Fine Chemical Engineering最新文献

{"title":"Sustainable Starch-Calotropis procera Extract Bio-Packing for Protection Against Fungus Attack and Fruit Fast Maturation","authors":"Ana Júlia Martins Souza, Jordane Silva Rodrigues, Micheli de Souza Bernardes, Fernanda Guerra Lima Medeiros Borsagli","doi":"10.37256/fce.4220232930","DOIUrl":"https://doi.org/10.37256/fce.4220232930","url":null,"abstract":"The proliferation of diseases in plantations, control of fruit ripening, and damages in fruits during transportation are significant agricultural concerns. Thus, this research is based on the production of a sustainable packaging film based on starch conjugated to different concentrations of natural extract from Calotropis procera seeds for agricultural applications. The films were characterized by Fourier Transform Infrared (FTIR), Nuclear Magnetic Resonance (NMR) and Surface Contact Angle. In addition, antifungal activity against Colletotrichum musae were evaluated in vitro and in vivo, as the control of fruit fast maturing were figured using banana as a model of fruit. The cytotoxicity were also analyzed. The results showed that some compounds may have an important role in this protections, as proteins, calactin and calotoxin. Moreover, it demonstrated cytocompatibility using in vitro bioassays (> 80%). The analysis of fruit fast maturing showed that the film with 50 μL·mL-1 of natural extract presented the best results, controlling the fruit ripening and protecting against diseases. Thus, for the first time, a packaging film based on starch and natural extract from Calotropis procera seed demonstrated a versatile action towards agriculture applications.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122306508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Control in Reactive Processing for Fine Chemicals and Polymers in Stirred Jacketed Batch and Semi-Batch Reactors: A Bibliography","authors":"Marija Stojkovic","doi":"10.37256/fce.4220232974","DOIUrl":"https://doi.org/10.37256/fce.4220232974","url":null,"abstract":"After World War II, scientific investigations for processing in chemical batch reactors had been started, for its “most adopted” application in the industrial sector. Taken from the industrial perspective, serious instances, unable to be endured, happen; hence, the process must be in control of, which impedes the realization of batch reactor objectives. Therewithal, with the evolution of large-scale optimization software packages, the “ease” to convert novel optimal control policies into industrial environment strategies, becomes realistic. In this work, a detailed bibliography on the optimal control functioning for reactor configuration named “stirred jacketed”, waged in batch/semi-batch processing of fine chemicals and polymers, along with methods according to this definition, is presented. To the author’s knowledge, all the existing schemes are discussed, focusing on their strong points.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123876405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Novel Bacterial Cellulose Based Silver-Metal Organic Frameworks (BC@Ag-MOF) as Antibacterial Wound Healing","authors":"N. Puspitasari, David Arief, S. Ismadji, V. Saraswaty, S. Santoso, Ery Susiany Retnoningtyas, J. N. Putro, C. Gunarto","doi":"10.37256/fce.4220233120","DOIUrl":"https://doi.org/10.37256/fce.4220233120","url":null,"abstract":"Bacterial Cellulose (BC) is a polymer derived from the bacterium Komagataeibacter xylinus with great potential for biomedical applications due to its high biocompatibility and biodegradability. In addition, the polymer is naturally biosynthesized by bacteria as hydrogels which can be used as optimal substrates for wound healing. However, the drawback of BC is the absence of antibacterial properties. Nowadays, some infections become more prevalent and harder to treat because of antimicrobial resistance, therefore, it is necessary to develop a strategy for modifying BC as wound healing that provides protection against bacterial contamination. In this work, silver-based Metal Organic Frameworks (MOFs) were immobilized into Bacterial Cellulose (BC). MOFs are porous coordination materials consisting of metal ions and multidentate organic ligands that have the potential as a matrix for metal ions due to their ability to gradually release metal ions. The structure and morphology of BC@Ag-MOF were successfully confirmed by Fourier-Transform