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D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES最新文献

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Targeting the HO-1/CO Pathway with Sanguinate: Toward Development of a Novel Anti-inflammatory Therapy for Cystic Fibrosis (CF) Lung Disease 用血酸盐靶向HO-1/CO通路:囊性纤维化(CF)肺部疾病的新型抗炎疗法的发展
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6187
C. Pietro, H. Oz, V. Martis, Ping-xia Zhang, R. Jubin, A. Abuchowski, D. Krause, M. Egan, T. Murray, E. Bruscia
{"title":"Targeting the HO-1/CO Pathway with Sanguinate: Toward Development of a Novel Anti-inflammatory Therapy for Cystic Fibrosis (CF) Lung Disease","authors":"C. Pietro, H. Oz, V. Martis, Ping-xia Zhang, R. Jubin, A. Abuchowski, D. Krause, M. Egan, T. Murray, E. Bruscia","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6187","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6187","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"264 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121407570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic Reprogramming of the Cystic Fibrosis Neutrophil Drives Interleukin-1β via the NLRP3 Inflammasome 囊性纤维化中性粒细胞代谢重编程通过NLRP3炎性体驱动白细胞介素-1β
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6188
O. McElvaney, Z. Zaslona, E. Pålsson-McDermott, C. Gunaratnam, L. O’Neill, E. Reeves, N. McElvaney
{"title":"Metabolic Reprogramming of the Cystic Fibrosis Neutrophil Drives Interleukin-1β via the NLRP3 Inflammasome","authors":"O. McElvaney, Z. Zaslona, E. Pålsson-McDermott, C. Gunaratnam, L. O’Neill, E. Reeves, N. McElvaney","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6188","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6188","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"42 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133499306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Macrophages in Chronic CF Lung Inflammation, Resolution and Remodeling 巨噬细胞在慢性CF肺炎症、消退和重塑中的作用
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6186
H. H. Oz, C. Pietro, E. Cheng, Ping-xia Zhang, R. Nguyen, C. Barone, D. Krause, M. Egan, E. Bruscia
{"title":"Macrophages in Chronic CF Lung Inflammation, Resolution and Remodeling","authors":"H. H. Oz, C. Pietro, E. Cheng, Ping-xia Zhang, R. Nguyen, C. Barone, D. Krause, M. Egan, E. Bruscia","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6186","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6186","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129310008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of BAL Fluid Gliotoxin on Mesenchymal Stromal-Based Cell Therapies BAL液体胶质毒素对间充质基质细胞治疗的影响
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6195
S. R. Enes, S. Abreu, T. Hampton, Robert A Cramer, B. Stanton, M. Wargo, D.J. Weiss
{"title":"The Impact of BAL Fluid Gliotoxin on Mesenchymal Stromal-Based Cell Therapies","authors":"S. R. Enes, S. Abreu, T. Hampton, Robert A Cramer, B. Stanton, M. Wargo, D.J. Weiss","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6195","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6195","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125653444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electric Cell- Substrate Impedance Sensing Reveals Defective Permeability in Cystic Fibrosis Bronchial Epithelial Cells 细胞-基质阻抗传感揭示囊性纤维化支气管上皮细胞通透性缺陷
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6192
C. Sendon, C. Dipietro, H. Oez, C. Barone, R. Pierce, M. Egan, E. Bruscia
{"title":"Electric Cell- Substrate Impedance Sensing Reveals Defective Permeability in Cystic Fibrosis Bronchial Epithelial Cells","authors":"C. Sendon, C. Dipietro, H. Oez, C. Barone, R. Pierce, M. Egan, E. Bruscia","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6192","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6192","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132319932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
iPSC-Derived Bronchospheres as a Novel Platform for Cystic Fibrosis Drug Development ipsc衍生支气管球作为囊性纤维化药物开发的新平台
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6197
A. Berical, M. Beermann, Dylan C. Thomas, N. Ranallo, P. McNally, K. Hurley, S. Randell, D. Kotton, F. Hawkins
{"title":"iPSC-Derived Bronchospheres as a Novel Platform for Cystic Fibrosis Drug Development","authors":"A. Berical, M. Beermann, Dylan C. Thomas, N. Ranallo, P. McNally, K. Hurley, S. Randell, D. Kotton, F. Hawkins","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6197","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6197","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117164055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Dehydroepiandrosterone Sulfate (DHEA-S) Levels in Cystic Fibrosis 囊性纤维化患者硫酸脱氢表雄酮(DHEA-S)水平的评价
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6178
L. Shaffer, S. Abid, R. Jain
{"title":"Evaluation of Dehydroepiandrosterone Sulfate (DHEA-S) Levels in Cystic Fibrosis","authors":"L. Shaffer, S. Abid, R. Jain","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6178","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6178","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127318636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Novel Anti-Aging Strategies to Inhibit the Effect of Bronchial Cell Senescence on Mucociliary Dysfunction 新的抗衰老策略抑制支气管细胞衰老对纤毛粘膜功能障碍的影响
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6190
S. Krick, J. Garth, A. Adewale, Ren-Jay Shei, L. Tang, E. Helton, R. Denson, R. Zaharias, G. King, Juliette Sailland, L. Künzi, N. Baumlin, M. Salathé, S. Rowe, J. Barnes
{"title":"Novel Anti-Aging Strategies to Inhibit the Effect of Bronchial Cell Senescence on Mucociliary Dysfunction","authors":"S. Krick, J. Garth, A. Adewale, Ren-Jay Shei, L. Tang, E. Helton, R. Denson, R. Zaharias, G. King, Juliette Sailland, L. Künzi, N. Baumlin, M. Salathé, S. Rowe, J. Barnes","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6190","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6190","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124337245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alpha-1 Antitrypsin Imparts an Anti-Inflammatory Effect Without Increasing Bacterial Burden in Models of Antibiotic-Treated Cystic Fibrosis P. Aeruginosa Infection α -1抗胰蛋白酶在抗生素治疗的囊性纤维化P.铜绿假单胞菌感染模型中具有抗炎作用而不增加细菌负担
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7465
S. Gellatly, N. Schaunaman, S. Caceres, P. Bratcher, K. Ward, D. Nichols, K. Malcolm, H. Chu
{"title":"Alpha-1 Antitrypsin Imparts an Anti-Inflammatory Effect Without Increasing Bacterial Burden in Models of Antibiotic-Treated Cystic Fibrosis P. Aeruginosa Infection","authors":"S. Gellatly, N. Schaunaman, S. Caceres, P. Bratcher, K. Ward, D. Nichols, K. Malcolm, H. Chu","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7465","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7465","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123077425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Tumour Growth Factor-Beta 1 Levels with dF508 Genotype and Clinical Phenotype of Cystic Fibrosis 肿瘤生长因子- β 1水平与dF508基因型和囊性纤维化临床表型的关系
D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6176
M. Singh, S. Sagwal
{"title":"Association of Tumour Growth Factor-Beta 1 Levels with dF508 Genotype and Clinical Phenotype of Cystic Fibrosis","authors":"M. Singh, S. Sagwal","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6176","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6176","url":null,"abstract":"","PeriodicalId":291196,"journal":{"name":"D34. CYSTIC FIBROSIS AND BRONCHIECTASIS: CLINICAL AND MECHANISTIC STUDIES","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122334270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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