Journal of Integrative and Complementary Medicine最新文献

{"title":"Integrating Chiropractic Care and Tai Chi Training for the Treatment of Chronic Nonspecific Neck Pain in Nurses: A Single-Arm Mixed-Methods Pilot Trial.","authors":"Wren Burton, Peter M Wayne, Dan Litrownik, Cynthia R Long, Robert Vining, Pamela Rist, Karen Kilgore, Anthony Lisi, Matthew H Kowalski","doi":"10.1089/jicm.2024.0043","DOIUrl":"10.1089/jicm.2024.0043","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Chronic nonspecific neck pain (CNNP) is prevalent among health care workers, with particularly high rates among nurses. Nurses experiencing CNNP often report decreased job satisfaction, increased absenteeism, and reduced productivity. In recent years, nonpharmacologic approaches have gained attention as effective treatments for the management of CNNP, with exercise and manual therapies representing two of the most common. Early evidence shows that multimodal treatments may be more effective than unimodal strategies. The purpose of this current study was to assess the feasibility and observe the clinical outcomes of combined multimodal chiropractic care (MCC) and Tai Chi (TC) for CNNP in nurses. <b><i>Methods:</i></b> A single-arm mixed-methods pilot trial was conducted including 16 weeks of MCC and TC in nurses with self-reported CNNP. Feasibility outcomes were recruitment, retention, and adherence to the interventions. Clinical outcomes of interest included neck pain and related disabilities. Secondary outcomes of interest were functional, affective, and work-related performance. Qualitative interviews were also conducted. <b><i>Results:</i></b> Of the 59 screened, 36 met the eligibility criteria, and 21 were enrolled. The retention rate was 71.4%, and adherence rates were 85.3% for MCC and 62.5% for TC classes. Multiple pain and disability-related outcomes exhibited modest improvement from baseline to 16-week follow-up. Qualitative analysis identified six emergent themes: (1) neck pain being an inherent part of nursing, (2) nurses push through their pain, (3) MCC relieves pain and is instructive for preventing pain, (4) TC provides overall relaxation, (5) both interventions increased body awareness and improved posture, and (6) scheduling difficulties were a key obstacle for participating. <b><i>Conclusions:</i></b> Observed reductions in neck pain and disability suggest the potential utility of combined MCC and TC interventions for managing CNNP. Along with qualitative feedback regarding facilitators and barriers to participation, the findings support and inform a future randomized trial evaluating the combined benefits of MCC and TC for CNNP in nurses. Clinical Trial Registration #NCT06523036.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1189-1199"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole Health Research Thought Further: How Can We Stay Whole in a Reductionist Paradigm?","authors":"Holger Cramer","doi":"10.1089/jicm.2024.0929","DOIUrl":"10.1089/jicm.2024.0929","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1123-1124"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Binaural Beats on Anxiety and Tolerance in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation: A Randomized Controlled Trial.","authors":"Selim Demirci, Semih Sezer","doi":"10.1089/jicm.2023.0804","DOIUrl":"10.1089/jicm.2023.0804","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Binaural beats, or the perceptual auditory illusions created when simultaneously presenting two similar frequencies to each ear separately, have been used to reduce anxiety in various procedures. Unfortunately, no prior study involved preprocedure binaural music exposure among patients undergoing upper gastrointestinal endoscopy, and this study sought to investigate its effect on anxiety and tolerance among participants undergoing sedation-free upper gastrointestinal endoscopy. <b><i>Methods:</i></b> The prospective, controlled, randomized trial included the participation of 96 Turkish patients aged between 18 and 70 years who were scheduled for an upper gastrointestinal endoscopy, regardless of sex or illness, and were divided randomly into two different groups to undergo endoscopy, namely, the binaural beats group (<i>n</i> = 48) and a control group (<i>n</i> = 48). Patients in the binaural beat music group wore headphones, and music was given 15 mins before endoscopy; however, no particular treatment was given for either group. Anxiety levels were assessed by using the State Trait Anxiety Inventory questionnaire, in addition to changes before and after endoscopy to measure patient satisfaction based on the physician's recorded numbers of retches noted by doctors as tolerance was documented and compared among both groups. <b><i>Results:</i></b> The results