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International Journal of Pharmacognosy & Chinese Medicine最新文献

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Preliminary Phytochemical and Pharmacognostic Studies on a Well Known Medicinal Plant Trigonella foenum-graecum 著名药用植物葫芦巴的植物化学和生药学初步研究
International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000192
Vijay Danapur
{"title":"Preliminary Phytochemical and Pharmacognostic Studies on a Well Known Medicinal Plant Trigonella foenum-graecum","authors":"Vijay Danapur","doi":"10.23880/ipcm-16000192","DOIUrl":"https://doi.org/10.23880/ipcm-16000192","url":null,"abstract":"Fenugreek is commonly used as a spice in cooking and in small quantities is categorized as “Generally Recognized as Safe (GRAS)” by the U.S. Food and Drug Administration. Fenugreek is a member of the Leguminosae (Fabaceae) family and is commonly cultivated in India, Egypt, the Middle East and North Africa. The seeds of the plant have been used as a traditional remedy for numerous conditions including gastrointestinal disorders, gout, wound healing and inflammation, hyperlipidemia and diabetes. Bioactive compounds isolated from fenugreek seeds include saponins (ie: fenugreekine, diosgenin), alkaloids (i.e.,: trigonelline, gentianine, carpaine), amino acids, some of which act as insulin secretogogues (i.e.,: 4-hydroxyisoleucine, arginine), coumarins, mucilaginous fibers (galactomannan), nicotinic acid and other vitamins and minerals.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131659418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Phytochemical and Pharmacological Profile of Terminalia chebula chebula的植物化学和药理研究概况
International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000208
Maheep Kumar
{"title":"Phytochemical and Pharmacological Profile of Terminalia chebula","authors":"Maheep Kumar","doi":"10.23880/ipcm-16000208","DOIUrl":"https://doi.org/10.23880/ipcm-16000208","url":null,"abstract":"Plant secondary metabolites have been of interest to man for a long time due to their pharmacological relevance. In this search Terminalia chebula is widely used to enhance the natural resistance to various diseases. It is called the “king of medicines” and always listed first in the Ayurvedic meteria medica because of its extraordinary powers of healing. Traditionally it has been used as a popular folk medicine for homeostatic, antitussive, laxative, diuretic and cardio tonic treatments. Recent studies showed that it has also been used as antidiabetic, antiviral, cardioprotective, anticancer, antioxidant, free radical scavenging and hypolipidemic agent. The present review is an attempt to highlight the various ethnopharmacological and traditional uses as well as phytochemical and pharmacological aspect of Terminalia chebula.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126471279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pharmacognostic, Phytochemical and In Vivo Hepatoprotective Activity on Pongamia Pinnata Linn Bark 桄榔子皮的生药学、植物化学和体内保肝活性
International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000172
R. Devarakonda
{"title":"Pharmacognostic, Phytochemical and In Vivo Hepatoprotective Activity on Pongamia Pinnata Linn Bark","authors":"R. Devarakonda","doi":"10.23880/ipcm-16000172","DOIUrl":"https://doi.org/10.23880/ipcm-16000172","url":null,"abstract":"Pongamia pinnata Linnn (Fabaceae) is a tree/shrub with a broad distribution from India, south-eastern Asia, Indonesia and Australia. Different parts of the plant have been used in traditional medicine for bronchitis, whooping cough, rheumatic and diabetes. Transverse section and powder microscopy study of the bark showed phelloderms, cork cells, cortex cells, medullary rays, stone cells, calcium oxalate crystals and starch grains. The total ash 10.64% w/w. The acid insoluble ash 50.4% w/w, water soluble ash 49.1% w/w, The loss on dried 8% w/w, swelling index 5.4% w/w and foaming index was <100. The extractive values of bark powder of P. pinnata Linn was found to be more for ethanol solvent followed by distilled water, chloroform, ethyl acetate, petroleum ether. Preliminary phytochemical screening of hydro-alcoholic bark extract of P. pinnata Linn revealed the presence of flavonoids, phenolic compounds, tannins, alkaloids, carbohydrates, glycosides, and sterols gave positive reaction. The total phenolic, alkaloid and flavonoid contents of the hydro-alcoholic bark extract of P.pinnata Linn was found to be 68.96 ± 0.376 (mg GA/g). 52.06 ± 0.31 (mg AE/g) and 71.06 ± 0.11 (mg QE/g). From the column chromatography3-methoxy-(3´´,4´´-dihydro-3´´-hydroxy-4´´- acetoxy)-2´´,2´´-dimethylpyrano-(7,8:5´´,6´´)-flavone and Caryophyllene oxide compounds were isolated. The hydroalcoholic bark extract of P. pinnata Linn significantly decreases all the elevated levels of SGOT, SGPT, ALKP, TBL, CHL and increases TPTN and ALB levels at 400 and 800 mg/kg in rats when compared to standard drug silymarin.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131968791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of Murine Fertility by Kampo Formula Containing Astragalus Root Enhanced Endometrial Wnt/β-catenin Signaling Factors 黄芪汉布方增强子宫内膜Wnt/β-catenin信号因子对小鼠生育能力的影响
