Journal of Natural Product Research and Applications最新文献

{"title":"Effect of Ammodaucus leucotrichus Coss. & Dur. Essential Oil on the Viability of Erythrocytes and its Antiradical Activity Assessment","authors":"Imad Abdelhamid El HACI, Wissame MAZARI, Fawzia ATIK-BEKKARA","doi":"10.46325/jnpra.v1i02.14","DOIUrl":"https://doi.org/10.46325/jnpra.v1i02.14","url":null,"abstract":"Plants for medicinal purposes are considered as the main source of health care for the majority of the world population. In order to promote medicinal plants in Algeria, the present work aimed to assess the physico-chemical characterization, hemolytic, and antioxidant activities of Ammodaucus leucotrichus essential oil of an endemic plant from south-west of Algeria. The plant was harvested from the region of Bechar (south-west of Algeria). The oil was obtained by hydrodistillation method using Clevenger apparatus. The antioxidant activity of the oil was carried out using DPPH scavenging assay, and its effect on erythrocyte cells was evaluated by measuring the hemolytic degree. The obtained results showed that this oil presented a low antioxidant activity compared to positive control (ascorbic acid). The hemolytic activity was very low since the oil diluted to 1/10, while it was low in the pure state. This fact proves the safety of A. leucotrichus oil, which can explain its use without risk by the indigenous population. \u0000REFERENCES: \u0000Abu Zarga, M.H., Al-Jaber, H.I., Baba Amer, Z.Y., Sakhrib, L., Al-Qudah, M.A., Alhumaidi, J.Y.G., Abaza, I.F., & Afifi, FU. (2013). Chemical composition, antimicrobialand antitumor activities of essential oil of Ammodaucus leucotrichus growing in Algeria.Journal of Biologically Active Products from Nature, 3, 224–231.http://doi.org/10.1080/22311866.2013.833469.Adorjan, B., & Buchbauer, G. (2010). Biological properties of essential oils: An updatedreview. Flavour and Fragrance Journal, 25, 407–426. http://doi.org/10.1002/ffj.2024.AFNOR. (1992). Association Française de Normalisation «Recueil des normes françaises surles huiles essentielles». II édition, Paris.Amorati, R., Foti, M.C., & Valgimigli, L. (2013). Antioxidant activity of essential oils.Journal of Agricultural and Food Chemistry, 61, 10835–10847.http://doi.org/10.1021/jf403496k.Bakkali, F., Averbeck, S., Averbeck, D., Idaomar, M. (2008). Biological effects of essentialoils- a review. Food and Chemical Toxicology, 46, 446–475.http://doi.org/10.1016/j.fct.2007.09106.Barao Paixao, V.L., & de Carvalho, J.F. (2021). Essential oil therapy in rheumatic diseases:A systematic review. Complementary Therapies in Clinical Practice, 43, 101391.http://doi.org/10.1016/j.ctcp.2021.101391Benhouhou, S. (2005). A Guide to Medicinal plants in North Africa: database on Medicinalplants, IUCN center for Mediterranean cooperation. Mâlaga.Bouaziz, M., Yangui, T., Sayadi, S., & Dhouib, A. (2009). Disinfectant properties of essentialoils from Salvia officinalis L. cultivated in Tunisia. Food and Chemical Toxicology, 47,2755–2760. http://doi.org/10.1016/j.fct.2009.08.005.Burt, S. (2004). Essential oils: their antibacterial properties applications in foods-a review.International Journal of Food Microbiology, 94, 223–253.http://doi.org/10.1016/j.ijfoodmicro.2004.03.022.Conforti, F., Sosa, S., Marrelli, M., Menichini, F., Statti, G.A., Uzunov, D., Tubaro, A., &Menichini, F. (2009). The pro","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115096904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Activity and Hemolytic Effect of Hydro-methanolic Extract and its Phenolic Enriched Fractions From Leaves and Stems of Salvia officinalis L. from Algeria","authors":"Souad MAHDI, Rachid AZZI, Farid Boucif LAHFA","doi":"10.46325/jnpra.v1i02.12","DOIUrl":"https://doi.org/10.46325/jnpra.v1i02.12","url":null,"abstract":"This study aimed to assess an in vitro antioxidant and hemolytic activities of crude hydromethanolic extract, ethyl acetate and n-butanol fractions from leaves and stems of Salvia officinalis L. Extract and fractions prepared by maceration from S. officinalis were determined for their phytochemical composition and their contents in total phenolic and flavonoid. Antioxidant activity was evaluated by the methods of DPPH radical scavenging, ferric reducing antioxidant power and total antioxidant capacity. Hemolysis assay was carried out to evaluate the toxicity of the studied samples. Crude extract and fractions from S. officinalis contain different secondary metabolites and considerable contents of phenolic and flavonoids. They exhibit high antioxidant activity and low hemolytic effect. However, ethyl acetate fraction is characterized by the highest total phenolic (362.75 ± 0.07 µg GAE/mg DE) and flavonoid (263.27 ± 0.1 µg CE/mg DE) contents. Furthermore, this fraction shows the best antioxidant activity tested by DPPH, FRAP and TAC