showed that following this procedure, in the music group, state scores remained significantly lower than before them (<i>p</i> = 0.016), compared with the control group (<i>p</i> > 0.05). There was no significant difference regarding changes in diastolic or systolic heart rate or blood pressure (<i>p</i> > 0.05). However, the procedure tolerance and satisfaction scores were significantly higher in the music group than those without music (<i>p</i> < 0.05). <b><i>Conclusion:</i></b> For patients undergoing upper gastrointestinal endoscopy, music with binaural beats was found to significantly reduce anxiety levels and increase patient tolerance, providing an alternative option to sedative medications as a potential sedative treatment option.Clinical trials registration number: NCT06114524.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1209-1216"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring In-Session Engagement in Equine-Assisted Services for Children and Youth Experiencing Disability: A Scoping Review.","authors":"Lena M Aewerdieck, Rachelle A Martin, Fiona P Graham, Jean Hay-Smith","doi":"10.1089/jicm.2024.0151","DOIUrl":"10.1089/jicm.2024.0151","url":null,"abstract":"<p><p><b><i>Aims:</i></b> The purpose of this review was to identify and describe the evidence about children and youth engagement during equine-assisted services (EAS). <b><i>Methods:</i></b> Five databases (Scopus, Web of Science, PsycINFO, CINAHL, and MEDLINE) were systematically searched. Included studies reported research about EAS conducted in children and youth and presented findings about in-session engagement or associated concepts such as motivation, involvement, and participation. Extracted data (study type, equine intervention, population, and the studies' key focus) were summarized descriptively, followed by inductive content analysis of the main mechanisms proposed to influence engagement. <b><i>Results:</i></b> In total, 30 studies were identified; however, only three centered on rider engagement as the primary focus of research. Other publications addressed in-session engagement within service descriptions or results and discussion sections. Three mechanisms that influence engagement within EAS were derived: (1) the unique EAS landscape, (2) the horse-child relationship and (3) the provider-child relationship. The literature primarily referred to horses as the most important factor influencing child and youth engagement in EAS sessions. Little attention was given to the influence of service providers', parents', or child preferences on engagement. <b><i>Conclusions:</i></b> The child/youth-parent-provider relational triad and specific strategies to improve rider engagement within EAS sessions warrants further investigation.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1147-1161"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141559947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative Health and Wellness Coaching: A Call to Action to Address a Research Gap for Individuals with Intellectual and Developmental Disabilities.","authors":"Alyssa Morgan Smith, Shelley R Adler, Patricia Prelock, Jeremy Sibold, Karen Westervelt, Ruth Q Wolever","doi":"10.1089/jicm.2024.0859","DOIUrl":"10.1089/jicm.2024.0859","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1130-1133"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Mindfulness Training and Interoceptive Awareness in Pregnant People at Risk for Hypertensive Disorders.","authors":"Meghan Sharp, L G Ward, Madison Pomerantz, Ghada Bourjeily, Kate M Guthrie, Elena Salmoirago-Blotcher, Amanda Desmarattes, Margaret H Bublitz","doi":"10.1089/jicm.2024.0121","DOIUrl":"10.1089/jicm.2024.0121","url":null,"abstract":"<p><p><b><i>Aim:</i></b> In this secondary analysis of a pilot randomized controlled trial (RCT), we sought to examine whether mindfulness training (MT) is associated with change in interoceptive awareness in pregnant people at risk for hypertension using quantitative and qualitative methods. Interoceptive awareness is the perception, regulation, and integration of bodily sensations. Interoceptive awareness increases following MT and has been proposed as a psychosomatic process underlying hypertension outside of pregnancy. <b><i>Methods:</i></b> Twenty-nine participants (mean age 32 ± 4 years; 67% White) with a history of hypertensive disorders of pregnancy (HDP) were enrolled at 16 weeks' gestation (SD = 3) for a RCT assessing the feasibility and acceptability of an 8-week phone-delivered MT intervention. Fifteen participants were randomized to MT, whereas 14 were randomized to usual prenatal care. Before and after the intervention, all participants completed the Multidimensional Assessment of Interoceptive Awareness (MAIA) measure and participated an