Lancet Regional Health-Americas最新文献

{"title":"Epidemiology, incidence, and outcome of childhood cancers in the Afro-descendant population of the French West Indies and French Guiana: a population-based study","authors":"Claire Dichamp ,&nbsp;Brigitte Lacour ,&nbsp;Jacqueline Clavel ,&nbsp;Jean-Hugues Dalle ,&nbsp;Christelle Dufour ,&nbsp;Katell Michaux ,&nbsp;Stephanie Puget ,&nbsp;Benjamin Faivre ,&nbsp;Frederique Delion ,&nbsp;Nadjia Aigoun ,&nbsp;Yves Hatchuel ,&nbsp;Julie Mascle ,&nbsp;Hélène Denailly ,&nbsp;Arnaud Petit ,&nbsp;Guy Leverger ,&nbsp;Daniel Orbach ,&nbsp;Juliette Berry ,&nbsp;Nicolas Boissel ,&nbsp;Graziella Raimondo ,&nbsp;Sabine Sarnacki ,&nbsp;Arthur Felix","doi":"10.1016/j.lana.2025.101050","DOIUrl":"10.1016/j.lana.2025.101050","url":null,"abstract":"<div><h3>Background</h3><div>The epidemiology of childhood cancer in Afro-descendant (AD) populations is poorly described. We performed a descriptive study of the distribution, incidence, and survival of children with cancer in the French West Indies (FWI) and French Guiana (FG).</div></div><div><h3>Methods</h3><div>We included all patients aged 0–17 diagnosed with cancer or benign intracranial tumor between January 2011 and December 2021 and living in the FWI/FG area at time of diagnosis. The cases were identified from the French national registry of childhood cancer and cross-referenced with local sources. Incidence rates were calculated, and compared to that of mainland France by standardized incidence ratios (SIR). Vital status was completed up to the 31st of December 2023 (date of point). Relapses were identified and documented in pediatric reference centers in mainland France and local centers. The 5-year overall survival (5yOS) and event-free survival (5yEFS) were estimated using Kaplan–Meier method.</div></div><div><h3>Findings</h3><div>We identified 368 patients (26% leukemias, 21% central nervous system tumors, 12% lymphomas, and 41% others). The average age at diagnosis was 8.8 years (Range: 0.1–17.8), with 52% boys. The median follow-up was 4.4 years (Range: 0.1–12.3). The age standardized rates for all cancers was lower than in mainland France (124.9 vs 162.6 per million-year for children under 18 years old, SIR = 0.77 [95% CI: 0.69–0.85]). The 5yOS was 78.9% [95% CI: 73.9–83.0] and 5yEFS was 69.3% [95% CI: 63.9–74.0]. The 5yOS for the 0–14 age group was 81.2% [95% CI: 76.9–85.5].</div></div><div><h3>Interpretation</h3><div>This first registry-based study of childhood cancer in the FWI and FG shows that our patients with childhood cancer, treated in a country with a high standard of health care, has resulted in overall survival comparable to that of European and North American children.</div></div><div><h3>Funding</h3><div>The authors received no financial support.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101050"},"PeriodicalIF":7.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responding to medetomidine: clinical and public health needs","authors":"David T. Zhu ,&nbsp;Joseph J. Palamar","doi":"10.1016/j.lana.2025.101053","DOIUrl":"10.1016/j.lana.2025.101053","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101053"},"PeriodicalIF":7.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of COVID-19 vaccination with risks for post-infectious cardiovascular complications: an international cohort study in cancer patients with SARS-CoV-2 infection","authors":"Emily Pei-Ying Lin ,&nbsp;Chih-Yuan Hsu ,&nbsp;Sanjay Mishra ,&nbsp;Elizabeth A. Griffiths ,&nbsp;Brahm H. Segal ,&nbsp;Clara Hwang ,&nbsp;Sunny R.K. Singh ,&nbsp;Nino Balanchivadze ,&nbsp;Chinmay Jani ,&nbsp;Melissa G. Mariano ,&nbsp;Padmanabh S. Bhatt ,&nbsp;Kendra Vieira ,&nbsp;Peter Paul Yu ,&nbsp;Eric J. Oligino ,&nbsp;Trisha Wise-Draper ,&nbsp;Elizabeth K. Ferrara ,&nbsp;Rana R. McKay ,&nbsp;Taylor K. Nonato ,&nbsp;Chris Labaki ,&nbsp;Eddy Saad ,&nbsp;Yu Shyr","doi":"10.1016/j.lana.2025.101038","DOIUrl":"10.1016/j.lana.2025.101038","url":null,"abstract":"<div><h3>Background</h3><div>Whether COVID-19 vaccination is associated with risks for cardiovascular complications after SARS-CoV-2 infection in patients with cancer is unknown. The objective of this study was to investigate the associations between the two.