Infrared spectroscopy (FTIR) and Scanning Electron Microscope (SEM). Evidently, BC@Ag-MOF exhibited a higher silver content (63.19%) than BC@Ag without immobilization into MOF (48.46%). Therefore, it indicated that MOF has large pores for enhancing the capacity for silver ion absorption in BC. The modified BC has never been reported and achieved the highest antibacterial activity of 99.99% against Gram-negative bacteria Escherichia coli. Moreover, BC@Ag-MOF has a higher antibacterial efficiency of 97% compared to BC@Ag without matrix. This study expands the potential application of BC modification in the field of biological antibacterial. has never been reported and achieved the highest antibacterial activity of 99.99% against Gram-negative bacteria Escherichia coli. Moreover, BC@Ag-MOF has a higher antibacterial efficiency of 97% compared to BC@Ag without matrix. This study expands the potential application of BC modification in the field of biological antibacterial.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132874514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Detection of Pharmaceuticals in Hospital Wastewater: A Case of Referral and District Hospitals in Zanzibar","authors":"F. Mpatani, Ussi Makame Kombo, Mayassa Salum Ally, Burhani Simai, Mwanaisha Juma Fakih, S. Mbarak, Hassan Vuai Is-haka, Ali Makame Ame, Shaib Silima Mnemba, Hajra Mohamed Haji, Bariki Salum Juma, Mohammed Hamduni Khamis, Abdul-karim Ahmada Mkanga, Suhaila Samih Muhamed, Juma Othman Bakari, Sauda Rashid Ismail, Ayman Othman Salum, Hassan Hija Hassan, A. A. Aryee","doi":"10.37256/fce.4220233043","DOIUrl":"https://doi.org/10.37256/fce.4220233043","url":null,"abstract":"Despite the great efforts taken by the developed and some developing countries in managing the release of pharmaceuticals from their primary sources to the environment; the pharmaceutical wastewater management in Zanzibar-Tanzania still has not received much attention as a bulk of pharmaceuticals and their metabolites are released to the environment without proper treatment. Therefore, this study has scrutinized the incidence of pharmaceuticals in wastewater released from the referral and district hospitals in Zanzibar, to ascertain the levels of pharmaceuticals present in hospital wastewater. Purposive sampling was implemented to collect a total of seventy-two (72) wastewater samples in a period of six months (March-August 2022). Samples were collected in the effluent of wastewater-streams (Mnazi Mmoja Hospital, MMH) and pit latrines (Kivunge District Hospital (KDH) and Makunduchi District Hospitals (MDH)). The pharmaceuticals in these samples were obtained via the solid phase extraction after which they were analyzed using the LC-tandem MS (Agilent 1,290 LC coupled to 6,460-triple quadrupole MS). The limit of detections (LODs) and limit of quantitations (LOQs) for the determination of pharmaceuticals were in the range of 0.021-0.037 μg L-1 and 0.033-0.059 μg L-1, respectively. The detected analytes belonged to antibiotics, anti-inflammatory, benzodiazepine, antipsychotic, antipyretic and anticonvulsant (anti-epileptic) drugs. Diclofenac (DIC), paracetamol (PCT), ciprofloxacin (CIP), sulfamethoxazole (SMZ) and azithromycin (AZM) were detected at higher concentrations (> 0.25 μg L-1) in wastewater samples collected from KDH and MDH. Lower concentrations of pharmaceuticals (< 0.10 µg L-1) were identified in MMH wastewater samples. These present findings provide estimable information on the incidence of pharmaceuticals in wastewater that can assist in strengthening the environmental strategies for the protection of marine and terrestrial life from pharmaceutical pollution in Zanzibar. ","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134382478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organotitanium Click Chemistry","authors":"Gregory G. Arzoumanidis","doi":"10.37256/fce.4220232854","DOIUrl":"https://doi.org/10.37256/fce.4220232854","url":null,"abstract":"The click chemistry of titanium exemplified by the “green” [3 + 2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising new synthetic approaches discussed herein, for pharmacological and bio orthogonal applications. This prediction is based on emerging click reaction possibilities from newly prepared titanium azides (complex 6), to existing titanium azides, including the commercially available Ti(N3)4, Cp2Ti(N3)2, (iPrO)2Ti(N3)2, and their multiple derivatives, participating