Lancet Regional Health-Americas最新文献_第10页

Children are family members too: can we continue to keep the door closed for them? 孩子也是家庭成员：我们能继续为他们关上大门吗？

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2024.100970

Bruna Brandao Barreto , Mariana Luz , Dimitri Gusmao-Flores

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Decarceration and COVID-19 infections in U.S. Immigration and Customs Enforcement detention facilities: a simulation modeling study 美国移民和海关执法局拘留设施的隔离和COVID-19感染：一项模拟建模研究

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2024.100971

Christopher Weyant , Jaimie P. Meyer , Daniel Bromberg , Chris Beyrer , Frederick L. Altice , Jeremy D. Goldhaber-Fiebert

{"title":"Decarceration and COVID-19 infections in U.S. Immigration and Customs Enforcement detention facilities: a simulation modeling study","authors":"Christopher Weyant , Jaimie P. Meyer , Daniel Bromberg , Chris Beyrer , Frederick L. Altice , Jeremy D. Goldhaber-Fiebert","doi":"10.1016/j.lana.2024.100971","DOIUrl":"10.1016/j.lana.2024.100971","url":null,"abstract":"<div><h3>Background</h3><div>U.S. Immigration and Customs Enforcement (ICE) facilities had high rates of COVID-19 infections and mortality during the global pandemic. We sought to quantify how many COVID-19 infections could have been averted through different decarceration strategies.</div></div><div><h3>Methods</h3><div>We developed a set of stochastic simulation models of SARS-CoV-2 transmission in ICE facilities. Employing incremental mixture importance sampling (IMIS), we calibrated them to empirical targets derived from publicly available case time series for ICE facilities, and publicly available facility population censuses prior to vaccine availability (May 6, 2020 to December 31, 2020). The models included infection importation from extra-facility sources. We evaluated reduction of the incarcerated population by 10–90%. People who were decarcerated faced background cumulative risks of infection and detection based on a weighted average of county-level estimates from the covidestim model, which is a Bayesian evidence synthesis model.</div></div><div><h3>Findings</h3><div>Without decarceration, the infection rate was 5.05 per 1000 person-days (95% CrI 3.40–6.81) and case rate was 1.53 per 1000 person-days (95% CrI 1.04–2.02). Rates declined linearly when decarceration did not reduce contacts of people remaining in facilities and faster than linearly when it did reduce contacts. At all decarceration levels, rates were substantially higher when contacts were not reduced. Even with 90% decarceration, infection rates for people remaining in facilities were higher than or comparable to otherwise similar free-living people.</div></div><div><h3>Interpretation</h3><div>The decline in COVID-19 infection rates with decarceration was linear or faster than linear depending on how decarceration was implemented. Our findings highlight infection risks associated with incarceration, which compound other health harms of incarceration.</div></div><div><h3>Funding</h3><div><span>Stanford’s COVID-19 Emergency Response Fund</span>; the <span>National Institute on Drug Abuse</span>; and the <span>National Institute of Mental Health</span>.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"42 ","pages":"Article 100971"},"PeriodicalIF":7.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Bridging the gap of cardiovascular disease burden in the Americas: a call for action

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2025.101023

Daniel Diaz , Diana Z. Velazquez-Valdez , Pavel E. Hernandez-Carreño , Saul A. Beltran-Ontiveros , Edgar L. Gonzalez-Gonzalez , Lina S. Palacio-Mejia

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Venous thromboembolism (VTE) prevention program implementation in a community oncology practice: author response to Yang et al

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2024.100980

Steven Ades, Chris Holmes

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Los Angeles County in flames: responsibilities on fire

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2025.101005

Orison O. Woolcott

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The complex landscape of abortion law and public health in Brazil

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2024.100987

Felipe Ornell , Anne Orgler Sordi , Bárbara Sordi Stock , Juliana Nichterwitz Scherer , Joana Corrêa de Magalhães Narvaez

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“Sleepy Joe”, “el loco”, and evolving debates about mental health and democratic leadership in the Americas

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2025.100992

Alexander J. Smith , Agustín Artese , Maria A. Oquendo , Dinesh Bhugra , Helena Ferreira Moura , Michael Liebrenz

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Mental health disparities among maternal populations following heatwave exposure in North Carolina (2011–2019): a matched analysis