</div></div><div><h3>Methods</h3><div>This registry (COVID-19 and Cancer Consortium)-based retrospective cohort study included patients with laboratory-confirmed SARS-CoV-2 infection from the United States, Canada, and Mexico between April 2021 and December 2022. Patients without COVID-19 vaccination were assigned to the unvaccinated group and patients with ≥2 doses of COVID-19 vaccination were assigned to the fully-vaccinated group. The primary outcome was a composite of post-infectious cardiac complications, including acute myocardial infarction, other ischemic heart disease, atrial fibrillation, ventricular fibrillation, other arrhythmias, cardiomyopathy, and congestive heart failure. The secondary outcome was a composite measure of post-infectious cardiovascular events, comprising of the cardiac complications along with pulmonary embolism, deep vein thrombosis, superficial vein thrombosis, other thrombosis, and cerebrovascular stroke. Multivariable logistic regression was used for data analysis.</div></div><div><h3>Findings</h3><div>A total of 2729 patients were included for analyses, with 1382 in the unvaccinated group and 1347 in the fully-vaccinated group. The median age of the study population was 65 (interquartile range (IQR), 55–74) years. Overall, 1534 (56.0%) were women; 1272 (47%) were never smokers; 1639 (60%) were not obese; 2043 (75%) had stable cancer, and 446 (16%) took anticoagulants at baseline. The primary and secondary analyses showed lower risks of cardiac complications and cardiovascular events in the fully-vaccinated group, with adjusted odds ratios (aOR) of 0.66 (95% confidence interval (CI), 0.48–0.89) and 0.76 (95% CI, 0.59–0.99), respectively. The protective trend with COVID-19 vaccination was observed across infections with different dominant SARS-CoV-2 strains and in patients with or without anticoagulant use.</div></div><div><h3>Interpretation</h3><div>COVID-19 vaccination was associated with a reduced risk of cardiac complications and cardiovascular events by 34% and 24%, respectively, after SARS-CoV-2 infection in patients with cancer.</div></div><div><h3>Funding</h3><div><span>National Institutes of Health USA</span>; <span>National Science and Technology Council of Taiwan</span>.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101038"},"PeriodicalIF":7.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“The end TB strategy” pathway in South America: out of track for 2025 milestones and 2035 eradication","authors":"Miguel Angel Garcia-Bereguiain ,&nbsp;Angel Sebastian Rodriguez-Pazmiño ,&nbsp;Greta Franco-Sotomayor ,&nbsp;Solon Alberto Orlando ,&nbsp;Manuel González ,&nbsp;Cesar Ugarte-Gil","doi":"10.1016/j.lana.2025.101045","DOIUrl":"10.1016/j.lana.2025.101045","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101045"},"PeriodicalIF":7.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing biobanking in Latin America: success stories and challenges ahead","authors":"Gustavo Sevlever ,&nbsp;Lucía Crivelli ,&nbsp;Claudia Kimie Suemoto ,&nbsp;Ezequiel Surace ,&nbsp;Analía Taratuto","doi":"10.1016/j.lana.2025.101047","DOIUrl":"10.1016/j.lana.2025.101047","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101047"},"PeriodicalIF":7.