International Journal of Medical and All Body Health Research最新文献

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Healthy lifestyles and their beneficial effects on sexual function and dysfunction 健康的生活方式及其对性功能障碍的有益影响

International Journal of Medical and All Body Health Research Pub Date : 2021-12-31 DOI: 10.54660/ijmabhr.2021.3.1.1

S. Agarwal

引用次数: 0

Unhealthy lifestyles and their deleterious relationship with infections: A Narrative Review 不健康的生活方式及其与感染的有害关系:叙述性回顾

International Journal of Medical and All Body Health Research Pub Date : 2021-12-18 DOI: 10.54660/ijmabhr.2021.2.4.2

S. Agarwal

引用次数: 0

Recent advances in stem cell therapy for Parkinson’s Disease: A Review 干细胞治疗帕金森病的最新进展

International Journal of Medical and All Body Health Research Pub Date : 2021-12-01 DOI: 10.54660/ijmabhr.2021.2.4.1

Mohammed Ashif, Nuseba Shehla Jeelani K, V. J, S. K., M. J

{"title":"Recent advances in stem cell therapy for Parkinson’s Disease: A Review","authors":"Mohammed Ashif, Nuseba Shehla Jeelani K, V. J, S. K., M. J","doi":"10.54660/ijmabhr.2021.2.4.1","DOIUrl":"https://doi.org/10.54660/ijmabhr.2021.2.4.1","url":null,"abstract":"Parkinson's disease (PD) is a degenerative neurological condition characterized by tremor, bradykinesia, and stiffness as cardinal motor characteristics. It's linked to a long-term loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc), resulting in a severe DA shortage in the striatum, which is necessary for motor function. There is presently no cure for Parkinson's disease, and the majority of treatments aimed at reversing dopamine depletion and alleviating symptoms. The transplantation of stem cells or stem cell derived progenitors has highlighted the potential of employing cell-based therapy to replace lost cells in the sick brain, based on promising findings from early experiments. Embryonic stem cells (ESCs) are highly expandable and pluripotent cells that can differentiate into any cell type in the human body, including nervous system tissues, suggesting that they could provide a long-term treatment for Parkinson's disease and other neurological illnesses. However, because of the potential for safety and ethical difficulties involved with the use of undifferentiated ESCs in people, other sources of transplantable cells must be considered. Another method is to use external manipulation to stimulate endogenous stem cells to heal the brain. Recent advances in stem cell research in Parkinson's disease will be discussed in this review, which will provide an overview of the various sources and strategies such as the use of different stem cell populations for cell replacement and possible modulation of endogenous stem cells, that have the potential to provide effective cell-based therapy in the future.","PeriodicalId":286585,"journal":{"name":"International Journal of Medical and All Body Health Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114573032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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