Topical NSAIDs in Prevention of Postcataract Macular Edema

Postoperative macular edema is considered one cause of diminished vision after cataract surgery. It was approved that inflammatory mediators especially prostaglandins play a key role in macular edema formation especially in the presence of risk factors that affect blood-retinal barrier such as diabetes, uveitis, tear of posterior capsule, and vitreous loss. So, anti-inflammatory medications like corticosteroids and NSAIDs are the cornerstone of macular edema managements. In spite of using corticosteroids as gold standard for treatment of ocular inflammation, they cannot be used for prolonged period due to associated adverse effects. Lastly, there were many studies about benefits of NSAIDs in management and prevention of macular edema to avoid the side effects of corticosteroids.