The Journal of ECT最新文献_第8页

Electroconvulsive Therapy in a Patient With Pulmonary Embolism: A Case Report 电休克治疗肺栓塞1例

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000311

J. Dean, C. Coconcea

引用次数: 3

International Society for ECT and Neurostimulation Annual Meeting Abstracts 2016 国际电痉挛和神经刺激学会2016年年会摘要

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000347

A. Takamiya, J. Hirano, R. Pascual-Marqui, S. Kito, M. Mimura, T. Kishimoto

引用次数: 0

Pilot Study of Accelerated Low-Frequency Right-Sided Transcranial Magnetic Stimulation for Treatment-Resistant Depression 加速低频右侧经颅磁刺激治疗难治性抑郁症的初步研究

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000306

P. Tor, V. Galvez, James Goldstein, D. George, C. Loo

{"title":"Pilot Study of Accelerated Low-Frequency Right-Sided Transcranial Magnetic Stimulation for Treatment-Resistant Depression","authors":"P. Tor, V. Galvez, James Goldstein, D. George, C. Loo","doi":"10.1097/YCT.0000000000000306","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000306","url":null,"abstract":"Background Repetitive transcranial magnetic stimulation (rTMS) is an effective option for treatment-resistant depression but requires prolonged repeated daily treatments for 4 to 6 weeks. Pilot studies have showed the possibility of accelerating rTMS safely and efficaciously but thus far only investigated high-frequency left-sided rTMS. We sought to investigate the safety and efficacy of accelerated low-frequency right-sided rTMS. Methods Our study was an open label accelerated rTMS pilot in 7 treatment-resistant patients (4 unipolar, 3 BP). Accelerated rTMS was given over the right dorsolateral prefrontal cortex at 120% of resting motor threshold at 1 Hz, and 900 pulses were delivered per session. A single rTMS treatment was administered on the first day to test for tolerability, followed by 5 rTMS sessions a day for 2 days, then 7 days of daily rTMS sessions. The total course consisted of 16,200 pulses across 18 sessions given over 10 consecutive weekdays. The primary outcomes of interest were self- and clinician-rated depression scores (BDI-II and MADRS). Results All patients successfully and safely completed the accelerated rTMS treatment. MADRS scores decreased significantly by the third day of treatment and BDI II scores by the end of the 10-day treatment. No patients achieved response or remission. Conclusions Accelerated low-frequency right-sided rTMS was a safe and possibly efficacious treatment for treatment-resistant depression. More research is recommended, including a controlled trial with longer duration of exposure, to establish the efficacy of left- and right-sided accelerated rTMS.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114503108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Assessing the Effects of Repetitive Transcranial Magnetic Stimulation on Cognition in Major Depressive Disorder Using Computerized Cognitive Testing 利用计算机认知测试评估重复经颅磁刺激对重度抑郁症认知的影响

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000308

C. Galletly, S. Gill, Ashlee Rigby, Benjamin L. Carnell, P. Clarke

{"title":"Assessing the Effects of Repetitive Transcranial Magnetic Stimulation on Cognition in Major Depressive Disorder Using Computerized Cognitive Testing","authors":"C. Galletly, S. Gill, Ashlee Rigby, Benjamin L. Carnell, P. Clarke","doi":"10.1097/YCT.0000000000000308","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000308","url":null,"abstract":"Objectives A range of different treatment approaches are available for depression; however, there is an ongoing concern about the cognitive impairment associated with many treatments. This study investigated the effect of treatment with repetitive transcranial magnetic stimulation (rTMS) on cognition in patients with major depressive disorder. Cognition before and after treatment was assessed using a computerized cognitive testing battery, which provided comprehensive assessment across a range of cognitive domains. This was a naturalistic study involving patients attending an outpatient clinical rTMS service. Methods A total of 63 patients with treatment-resistant depression completed the IntegNeuro cognitive test battery, a well-validated comprehensive computerized assessment tool before and after receiving 18 or 20 treatments of sequential bilateral rTMS. Change in the various cognitive domains was assessed, and analyses were undertaken to determine whether any change in cognition was associated with a change in rating of depression severity. Results There was a significant decrease in Hamilton Depression Rating Scale scores from baseline to posttreatment. There was no decline in performance on any of the cognitive tests. There were significant improvements in maze completion time and the number of errors in the maze task. However, these were accounted for by improvement in mood when change in depressive symptoms was included as a covariate. Conclusions This open-label study provides further support for the efficacy and safety of rTMS as a treatment option for people with major depressive disorder in a naturalistic clinical setting. Using a comprehensive, robust computerized battery of cognitive tests, the current study indicated that there was no significant cognitive impairment associated with rTMS and that any improvements in cognitive functioning were associated with a reduction in depressive symptoms.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"482 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126385264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