assays. The antiradical activity of ethyl acetate fraction against DPPH (IC50 = 208.51 ± 5.77 μg/mL) is close to that of ascorbic acid (IC50 = 206.43 ± 4.16 μg/mL). It exhibits a powerful activity to reduce iron (EC50 = 250 ± 0.001 μg/mL) and the best total antioxidant capacity (817.33 ± 0.06 μg/mL). It reveals the lowest hemolysis rate of 3.77 ± 0.02% with 200 mg/mL of fraction, after one hour of incubation. The obtained results suggest that crude extract, ethyl acetate and n-butanol fractions from Salvia officinalis L. are considered efficient natural antioxidants and safe for human erythrocytes. \u0000REFERENCES: \u0000Andrei, M., Cadmiel, M., Simone, C., Marcello, L., Marina, S., & Gianina, C. (2018).Determination of phenolic compounds in different species of salvia from Romania(Salvia transsylvanica, Salvia glutinosa, Salvia officinalis) and their biologicalactivities. Acta Medica Marisiensis, 64, 14.Bruneton, J. (1999). Pharmacognosie-Phytochimie-Plantes médicinales, 3ème édition, Tec &Doc. Lavoisier: Paris.Burci, L.M., da Silva, C.B., Rondon, J.N., da Silva, L.M., de Andrade, S.F., Miguel, O.G., deFátima Gaspari Dias, J., & Miguel, M.D. (2019). Acute and subacute (28 days) toxicity,hemolytic and cytotoxic effect of Artocarpus heterophyllus seed extracts. ToxicologyReports, 6, 1304–1308. https://doi.org/10.1016/j.toxrep.2018.02.006Cheng, K., Dong, W., Long, Y., Zhao, J., Hu, R., Zhang, Y., & Zhu, K. (2019). Evaluation ofthe impact of different drying methods on the phenolic compounds, antioxidant activity,and in vitro digestion of green coffee beans. Food science and nutrition, 7(3), 1084–1095. https://doi.org/10.1002/fsn3.948Dandlen, A.S., Sofia Lima, A., Marta Mendes, D., Graça Miguel, M., Leonor Faleiro, M.,João Sousa, M., Pedro Luis, G., Barroso José, G., & Cristina Figueiredo, A. (2010).Antioxidant activity of six Portuguese thyme species essential oils. Flavour andfragrance journal, 25(3), 150–155. https://doi.org/ 10","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114379626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Household and related waste management challenges and opportunities Case of Bujumbura - Burundi","authors":"Fridolin NZAMBIMANA, Wael El ZEREY, Asma El ZEREY-BELASKRI","doi":"10.46325/jnpra.v1i01.6","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.6","url":null,"abstract":"Cities in developing countries have been struggling with households and related waste management due to galloping demography, uncontrolled urbanisation, enhanced economic activities, unsuitable environmental governance, low technical and financial capacities, etc. The city of Bujumbura is not an exception. The Government of Burundi developed and made public the National Sanitation Plan, which unfortunately did not improve the household and related waste management service in Bujumbura. This paper attempts to analyse challenges and opportunities of the solid waste sector in Bujumbura through the SWOT scheme and to provide some lasting solutions by favouring a sustainable approach to integrated management of households and related waste based on formal structures through the strengthening and revitalisation of the public-private partnership and informal structure through its recognition and its integration into the solid waste management system.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"798 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123909550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study of serum biochemical parameters between diabetic patients using medicinal plants and those using only conventional treatment in the rural region of the province of Tlemcen (North-western Algeria)","authors":"Rachid AZZI, Dounia MEZOUAR, Fayza ABBOU, Souad MAHDI, Nacéra BELKACEM, Nabila BENARIBA, Farid Boucif LAHFA","doi":"10.46325/jnpra.v1i01.3","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.3","url":null,"abstract":"A survey is carried out on 148 diabetic patients from rural Fellaoucene, Tlemcen Province (North-Western Algeria). The main interest of this study is to determine the frequency of diabetic patients using medicinal plants with their conventional medication to relieve their diabetes mellitus and to compare their serum biochemical parameters with patients do not use these plants in combination with drugs. A questionnaire is used to collect information about patients (age, sex), diabetes (duration, type, treatments, and complications), antidiabetic plants use (vernacular, scientific names) and variation of some serum biochemical parameters (glycemia, triglyceride, cholesterol, urea, creatinine, glycated hemoglobin (HbA1c)). 72% of diabetic patients are type 2 diabetes mellitus and 77% of them are women with a mean age of 53 years. More than 26% of the cases are suffering from diabetes for more than 10 years. 