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2025.100998

Sarah E. Ulrich , Margaret M. Sugg , Dennis Guignet , Jennifer D. Runkle

{"title":"Mental health disparities among maternal populations following heatwave exposure in North Carolina (2011–2019): a matched analysis","authors":"Sarah E. Ulrich , Margaret M. Sugg , Dennis Guignet , Jennifer D. Runkle","doi":"10.1016/j.lana.2025.100998","DOIUrl":"10.1016/j.lana.2025.100998","url":null,"abstract":"<div><h3>Background</h3><div>The increasing incidence of extreme heat due to climate change poses a significant threat to maternal mental health in the U.S. We examine the association of acute exposure to heatwaves with maternal mental health conditions in North Carolina from 2011 to 2019.</div></div><div><h3>Methods</h3><div>We incorporate a matched analysis design using NC Hospital Discharge Data to examine emergency department admissions for psychiatric conditions during the warm season (May to September), matching heatwave periods with non-heatwave unexposed periods at the zip code tabulation area (ZCTA) level. We stratify the sample to examine effect modification across the rural-urban continuum, physiographic regions, measurements of neighborhood racial and economic inequality, and individual-level sociodemographic factors (e.g., age, race/ethnicity, and insurance type).</div></div><div><h3>Findings</h3><div>Our sample of 324,928 emergency department visits by pregnant individuals has a mean age of 25.8 years (SD: 5.84), with 9.3% (n = 30,205) identifying as Hispanic. Relative risk (RR) estimates and 95% confidence intervals (CI) indicate significant increases in maternal mental health burdens following heatwave exposure. Acute heatwave periods were associated with a 13% higher risk of severe mental illness (RR<sub>SMI</sub>: 1.13, CI: 1.08–1.19, <em>p</em>: <0.0001), while prolonged exposure to moderate-intensity heatwaves was associated with 37% higher risk (RR<sub>SMI</sub>: 1.37, CI: 1.19–1.58, <em>p</em>: <0.001). Individual factors (e.g., advanced maternal age and insurance providers) and neighborhood-level characteristics, like low socioeconomic status, racialized and economic segregation, rurality, and physiographic region, further modified the risk of adverse maternal mental health outcomes.</div></div><div><h3>Interpretation</h3><div>Our results add to the growing evidence of the impact of extreme heat on maternal mental health, particularly among vulnerable subpopulations. Additionally, findings emphasize the influence of socioeconomic and environmental contexts on mental health responses to heatwave exposure.</div></div><div><h3>Funding</h3><div>This work was supported by the <span>Faculty Early Career Development Program</span> (CAREER) award (grant <span><span>#2044839</span></span>) from the <span>National Science Foundation</span> and the <span>National Institute of Environmental Health Sciences</span> (NIEHS) award (grant <span><span>#5R03ES035170-02</span></span>).</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"42 ","pages":"Article 100998"},"PeriodicalIF":7.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastrointestinal cancers among Asian American and Pacific Islander populations

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2024.100989

Erin Jay G. Feliciano , Edward Christopher Dee

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Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study

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Lancet Regional Health-Americas Pub Date : 2025-02-01 DOI: 10.1016/j.lana.2025.100994

Jean Marc Pujo , Stephanie Houcke , Guy Roger Lontsi Ngoulla , Vivian Laurent , Boubacar Signaté , Rémi Mutricy , Alexis Frémery , Flaubert Nkontcho , Ibtissem Ben Amara , José María Gutiérrez , Dabor Resiere , Hatem Kallel

{"title":"Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study","authors":"Jean Marc Pujo , Stephanie Houcke , Guy Roger Lontsi Ngoulla , Vivian Laurent , Boubacar Signaté , Rémi Mutricy , Alexis Frémery , Flaubert Nkontcho , Ibtissem Ben Amara , José María Gutiérrez , Dabor Resiere , Hatem Kallel","doi":"10.1016/j.lana.2025.100994","DOIUrl":"10.1016/j.lana.2025.100994","url":null,"abstract":"<div><h3>Background</h3><div>Snakebite (SB) envenoming is an acute emergency requiring early care delivery. However, sometimes, patients can take several hours before receiving antivenom (AV). We conducted this study to assess the effectiveness of antivenom in the recovery of clotting parameters in patients consulting tardily after SB envenoming in French Guiana. The primary endpoint of our study was to investigate the time needed from SB to recovery from SB-induced coagulopathy. The secondary endpoint was to investigate the time needed from AV administration to recovery from SB-induced coagulopathy in patients receiving AV (late or very late administration).</div></div><div><h3>Methods</h3><div>This prospective observational study was conducted in the Intensive Care Unit (ICU) of Cayenne General Hospital between January 2016 and September 2023. We included all patients hospitalized for SB envenoming who either did not receive AV or received it more than 6 h after SB. We excluded patients who received antivenom in less than 6 h from the SB and those who received incomplete AV doses.</div></div><div><h3>Findings</h3><div>We included 58 patients in the No AV group, 51 in the late AV group (6 h ≤ AV < 12 h), and 50 in the very late AV group (AV≥12 h). The median age of patients was 42 years (IQR: 29–53), 65.4% were male and 34.6% were female (104 and 55 out of 159 patients) without difference regarding the demographic parameters between groups. Data regarding ethnicity was not available. The median time from SB to AV was 8.5 h (IQR: 6.9–10) in the late AV group and 21.1 h (IQR: 16.7–27.4) in the very late AV group (p < 0.001). The time from SB to normal clotting parameters was shorter in patients receiving late AV than in those receiving very late AV and those not receiving AV. No differences were observed in the time from SB and recovery of fibrinogen and activated partial thromboplastin time (aPTT) between very late AV and no AV. However, the International Normalized Ratio (INR) recovery was shorter in the very late AV group than in the no AV group. On the other hand, the time from AV to normal fibrinogen was shorter in patients receiving very late AV than in patients receiving late AV (Log-Rank = 0.020). Meanwhile, the time from AV to normal INR or normal aPTT was similar in patients receiving very late AV compared to patients receiving late AV (Log-Rank = 0.722 and 0.740, respectively).</div></div><div><h3>Interpretation</h3><div>Late AV administration effectively reverses coagulopathic manifestations after SB envenoming. However, very late AV administration did not improve the correction of some clotting parameters when compared to patients not receiving AV. Our findings could be explained by the combination of venom toxicokinetics and the kinetics of the synthesis of clotting factors.</div></div><div><h3>Funding</h3><div>No funding.</div></div>","PeriodicalId":29783,"journal":{"name":"Lancet Regional Health-Americas","volume":"42 ","pages":"Article 100994"},"PeriodicalIF":7.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0