in cycloaddition, exchange and other reaction types with alkynes, alkenes, nitriles, and related click synthons. Most of the organotitanium click reactions show nearly quantitative yields, as in the reaction of Ti(OiPr)4 with (CH3)2SiN3. Structural, mechanistic, stereo control and other effects on reactivity are briefly discussed. The main emphasis in this review article is on recently discovered organotitanium complexes like 2-phenylindole titanium dichloride, easily modified by insertion reactions of small molecules like CO2, SO2 or even RN3, serving as springboards of a new era in organotitanium click chemistry, by the original syntheses of non-toxic, potentially bioactive complexes.\u0000 \u0000","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131324557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiphase Particle-in-Cell (MP-PIC) Simulation on Fluidization and Reaction Characteristics in an 80 kW Chemical Looping Gasification Unit","authors":"Q. Guo, C. Shen, Tuo Guo, Xiu-de Hu","doi":"10.37256/fce.4220232796","DOIUrl":"https://doi.org/10.37256/fce.4220232796","url":null,"abstract":"A numerical simulation study of the 80 kW Chemical Looping Gasification (CLG) pilot plant fuel reactor was conducted using the Computational Particle Fluid Dynamics (CPFD) method to investigate the influence of superficial gas velocity, coal particle size and static bed height on the gas-solid fluidization characteristics in the bed. The results showed that the suitable operating ranges were superficial gas velocity in 0.36~0.48 m/s, coal particle size in 0.3~0.4 mm, and static bed height in 0.6~0.8 m, and the CLG process released gas in the whole bed compared with the cold condition, which could effectively alleviate the uneven pressure gradient distribution. In addition, the working conditions with superficial gas velocity higher than 0.36 m/s, coal particle size higher than 0.35 mm and static bed height higher than 0.6 m are more favorable to the full contact between coal particles, oxygen carrier bed particles and gas phase, thus obtaining a higher carbon conversion rate.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130607675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Activity of Extracts from Bidens pilosa-A Medicinal Plant from the Kingdom of Lesotho","authors":"M. Pillai, Mahase Keketso, Rets'epile Paul Matamane","doi":"10.37256/fce.4220232751","DOIUrl":"https://doi.org/10.37256/fce.4220232751","url":null,"abstract":"Bidens pilosa finds therapeutic applications in the traditional medicine. In the present study, we aimed to evaluate the antioxidant activity of various extracts obtained from the leaves and stem-bark of B. pilosa by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and ferric reducing power assay. We also aimed to determine the total phenolic contents (TPCs) by Folin-Ciocalteu colorimetric method and total flavonoid contents (TFCs) by the aluminium chloride colorimetric method. Various solvent extracts were obtained from the leaves and stem-bark of B. pilosa by maceration and hot solvent extraction techniques. The extracts from leaves and stem-bark exhibited radical scavenging activity in the ranges of 4.40 ± 1.02-81.18 ± 1.14% and 5.92 ± 2.16-79.34 ± 8.43%, respectively at concentrations of 200-3,000 µg/mL. The positive control, ascorbic acid exhibited radical scavenging activity in a range of 55.17 ±1.89-88.12 ± 1.31% at the same concentrations. Additionally, the methanol extracts from both leaves and stem-bark were found to be the most potent with IC50 values of 848.54 and < 200 µg/mL, respectively. The positive control, ascorbic acid exhibited an IC50 value < 200 µg/mL. Furthermore, the extracts from the leaves and stem-bark exhibited ferric reducing power in the ranges of 0.095 ± 0.017-1.175 ± 0.084 and 0.093 ± 0.006-1.100 ± 0.065, respectively at concentrations of 5-100 µg/mL. The positive control, ascorbic acid exhibited a ferric reducing power in the range of 0.326 ± 0.00-1.213 ± 0.078 at concentrations of 5-100 µg/mL. In addition, the TPCs of extracts from the leaves and stem-bark were determined to be in the ranges of 9.03 ± 2.34-179.31 ± 0.96 and 10.93 ± 1.04-154.04 ± 2.15 mg GAE/g of DW of extract, respectively. Similarly, the TFCs of extracts from the leaves and stem-bark were determined to be in the ranges 1.28 ± 0.05-29.33 ± 4.19 and 1.89 ± 0.58-27.75 ± 2.67 mg QE/g of DW of extract, respectively. From this study, we concluded that various extracts obtained from B. pilosa showed a moderate to strong radical scavenging and ferric reducing power and possessed a significant amount of TPCs and TFCs.