General Anesthesia in a Patient With Urticaria Pigmentosa Referred for Electroconvulsive Therapy. 色素性荨麻疹患者全身麻醉转介电休克治疗。

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000305

Amy Aloysi, Gabriella M. Ahle, E. Geduldig, C. Kellner, E. Bryson

引用次数: 4

Electroconvulsive Therapy in Italy: Will Public Controversies Ever Stop? 意大利电休克疗法:公众争议会停止吗?

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000301

C. Buccelli, P. Di Lorenzo, M. Paternoster, G. D’Urso, V. Graziano, M. Niola

{"title":"Electroconvulsive Therapy in Italy: Will Public Controversies Ever Stop?","authors":"C. Buccelli, P. Di Lorenzo, M. Paternoster, G. D’Urso, V. Graziano, M. Niola","doi":"10.1097/YCT.0000000000000301","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000301","url":null,"abstract":"Background The use of electroconvulsive therapy (ECT) is still very limited in Italy for ideological rather than scientific reasons. Objectives To describe the public controversies surrounding ECT in Italy and to propose a plan of action to resolve the dispute. Methods We describe the historical background and the current public controversies about ECT by reviewing the official documents issued by the entities involved in the debate and by reporting our personal experiences of ECT practice. Results According to the highest legal and health authorities, there are no ethical reasons for doubting the licit nature of ECT. However, because of politically and ideologically based conflicts, public ECT centers are still lacking. The situation could further deteriorate because local initiatives are endeavoring to criminalize and ban the treatment. Conclusions The enactment of specific regulations and guidelines concerning the use of ECT by the Italian government is highly warranted to increase the availability of the treatment. Education and information campaigns must strive to increase the knowledge of health professionals and the lay public regarding the safe and beneficial use of ECT.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131620108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Demographic and Clinical Profile of Patients With Dementia Receiving Electroconvulsive Therapy: A Case-Control Study 痴呆患者接受电休克治疗的人口学和临床特征:一项病例对照研究

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000314

Qinge Zhang, S. Sha, G. Ungvari, H. Chiu, C. Ng, Hong-bo He, B. Forester, Y. Xiang

{"title":"Demographic and Clinical Profile of Patients With Dementia Receiving Electroconvulsive Therapy: A Case-Control Study","authors":"Qinge Zhang, S. Sha, G. Ungvari, H. Chiu, C. Ng, Hong-bo He, B. Forester, Y. Xiang","doi":"10.1097/YCT.0000000000000314","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000314","url":null,"abstract":"Purpose Little is known about the clinical characteristics of patients with dementia receiving electroconvulsive therapy (ECT) for the treatment of behavioral symptoms. This study examined the demographic and clinical profile of patients with dementia receiving ECT in China. Methods This was a retrospective, case-control study. The sample was composed of 23 patients with dementia treated with ECT and 71 sex- and age-matched controls treated for a period of 8 years (2007–2014) at the National Clinical Research Centre of Mental Disorders, China. Sociodemographic and clinical data were collected from the electronic chart management system. Results Multiple logistic regression analysis revealed that ECT was independently associated with high risk for suicide at admission. The recorded indications for ECT included both high risk for suicide and aggressive behavior. Most patients responded to ECT satisfactorily (56.5%) or partially (34.8%) with only mild-moderate transient memory impairment (30.4%). Conclusions Although this is a preliminary study limited by the retrospective design and small sample size, findings suggest that ECT is an effective and safe therapeutic intervention to reduce the risk for suicide and aggressive behavior in dementia.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124438966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Ketamine Anesthesia, Efficacy of Electroconvulsive Therapy, and Cognitive Functions in Treatment-Resistant Depression 氯胺酮麻醉，电休克治疗的疗效，和治疗难治性抑郁症的认知功能

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000317

J. Rybakowski, A. Bodnar, M. Krzywotulski, M. Chłopocka‐Woźniak, M. Michalak, J. Rosada-Kurasińska, A. Bartkowska-Śniatkowska

