S. Zafar, Kashif Rahim, I. Khan, Muhammad Yasin, M. Dawood, S. Saleha
{"title":"Prevalence and Association of Diabetic Retinopathy with Diabetic Foot Ulcer: A Cross-Sectional Observational Study","authors":"S. Zafar, Kashif Rahim, I. Khan, Muhammad Yasin, M. Dawood, S. Saleha","doi":"10.5772/INTECHOPEN.82667","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82667","url":null,"abstract":"We aimed to elucidate prevalence and association of diabetic retinopathy (DR) in patients with diabetic foot ulcer (DFU) from Pakistan. In this cross-sectional study, about 225 DFU patients who underwent ophthalmic examinations within 6 months of diagnosis of foot ulceration were included. The medical records of 305 diabetic patients without DFU were included as controls. The association of DR with DFU was assessed by comparing DFU patients with proliferative DR (PDR) and DFU patients without PDR. Out of 225 DFU patients, 215 patients (95.6%) had DR and 169 patients (75.1%) had PDR. The prevalence of DFU was significantly greater (P = 0.0527) among the male diabetic patients, whereas advanced age of these patients (≥41 years) had a significant effect (P = 0.0286) on development and progression of PDR. A longer duration of diabetes (≥10 years) was identified as a significant contributing factor for the development of both DFU (P = 0.0029) and PDR (P = 0.0299). Moreover, the risk of PDR increased in diabetic patients with higher DFU grades (grade 3 and grade 4). In conclusion, retinopathy was prevalent in DFU patients. Therefore, DFU patients with advancing age and longer duration of diabetes should undergo retinal examinations for timely diagnosis and management of DR.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121450893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in Vitreoretinal Surgery","authors":"B. Komur","doi":"10.5772/INTECHOPEN.83019","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.83019","url":null,"abstract":"","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128187903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Topical NSAIDs in Prevention of Postcataract Macular Edema","authors":"Ahmed A Alnagdy, A. M. Eissa, Amr M. El-Kannishy","doi":"10.5772/INTECHOPEN.82321","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82321","url":null,"abstract":"Postoperative macular edema is considered one cause of diminished vision after cataract surgery. It was approved that inflammatory mediators especially prostaglandins play a key role in macular edema formation especially in the presence of risk factors that affect blood-retinal barrier such as diabetes, uveitis, tear of posterior capsule, and vitreous loss. So, anti-inflammatory medications like corticosteroids and NSAIDs are the cornerstone of macular edema managements. In spite of using corticosteroids as gold standard for treatment of ocular inflammation, they cannot be used for prolonged period due to associated adverse effects. Lastly, there were many studies about benefits of NSAIDs in management and prevention of macular edema to avoid the side effects of corticosteroids.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131206471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Nasolacrimal Duct Obstruction and the Visual System","authors":"A. Saleem","doi":"10.5772/INTECHOPEN.82546","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82546","url":null,"abstract":"Congenital nasolacrimal duct obstruction (CNLDO), previously considered a benign disease, affects 20% of the children globally. It is described by a collection of symptoms in which continuous epiphora and intermittent discharge are present in either one or both the eyes. CNLDO usually resolves in most healthy infants in the first few couple of months; however, it may persist for a number of years in some children. There has been a lot of recent deliberation on how a constant watery eye affects the visual development during the phase of emmetropization in children. A connection between CNLDO and anisometropia has been hypothesized. Multiple factors which include developmental and environmental aspects are thought to play a contributory role in the development of anisometropia by and large; particularly hypermetropic anisometropia, raising the chances of developing amblyopia in children with CNLDO. Published literature on CNLDO had shown inconclusive evidence on this anecdotal propinquity. This chapter discusses CNLDO; etiology, pathogenesis, treatment modalities, surgical intervention, and its role in inducing refractive errors; and its propensity to cause amblyopia.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134034777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corneal Dystrophies and Degenerations","authors":"H. Alkatan, Norah F. Alkheraiji, Tariq A Alzahem","doi":"10.5772/INTECHOPEN.84426","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.84426","url":null,"abstract":"The cornea is a complex structure with complex functions aiming to protect the internal ocular tissues and transmit and refract the coming light rays. Corneal dystrophies are a group of relatively infrequent genetic corneal disorders in which an abnormal material accumulates in the cornea causing variable loss of its clarity. On the other hand, corneal degenerations are more common and usually result from physiologic changes related to aging, particular disease, or long-standing environmental insults to the cornea. Ectatic corneal disorders are usually characterized by bilateral loss of corneal biomechanical strength leading to progressive thinning and bulging of the cornea with resultant astigmatism and decreased visual acuity. In this chapter, we will describe the basic embryological, anatomical, histologic, and physiological features of the cornea. Then, we will go over the clinical, histopathologic, medical, and surgical aspects of dystrophic, degenerative, and ectatic corneal disorders.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117312025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical Coherence Tomography in the Management of Glaucoma and Macular Diseases","authors":"L. Abdu","doi":"10.5772/INTECHOPEN.82657","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82657","url":null,"abstract":"Optical coherence tomography (OCT) is a non contact, non invasive and repro-ducible imaging technique that produces thin slices of tissue section images. OCT identifies retinal nerve fiber damage before detection of visual field changes making it a handy and effective tool in early detection and monitoring in glaucoma. Retinal fiber layer thickness measurements provide vital knowledge of extent of neural damage. This enables the clinician to counsel the patient and take the best decision towards achieving glaucoma control. Early and quantifiable macular thickness measurements are obtained, allowing for detection of clinically significant diabetic macular edema. OCT allows monitoring of the impact of laser or other interventions. Changes in age-related macular degeneration are relatively easily determined and impact of treatment interventions monitored. In conclusion, OCT is a vital emerging tool in the evaluation and management glaucoma and macular diseases in all parts of the World, including low income countries of sub-Saharan Africa.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115938322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Evaluation of Horizontal Pediatric Strabismus and the Management Challenges","authors":"L. Abdu","doi":"10.5772/INTECHOPEN.82547","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82547","url":null,"abstract":"Pediatric strabismus is not uncommon. Poor knowledge and religious and cultural practices result in inattention to the child’s need and stigmatization. Horizontal strabismus consisting of esotropia and exotropia constitutes the common types presenting. Childhood ocular deviations are associated with uncorrected refractive errors, diseases causing obstruction of the visual axis such as cataract, and intra ocular tumors commonly retinoblastoma. In parts of the developing world, there is poor documentation and recollection of medical events at family and community levels. Squint in a child is not a painful dramatic condition that can prompt quick action from the parents or caregiver. There is generalized inequity in access to health care. Pediatric ophthalmic services are at best in developmental stage, and purpose design service centers are quite few. Neglect of the causes and timely treatment of amblyopia can retard child’s development resulting in depen-dency and aggravation of poverty circle. A comprehensive approach to management of childhood eye diseases including strabismus is desirable in the low income developing countries. Provision of health insurance as a citizen’s right will reduce most of the health challenges.","PeriodicalId":286438,"journal":{"name":"Frontiers in Ophthalmology and Ocular Imaging","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126617874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}