96% of the patients are affected by at least one chronic complication. The results show that 21% of diabetics use medicinal plants without any significant effects on the balance of the biochemical parameters tested. We notice a slight increase in glycemia (1.39±0.48 g/l) and HbA1c (7.27±0.69 %) of both populations when compared to the values recommended by WHO (1.26 g/l and 6.5%, respectively). The medicinal plants still have a place in the treatment of diabetes mellitus in the rural region of Fellaoucene, Tlemcen (Algeria)","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130743570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological activities of Pituranthos scoparius essential oil from Algeria","authors":"Charaf Eddine Watheq MALTI, Maghnia BOUSSAÏD, Imad Abdelhamid El HACI, Pierre TOMI, Félix TOMI, Chahrazed BEKHECHI","doi":"10.46325/jnpra.v1i01.1","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.1","url":null,"abstract":"The essential oil from aerial parts of Pituranthos scoparius obtained by hydrodistillation was analyzed by GC, GC/MS and 13C NMR and evaluated for antimicrobial and antioxidant activities. The yields were showed a very high variability ranging from 0.16 to 0.99%. Sixty two components were identified and the results indicated that the essential oil was rich in hydrocarbons monoterpenes and phenylpropanoid compounds. 6-Methoxyelemicine (0.1- 47.0%), sabinene (1.4-35.5%), limonene (0.6-24.0%), myristicine (0.2-18.9%), α-pinene (3.1- 14.7%) and dill apiole (0.0-10.6%) were the major compounds. The essential oils were tested against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Klebsiella pneumonia, Candida albicans, Fusarium oxysporum, Aspergillus fumigatus and Aspergillus flavus and the minimum inhibitory concentration was determined. The tested oils have been shown to possess inhibitory action in the range from 2 to 3 µL/mL against Aspergillus fumigatus, Staphylococcus aureus and Candida albicans. The antimicrobial activity of essential oil from P. Scoparius well be due probably to the presence of synergy between myristicine and terpinen-4-ol. The antioxidant activity was evaluated through DPPH assay. All samples exhibited weak scavenging activity against DPPH, compared to standard antioxidant tested. Essential oil with IC50 of the order of 23.65±0.77 and 25.95±2.13 mg/mL could be attributed probably to the presence of limonene and germacrene D in larger amounts.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126995364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of nutrition coaching on glycemic balance in diabetic patients","authors":"Zoubida MAMI-SOUALEM, Fayçal YEZLI, Fatima Zohra GHANEMI, Meryem BERRICHI, Meriem BELARBI","doi":"10.46325/jnpra.v1i01.4","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.4","url":null,"abstract":"Regardless of the associated pharmacological treatment modality, hygienic-dietary measures, focusing on lifestyle modification (diet and physical activity), represent the basis of the management of type 1 and type 2 diabetes. In order to ensure that these dietary measures are effective and long lasting, their implementation and follow-up require guidance. This work focuses on nutrition coaching based on a low glycemic index (GI) diet proposed to type 2 diabetics with the aim of reducing postprandial glycemia in the direction of a better balance to help prevent micro and macro-vascular complications. This method is easy to follow and does not require high restrictions, it allowed us to significantly lower glycated hemoglobin (HbA1c) by 0.92% after a 12-week follow-up (P < 0.05). However, the control diabetic patients who did not benefit from the coaching did not show any significant difference before and after the 12-week experiment.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132940015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemistry and Pharmacology of Ceratonia siliqua L. leaves","authors":"Fatima Zohra GHANEMI, Meriem BELARBI","doi":"10.46325/jnpra.v1i01.7","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.7","url":null,"abstract":"Ceratonia siliqua commonly known as carob belongs to the Fabaceae (Legumunosae). Its original habitats are the western parts of Asia, but after its domestication, it spread to all Mediterranean Basin and then to the western shores of the Americas, South Africa and southern regions of Australia. This review is devoted to health benefits of the carob leaf which are attributed in particular to its phytochemical constituents such as quercetin and gallic, coumaric, chlorogenic acids. Extracts from carob leaves (CLs) have been investigated for their biological activities including anti-cholestinerase, anti-inflammatory, Antidiarrhoeal, anti-tumor, anti-cancer, antimicrobial, hepatoprotective, nephroprotective, antidiabetic and antiobesity as well as phytochemical profile and nutritive value of the CLs. Hence, extracts from Ceratonia siliqua L. leaves, a huge source of bioactive compounds, exhibit a panoply of biological properties. Thus, leaves can be used as a functional food or as a phyto-pharmaceutical herbal-type product. However, it would be wise to undertake clinical trials to prove the efficacy of carob leaf extracts.