{"title":"Ketamine Anesthesia, Efficacy of Electroconvulsive Therapy, and Cognitive Functions in Treatment-Resistant Depression","authors":"J. Rybakowski, A. Bodnar, M. Krzywotulski, M. Chłopocka‐Woźniak, M. Michalak, J. Rosada-Kurasińska, A. Bartkowska-Śniatkowska","doi":"10.1097/YCT.0000000000000317","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000317","url":null,"abstract":"Objectives Electroconvulsive therapy (ECT) is the most effective treatment for drug-resistant depression (DRD). Because a single infusion of ketamine may exert both a rapid antidepressant effect and a quick improvement of cognition, the aim of the present study was to assess whether ketamine, as an anesthetic drug for ECT, can augment the antidepressant activity of the procedure and/or exert a beneficial effect on cognition. Methods A total of 11 male and 34 female patients with DRD, aged 21 to 75 years, were included in the study. Fifteen patients (group 1) received only thiopental anesthesia, 15 patients (group 2) had their second and third ECT sessions with ketamine, and 15 patients (group 3) had ketamine for the second, fourth, sixth, eighth, and tenth sessions. Depression intensity was measured by the 17-item Hamilton Depression Rating Scale. Cognitive functions were measured before and after ECT, assessing visual-spatial abilities, verbal auditory memory, working memory, and executive functions. Results Before the ECT, the mean (SD) intensity of depression was 32 (6) points on the Hamilton Depression Rating Scale and the mean number of ECT sessions was 10.8 (1.5), with no difference between groups. After the last ECT session, the intensity of depression was significantly lower in group 3, compared with group 1. Cognitive assessments after ECT showed a more marked worsening in verbal memory in patients with added ketamine anesthesia. Conclusions The addition of ketamine may be connected with better antidepressant efficacy of ECT, compared with only thiopental anesthesia. However, patients with added ketamine had worse results on some of the indices measuring verbal memory.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129712784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Safe and Successful ECT in a Female-to-Male Transgender Individual With Major Depression. 安全而成功的电痉挛治疗患有重度抑郁症的女变男变性人。

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000307

M. Coffey, J. Stevens

引用次数: 4

Effects of Electroconvulsive Therapy on Some Inflammatory Factors in Patients With Treatment-Resistant Schizophrenia 电休克治疗对难治性精神分裂症患者某些炎症因子的影响

The Journal of ECT Pub Date : 2016-09-01 DOI: 10.1097/YCT.0000000000000303

S. Kartalci, A. Karabulut, L. Erbay, C. Acar

{"title":"Effects of Electroconvulsive Therapy on Some Inflammatory Factors in Patients With Treatment-Resistant Schizophrenia","authors":"S. Kartalci, A. Karabulut, L. Erbay, C. Acar","doi":"10.1097/YCT.0000000000000303","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000303","url":null,"abstract":"Objectives Electroconvulsive therapy (ECT) is the most effective option for several psychiatric conditions, including treatment-resistant schizophrenia. However, little is known about the molecular mechanism of action of ECT. The link between inflammatory system and schizophrenia is the focus of recent studies. However, the impact of ECT on inflammatory functioning in this disorder remains elusive. Whether ECT could modulate inflammatory factors in patients with schizophrenia was examined. Methods Plasma levels of interleukin-4 (IL-4), transforming growth factor-&bgr; (TGF-&bgr;), myeloperoxidase (MPO), and nuclear factor-&kgr;B (NF-&kgr;B) activation were analyzed in 20 schizophrenic patients, mainly with resistant to antipsychotic medication disorders, and in 20 sex- and age-matched healthy controls. Disease severity was evaluated using the Brief Psychiatric Rating Scale. All patients were followed with measurement of the inflammatory factors before and after ECT treatment and compared with the controls. Results Patients with schizophrenia had markedly raised NF-&kgr;B and but decreased TGF-&bgr; levels compared with healthy controls. On the other hand, no significant differences were found for the levels of IL-4 and MPO levels. The clinical improvement during repeated ECT was accompanied by a gradual and significant increase in IL-4 and TGF-&bgr; level, but MPO and NF-&kgr;B activation were left unaffected. Increases in TGF-&bgr; were negatively correlated with the change in Brief Psychiatric Rating Scale scores after ECT. Conclusions It is shown that ECT, while increasing the anti-inflammatory response such as the levels of IL-4 and TGF-&bgr;, it did not affect the levels of MPO and NF-&kgr;B activation in this study.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127306856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20