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124655386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies of a Biocompatible Maleimide-Modified Dextran and Hyaluronic Acid Hydrogel System","authors":"Song Jiang, Tianjin Zhang","doi":"10.37256/fce.4220232705","DOIUrl":"https://doi.org/10.37256/fce.4220232705","url":null,"abstract":"This article discussed a novel hydrogel, which was created through Michael addition. Twom precursors Dextran functionalized Maleimide groups (Dex-Mal) and Hyaluronic Acid functionalized thiol groups (HA-SH) were designed, prepared, and characterized by Nuclear Magnetic Resonance (NMR). The formed hydrogels were investigated by gelation time, swelling studies, viscoelastic properties, and degradation rate. Based on gelation time observation, we detected that the hydrogel gelation time could be varied with a diffident weight percentage of precursors. Based on previous research, we measured that 2% Dex-Mal and 2% HA-SH is the optimal formular for the biomedical application and this formular was also investigated by other studies. The swelling study indicated hydrogel has good flexibility and the degradation test indicated hydrogel is biodegradable. The viscoelastic test indicated hydrogel is an elastic solid. From these studies, this novel hydrogel could be potential for biomedical applications.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116512778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Extraction of Ga(III) from Chloride Solution by Mixture of Cyanex 272 and Alamine 336","authors":"Kailun Zhu, Xiaoxi Ding, Jia-xin Jiang, Boning Tian, Qingjie Guo, Lingyun Wang","doi":"10.37256/fce.4120232537","DOIUrl":"https://doi.org/10.37256/fce.4120232537","url":null,"abstract":"Aming to select a suitable system for the synergistic solvent extraction of Ga(III), solvent extraction (SX) experiments were carried out by using acidic organo-phosphorous extractants, namely P204, P507 and Cyanex 272, and their mixtures with neutral extractants (TBP, N503) or amine extractants (Alamine 336). Among the studied mixtures, a remarkable synergistic effect for Ga(III) extraction was resulted by the combination of Cyanex 272 and Alamine 336 and the maximal synergistic enhancement coefficient reached 3.11. Compared to the single Cyanex 272, higher equilibrium pH values were observed when mixture of Cyanex 272 and Alamine 336 was employed. The extraction of hydrogen ions by Alamine 336 during the reaction was considered to be responsible for the synergistic extraction, and thus the the extraction of Ga(III) by Cyanex 272 was promoted. Finally, the synergistic extraction stoichiometry of mixture of Cyanex 272 and Alamine 336 for Ga(III) was projected by slope analysis. Ga(OH)A2 was resulted to be the composition of extracted complexes.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123223628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pressure-Driven Batch Distillation Optimal Control for Ethanol-Water Separation","authors":"Marija Stojkovic","doi":"10.37256/fce.4120232486","DOIUrl":"https://doi.org/10.37256/fce.4120232486","url":null,"abstract":"Ethanol-water separation by pressure-swing batch distillation in a double-batch rectifier system is a process under investigation. In this work, a complete global solution to the optimal control problem in the form of a sequential synthesis of controlled trajectories is derived. During this study, the optimal reflux strategy through cyclic operation was extended to the separation of a second non-ideal minimum boiling azeotrope of industrial importance. The optimal cyclic reflux ratio operating policy, brought significant reductions in time duration, going up to even 50%. Consequently even more significant reductions in energy expenditure, since the derived discontinuous energy function tends to show cyclic “behavior” as well. Lastly, the proposed strategy provides the possibility to highly recover the desired product even within a single period, and finally maybe even the most importantly, flexibility in operating different units within the time frame.","PeriodicalId":289475,"journal":{"name":"Fine Chemical Engineering","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121504625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}