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stakeholder-driven multi-stage adaptive real-world theme-oriented (SMART) telehealth evaluation framework: a scoping review","authors":"Yunxi Zhang ,&nbsp;Yueh-Yun Lin ,&nbsp;Lincy S. Lal ,&nbsp;Jennifer C. Reneker ,&nbsp;Elizabeth G. Hinton ,&nbsp;Saurabh Chandra ,&nbsp;J. Michael Swint","doi":"10.1016/j.lana.2025.101041","DOIUrl":"10.1016/j.lana.2025.101041","url":null,"abstract":"<div><div>Telehealth has revolutionized healthcare delivery by integrating cutting-edge technologies, yet evaluations of its services and programs often lack comprehensive frameworks, resulting in unclear standards for quality assurance. To address this gap, we conducted a scoping review of telehealth evaluation frameworks applicable to the United States healthcare system, following the Joanna Briggs Institute methodology and a published protocol. Twelve telehealth evaluation frameworks published between 2019 and 2023 were identified, focusing on four key themes: program implementation, clinical impact, economic impact, and equity. Guided through two auxiliary frameworks, we further developed a stakeholder-driven multi-stage adaptive real-world theme-oriented (SMART) conceptual framework for telehealth evaluation. We illustrated this framework through a use case on a remote patient monitoring program. This comprehensive telehealth evaluation framework not only facilitates stakeholders in developing tailored evaluation plans but also contributes to the standardization and enhancement of telehealth services, ultimately improving health outcomes and promoting greater equity across society.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101041"},"PeriodicalIF":7.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific racism as a public health emergency of global concern","authors":"Francisco Jiménez-Trejo ,&nbsp;Katia L. Jiménez-García ,&nbsp;Telma Lisboa-Nascimento ,&nbsp;Santiago Rodríguez-Vega ,&nbsp;José L. Cervantes-Escárcega ,&nbsp;Gustavo Canul-Medina","doi":"10.1016/j.lana.2025.101049","DOIUrl":"10.1016/j.lana.2025.101049","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101049"},"PeriodicalIF":7.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The erosion of the US health-care workforce: silence is not an answer","authors":"The Lancet Regional Health – Americas","doi":"10.1016/j.lana.2025.101054","DOIUrl":"10.1016/j.lana.2025.101054","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"43 ","pages":"Article 101054"},"PeriodicalIF":7.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The silent trauma: U.S. immigration policies and mental health","authors":"Omid Dadras ,&nbsp;Mohammad Sediq Hazratzai","doi":"10.1016/j.lana.2025.101048","DOIUrl":"10.1016/j.lana.2025.101048","url":null,"abstract":"","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"44 ","pages":"Article 101048"},"PeriodicalIF":7.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approaching pediatric mental health screening and care in immigration detention","authors":"Shela Sridhar ,&nbsp;Leah Ratner ,&nbsp;Matthew G. Gartland ,&nbsp;Dennis Kunichoff ,&nbsp;Margaret M. Sullivan ,&nbsp;Vasileia Digidiki","doi":"10.1016/j.lana.2025.100999","DOIUrl":"10.1016/j.lana.2025.100999","url":null,"abstract":"<div><div>Children held in US immigration detention facilities often arrive with significant mental health conditions requiring prompt attention. Despite the abundance of literature highlighting the need for adequate mental health care in migrant children, there is a chasm between the care offered to detained migrant children in the US and the minimum standards of healthcare in the US. This discrepancy is fueled by the mandate of Immigration and Customs Enforcement (ICE), which prioritizes immigration enforcement rather than the health and well-being of detained children. The tension between the existing ICE's enforcement mandate and the internationally recognized right to health care for children results in inadequate mental health care, causing long-term harm. We highlight current pediatric mental health screening and treatment practices in immigration detention facilities, exploring the role of ICE and child protection frameworks. We conclude by providing policy recommendations to improve mental health care in US-based detention facilities.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"43 ","pages":"Article 100999"},"PeriodicalIF":7.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}