individual interview, which queried for mind-body changes noticed across the study period. <b><i>Results:</i></b> Adjusting for baseline interoceptive awareness and gestational age, participants randomized to MT reported less worry about physical sensations on the MAIA after the intervention compared to those randomized to usual care. Qualitative data corroborated these results; MT participants described improved awareness of body and breath sensations, ability to notice blood pressure changes, non-judgmental observation of thoughts, and improved responses to interpersonal challenges. <b><i>Conclusions:</i></b> MT may improve the ability to notice body sensations that arise in pregnancy in a way that promotes healthy responding rather than worry. Results provide support for interoceptive awareness as a potential mechanism through which mindfulness may modulate blood pressure and potentially reduce the prevalence of HDP. C<b><i>linical Trial Registration:</i></b> ClinicalTrials.gov (NCT03679117).</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1200-1208"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141559950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the Two Worlds: Worldwide Reflections on the 2024 Hong Kong SAR/PolyU Conference.","authors":"Jerry Wing-Fai Yeung, Afua Bromley, Younbyoung Chae, Denise Shuk Ting Cheung, Lisa Conboy, Sandro Graca, Kate Levett, Kathleen Lumiere, Rosa Schnyer, Kristen Sparrow, Liming Tseng, John Yoo, Yu-Qing Zhang, Claudia Citkovitz","doi":"10.1089/jicm.2024.0819","DOIUrl":"10.1089/jicm.2024.0819","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1125-1129"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative Statistical Model Uncover Effective Herbal Medicines Among Personalized Treatment Plans in Persian Medicine: A Small-Scale Study in Type 2 Diabetes.","authors":"Samaneh Eftekhari Mahabadi, Reza Khalifeh, Roshanak Ghods, L Susan Wieland, Ricardo Ghelman, Asie Shojaii, Armin Zareian, Nafiseh Hosseini Yekta","doi":"10.1089/jicm.2024.0180","DOIUrl":"10.1089/jicm.2024.0180","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> In holistic medicine, developing personalized treatment plans is challenging due to the multitude of possible therapy combinations. This study introduces the use of a statistical approach to identify the most effective herbal medicines prescribed in Persian medicine (PM) in a small-scale sample of patients with type 2 diabetes mellitus (T2DM). <b><i>Methods:</i></b> This prospective observational cohort study was conducted with 47 patients with T2DM referred to Behesht Clinic in Tehran, Iran. A physician prescribed individualized PM treatment for T2DM and related systemic issues. The fasting blood sugar (FBS) level of each patient was recorded at initial and two follow-up visits, with visit intervals and treatment modifications determined by patient health status. Patients who completed two follow-up visits were included in the final analysis (<i>n</i> = 27). Data were analyzed using R software. A general linear model was assumed for the mean response, along with an exponential covariance pattern model, to manage irregularly timed measurements. <b><i>Results:</i></b> Two fitted models showed that, after adjusting for confounders, the use of the \"Diabetes Capsule\" significantly reduced the average FBS by 17.14 mmol/L (<i>p</i> = 0.046). For each unit increase in the consumption of \"Diabetes Capsule\" or \"Hab-e-Amber Momiai,\" the average FBS decreased by 15.22 mmol/L (<i>p</i> = 0.015) and 14.14 mmol/L (<i>p</i> = 0.047), respectively. <b><i>Conclusion:</i></b> It is possible to observe which medications are most effective, even when treatments are applied in a holistic and personalized fashion. Preliminary studies such as these may identify promising products for testing in clinical trials conducted under standardized conditions, to inform initial choices for future personalized treatments.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1217-1230"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and Facilitators to Integrating Acupuncture into the U.S. Health Care System: A Scoping Review.","authors":"Hongjin Li, Juanita E Darby, Ivy Akpotu, Judith M Schlaeger, Crystal L Patil, Oana Danciu, Andrew D Boyd, Larisa Burke, Miriam O Ezenwa, Mitchell R Knisely, Ta-Ya Lee, Molly W Mandernach, Victoria A de Martelly, Robert E Molokie, Nirmish Shah, Diana J Wilkie, Ardith Z Doorenbos","doi":"10.1089/jicm.2023.0603","DOIUrl":"10.1089/jicm.2023.0603","url":null,"abstract":"<p><p><b><i>Background:</i></b> Acupuncture is a widely practiced complementary and integrative health modality that has multiple clinical applications. The use of acupuncture in the United States is rapidly increasing. Although studies have shown the efficacy and