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000195
Kyoko Kobayashi
{"title":"Investigation of Murine Fertility by Kampo Formula Containing Astragalus Root Enhanced Endometrial Wnt/β-catenin Signaling Factors","authors":"Kyoko Kobayashi","doi":"10.23880/ipcm-16000195","DOIUrl":"https://doi.org/10.23880/ipcm-16000195","url":null,"abstract":"Astragalus root (Root of Astragalus membranaceaus (Fisch.) Bunge or Astragalus membranaceus var. mongholicus (Bunge) P.K.Hsiao) is a prescription drug constituting Kampo formulae with the aim of cardiotonic, hidroschesis, diuresis, and hypotensive effect in Japan. In this study, we report that hot water extract of Astragalus root (AsR) increased the number of neutrophils and the secretion of mucus from the endocervical gland in ovariectomized mice treated with estradiol. These secretions block bacterial access through the uterine cavity. Moreover, AsR and its main chemical component, AstragalosideⅣ, increased the levels of uterine Wnt4 and Wnt7a involved in endometrial proliferation and the maintenance of the stromasmooth muscle boundaries of the uterus, respectively. To explore the possibility of fertility improvement, we determine the litter size of maternal mice administrated with hot-water extract of Astragalus root or Kampo formula containing Astragalus root. AsR-treated maternal mice exhibited increased litter size by natural mating, whereas Keishikaogito which is a Kampo formula containing Astragalus root showed a trend towards decreased the litter size. These results suggest that Astragalus root mediates endometrial proliferation, leading to the improved fertility; a crude drug-component of Keishikaogito, except Astragalus root, might interfere with embryo implantation. The discovery of Kampo formulae showing increase of litter size is needed for treatment of fertility in medical care.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130221938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to Save Yourself from Corona Attack 如何从冠状病毒攻击中拯救自己
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000197
Dhananjay S Dongre
{"title":"How to Save Yourself from Corona Attack","authors":"Dhananjay S Dongre","doi":"10.23880/ipcm-16000197","DOIUrl":"https://doi.org/10.23880/ipcm-16000197","url":null,"abstract":"Here is a very simple way, using herbs, of how, you can kill the virus & dislocate the dead virus from the place where they have been able to place themselves, in the nose, throat, lungs Choose","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"3 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114093850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Anti Proliferative Activity of Thiosemicarbazone and 4-Thiazolidinones 硫代氨基脲酮和4-噻唑烷酮的合成及抗增殖活性研究
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000166
Monika Gupta
{"title":"Synthesis and Anti Proliferative Activity of Thiosemicarbazone and 4-Thiazolidinones","authors":"Monika Gupta","doi":"10.23880/ipcm-16000166","DOIUrl":"https://doi.org/10.23880/ipcm-16000166","url":null,"abstract":"Thiosemicarbazone and 4-Thiazolidinones are heterocyclic compounds with a broad spectrum of biological activities such as anti-inflammatory, anti-viral, anti-bacterial, anti-fungal and anticancer. A series of ten derivatives of thiosemicarbazone and 4-thiazolidinones derivatives was synthesised and evaluated for their antiproliferative activity against human breast cancer cells (MCF-7). The structure of compounds was established by IR and 1HNMR spectral studies. The synthesized compounds possessed good to moderate anticancer activity using Adriamycin as a standard. Out of ten synthesized compounds eight have GI50 value of <10 µg/ml demonstrating their potential activity. TGI for compound 6d was found to be comparable to Adriamycin (<10 µg/ml).","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124511865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evaluation of In-vitro Antibacterial and Anthelmintic Activities of Sauropus androgynus (Phyllanthaceae) Plant Extracts 雌雄同体龙柏(Phyllanthaceae)植物提取物体外抗菌和驱虫活性评价
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000160
Palaksha Mn
{"title":"Evaluation of In-vitro Antibacterial and Anthelmintic Activities of Sauropus androgynus (Phyllanthaceae) Plant Extracts","authors":"Palaksha Mn","doi":"10.23880/ipcm-16000160","DOIUrl":"https://doi.org/10.23880/ipcm-16000160","url":null,"abstract":"The present study was carried out to evaluate the qualitative analysis of various phytochemicals and in-vitro evaluation of antibacterial and anthelmintic activities of Ethanolic leaf extracts of Sauropus androgynus (Phyllanthaceae). The extracts were subjected to preliminary phytochemical screening for the identification of different phytoconstituents, the leaves indicated the presence of proteins, resins, steroids, tannins, glycosides, reducing sugar, carbohydrates, saponins, sterols, terpenoids, acidic compounds, cardiac glycosides, catechol, phenols, alkaloids, flavanoids. The different concentrations of Ethanolic extracts were subjected to antibacterial screening against various Gram positive and Gram negative bacteria and the results were compared with that of standard drug Gentamycin. Different concentrations of leaf extracts were tested to evaluate Anthelmintic activity using Sauropus androgynus (Indian earthworm). The extracts was found to possess vermifuge and vermicidal activity and the results were compared with standard drug Albendazole.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131806608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Review on Pharmacological Aspects of Arista 马兜铃的药理研究进展