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132635777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid identification analysis of chemical constituents of Sedum villosum L. (Orpin.) by UHPLC-DAD-HRSM","authors":"Nassira GHEMBAZA, Nabila BELYAGOUBI-BENHAMMOU, Amel ZITOUNI, Fethi TOUL, Serge MICHALET, Fawzia ATIK- BEKKARA","doi":"10.46325/jnpra.v1i01.2","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.2","url":null,"abstract":"In the present paper, we are interested, for the first time, to separate and identify two glycosyl the flavones from Sedum villosum L, family Crassulaceae collected in the flowering phase in Lakhdar Oued, village of Tlemcen (Algeria). The crude methanolic extract of the flowers part was fractionated on column chromatography, and eluted with dichloromethane/methanol each time with increasing polarity of methanol; 24 fractions were separated. One of these fractions named F16 showed more antioxidant activity to scavenge DPPH free radical with percentage inhibition of 94.849 %. F16 was separated by thin-layer chromatography (TLC) to give 10 compounds. We were chosen the sub-fractions F16.8, which has antioxidative activity of 77.02 %, provided two major molecules of glycosyl the flavones, analysed by ultra-highperformance liquid chromatography coupled to mass spectrometry (UHPLC-DAD-HRSM). Compound 1 was identified as 7, 3'-dihydroxyflavone-5-O-dihexosyl-4'-O-deoxyhexose and compound 2 was 7, 3'-dihydroxyflavone-5-O-hexose- 4'-O-deoxyhexose.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122263835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical parameters of oil extracted from Ricinus communis L. seeds","authors":"Tarik Mohammed CHAOUCHE, Farah HADDOUCHI, Ouhiba BOUDJEMAI, Imane GHELLAI, Souad SENHADJI","doi":"10.46325/jnpra.v1i01.5","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.5","url":null,"abstract":"The objective of our work in this study is the extraction and characterization of castor oil (Ricinus communis L) physicochemical characterization for a better appreciation of the oil. Extraction of The castor bean oil is made by the chemical method Soxhlet (extracted with petroleum ether) gave an oil yield of the order of 29.17% and for the results of the physicochemical parameters the values are as follows: Acid value is 0.57mg KOH/g oil, acidity is 0.28%, saponification number is 177.42 mg KOH/g oil, 93.39g/100g Oil for the iodine value and 7.83 meq of active O2 / Kg of oil for the peroxide number, the density being 0.956 at 20°C, the refractive index at 20°C equal to 1.4778 And the rotation angle is 4.20. Finally, a study of the antioxidant activity of the oil was carried out by the method of trapping the free radical DPPH, the results obtained showed the existence of a less important antioxidant activity (IC50 = 431.73 μg/ml) for Castor seed oil versus antioxidant references.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130877079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications of essential oils in medical field: progression of publications in PubMed database","authors":"Benameur NEHAR","doi":"10.46325/jnpra.v1i01.8","DOIUrl":"https://doi.org/10.46325/jnpra.v1i01.8","url":null,"abstract":"The research and the application of natural substances such as essential oils in medical field knew a progression around the world. The purpose of our work is to study the evolution of research publications on essential oils in the medical field. This study is conducted by using the PubMed database in a period from 1945 to 2018. Our results show a number of 12619 worldwide publications on essential oils in the medical field since 1945, the number of which began with a dozen of publications and reached a peak of 819 publications in 2016. The sub domains concern 6905 in dietary supplements, 4775 in toxicology, 1796 in veterinary science, 1629 publications in the field of cancer, 39 on AIDS. 4536 bearing on the animal species and 3095 on the human species. The majority of these publications are journal articles. Overall, we counted 101 publications in Tunisia, 85 in Turkey, 54 in Algeria; 51 in Egypt; 39 in Morocco, 37 in Spain, 31 in France and 12 in Germany. In Algeria, publications based on PubMed were started in 2008 with 24 publications in the last five years.","PeriodicalId":286353,"journal":{"name":"Journal of Natural Product Research and Applications","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128872027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}