effectiveness of acupuncture for various ailments, the integration of acupuncture into the U.S. health care system remains a challenge. Little is known about the factors affecting this integration. <b><i>Objective:</i></b> To provide a systematic review of the barriers and facilitators affecting the integration of acupuncture into the U.S. health care system. <b><i>Methods:</i></b> Four electronic databases were searched. Three independent reviewers were involved in the screening and data charting processes. Findings were synthesized and categorized into four levels based on the Social Ecological Model. <b><i>Results:</i></b> A total of 22 studies were included in the final review. The barriers and facilitators affecting the integration of acupuncture were mapped into four levels (individual, interpersonal, organizational, and policy). The most frequently reported barriers and facilitators were mapped into the Social Ecological Model constructs within the \"Individual\" level (i.e., beliefs and attitudes of acupuncture, and practical issues) and the \"Organizational\" level (i.e., credentialing, space and facility, referral system). <b><i>Conclusion:</i></b> This review has identified and synthesized the breadth of evidence on the barriers and facilitators to the integration of acupuncture into the U.S. health care system. Results of this review will guide future implementation studies to develop and test implementation strategies to integrate acupuncture into the U.S. health care system.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1134-1146"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Menstrual Irregularities with Individualized Homeopathic Medicinal Products in Early Reproductive Females: A Double-Blind, Randomized, Placebo-Controlled Trial.","authors":"Usashi Nag, Rajat Kumar Pal, Subhranil Saha, Sk Monsur Alam, Tahira Parvin, Raghubir Gole, Pintu Debnath, Sumana Sengupta, Mousumi Koley, Urmi Roy, Junayed Akram, Abdur Rahaman Shaikh, Munmun Koley, Shyamal Kumar Mukherjee","doi":"10.1089/jicm.2024.0050","DOIUrl":"10.1089/jicm.2024.0050","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Prevalence of irregular menstrual cycle ranges from 81.7% to 96.3%. Recent research suggested that homeopathy is one of the most popular choices for women with various gynecological disorders. This trial was aimed at differentiating individualized homeopathic medicinal products (IHMPs) from identical-looking placebos in the treatment of menstrual irregularities in early reproductive women. <b><i>Design:</i></b> Double-blind, randomized (1:1), two parallel arms, placebo-controlled trial. <b><i>Setting:</i></b> D. N. De Homoeopathic Medical College & Hospital, Kolkata, West Bengal, India. <b><i>Subjects:</i></b> Ninety-two females with menstrual irregularities. <b><i>Interventions:</i></b> Group verum (<i>n</i> = 46; IHMPs plus concomitant care) versus group control (<i>n</i> = 46; placebos plus concomitant care). <b><i>Outcome Measures:</i></b> Primary-The proportion of early reproductive females in whom menstrual irregularities can be corrected for consecutive three cycles; Secondary-Menstrual Distress Questionnaire (MDQ) total score; all of them were measured at baseline and every month, up to 4 months. <b><i>Results:</i></b> Intention-to-treat sample (<i>n</i> = 92) was analyzed. Group differences were examined by chi-squared tests with categorical outcomes, two-way repeated measure analysis of variance accounting for the time-effect interactions, and unpaired <i>t</i>-tests comparing the mean estimates obtained individually every month. The level of significance was set at <i>p</i> < 0.05 two-tailed. After 4 months of intervention, the group difference in the primary outcome was nonsignificant statistically-IHMPs: 22/46 v/s placebo: 24/46, chi-square (Yates corrected) = 0.043, <i>p</i> = 0.835. The improvement observed in the MDQ total score (<i>F</i>₁,₉₀ = 0.054, <i>p</i> = 0.816) and subscales scores were higher in the IHMPs group than in placebos, however statistically nonsignificant in most of the occasions, except for the behavioral change subscale (<i>F</i>₁,₉₀ = 0.029, <i>p</i> < 0.001). <i>Pulsatilla nigricans</i> was the most frequently prescribed medicine. Kent's Repertory and Zandvoort's Complete Repertory were the most frequently used repertories. No harm or serious adverse events were reported from either group. <b><i>Conclusions:</i></b> The analysis failed to demonstrate clearly that IHMPs were effective beyond placebos in all but one of the outcomes. More appropriate outcome measures may be sought for future trials. <b><i>Clinical Trial Registration Number:</i></b> CTRI/2022/04/041659.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1231-1242"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}