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000167
Navjeet Singh
{"title":"A Review on Pharmacological Aspects of Arista","authors":"Navjeet Singh","doi":"10.23880/ipcm-16000167","DOIUrl":"https://doi.org/10.23880/ipcm-16000167","url":null,"abstract":"Arista (Azadirachta indica) is rapidly growing evergreen plant found commonly in India, Africa and America. Arista is the Sanskrit name of neem tree meaning “reliever of sickness’’ and hence is known as “sarbarogaribarini”. This contains many active chemicals viz., alkaloids, flavonoids, triterpenoids, phenolic compounds, carotenoids, steroids and ketones, biologically most active compound is azadirachtin. All parts of neem tree are commonly used in traditional Indian medicine for household remedy against various human diseases. This plant showed various medicinal activities such as antiallergic, antifungal, antibiotic, antidermatic, antibacterial, anti-inflammatory, insecticidal, larvicidal, antimalarial, and antiulcer. It also showed anti-cancerous and anti-HIV activity. Azadirachtin-A dose-dependently reduced hepatocellular necrosis in CCi4 imduced hepatotoxicity. The present paper enlightens the pharmacological profile of Arista vis-à-vis taxonomical status, chemical constituents and some major market formulations containing Arista as an important ingredient.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130520485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Carb Diet Outrank Low Fat Diet in Weight Loss 在减肥方面，低碳水化合物饮食比低脂肪饮食更重要
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000157
Shabnam Ansari
{"title":"Low Carb Diet Outrank Low Fat Diet in Weight Loss","authors":"Shabnam Ansari","doi":"10.23880/ipcm-16000157","DOIUrl":"https://doi.org/10.23880/ipcm-16000157","url":null,"abstract":"As per the study published in the Annals of Internal Medicine, a racially diverse group of 150 men and women were recruited to follow a specific diets for one year which particularly restricted them to eat wither carbohydrate or fat, but not overall calories.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132535264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethno-Eco-Chem-Medico and Tissue Culture Knowledge of the Asthma Climber-Antmool (Tylophora Indica) 哮喘攀缘蚁(Tylophora Indica)的民族-生态-化学-医学及组织培养知识
International Journal of Pharmacognosy &amp; Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000162
S. Khurana
{"title":"Ethno-Eco-Chem-Medico and Tissue Culture Knowledge of the Asthma Climber-Antmool (Tylophora Indica)","authors":"S. Khurana","doi":"10.23880/ipcm-16000162","DOIUrl":"https://doi.org/10.23880/ipcm-16000162","url":null,"abstract":"Antmool (Tylophora indica (Burm. F.) Merrill) is a highly potent medicinal plant for asthma from sub-Himalayan tract which extends from Uttar Pradesh to Meghalaya. This contains many active chemicals viz., tyloindicines, tylophorinine, isotylocrebrine, tylophorine etc. This covers information concerning its various medicinal values viz., anti-inflammatory, antitumor, antiallergic, antimicrobial, anti hyperglycaemic, anti hyperlipidemic, antioxidant, immunomodulatory, antistress activity, anti-plasmodium activity and free radical scavenging properties. The in vitro studies confirmed that this have broad-spectrum anti-microbial activity and also inhibitory effect on HIV. It is useful in Alcohol induced anxiety, myocardial damage. It is hepatoprotective and has diuretic activity. It can inhibit cellular immune responses. It is the famous remedy in Indian folk medicine since time immemorial for solving health issues viz., asthma, whooping cough, bronchitis, cold, cough, sore throat, snake bite, lucorrhoea and food poisoning. This has high medicinal recognition, so harvested on a large scale in an uncontrolled manner from its wild habitats.This review records various biotechnological approaches for large scale propagation of T. indica under in vitro conditions. This demonstrates the growth regulator synergy and even effect of explanting season. This also records results of culture studies and planting substrate used. The study carried out demonstrates that in vitro raised plant and callus produces better alkaloidal yields in comparison to the field plants. Novel antibacterial compounds can also be isolated from in vitro culture of explants. The review covers assessment of clonal fidelity, future of Ri T-DNA integrated rol Genes.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy &amp; Chinese Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125423266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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