanocomposite for the management of biomedical aqueous waste","authors":"Thiruvengadasamy R. Poorani, Sandhiyadevi Giri, Shazi Begum","doi":"10.23736/s2724-542x.20.02643-9","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02643-9","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"103 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88959097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiogenic potential of hypoxia preconditioned human adipose and umbilical cord-derived mesenchymal stem cells: a comparative study 缺氧预处理的人脂肪和脐带间充质干细胞的血管生成潜能:一项比较研究
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/s2724-542x.21.02749-x
V. Q. Pham, N. Tran, B. Vu, H. Le, N. Vu, P. Pham
{"title":"Angiogenic potential of hypoxia preconditioned human adipose and umbilical cord-derived mesenchymal stem cells: a comparative study","authors":"V. Q. Pham, N. Tran, B. Vu, H. Le, N. Vu, P. Pham","doi":"10.23736/s2724-542x.21.02749-x","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02749-x","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"27 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77560253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A contemporary insight into SARS-CoV-2 pathophysiology, retrieved threat of mutants and prospect of vaccine development SARS-CoV-2的病理生理、突变体的威胁和疫苗开发的前景
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-07-01 DOI: 10.23736/S2724-542X.21.02765-8
Rasmita Dash, S. Mohapatra
{"title":"A contemporary insight into SARS-CoV-2 pathophysiology, retrieved threat of mutants and prospect of vaccine development","authors":"Rasmita Dash, S. Mohapatra","doi":"10.23736/S2724-542X.21.02765-8","DOIUrl":"https://doi.org/10.23736/S2724-542X.21.02765-8","url":null,"abstract":"The COVID-19 pandemic has conceived a monstrous threat among the population. Here we portray some of the recent studies on COVID-19 which may supply bases for future research. This review brings a spotlight on the mode of transmission, pathophysiology, genetic structure, mutants of SARS-CoV-2, progress on the vaccination and some recent peculiar disguisable facts about the novel coronavirus 2019. Major scrutiny has been prepared on the new strains of SARS-CoV-2 and also a critical brief review on the ongoing vaccine research strategy and vaccine progress has been added further to that. Being in research this collection of data could have some advantageous response in the development of vaccines and understanding the actual behavior of SARS-CoV-2 in the research territory.","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"18 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90342223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperglycaemia-induced impaired neutrophil activity in the dynamic of burn wound healing in rats 高血糖诱导的中性粒细胞活性受损对大鼠烧伤创面愈合动态的影响
IF 1 4区 生物学
Minerva Biotechnology and Biomolecular Research Pub Date : 2021-04-01 DOI: 10.23736/s2724-542x.21.02793-0
L. Natrus, I. Ryzhko, O. Lisakovska
{"title":"Hyperglycaemia-induced impaired neutrophil activity in the dynamic of burn wound healing in rats","authors":"L. Natrus, I. Ryzhko, O. Lisakovska","doi":"10.23736/s2724-542x.21.02793-0","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02793-0","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":"24 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87776116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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